PubMed

KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803.

Ogino S, Meyerhardt JA, Irahara N, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Schaefer P, Whittom R, Hantel A, Benson AB 3rd, Goldberg RM, Bertagnolli MM, Fuchs CS; for the Cancer and Leukemia Group B, North Central Cancer Treatment Group, Canadian Cancer Society Research Institute, Southwest Oncology Group.

Clin Cancer Res. 2009 Nov 24. [Epub ahead of print]PMID: 19934290 [PubMed - as supplied by publisher]

Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study.

Zhu AX, Meyerhardt JA, Blaszkowsky LS, Kambadakone AR, Muzikansky A, Zheng H, Clark JW, Abrams TA, Chan JA, Enzinger PC, Bhargava P, Kwak EL, Allen JN, Jain SR, Stuart K, Horgan K, Sheehan S, Fuchs CS, Ryan DP, Sahani DV.

Lancet Oncol. 2009 Nov 19. [Epub ahead of print]PMID: 19932054 [PubMed - as supplied by publisher]

Getting knit-PI3Ky: PIK3CA mutation status to direct multimodality therapy?

Myers AP, Meyerhardt JA, Cantley LC.

Clin Cancer Res. 2009 Nov 15;15(22):6748-50. Epub 2009 Nov 10.PMID: 19903790 [PubMed - in process]Related articles

Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.

Ogino S, Nosho K, Irahara N, Meyerhardt JA, Baba Y, Shima K, Glickman JN, Ferrone CR, Mino-Kenudson M, Tanaka N, Dranoff G, Giovannucci EL, Fuchs CS.

Clin Cancer Res. 2009 Oct 15;15(20):6412-20. Epub 2009 Oct 13.PMID: 19825961 [PubMed - in process]Related articles

Negative Lymph Node Count Is Associated With Survival of Colorectal Cancer Patients, Independent of Tumoral Molecular Alterations and Lymphocytic Reaction.

Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Mino-Kenudson M, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Am J Gastroenterol. 2009 Oct 6. [Epub ahead of print]PMID: 19809407 [PubMed - as supplied by publisher]Related articles

Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.

Kure S, Nosho K, Baba Y, Irahara N, Shima K, Ng K, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.

Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72. Epub 2009 Sep 29.PMID: 19789368 [PubMed - in process]Related articles

p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.

Ogino S, Nosho K, Shima K, Baba Y, Irahara N, Kirkner GJ, Hazra A, De Vivo I, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2513-21. Epub 2009 Sep 1.PMID: 19723919 [PubMed - in process]Related articles

Interaction of molecular markers and physical activity on mortality in patients with colon cancer.

Meyerhardt JA, Ogino S, Kirkner GJ, Chan AT, Wolpin B, Ng K, Nosho K, Shima K, Giovannucci EL, Loda M, Fuchs CS.

Clin Cancer Res. 2009 Sep 15;15(18):5931-6. Epub 2009 Sep 1.PMID: 19723652 [PubMed - in process]Related articles

Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.

Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Meyerhardt JA, Fuchs CS.

J Clin Oncol. 2009 Sep 20;27(27):4591-8. Epub 2009 Aug 24.PMID: 19704056 [PubMed - indexed for MEDLINE]Related articles

Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer.

Ng K, Wolpin BM, Meyerhardt JA, Wu K, Chan AT, Hollis BW, Giovannucci EL, Stampfer MJ, Willett WC, Fuchs CS.

Br J Cancer. 2009 Sep 15;101(6):916-23. Epub 2009 Aug 18.PMID: 19690551 [PubMed - indexed for MEDLINE]Related articles

A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.

Nosho K, Kure S, Irahara N, Shima K, Baba Y, Spiegelman D, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S.

Gastroenterology. 2009 Nov;137(5):1609-20.e1-3. Epub 2009 Aug 14.PMID: 19686742 [PubMed - in process]Related articles

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer.

Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH, Shivdasani RA.

Br J Cancer. 2009 Aug 4;101(3):465-72. Epub 2009 Jul 14.PMID: 19603024 [PubMed - indexed for MEDLINE]Related articles

Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.

Baba Y, Nosho K, Shima K, Freed E, Irahara N, Philips J, Meyerhardt JA, Hornick JL, Shivdasani RA, Fuchs CS, Ogino S.

Clin Cancer Res. 2009 Jul 15;15(14):4665-73. Epub 2009 Jul 7.PMID: 19584150 [PubMed - indexed for MEDLINE]Related articles

A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.

Ogino S, Nosho K, Irahara N, Kure S, Shima K, Baba Y, Toyoda S, Chen L, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Clin Cancer Res. 2009 Jul 1;15(13):4431-8. Epub 2009 Jun 23.PMID: 19549773 [PubMed - indexed for MEDLINE]Related articles

A cohort study of p27 localization in colon cancer, body mass index, and patient survival.

Ogino S, Shima K, Nosho K, Irahara N, Baba Y, Wolpin BM, Giovannucci EL, Meyerhardt JA, Fuchs CS.

Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.PMID: 19505918 [PubMed - indexed for MEDLINE]Related articles

Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer.

Enzinger PC, Ryan DP, Clark JW, Muzikansky A, Earle CC, Kulke MH, Meyerhardt JA, Blaszkowsky LS, Zhu AX, Fidias P, Vincitore MM, Mayer RJ, Fuchs CS.

Ann Oncol. 2009 Mar;20(3):475-80. Epub 2009 Jan 12.PMID: 19139178 [PubMed - indexed for MEDLINE]Related articles

O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.

Kulke MH, Hornick JL, Frauenhoffer C, Hooshmand S, Ryan DP, Enzinger PC, Meyerhardt JA, Clark JW, Stuart K, Fuchs CS, Redston MS.

Clin Cancer Res. 2009 Jan 1;15(1):338-45.PMID: 19118063 [PubMed - indexed for MEDLINE]Related articles

Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.

Fuchs CS, Goldberg RM, Sargent DJ, Meyerhardt JA, Wolpin BM, Green EM, Pitot HC, Pollak M.

Clin Cancer Res. 2008 Dec 15;14(24):8263-9. Epub 2008 Dec 10.PMID: 19073970 [PubMed - indexed for MEDLINE]Related articles

Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer.

Wolpin BM, Meyerhardt JA, Chan AT, Ng K, Chan JA, Wu K, Pollak MN, Giovannucci EL, Fuchs CS.

J Clin Oncol. 2009 Jan 10;27(2):176-85. Epub 2008 Dec 8.PMID: 19064975 [PubMed - indexed for MEDLINE]Related articles

Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.

Wolpin BM, Hezel AF, Abrams T, Blaszkowsky LS, Meyerhardt JA, Chan JA, Enzinger PC, Allen B, Clark JW, Ryan DP, Fuchs CS.

J Clin Oncol. 2009 Jan 10;27(2):193-8. Epub 2008 Dec 1.PMID: 19047305 [PubMed - indexed for MEDLINE]Related articles

Cohort study of fatty acid synthase expression and patient survival in colon cancer.

Ogino S, Nosho K, Meyerhardt JA, Kirkner GJ, Chan AT, Kawasaki T, Giovannucci EL, Loda M, Fuchs CS.

J Clin Oncol. 2008 Dec 10;26(35):5713-20. Epub 2008 Oct 27.PMID: 18955444 [PubMed - indexed for MEDLINE]Related articles

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.

Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Meyerhardt JA, Loda M, Giovannucci EL, Fuchs CS.

Gut. 2009 Jan;58(1):90-6. Epub 2008 Oct 2.PMID: 18832519 [PubMed - indexed for MEDLINE]Related articles

DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.

Bracht LK, Wen P, Meyerhardt JA, Kulke MH, Hornick JL, Redston M, LaFrankie DC, Black PM, Kesari S, Norden A, Drappatz J.

J Clin Oncol. 2008 Oct 10;26(29):4843-4. Epub 2008 Sep 8. No abstract available. PMID: 18779600 [PubMed - indexed for MEDLINE]Related articles

Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803.

Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Nelson H, Whittom R, Hantel A, Thomas J, Fuchs CS; Cancer and Leukemia Group B 89803.

J Clin Oncol. 2008 Sep 1;26(25):4109-15.PMID: 18757324 [PubMed - indexed for MEDLINE]Related articlesFree article

Prediagnostic plasma folate and the risk of death in patients with colorectal cancer.

Wolpin BM, Wei EK, Ng K, Meyerhardt JA, Chan JA, Selhub J, Giovannucci EL, Fuchs CS.

J Clin Oncol. 2008 Jul 1;26(19):3222-8.PMID: 18591557 [PubMed - indexed for MEDLINE]Related articles

Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer.

Ng K, Meyerhardt JA, Wu K, Feskanich D, Hollis BW, Giovannucci EL, Fuchs CS.

J Clin Oncol. 2008 Jun 20;26(18):2984-91.PMID: 18565885 [PubMed - indexed for MEDLINE]Related articles

Association of family history with cancer recurrence and survival among patients with stage III colon cancer.

Chan JA, Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Thomas J, Schaefer P, Whittom R, Hantel A, Goldberg RM, Warren RS, Bertagnolli M, Fuchs CS.

JAMA. 2008 Jun 4;299(21):2515-23.PMID: 18523220 [PubMed - indexed for MEDLINE]Related articlesFree article

Family history and survival after colorectal cancer diagnosis.

Bass AJ, Meyerhardt JA, Chan JA, Giovannucci EL, Fuchs CS.

Cancer. 2008 Mar 15;112(6):1222-9.PMID: 18219663 [PubMed - indexed for MEDLINE]Related articlesFree article

CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.

Kawasaki T, Ohnishi M, Nosho K, Suemoto Y, Kirkner GJ, Meyerhardt JA, Fuchs CS, Ogino S.

Mod Pathol. 2008 Mar;21(3):245-55. Epub 2008 Jan 18.PMID: 18204436 [PubMed - indexed for MEDLINE]Related articlesFree article

Aspirin dose and duration of use and risk of colorectal cancer in men.

Chan AT, Giovannucci EL, Meyerhardt JA, Schernhammer ES, Wu K, Fuchs CS.

Gastroenterology. 2008 Jan;134(1):21-8. Epub 2007 Sep 26.PMID: 18005960 [PubMed - indexed for MEDLINE]Related articlesFree article

Capecitabine plus erlotinib in gemcitabine-refractory advanced pancreatic cancer.

Kulke MH, Blaszkowsky LS, Ryan DP, Clark JW, Meyerhardt JA, Zhu AX, Enzinger PC, Kwak EL, Muzikansky A, Lawrence C, Fuchs CS.

J Clin Oncol. 2007 Oct 20;25(30):4787-92.PMID: 17947726 [PubMed - indexed for MEDLINE]Related articles

Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.

Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Dehari R, Meyerhardt JA, Fuchs CS, Ogino S.

Neoplasia. 2007 Jul;9(7):569-77.PMID: 17710160 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer.

Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Hu FB, Mayer RJ, Nelson H, Whittom R, Hantel A, Thomas J, Fuchs CS.

JAMA. 2007 Aug 15;298(7):754-64.PMID: 17699009 [PubMed - indexed for MEDLINE]Related articlesFree article

MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.

Ogino S, Hazra A, Tranah GJ, Kirkner GJ, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Meyerhardt JA, Hunter DJ, Fuchs CS.

Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.PMID: 17621591 [PubMed - indexed for MEDLINE]Related articlesFree article

Adjuvant and neoadjuvant approaches in gastric cancer.

Ng K, Meyerhardt JA, Fuchs CS.

Cancer J. 2007 May-Jun;13(3):168-74. Review.PMID: 17620766 [PubMed - indexed for MEDLINE]Related articles

Phase-II study of gemcitabine and cisplatin in patients with metastatic biliary and gallbladder cancer.

Meyerhardt JA, Zhu AX, Stuart K, Ryan DP, Blaszkowsky L, Lehman N, Earle CC, Kulke MH, Bhargava P, Fuchs CS.

Dig Dis Sci. 2008 Feb;53(2):564-70. Epub 2007 Jun 29.PMID: 17597402 [PubMed - indexed for MEDLINE]Related articles

Phase 2 study of cetuximab in patients with advanced hepatocellular carcinoma.

Zhu AX, Stuart K, Blaszkowsky LS, Muzikansky A, Reitberg DP, Clark JW, Enzinger PC, Bhargava P, Meyerhardt JA, Horgan K, Fuchs CS, Ryan DP.

Cancer. 2007 Aug 1;110(3):581-9.PMID: 17583545 [PubMed - indexed for MEDLINE]Related articlesFree article

Adjuvant treatment of colorectal cancer.

Wolpin BM, Meyerhardt JA, Mamon HJ, Mayer RJ.

CA Cancer J Clin. 2007 May-Jun;57(3):168-85. Review.PMID: 17507442 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase II study of FOLFOX, bevacizumab and erlotinib as first-line therapy for patients with metastatic colorectal cancer.

Meyerhardt JA, Stuart K, Fuchs CS, Zhu AX, Earle CC, Bhargava P, Blaszkowsky L, Enzinger P, Mayer RJ, Battu S, Lawrence C, Ryan DP.

Ann Oncol. 2007 Jul;18(7):1185-9. Epub 2007 May 4.PMID: 17483115 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of hospital volume on recurrence and survival after surgery for gastric cancer.

Enzinger PC, Benedetti JK, Meyerhardt JA, McCoy S, Hundahl SA, Macdonald JS, Fuchs CS.

Ann Surg. 2007 Mar;245(3):426-34.PMID: 17435550 [PubMed - indexed for MEDLINE]Related articlesFree article

CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.

Ogino S, Meyerhardt JA, Kawasaki T, Clark JW, Ryan DP, Kulke MH, Enzinger PC, Wolpin BM, Loda M, Fuchs CS.

Virchows Arch. 2007 May;450(5):529-37. Epub 2007 Mar 20.PMID: 17372756 [PubMed - indexed for MEDLINE]Related articles

Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.

Ogino S, Kawasaki T, Kirkner GJ, Suemoto Y, Meyerhardt JA, Fuchs CS.

Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5.PMID: 17339237 [PubMed - indexed for MEDLINE]Related articles

Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer.

Meyerhardt JA, Clark JW, Supko JG, Eder JP, Ogino S, Stewart CF, D'Amato F, Dancey J, Enzinger PC, Zhu AX, Ryan DP, Earle CC, Mayer RJ, Michelini A, Kinsella K, Fuchs CS.

Cancer Chemother Pharmacol. 2007 Oct;60(5):661-70. Epub 2007 Jan 11.PMID: 17216531 [PubMed - indexed for MEDLINE]Related articles

Hormone replacement therapy and survival after colorectal cancer diagnosis.

Chan JA, Meyerhardt JA, Chan AT, Giovannucci EL, Colditz GA, Fuchs CS.

J Clin Oncol. 2006 Dec 20;24(36):5680-6.PMID: 17179103 [PubMed - indexed for MEDLINE]Related articles

Phase I study of gefitinib plus FOLFIRI in previously untreated patients with metastatic colorectal cancer.

Wolpin BM, Clark JW, Meyerhardt JA, Earle CC, Ryan DP, Enzinger PC, Zhu AX, Blaszkowsky L, Battu S, Fuchs CS.

Clin Colorectal Cancer. 2006 Sep;6(3):208-13.PMID: 17026790 [PubMed - indexed for MEDLINE]Related articles

Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors.

Kulke MH, Bergsland EK, Ryan DP, Enzinger PC, Lynch TJ, Zhu AX, Meyerhardt JA, Heymach JV, Fogler WE, Sidor C, Michelini A, Kinsella K, Venook AP, Fuchs CS.

J Clin Oncol. 2006 Aug 1;24(22):3555-61.PMID: 16877721 [PubMed - indexed for MEDLINE]Related articles

Physical activity and survival after colorectal cancer diagnosis.

Meyerhardt JA, Giovannucci EL, Holmes MD, Chan AT, Chan JA, Colditz GA, Fuchs CS.

J Clin Oncol. 2006 Aug 1;24(22):3527-34. Epub 2006 Jul 5.PMID: 16822844 [PubMed - indexed for MEDLINE]Related articles

Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803.

Meyerhardt JA, Heseltine D, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Thomas J, Nelson H, Whittom R, Hantel A, Schilsky RL, Fuchs CS.

J Clin Oncol. 2006 Aug 1;24(22):3535-41. Epub 2006 Jul 5.PMID: 16822843 [PubMed - indexed for MEDLINE]Related articles

Efficacy of cetuximab after treatment with oral epidermal growth factor receptor tyrosine kinase inhibitor-based chemotherapy in metastatic colorectal cancer.

Meyerhardt JA, Heseltine D, Ogino S, Clark JW, Enzinger PC, Ryan DP, Earle CC, Zhu AX, Fuchs CS.

Clin Colorectal Cancer. 2006 May;6(1):59-65.PMID: 16796793 [PubMed - indexed for MEDLINE]Related articles

Phase I and pharmacokinetic study of S-1 administered for 14 days in a 21-day cycle in patients with advanced upper gastrointestinal cancer.

Zhu AX, Clark JW, Ryan DP, Meyerhardt JA, Enzinger PC, Earle CC, Fuchs CS, Regan E, Anbe H, Houghton M, Zhang J, Urrea P, Kulke MH.

Cancer Chemother Pharmacol. 2007 Feb;59(3):285-93. Epub 2006 Jun 20.PMID: 16786333 [PubMed - indexed for MEDLINE]Related articles