PubMed

Heightened Endoplasmic Reticulum Stress in COPD Lungs: The Role of Nrf2-Regulated Proteasomal Activity.

Malhotra D, Thimmulappa R, Vij N, Navas-Acien A, Sussan T, Merali S, Zhang L, Kelsen SG, Myers A, Wise R, Tuder R, Biswal S.

Am J Respir Crit Care Med. 2009 Oct 1. [Epub ahead of print]PMID: 19797762 [PubMed - as supplied by publisher]Related articles

Functional analysis of the -2548G/A leptin gene polymorphism in breast cancer cells.

Terrasi M, Fiorio E, Mercanti A, Koda M, Moncada CA, Sulkowski S, Merali S, Russo A, Surmacz E.

Int J Cancer. 2009 Sep 1;125(5):1038-44.PMID: 19408304 [PubMed - indexed for MEDLINE]Related articles

Supervision: what the foundation year doctor needs to know.

George S, Abdel-Maksoud MB, Merali S.

Br J Hosp Med (Lond). 2009 Feb;70(2):M23-5. No abstract available. PMID: 19294817 [PubMed - indexed for MEDLINE]Related articles

Proteomic analysis of oxidative stress-responsive proteins in human pneumocytes: insight into the regulation of DJ-1 expression.

Duan X, Kelsen SG, Merali S.

J Proteome Res. 2008 Nov;7(11):4955-61. Epub 2008 Sep 26.PMID: 18817430 [PubMed - indexed for MEDLINE]Related articles

Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals.

Boden G, Duan X, Homko C, Molina EJ, Song W, Perez O, Cheung P, Merali S.

Diabetes. 2008 Sep;57(9):2438-44. Epub 2008 Jun 20.PMID: 18567819 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism and tissue specificity of nicotine-mediated lung S-adenosylmethionine reduction.

Moncada CA, Clarkson A, Perez-Leal O, Merali S.

J Biol Chem. 2008 Mar 21;283(12):7690-6. Epub 2008 Jan 7.PMID: 18180293 [PubMed - indexed for MEDLINE]Related articlesFree article

S-adenosylmethionine levels in the diagnosis of Pneumocystis carinii pneumonia in patients with HIV infection.

Skelly MJ, Holzman RS, Merali S.

Clin Infect Dis. 2008 Feb 1;46(3):467-71.PMID: 18177224 [PubMed - indexed for MEDLINE]Related articles

Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences.

Kramer DL, Diegelman P, Jell J, Vujcic S, Merali S, Porter CW.

J Biol Chem. 2008 Feb 15;283(7):4241-51. Epub 2007 Dec 18.PMID: 18089555 [PubMed - indexed for MEDLINE]Related articlesFree article

Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach.

Kelsen SG, Duan X, Ji R, Perez O, Liu C, Merali S.

Am J Respir Cell Mol Biol. 2008 May;38(5):541-50. Epub 2007 Dec 13.PMID: 18079489 [PubMed - indexed for MEDLINE]Related articlesFree article

S-adenosylmethionine as a biomarker for the early detection of lung cancer.

Greenberg AK, Rimal B, Felner K, Zafar S, Hung J, Eylers E, Phalan B, Zhang M, Goldberg JD, Crawford B, Rom WN, Naidich D, Merali S.

Chest. 2007 Oct;132(4):1247-52.PMID: 17934114 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyamine-mediated apoptosis of alveolar macrophages during Pneumocystis pneumonia.

Lasbury ME, Merali S, Durant PJ, Tschang D, Ray CA, Lee CH.

J Biol Chem. 2007 Apr 13;282(15):11009-20. Epub 2007 Feb 21.PMID: 17314093 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA.

Jell J, Merali S, Hensen ML, Mazurchuk R, Spernyak JA, Diegelman P, Kisiel ND, Barrero C, Deeb KK, Alhonen L, Patel MS, Porter CW.

J Biol Chem. 2007 Mar 16;282(11):8404-13. Epub 2006 Dec 21.PMID: 17189273 [PubMed - indexed for MEDLINE]Related articlesFree article

Ubiquinone synthesis and its regulation in Pneumocystis carinii.

Kaneshiro ES, Basselin M, Merali S, Kayser O.

J Eukaryot Microbiol. 2006 Nov-Dec;53(6):435-44.PMID: 17123407 [PubMed - indexed for MEDLINE]Related articles

Effect of nicotine on lung S-adenosylmethionine and development of Pneumocystis pneumonia.

Shivji M, Burger S, Moncada CA, Clarkson AB Jr, Merali S.

J Biol Chem. 2005 Apr 15;280(15):15219-28. Epub 2005 Jan 24.PMID: 15668255 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term outcome of isolated coronary artery bypass surgery in patients with severe left ventricular dysfunction.

Appoo J, Norris C, Merali S, Graham MM, Koshal A, Knudtson ML, Ghali WA.

Circulation. 2004 Sep 14;110(11 Suppl 1):II13-7.PMID: 15364831 [PubMed - indexed for MEDLINE]Related articlesFree article

S-adenosylmethionine and Pneumocystis.

Merali S, Clarkson AB Jr.

FEMS Microbiol Lett. 2004 Aug 15;237(2):179-86. Review.PMID: 15321660 [PubMed - indexed for MEDLINE]Related articles

Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice.

Kee K, Foster BA, Merali S, Kramer DL, Hensen ML, Diegelman P, Kisiel N, Vujcic S, Mazurchuk RV, Porter CW.

J Biol Chem. 2004 Sep 17;279(38):40076-83. Epub 2004 Jul 13.PMID: 15252047 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.

Kee K, Vujcic S, Merali S, Diegelman P, Kisiel N, Powell CT, Kramer DL, Porter CW.

J Biol Chem. 2004 Jun 25;279(26):27050-8. Epub 2004 Apr 19.PMID: 15096507 [PubMed - indexed for MEDLINE]Related articlesFree article

Summary of pneumocystis research presented at the 8th International Workshop on Opportunistic Protists.

Limper AH, Merali S.

J Eukaryot Microbiol. 2003;50 Suppl:602-4. No abstract available. PMID: 14736178 [PubMed - indexed for MEDLINE]Related articles

Oxidosqualene cyclase inhibitors as antimicrobial agents.

Hinshaw JC, Suh DY, Garnier P, Buckner FS, Eastman RT, Matsuda SP, Joubert BM, Coppens I, Joiner KA, Merali S, Nash TE, Prestwich GD.

J Med Chem. 2003 Sep 25;46(20):4240-3.PMID: 13678402 [PubMed - indexed for MEDLINE]Related articles

S-adenosylmethionine concentrations in diagnosis of Pneumocystis carinii pneumonia.

Skelly M, Hoffman J, Fabbri M, Holzman RS, Clarkson AB Jr, Merali S.

Lancet. 2003 Apr 12;361(9365):1267-8.PMID: 12699956 [PubMed - indexed for MEDLINE]Related articles

Antiviral activity of characterized extracts from echinacea spp. (Heliantheae: Asteraceae) against herpes simplex virus (HSV-I).

Binns SE, Hudson J, Merali S, Arnason JT.

Planta Med. 2002 Sep;68(9):780-3.PMID: 12357386 [PubMed - indexed for MEDLINE]Related articles

The enteric parasite Entamoeba uses an autocrine catecholamine system during differentiation into the infectious cyst stage.

Coppi A, Merali S, Eichinger D.

J Biol Chem. 2002 Mar 8;277(10):8083-90. Epub 2002 Jan 4.PMID: 11779874 [PubMed - indexed for MEDLINE]Related articlesFree article

Action of deferoxamine against Pneumocystis carinii.

Clarkson AB Jr, Turkel-Parrella D, Williams JH, Chen LC, Gordon T, Merali S.

Antimicrob Agents Chemother. 2001 Dec;45(12):3560-5.PMID: 11709340 [PubMed - indexed for MEDLINE]Related articlesFree article

Pneumocystis carinii infection presenting as an intra-abdominal cystic mass in a child with acquired immunodeficiency syndrome.

Hagmann S, Merali S, Sitnitskaya Y, Fefferman N, Pollack H.

Clin Infect Dis. 2001 Oct 15;33(8):1424-6. Epub 2001 Sep 17.PMID: 11565084 [PubMed - indexed for MEDLINE]Related articles

S-adenosylmethionine and Pneumocystis carinii.

Merali S, Vargas D, Franklin M, Clarkson AB Jr.

J Biol Chem. 2000 May 19;275(20):14958-63.PMID: 10809741 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of a bis-benzyl polyamine analogue on Pneumocystis carinii.

Merali S, Saric M, Chin K, Clarkson AB Jr.

Antimicrob Agents Chemother. 2000 Feb;44(2):337-43.PMID: 10639359 [PubMed - indexed for MEDLINE]Related articlesFree article

Pneumocystis carinii polyamine catabolism.

Merali S.

J Biol Chem. 1999 Jul 23;274(30):21017-22.PMID: 10409651 [PubMed - indexed for MEDLINE]Related articlesFree article

Continuous axenic cultivation of Pneumocystis carinii.

Merali S, Frevert U, Williams JH, Chin K, Bryan R, Clarkson AB Jr.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2402-7.PMID: 10051654 [PubMed - indexed for MEDLINE]Related articlesFree article

Continuous infusion of DL-alpha-difluoromethylornithine and improved efficacy against a rat model of Pneumocystis carinii pneumonia.

Chin K, Merali S, Sarić M, Clarkson AB Jr.

Antimicrob Agents Chemother. 1996 Oct;40(10):2318-20.PMID: 8891137 [PubMed - indexed for MEDLINE]Related articlesFree article

Subpopulations of Pneumocystis carinii separated by a Percoll gradient.

Chin K, Merali S, Shaw MM, Bartlett MS, Clarkson AB Jr.

J Eukaryot Microbiol. 1996 Sep-Oct;43(5):53S. No abstract available. PMID: 8822855 [PubMed - indexed for MEDLINE]Related articles

Clinically achievable plasma deferoxamine concentrations eliminate Pneumocystis carinii trophozoites in a rat model.

Merali S, Chin K, Grady RW, Clarkson AB Jr.

J Eukaryot Microbiol. 1996 Sep-Oct;43(5):52S. No abstract available. PMID: 8822854 [PubMed - indexed for MEDLINE]Related articles

Trophozoite elimination in a rat model of Pneumocystis carinii pneumonia by clinically achievable plasma deferoxamine concentrations.

Merali S, Chin K, Grady RW, Clarkson AB Jr.

Antimicrob Agents Chemother. 1996 May;40(5):1298-300.PMID: 8723489 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-alpha-difluoromethylornithine.

Merali S, Clarkson AB Jr.

Antimicrob Agents Chemother. 1996 Apr;40(4):973-8.PMID: 8849262 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyamine analysis using N-hydroxysuccinimidyl-6-aminoquinoyl carbamate for pre-column derivatization.

Merali S, Clarkson AB Jr.

J Chromatogr B Biomed Appl. 1996 Jan 26;675(2):321-6.PMID: 8852721 [PubMed - indexed for MEDLINE]Related articles

Clinically achievable plasma deferoxamine concentrations are therapeutic in a rat model of Pneumocystis carinii pneumonia.

Merali S, Chin K, Del Angel L, Grady RW, Armstrong M, Clarkson AB Jr.

Antimicrob Agents Chemother. 1995 Sep;39(9):2023-6.PMID: 8540710 [PubMed - indexed for MEDLINE]Related articlesFree article

Response of rat model of Pneumocystis carinii pneumonia to continuous infusion of deferoxamine.

Merali S, Chin K, Grady RW, Weissberger L, Clarkson AB Jr.

Antimicrob Agents Chemother. 1995 Jul;39(7):1442-4.PMID: 7492082 [PubMed - indexed for MEDLINE]Related articlesFree article

p-Aminobenzoic acid transport by normal and Plasmodium falciparum-infected erythrocytes.

Zhang Y, Merali S, Meshnick SR.

Mol Biochem Parasitol. 1992 Jun;52(2):185-94.PMID: 1620158 [PubMed - indexed for MEDLINE]Related articles

Susceptibility of Pneumocystis carinii to artemisinin in vitro.

Merali S, Meshnick SR.

Antimicrob Agents Chemother. 1991 Jun;35(6):1225-7.PMID: 1929266 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of Pneumocystis carinii dihydropteroate synthetase by sulfa drugs.

Merali S, Zhang Y, Sloan D, Meshnick S.

Antimicrob Agents Chemother. 1990 Jun;34(6):1075-8.PMID: 2203302 [PubMed - indexed for MEDLINE]Related articlesFree article