PubMed

Early Detrimental Metabolic Outcomes of rs17300539-A Allele of ADIPOQ Gene Despite Higher Adiponectinemia.

Morandi A, Maffeis C, Lobbens S, Bouatia-Naji N, Heude B, Pinelli L, Meyre D, Froguel P.

Obesity (Silver Spring). 2009 Nov 5. [Epub ahead of print]PMID: 19893502 [PubMed - as supplied by publisher]Related articles

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Francès F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Järvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE.

PLoS Genet. 2009 Oct;5(10):e1000694. Epub 2009 Oct 23.PMID: 19851442 [PubMed - in process]Related articlesFree article

The Imprinted Gene Neuronatin Is Regulated by Metabolic Status and Associated With Obesity.

Vrang N, Meyre D, Froguel P, Jelsing J, Tang-Christensen M, Vatin V, Mikkelsen JD, Thirstrup K, Larsen LK, Cullberg KB, Fahrenkrug J, Jacobson P, Sjöström L, Carlsson LM, Liu Y, Liu X, Deng HW, Larsen PJ.

Obesity (Silver Spring). 2009 Oct 22. [Epub ahead of print]PMID: 19851307 [PubMed - as supplied by publisher]Related articles

Prevalence of loss of function FTO mutations in lean and obese individuals.

Meyre D, Proulx K, Kawagoe-Takaki H, Vatin V, Gutiérrez-Aguilar R, Lyon D, Ma M, Choquet H, Horber F, Van Hul W, Van Gaal L, Balkau B, Visvikis-Siest S, Pattou F, Farooqi IS, Saudek V, O'Rahilly S, Froguel P, Sedgwick B, Yeo GS.

Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833892 [PubMed - as supplied by publisher]Related articles

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.

Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proença C, Bacot F, Balkau B, Belisle A, Borch-Johnsen K, Charpentier G, Dina C, Durand E, Elliott P, Hadjadj S, Järvelin MR, Laitinen J, Lauritzen T, Marre M, Mazur A, Meyre D, Montpetit A, Pisinger C, Posner B, Poulsen P, Pouta A, Prentki M, Ribel-Madsen R, Ruokonen A, Sandbaek A, Serre D, Tichet J, Vaxillaire M, Wojtaszewski JF, Vaag A, Hansen T, Polychronakos C, Pedersen O, Froguel P, Sladek R.

Nat Genet. 2009 Oct;41(10):1110-5. Epub 2009 Sep 6. Erratum in: Nat Genet. 2009 Oct;41(10):1156. PMID: 19734900 [PubMed - indexed for MEDLINE]Related articles

Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits.

Bonnefond A, Vaxillaire M, Labrune Y, Lecoeur C, Chèvre JC, Bouatia-Naji N, Cauchi S, Balkau B, Marre M, Tichet J, Riveline JP, Hadjadj S, Gallois Y, Czernichow S, Hercberg S, Kaakinen M, Wiesner S, Charpentier G, Lévy-Marchal C, Elliott P, Jarvelin MR, Horber F, Dina C, Pedersen O, Sladek R, Meyre D, Froguel P.

Diabetes. 2009 Nov;58(11):2687-97. Epub 2009 Aug 3.PMID: 19651813 [PubMed - in process]Related articles

Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations.

Boissel S, Reish O, Proulx K, Kawagoe-Takaki H, Sedgwick B, Yeo GS, Meyre D, Golzio C, Molinari F, Kadhom N, Etchevers HC, Saudek V, Farooqi IS, Froguel P, Lindahl T, O'Rahilly S, Munnich A, Colleaux L.

Am J Hum Genet. 2009 Jul;85(1):106-11. Epub 2009 Jun 25.PMID: 19559399 [PubMed - indexed for MEDLINE]Related articles

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians.

Traurig M, Mack J, Hanson RL, Ghoussaini M, Meyre D, Knowler WC, Kobes S, Froguel P, Bogardus C, Baier LJ.

Diabetes. 2009 Jul;58(7):1682-9. Epub 2009 Apr 28.PMID: 19401419 [PubMed - indexed for MEDLINE]Related articlesFree article

The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects.

Choquet H, Cavalcanti-Proença C, Lecoeur C, Dina C, Cauchi S, Vaxillaire M, Hadjadj S, Horber F, Potoczna N, Charpentier G, Ruiz J, Hercberg S, Maimaitiming S, Roussel R, Boenhnke M, Jackson AU, Patsch W, Krempler F, Voight BF, Altshuler D, Groop L, Thorleifsson G, Steinthorsdottir V, Stefansson K, Balkau B, Froguel P, Meyre D.

Hum Mol Genet. 2009 Jul 1;18(13):2495-501. Epub 2009 Apr 18.PMID: 19377085 [PubMed - indexed for MEDLINE]Related articles

A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity.

Blakemore AI, Meyre D, Delplanque J, Vatin V, Lecoeur C, Marre M, Tichet J, Balkau B, Froguel P, Walley AJ.

Obesity (Silver Spring). 2009 Aug;17(8):1549-53. Epub 2009 Mar 19.PMID: 19300429 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 is associated with type 2 diabetes in nonobese individuals from Tunisia.

Bouhaha R, Choquet H, Meyre D, Abid Kamoun H, Ennafaa H, Baroudi T, Sassi R, Vaxillaire M, Elgaaied A, Froguel P, Cauchi S.

Pathol Biol (Paris). 2009 Mar 13. [Epub ahead of print]PMID: 19286335 [PubMed - as supplied by publisher]Related articles

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.

Cauchi S, Stutzmann F, Cavalcanti-Proença C, Durand E, Pouta A, Hartikainen AL, Marre M, Vol S, Tammelin T, Laitinen J, Gonzalez-Izquierdo A, Blakemore AI, Elliott P, Meyre D, Balkau B, Järvelin MR, Froguel P.

J Mol Med. 2009 May;87(5):537-46. Epub 2009 Mar 3.PMID: 19255736 [PubMed - indexed for MEDLINE]Related articles

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.

Gueorguiev M, Lecoeur C, Meyre D, Benzinou M, Mein CA, Hinney A, Vatin V, Weill J, Heude B, Hebebrand J, Grossman AB, Korbonits M, Froguel P.

Obesity (Silver Spring). 2009 Apr;17(4):745-54. Epub 2009 Jan 22.PMID: 19165163 [PubMed - indexed for MEDLINE]Related articles

Common genetic variation near MC4R is associated with eating behaviour patterns in European populations.

Stutzmann F, Cauchi S, Durand E, Calvacanti-Proença C, Pigeyre M, Hartikainen AL, Sovio U, Tichet J, Marre M, Weill J, Balkau B, Potoczna N, Laitinen J, Elliott P, Järvelin MR, Horber F, Meyre D, Froguel P.

Int J Obes (Lond). 2009 Mar;33(3):373-8. Epub 2009 Jan 20.PMID: 19153581 [PubMed - in process]Related articles

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.

Meyre D, Delplanque J, Chèvre JC, Lecoeur C, Lobbens S, Gallina S, Durand E, Vatin V, Degraeve F, Proença C, Gaget S, Körner A, Kovacs P, Kiess W, Tichet J, Marre M, Hartikainen AL, Horber F, Potoczna N, Hercberg S, Levy-Marchal C, Pattou F, Heude B, Tauber M, McCarthy MI, Blakemore AI, Montpetit A, Polychronakos C, Weill J, Coin LJ, Asher J, Elliott P, Järvelin MR, Visvikis-Siest S, Balkau B, Sladek R, Balding D, Walley A, Dina C, Froguel P.

Nat Genet. 2009 Feb;41(2):157-9. Epub 2009 Jan 18.PMID: 19151714 [PubMed - indexed for MEDLINE]Related articles

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.

Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De Graeve F, Chèvre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jørgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Lévy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P.

Nat Genet. 2009 Jan;41(1):89-94. Epub 2008 Dec 7.PMID: 19060909 [PubMed - indexed for MEDLINE]Related articles

Association of the ENPP1 K121Q polymorphism with type 2 diabetes and obesity in the Moroccan population.

El Achhab Y, Meyre D, Bouatia-Naji N, Berraho M, Deweirder M, Vatin V, Delplanque J, Serhier Z, Lyoussi B, Nejjari C, Froguel P, Chikri M.

Diabetes Metab. 2009 Feb;35(1):37-42. Epub 2008 Nov 28.PMID: 19046915 [PubMed - indexed for MEDLINE]Related articles

The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population.

Morandi A, Pinelli L, Petrone A, Vatin V, Buzzetti R, Froguel P, Meyre D.

Obesity (Silver Spring). 2009 Jan;17(1):202-6. Epub 2008 Oct 23.PMID: 18948963 [PubMed - indexed for MEDLINE]Related articles

A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature.

Gueorguiev M, Lecoeur C, Benzinou M, Mein CA, Meyre D, Vatin V, Weill J, Heude B, Grossman AB, Froguel P, Korbonits M.

Ann Hum Genet. 2009 Jan;73(1):1-9. Epub 2008 Oct 15.PMID: 18945286 [PubMed - indexed for MEDLINE]Related articles

Effect of ENPP1/PC-1-K121Q and PPARgamma-Pro12Ala polymorphisms on the genetic susceptibility to T2D in the Tunisian population.

Bouhaha R, Meyre D, Kamoun HA, Ennafaa H, Vaillant E, Sassi R, Baroudi T, Vatin V, Froguel P, Elgaaied A, Vaxillaire M.

Diabetes Res Clin Pract. 2008 Sep;81(3):278-83. Epub 2008 Jul 25.PMID: 18657335 [PubMed - indexed for MEDLINE]Related articles

Common nonsynonymous variants in PCSK1 confer risk of obesity.

Benzinou M, Creemers JW, Choquet H, Lobbens S, Dina C, Durand E, Guerardel A, Boutin P, Jouret B, Heude B, Balkau B, Tichet J, Marre M, Potoczna N, Horber F, Le Stunff C, Czernichow S, Sandbaek A, Lauritzen T, Borch-Johnsen K, Andersen G, Kiess W, Körner A, Kovacs P, Jacobson P, Carlsson LM, Walley AJ, Jørgensen T, Hansen T, Pedersen O, Meyre D, Froguel P.

Nat Genet. 2008 Aug;40(8):943-5. Epub 2008 Jul 6.PMID: 18604207 [PubMed - indexed for MEDLINE]Related articles

Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.

Stutzmann F, Tan K, Vatin V, Dina C, Jouret B, Tichet J, Balkau B, Potoczna N, Horber F, O'Rahilly S, Farooqi IS, Froguel P, Meyre D.

Diabetes. 2008 Sep;57(9):2511-8. Epub 2008 Jun 16.PMID: 18559663 [PubMed - indexed for MEDLINE]Related articlesFree article

The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies.

Cauchi S, Nead KT, Choquet H, Horber F, Potoczna N, Balkau B, Marre M, Charpentier G, Froguel P, Meyre D.

BMC Med Genet. 2008 May 22;9:45.PMID: 18498634 [PubMed - indexed for MEDLINE]Related articlesFree article

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.

Cauchi S, Meyre D, Durand E, Proença C, Marre M, Hadjadj S, Choquet H, De Graeve F, Gaget S, Allegaert F, Delplanque J, Permutt MA, Wasson J, Blech I, Charpentier G, Balkau B, Vergnaud AC, Czernichow S, Patsch W, Chikri M, Glaser B, Sladek R, Froguel P.

PLoS One. 2008 May 7;3(5):e2031.PMID: 18461161 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI; Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf Farooqi I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM; KORA, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L; Nurses' Health Study, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK; Diabetes Genetics Initiative, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M; SardiNIA Study, Vogel CI, Wallace C, Waterworth DM, Weedon MN; Wellcome Trust Case Control Consortium, Willer CJ; FUSION, Wraight, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Jacobs KB, Chanock SJ, Hayes RB, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, Mohlke KL.

Nat Genet. 2008 Jun;40(6):768-75. Epub 2008 May 4.PMID: 18454148 [PubMed - indexed for MEDLINE]Related articlesFree article

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.

Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proença C, Marchand M, Hartikainen AL, Sovio U, De Graeve F, Rung J, Vaxillaire M, Tichet J, Marre M, Balkau B, Weill J, Elliott P, Jarvelin MR, Meyre D, Polychronakos C, Dina C, Sladek R, Froguel P.

Science. 2008 May 23;320(5879):1085-8. Epub 2008 May 1.PMID: 18451265 [PubMed - indexed for MEDLINE]Related articlesFree article

Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans.

Wermter AK, Scherag A, Meyre D, Reichwald K, Durand E, Nguyen TT, Koberwitz K, Lichtner P, Meitinger T, Schäfer H, Hinney A, Froguel P, Hebebrand J, Brönner G.

Eur J Hum Genet. 2008 Sep;16(9):1126-34. Epub 2008 Apr 9.PMID: 18398438 [PubMed - indexed for MEDLINE]Related articlesFree article

INS VNTR is not associated with childhood obesity in 1,023 families: a family-based study.

Bouatia-Naji N, De Graeve F, Brönner G, Lecoeur C, Vatin V, Durand E, Lichtner P, Nguyen TT, Heude B, Weill J, Lévy-Marchal C, Hebebrand J, Froguel P, Meyre D.

Obesity (Silver Spring). 2008 Jun;16(6):1471-5. Epub 2008 Apr 3.PMID: 18388898 [PubMed - indexed for MEDLINE]Related articles

Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations.

Benzinou M, Chèvre JC, Ward KJ, Lecoeur C, Dina C, Lobbens S, Durand E, Delplanque J, Horber FF, Heude B, Balkau B, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O, Meyre D, Froguel P.

Hum Mol Genet. 2008 Jul 1;17(13):1916-21. Epub 2008 Mar 28.PMID: 18375449 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association scans identified CTNNBL1 as a novel gene for obesity.

Liu YJ, Liu XG, Wang L, Dina C, Yan H, Liu JF, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Meyre D, Delplanque J, Pei YF, Zhang L, Recker RR, Froguel P, Deng HW.

Hum Mol Genet. 2008 Jun 15;17(12):1803-13. Epub 2008 Mar 5.PMID: 18325910 [PubMed - indexed for MEDLINE]Related articlesFree article

R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population.

Meyre D, Farge M, Lecoeur C, Proenca C, Durand E, Allegaert F, Tichet J, Marre M, Balkau B, Weill J, Delplanque J, Froguel P.

Hum Mol Genet. 2008 Jun 15;17(12):1798-802. Epub 2008 Mar 5.PMID: 18325908 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of TCF7L2 polymorphisms on obesity in European populations.

Cauchi S, Choquet H, Gutiérrez-Aguilar R, Capel F, Grau K, Proença C, Dina C, Duval A, Balkau B, Marre M, Potoczna N, Langin D, Horber F, Sørensen TI, Charpentier G, Meyre D, Froguel P.

Obesity (Silver Spring). 2008 Feb;16(2):476-82.PMID: 18239663 [PubMed - indexed for MEDLINE]Related articles

Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study.

Cauchi S, Proença C, Choquet H, Gaget S, De Graeve F, Marre M, Balkau B, Tichet J, Meyre D, Vaxillaire M, Froguel P; D.E.S.I.R. Study Group.

J Mol Med. 2008 Mar;86(3):341-8. Epub 2008 Jan 22.PMID: 18210030 [PubMed - indexed for MEDLINE]Related articles

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study.

Vaxillaire M, Veslot J, Dina C, Proença C, Cauchi S, Charpentier G, Tichet J, Fumeron F, Marre M, Meyre D, Balkau B, Froguel P; DESIR Study Group.

Diabetes. 2008 Jan;57(1):244-54. Epub 2007 Oct 31.PMID: 17977958 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.

Le Stunff C, Dechartres A, Mariot V, Lotton C, Trainor C, Miraglia Del Giudice E, Meyre D, Bieche I, Laurendeau I, Froguel P, Zelenika D, Fallin D, Lathrop M, Roméo PH, Bougnères P.

Diabetes. 2008 Feb;57(2):494-502. Epub 2007 Oct 31.PMID: 17977952 [PubMed - indexed for MEDLINE]Related articlesFree article

ENPP1 K121Q polymorphism and obesity, hyperglycaemia and type 2 diabetes in the prospective DESIR Study.

Meyre D, Bouatia-Naji N, Vatin V, Veslot J, Samson C, Tichet J, Marre M, Balkau B, Froguel P.

Diabetologia. 2007 Oct;50(10):2090-6. Epub 2007 Aug 18.PMID: 17704904 [PubMed - indexed for MEDLINE]Related articles

Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity.

Ghoussaini M, Vatin V, Lecoeur C, Abkevich V, Younus A, Samson C, Wachter C, Heude B, Tauber M, Tounian P, Hercberg S, Weill J, Levy-Marchal C, Le Stunff C, Bougnères P, Froguel P, Meyre D.

J Clin Endocrinol Metab. 2007 Nov;92(11):4403-9. Epub 2007 Aug 14.PMID: 17698913 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.

Salonen JT, Uimari P, Aalto JM, Pirskanen M, Kaikkonen J, Todorova B, Hyppönen J, Korhonen VP, Asikainen J, Devine C, Tuomainen TP, Luedemann J, Nauck M, Kerner W, Stephens RH, New JP, Ollier WE, Gibson JM, Payton A, Horan MA, Pendleton N, Mahoney W, Meyre D, Delplanque J, Froguel P, Luzzatto O, Yakir B, Darvasi A.

Am J Hum Genet. 2007 Aug;81(2):338-45. Epub 2007 Jun 26.PMID: 17668382 [PubMed - indexed for MEDLINE]Related articlesFree article

Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.

Bouatia-Naji N, Vatin V, Lecoeur C, Heude B, Proença C, Veslot J, Jouret B, Tichet J, Charpentier G, Marre M, Balkau B, Froguel P, Meyre D.

BMC Med Genet. 2007 Jul 7;8:44.PMID: 17617923 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 rs7903146 variant does not associate with smallness for gestational age in the French population.

Cauchi S, Meyre D, Choquet H, Deghmoun S, Durand E, Gaget S, Lecoeur C, Froguel P, Levy-Marchal C.

BMC Med Genet. 2007 Jun 25;8:37.PMID: 17593304 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene.

Stutzmann F, Vatin V, Cauchi S, Morandi A, Jouret B, Landt O, Tounian P, Levy-Marchal C, Buzzetti R, Pinelli L, Balkau B, Horber F, Bougnères P, Froguel P, Meyre D.

Hum Mol Genet. 2007 Aug 1;16(15):1837-44. Epub 2007 May 21.PMID: 17519222 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in FTO contributes to childhood obesity and severe adult obesity.

Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P, Carlsson LM, Kiess W, Vatin V, Lecoeur C, Delplanque J, Vaillant E, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Bougnères P, Kovacs P, Marre M, Balkau B, Cauchi S, Chèvre JC, Froguel P.

Nat Genet. 2007 Jun;39(6):724-6. Epub 2007 May 13.PMID: 17496892 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis.

Cauchi S, El Achhab Y, Choquet H, Dina C, Krempler F, Weitgasser R, Nejjari C, Patsch W, Chikri M, Meyre D, Froguel P.

J Mol Med. 2007 Jul;85(7):777-82. Epub 2007 May 3.PMID: 17476472 [PubMed - indexed for MEDLINE]Related articles

A genome-wide association study identifies novel risk loci for type 2 diabetes.

Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P.

Nature. 2007 Feb 22;445(7130):881-5. Epub 2007 Feb 11.PMID: 17293876 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects.

Siddiq A, Gueorguiev M, Samson C, Hercberg S, Heude B, Levy-Marchal C, Jouret B, Weill J, Meyre D, Walley A, Froguel P.

Diabetologia. 2007 Mar;50(3):574-84. Epub 2007 Jan 18.PMID: 17235527 [PubMed - indexed for MEDLINE]Related articles

Comment on "A common genetic variant is associated with adult and childhood obesity".

Dina C, Meyre D, Samson C, Tichet J, Marre M, Jouret B, Charles MA, Balkau B, Froguel P.

Science. 2007 Jan 12;315(5809):187; author reply 187.PMID: 17218508 [PubMed - indexed for MEDLINE]Related articlesFree article

No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases.

Bell CG, Meyre D, Petretto E, Levy-Marchal C, Hercberg S, Charles MA, Boyle C, Weill J, Tauber M, Mein CA, Aitman TJ, Froguel P, Walley AJ.

Eur J Hum Genet. 2007 Mar;15(3):320-7. Epub 2006 Dec 13.PMID: 17164796 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies.

Vasseur F, Meyre D, Froguel P.

Expert Rev Mol Med. 2006 Nov 20;8(27):1-12. Review.PMID: 17112391 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study.

Cauchi S, Meyre D, Choquet H, Dina C, Born C, Marre M, Balkau B, Froguel P; DESIR Study Group.

Diabetes. 2006 Nov;55(11):3189-92. Erratum in: Diabetes. 2006 Dec;55(12):3635. PMID: 17065361 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.

Cauchi S, Meyre D, Dina C, Choquet H, Samson C, Gallina S, Balkau B, Charpentier G, Pattou F, Stetsyuk V, Scharfmann R, Staels B, Frühbeck G, Froguel P.

Diabetes. 2006 Oct;55(10):2903-8.PMID: 17003360 [PubMed - indexed for MEDLINE]Related articlesFree article