PubMed

Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis.

Husain M, Meggs LG, Vashistha H, Simoes S, Griffiths KO, Kumar D, Mikulak J, Mathieson PW, Saleem MA, Del Valle L, Pina-Oviedo S, Wang JY, Seshan SV, Malhotra A, Reiss K, Singhal PC.

J Biol Chem. 2009 Jun 12;284(24):16648-58. Epub 2009 Apr 21.PMID: 19383602 [PubMed - indexed for MEDLINE]Related articles

Inhibition of p66ShcA redox activity in cardiac muscle cells attenuates hyperglycemia-induced oxidative stress and apoptosis.

Malhotra A, Vashistha H, Yadav VS, Dube MG, Kalra SP, Abdellatif M, Meggs LG.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H380-8. Epub 2008 Dec 5.PMID: 19060130 [PubMed - indexed for MEDLINE]Related articles

Overexpression of Gsalpha compensates for myocyte loss in diabetic cardiomyopathy.

Malhotra A, Kang BP, Vashistha H, Yadav VS, Meggs LG.

Can J Physiol Pharmacol. 2008 Mar;86(3):122-30.PMID: 18418439 [PubMed - indexed for MEDLINE]Related articles

Inhibition of wild-type p66ShcA in mesangial cells prevents glycooxidant-dependent FOXO3a regulation and promotes the survival phenotype.

Chintapalli J, Yang S, Opawumi D, Goyal SR, Shamsuddin N, Malhotra A, Reiss K, Meggs LG.

Am J Physiol Renal Physiol. 2007 Feb;292(2):F523-30. Epub 2006 Oct 31.PMID: 17077388 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated IGF-1R inhibits hyperglycemia-induced DNA damage and promotes DNA repair by homologous recombination.

Yang S, Chintapalli J, Sodagum L, Baskin S, Malhotra A, Reiss K, Meggs LG.

Am J Physiol Renal Physiol. 2005 Nov;289(5):F1144-52. Epub 2005 Jun 14.PMID: 15956778 [PubMed - indexed for MEDLINE]Related articlesFree article

PKC-{epsilon}-dependent survival signals in diabetic hearts.

Malhotra A, Begley R, Kang BP, Rana I, Liu J, Yang G, Mochly-Rosen D, Meggs LG.

Am J Physiol Heart Circ Physiol. 2005 Oct;289(4):H1343-50. Epub 2005 May 13.PMID: 15894568 [PubMed - indexed for MEDLINE]Related articlesFree article

PKCepsilon inhibits the hyperglycemia-induced apoptosis signal in adult rat ventricular myocytes.

Malhotra A, Kang BP, Hashmi S, Meggs LG.

Mol Cell Biochem. 2005 Jan;268(1-2):169-73.PMID: 15724450 [PubMed - indexed for MEDLINE]Related articles

Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart.

Liu J, Masurekar MR, Vatner DE, Jyothirmayi GN, Regan TJ, Vatner SF, Meggs LG, Malhotra A.

Am J Physiol Heart Circ Physiol. 2003 Dec;285(6):H2587-91. Epub 2003 Aug 28.PMID: 12946933 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-1 inhibits the mitochondrial apoptosis program in mesangial cells exposed to high glucose.

Kang BP, Urbonas A, Baddoo A, Baskin S, Malhotra A, Meggs LG.

Am J Physiol Renal Physiol. 2003 Nov;285(5):F1013-24. Epub 2003 Jul 22.PMID: 12876069 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose promotes mesangial cell apoptosis by oxidant-dependent mechanism.

Kang BP, Frencher S, Reddy V, Kessler A, Malhotra A, Meggs LG.

Am J Physiol Renal Physiol. 2003 Mar;284(3):F455-66. Epub 2002 Nov 5.PMID: 12419773 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular biology of protein kinase C signaling in cardiac myocytes.

Malhotra A, Kang BP, Opawumi D, Belizaire W, Meggs LG.

Mol Cell Biochem. 2001 Sep;225(1-):97-107. Review.PMID: 11716370 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I.

Malhotra A, Kang BP, Cheung S, Opawumi D, Meggs LG.

Diabetes. 2001 Aug;50(8):1918-26.PMID: 11473056 [PubMed - indexed for MEDLINE]Related articlesFree article

Emerging concepts in antihypertensive therapy: the benefits of angiotensin II blockade.

Meggs LG, Kodali P.

J Assoc Acad Minor Phys. 1999;10(2):34-43. Review.PMID: 10826007 [PubMed - indexed for MEDLINE]Related articles

Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice.

Leri A, Liu Y, Wang X, Kajstura J, Malhotra A, Meggs LG, Anversa P.

Circ Res. 1999 Apr 16;84(7):752-62.PMID: 10205143 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II activates programmed myocyte cell death in vitro.

Cigola E, Kajstura J, Li B, Meggs LG, Anversa P.

Exp Cell Res. 1997 Mar 15;231(2):363-71.PMID: 9087178 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II induces apoptosis of adult ventricular myocytes in vitro.

Kajstura J, Cigola E, Malhotra A, Li P, Cheng W, Meggs LG, Anversa P.

J Mol Cell Cardiol. 1997 Mar;29(3):859-70.PMID: 9152847 [PubMed - indexed for MEDLINE]Related articles

Coronary artery stenosis in rats affects beta-adrenergic receptor signaling in myocytes.

Meggs LG, Huang HE, Li B, Li P, Coupet J, Hamby CV, Akanuma M, Ishikawa Y, Anversa P.

Cardiovasc Res. 1997 Jan;33(1):98-109.PMID: 9059533 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial infarction alters myofilament calcium sensitivity and mechanical behavior of myocytes.

Li P, Hofmann PA, Li B, Malhotra A, Cheng W, Sonnenblick EH, Meggs LG, Anversa P.

Am J Physiol. 1997 Jan;272(1 Pt 2):H360-70.PMID: 9038957 [PubMed - indexed for MEDLINE]Related articles

Identification and activation of autocrine renin-angiotensin system in adult ventricular myocytes.

Zhang X, Dostal DE, Reiss K, Cheng W, Kajstura J, Li P, Huang H, Sonnenblick EH, Meggs LG, Baker KM, et al.

Am J Physiol. 1995 Nov;269(5 Pt 2):H1791-802.PMID: 7503279 [PubMed - indexed for MEDLINE]Related articles

Fibroblast proliferation during myocardial development in rats is regulated by IGF-1 receptors.

Reiss K, Cheng W, Kajstura J, Sonnenblick EH, Meggs LG, Anversa P.

Am J Physiol. 1995 Sep;269(3 Pt 2):H943-51.PMID: 7573538 [PubMed - indexed for MEDLINE]Related articles

Alterations in angiotensin II receptor mediated signal transduction shortly after coronary artery constriction in the rat.

Huang H, Li P, Hamby CV, Reiss K, Meggs LG, Anversa P.

Cardiovasc Res. 1994 Oct;28(10):1564-73.PMID: 8001047 [PubMed - indexed for MEDLINE]Related articles

Coronary artery constriction in rats affects the activation of alpha 1 adrenergic receptors in cardiac myocytes.

Cheng W, Coupet J, Li P, Reiss K, Hamby CV, Capasso JM, Meggs LG, Anversa P.

Cardiovasc Res. 1994 Jul;28(7):1070-82.PMID: 7954594 [PubMed - indexed for MEDLINE]Related articles

Efficacy of angiotensin-converting enzyme inhibition and AT1 receptor blockade on cardiac pump performance after myocardial infarction in rats.

Capasso JM, Li P, Meggs LG, Herman MV, Anversa P.

J Cardiovasc Pharmacol. 1994 Apr;23(4):584-93.PMID: 7516008 [PubMed - indexed for MEDLINE]Related articles

The cardiocyte as a target for parathyroid hormone in end-stage renal disease.

Meggs LG.

J Assoc Acad Minor Phys. 1994;5(2):59-61. Review.PMID: 8032177 [PubMed - indexed for MEDLINE]Related articles

Upregulation of IGF1, IGF1-receptor, and late growth related genes in ventricular myocytes acutely after infarction in rats.

Reiss K, Meggs LG, Li P, Olivetti G, Capasso JM, Anversa P.

J Cell Physiol. 1994 Jan;158(1):160-8.PMID: 7505276 [PubMed - indexed for MEDLINE]Related articles

Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats.

Meggs LG, Coupet J, Huang H, Cheng W, Li P, Capasso JM, Homcy CJ, Anversa P.

Circ Res. 1993 Jun;72(6):1149-62.PMID: 8495545 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations in ANG II responsiveness in left and right myocardium after infarction-induced heart failure in rats.

Capasso JM, Li P, Zhang X, Meggs LG, Anversa P.

Am J Physiol. 1993 Jun;264(6 Pt 2):H2056-67.PMID: 8322934 [PubMed - indexed for MEDLINE]Related articles

Myocyte loss and left ventricular failure characterise the long term effects of coronary artery narrowing or renal hypertension in rats.

Li P, Zhang X, Capasso JM, Meggs LG, Sonnenblick EH, Anversa P.

Cardiovasc Res. 1993 Jun;27(6):1066-75.PMID: 8221766 [PubMed - indexed for MEDLINE]Related articles

ANG II receptors, c-myc, and c-jun in myocytes after myocardial infarction and ventricular failure.

Reiss K, Capasso JM, Huang HE, Meggs LG, Li P, Anversa P.

Am J Physiol. 1993 Mar;264(3 Pt 2):H760-9.PMID: 8456979 [PubMed - indexed for MEDLINE]Related articles

Re-expression of alpha skeletal actin and regulation of alpha 1 adrenoceptor signalling in DOCA-salt hypertension in rats.

Meggs LG, Huang H, Tillotson J, Capasso JM, Anversa P.

Cardiovasc Res. 1992 Sep;26(9):878-85.PMID: 1333362 [PubMed - indexed for MEDLINE]Related articles

Chronic coronary arterial stenosis impairs alpha 1-adrenoreceptor signaling and cardiac performance in rats.

Meggs LG, Huang H, Li P, Capasso JM, Anversa P.

Am J Physiol. 1992 Sep;263(3 Pt 2):H929-38.PMID: 1329538 [PubMed - indexed for MEDLINE]Related articles

Chronic nonocclusive coronary artery constriction in rats. Beta-adrenoceptor signal transduction and ventricular failure.

Meggs LG, Huang H, Li P, Capasso JM, Anversa P.

J Clin Invest. 1991 Dec;88(6):1940-6.PMID: 1661293 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of asbestos exposure, retroperitoneal fibrosis, and acute renal failure.

Maguire GP, Meggs LG, Addonizio J, Del Guercio LR.

N Y State J Med. 1991 Aug;91(8):357-9. No abstract available. PMID: 1945140 [PubMed - indexed for MEDLINE]Related articles

Cellular basis of chronic ventricular remodeling after myocardial infarction in rats.

Olivetti G, Capasso JM, Meggs LG, Sonnenblick EH, Anversa P.

Circ Res. 1991 Mar;68(3):856-69.PMID: 1742871 [PubMed - indexed for MEDLINE]Related articlesFree article

Noncoordinate regulation of alpha-1 adrenoreceptor coupling and reexpression of alpha skeletal actin in myocardial infarction-induced left ventricular failure in rats.

Meggs LG, Tillotson J, Huang H, Sonnenblick EH, Capasso JM, Anversa P.

J Clin Invest. 1990 Nov;86(5):1451-8.PMID: 2173720 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart.

Anversa P, Palackal T, Sonnenblick EH, Olivetti G, Meggs LG, Capasso JM.

Circ Res. 1990 Oct;67(4):871-85.PMID: 2145091 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptive myocardial hypertrophy in the renal ablation model.

Meggs LG, Ben-Ari J, Gammon D, Choudhury M, Goodman AI.

Am J Hypertens. 1990 Jan;3(1):33-8.PMID: 2154238 [PubMed - indexed for MEDLINE]Related articles

Left ventricular response to exercise and autonomic control mechanisms in end-stage renal disease.

Blake JW, Solangi KB, Herman MV, Goodman AA, Meggs LG.

Arch Intern Med. 1989 Feb;149(2):433-6.PMID: 2916888 [PubMed - indexed for MEDLINE]Related articles

Amelioration of systemic hypertension by converting enzyme inhibition in the renal ablation model.

Meggs LG, Garrick R, Chander P, Ben-Ari J, Gammon D, Goodman AI.

Am J Hypertens. 1988 Apr;1(2):190-2.PMID: 2969741 [PubMed - indexed for MEDLINE]Related articles

Upregulation of the vascular alpha-1 receptor in malignant DOCA-salt hypertension.

Meggs LG, Stitzel R, Ben-Ari J, Chander P, Gammon D, Goodman AI, Head R.

Clin Exp Hypertens A. 1988;10(2):229-47.PMID: 2836114 [PubMed - indexed for MEDLINE]Related articles

Myocardial hypertrophy: the effect of sodium and the role of sympathetic nervous system activity.

Meggs LG, Ben-Ari J, Gammon D, Goodman AI.

Am J Hypertens. 1988 Jan;1(1):11-5.PMID: 2835963 [PubMed - indexed for MEDLINE]Related articles

Effect of chronic uremia on the cardiovascular alpha 1 receptor.

Meggs LG, Ben-Ari J, Gammon D, Choudhury M, Goodman AI.

Life Sci. 1986 Jul 14;39(2):169-79.PMID: 3014252 [PubMed - indexed for MEDLINE]Related articles

Specific desensitization of the canine renal vasculature to angiotensin II despite cyclo-oxygenase inhibition.

Meggs LG, Katzberg RW, DeLeeuw P, Hollenberg NK.

Yale J Biol Med. 1985 Sep-Oct;58(5):453-8.PMID: 3937341 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypertension in blacks. Is it a different disease?

Meggs LG.

N Y State J Med. 1985 Apr;85(4):160-1. No abstract available. PMID: 3857494 [PubMed - indexed for MEDLINE]Related articles

Mechanism of the renal response to contrast medium in dogs. Decrease in renal function due to hypertonicity.

Katzberg RW, Schulman G, Meggs LG, Caldicott WJ, Damiano MM, Hollenberg NK.

Invest Radiol. 1983 Jan-Feb;18(1):74-80.PMID: 6832934 [PubMed - indexed for MEDLINE]Related articles

Contrast medium-induced renal vasoconstriction and endogenous vasoconstrictor hormones.

Katzberg RW, Meggs LG, Schulman G, Hollenberg NK.

Br J Radiol. 1982 Apr;55(652):266-8.PMID: 7066636 [PubMed - indexed for MEDLINE]Related articles

Renal vascular tachyphylaxis to angiotensin II: specificity of the response for angiotensin.

de Leeuw PW, Meggs LG, Hollenberg NK.

Life Sci. 1982 Mar 8;30(10):813-9.PMID: 7070197 [PubMed - indexed for MEDLINE]Related articles

Sodium intake and renal responses to captopril in normal man and in essential hypertension.

Hollenberg NK, Meggs LG, Williams GH, Katz J, Garnic JD, Harrington DP.

Kidney Int. 1981 Aug;20(2):240-5. No abstract available. PMID: 7026873 [PubMed - indexed for MEDLINE]Related articles

When is loss of responsiveness to a vasodilator agent in the patient with congestive heart failure due to tachyphylaxis?

Meggs LG, Hollenberg NK.

Am Heart J. 1980 Nov;100(5):753-4. No abstract available. PMID: 7446368 [PubMed - indexed for MEDLINE]Related articles

Converting enzyme inhibition and the kidney.

Meggs LG, Hollenberg NK.

Hypertension. 1980 Jul-Aug;2(4):551-7. Review.PMID: 6156899 [PubMed - indexed for MEDLINE]Related articlesFree article