PubMed

Dual function microtubule- and mitochondria-associated proteins mediate mitotic cell death.

Liu L, Xie R, Yang C, McKeehan WL.

Cell Oncol. 2009;31(5):393-405.PMID: 19759419 [PubMed - in process]Related articlesFree article

Robust autophagy/mitophagy persists during mitosis.

Liu L, Xie R, Nguyen S, Ye M, McKeehan WL.

Cell Cycle. 2009 May 15;8(10):1616-20. Epub 2009 May 27.PMID: 19411827 [PubMed - indexed for MEDLINE]Related articles

Novel phosphotyrosine targets of FGFR2IIIb signaling.

Luo Y, Yang C, Jin C, Xie R, Wang F, McKeehan WL.

Cell Signal. 2009 Sep;21(9):1370-8. Epub 2009 May 3.PMID: 19410646 [PubMed - indexed for MEDLINE]Related articles

Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis.

Huang X, Yang C, Jin C, Luo Y, Wang F, McKeehan WL.

Mol Carcinog. 2009 Jun;48(6):553-62.PMID: 19009564 [PubMed - indexed for MEDLINE]Related articlesFree article

Restoration of FGF receptor type 2 enhances radiosensitivity of hormone-refractory human prostate carcinoma PC-3 cells.

Matsubara A, Teishima J, Mirkhat S, Yasumoto H, Mochizuki H, Seki M, Mutaguchi K, Mckeehan WL, Usui T.

Anticancer Res. 2008 Jul-Aug;28(4B):2141-6.PMID: 18751387 [PubMed - indexed for MEDLINE]Related articles

Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis.

Zhang Y, Zhang J, Lin Y, Lan Y, Lin C, Xuan JW, Shen MM, McKeehan WL, Greenberg NM, Wang F.

Development. 2008 Feb;135(4):775-84. Epub 2008 Jan 9.PMID: 18184727 [PubMed - indexed for MEDLINE]Related articlesFree article

FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver.

Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL.

Diabetes. 2007 Oct;56(10):2501-10. Epub 2007 Jul 30.PMID: 17664243 [PubMed - indexed for MEDLINE]Related articlesFree article

The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain.

Eriksson M, Samuelsson H, Samuelsson EB, Liu L, McKeehan WL, Benedikz E, Sundström E.

Biochem Biophys Res Commun. 2007 Sep 14;361(1):127-32. Epub 2007 Jul 16.PMID: 17658481 [PubMed - indexed for MEDLINE]Related articles

Lycopene and lutein inhibit proliferation in rat prostate carcinoma cells.

Gunasekera RS, Sewgobind K, Desai S, Dunn L, Black HS, McKeehan WL, Patil B.

Nutr Cancer. 2007;58(2):171-7.PMID: 17640163 [PubMed - indexed for MEDLINE]Related articles

UXT (Ubiquitously Expressed Transcript) causes mitochondrial aggregation.

Moss TN, Vo A, McKeehan WL, Liu L.

In Vitro Cell Dev Biol Anim. 2007 Mar-Apr;43(3-4):139-46. Epub 2007 Mar 21.PMID: 17554592 [PubMed - indexed for MEDLINE]Related articles

High yield, purity and activity of soluble recombinant Bacteroides thetaiotaomicron GST-heparinase I from Escherichia coli.

Luo Y, Huang X, McKeehan WL.

Arch Biochem Biophys. 2007 Apr 1;460(1):17-24. Epub 2007 Feb 16.PMID: 17346663 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis.

Lin Y, Liu G, Zhang Y, Hu YP, Yu K, Lin C, McKeehan K, Xuan JW, Ornitz DM, Shen MM, Greenberg N, McKeehan WL, Wang F.

Development. 2007 Feb;134(4):723-34. Epub 2007 Jan 10.PMID: 17215304 [PubMed - indexed for MEDLINE]Related articlesFree article

Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis.

Huang X, Yu C, Jin C, Yang C, Xie R, Cao D, Wang F, McKeehan WL.

Mol Carcinog. 2006 Dec;45(12):934-42.PMID: 16929488 [PubMed - indexed for MEDLINE]Related articles

Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs.

Luo Y, Ye S, Kan M, McKeehan WL.

J Biol Chem. 2006 Jul 28;281(30):21052-61. Epub 2006 May 25.PMID: 16728399 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of RNA-binding proteins that regulate FGFR2 splicing through the use of sensitive and specific dual color fluorescence minigene assays.

Newman EA, Muh SJ, Hovhannisyan RH, Warzecha CC, Jones RB, McKeehan WL, Carstens RP.

RNA. 2006 Jun;12(6):1129-41. Epub 2006 Apr 7.PMID: 16603716 [PubMed - indexed for MEDLINE]Related articlesFree article

Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis.

Huang X, Yu C, Jin C, Kobayashi M, Bowles CA, Wang F, McKeehan WL.

Cancer Res. 2006 Feb 1;66(3):1481-90.PMID: 16452204 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural specificity in a FGF7-affinity purified heparin octasaccharide required for formation of a complex with FGF7 and FGFR2IIIb.

Luo Y, Ye S, Kan M, McKeehan WL.

J Cell Biochem. 2006 Apr 15;97(6):1241-58.PMID: 16315317 [PubMed - indexed for MEDLINE]Related articles

Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4.

Gutierrez A, Ratliff EP, Andres AM, Huang X, McKeehan WL, Davis RA.

Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):301-6. Epub 2005 Nov 10.PMID: 16284190 [PubMed - indexed for MEDLINE]Related articlesFree article

Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway.

Zhao P, Caretti G, Mitchell S, McKeehan WL, Boskey AL, Pachman LM, Sartorelli V, Hoffman EP.

J Biol Chem. 2006 Jan 6;281(1):429-38. Epub 2005 Nov 2.PMID: 16267055 [PubMed - indexed for MEDLINE]Related articlesFree article

Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein.

Liu L, Vo A, Liu G, McKeehan WL.

Biochem Biophys Res Commun. 2005 Jul 8;332(3):670-6.PMID: 15907802 [PubMed - indexed for MEDLINE]Related articles

Distinct structural domains within C19ORF5 support association with stabilized microtubules and mitochondrial aggregation and genome destruction.

Liu L, Vo A, Liu G, McKeehan WL.

Cancer Res. 2005 May 15;65(10):4191-201.PMID: 15899810 [PubMed - indexed for MEDLINE]Related articlesFree article

Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5.

Liu L, Vo A, McKeehan WL.

Cancer Res. 2005 Mar 1;65(5):1830-8.PMID: 15753381 [PubMed - indexed for MEDLINE]Related articlesFree article

Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids.

Yu C, Wang F, Jin C, Huang X, McKeehan WL.

J Biol Chem. 2005 May 6;280(18):17707-14. Epub 2005 Mar 4.PMID: 15750181 [PubMed - indexed for MEDLINE]Related articlesFree article

Restoration of fibroblast growth factor receptor2 suppresses growth and tumorigenicity of malignant human prostate carcinoma PC-3 cells.

Yasumoto H, Matsubara A, Mutaguchi K, Usui T, McKeehan WL.

Prostate. 2004 Nov 1;61(3):236-42.PMID: 15368475 [PubMed - indexed for MEDLINE]Related articles

Directionally specific paracrine communication mediated by epithelial FGF9 to stromal FGFR3 in two-compartment premalignant prostate tumors.

Jin C, Wang F, Wu X, Yu C, Luo Y, McKeehan WL.

Cancer Res. 2004 Jul 1;64(13):4555-62.PMID: 15231666 [PubMed - indexed for MEDLINE]Related articlesFree article

Improved production of recombinant fibroblast growth factor 7 (FGF7/KGF) from bacteria in high magnesium chloride.

Luo Y, Cho HH, Jones RB, Jin C, McKeehan WL.

Protein Expr Purif. 2004 Feb;33(2):326-31.PMID: 14711521 [PubMed - indexed for MEDLINE]Related articles

Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate.

Jin C, McKeehan K, Guo W, Jauma S, Ittmann MM, Foster B, Greenberg NM, McKeehan WL, Wang F.

Cancer Res. 2003 Dec 15;63(24):8784-90.PMID: 14695195 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia.

Wang F, McKeehan K, Yu C, Ittmann M, McKeehan WL.

Prostate. 2004 Jan 1;58(1):1-12.PMID: 14673947 [PubMed - indexed for MEDLINE]Related articles

Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis.

Yu C, Wang F, Jin C, Huang X, Miller DL, Basilico C, McKeehan WL.

Am J Pathol. 2003 Oct;163(4):1653-62.PMID: 14507672 [PubMed - indexed for MEDLINE]Related articlesFree article

Biospecific extraction and neutralization of anticoagulant heparin with fibroblast growth factors (FGF).

Luo Y, Cho HH, McKeehan WL.

J Pharm Sci. 2003 Oct;92(10):2117-27.PMID: 14502551 [PubMed - indexed for MEDLINE]Related articles

Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors.

Wu X, Jin C, Wang F, Yu C, McKeehan WL.

Cancer Res. 2003 Aug 15;63(16):4936-44.PMID: 12941818 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells.

Liu L, Amy V, Liu G, McKeehan WL.

In Vitro Cell Dev Biol Anim. 2002 Nov-Dec;38(10):582-94.PMID: 12762840 [PubMed - indexed for MEDLINE]Related articles

Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice.

Yu C, Wang F, Jin C, Wu X, Chan WK, McKeehan WL.

Am J Pathol. 2002 Dec;161(6):2003-10.PMID: 12466116 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells.

Burger PE, Coetzee S, McKeehan WL, Kan M, Cook P, Fan Y, Suda T, Hebbel RP, Novitzky N, Muller WA, Wilson EL.

Blood. 2002 Nov 15;100(10):3527-35.PMID: 12411316 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy.

Wang F, McKeehan K, Yu C, McKeehan WL.

Cancer Res. 2002 Mar 15;62(6):1898-903.PMID: 11912171 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity.

Liu L, McKeehan WL.

Genomics. 2002 Jan;79(1):124-36.PMID: 11827465 [PubMed - indexed for MEDLINE]Related articles

Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.

Ye S, Luo Y, Lu W, Jones RB, Linhardt RJ, Capila I, Toida T, Kan M, Pelletier H, McKeehan WL.

Biochemistry. 2001 Dec 4;40(48):14429-39.PMID: 11724555 [PubMed - indexed for MEDLINE]Related articles

Growth inhibition by keratinocyte growth factor receptor of human salivary adenocarcinoma cells through induction of differentiation and apoptosis.

Zhang Y, Wang H, Toratani S, Sato JD, Kan M, McKeehan WL, Okamoto T.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11336-40. Epub 2001 Sep 18.PMID: 11562460 [PubMed - indexed for MEDLINE]Related articlesFree article

5'- and 3'-terminal nucleotides in the FGFR2 ISAR splicing element core have overlapping roles in exon IIIb activation and exon IIIc repression.

Jones RB, Carstens RP, Luo Y, McKeehan WL.

Nucleic Acids Res. 2001 Sep 1;29(17):3557-65.PMID: 11522825 [PubMed - indexed for MEDLINE]Related articlesFree article

A rare premalignant prostate tumor epithelial cell syndecan-1 forms a fibroblast growth factor-binding complex with progression-promoting ectopic fibroblast growth factor receptor 1.

Wu X, Kan M, Wang F, Jin C, Yu C, McKeehan WL.

Cancer Res. 2001 Jul 1;61(13):5295-302.PMID: 11431373 [PubMed - indexed for MEDLINE]Related articlesFree article

Citrus pectin: characterization and inhibitory effect on fibroblast growth factor-receptor interaction.

Liu Y, Ahmad H, Luo Y, Gardiner DT, Gunasekera RS, McKeehan WL, Patil BS.

J Agric Food Chem. 2001 Jun;49(6):3051-7.PMID: 11410008 [PubMed - indexed for MEDLINE]Related articles

Evidence that the intracellular domain of FGF receptor 2IIIb affects contact of the ectodomain with two FGF7 ligands.

Uematsu F, Jang JH, Kan M, Wang F, Luo Y, McKeehan WL.

Biochem Biophys Res Commun. 2001 May 18;283(4):791-7.PMID: 11350054 [PubMed - indexed for MEDLINE]Related articles

The nonsense-mediated decay pathway and mutually exclusive expression of alternatively spliced FGFR2IIIb and -IIIc mRNAs.

Jones RB, Wang F, Luo Y, Yu C, Jin C, Suzuki T, Kan M, McKeehan WL.

J Biol Chem. 2001 Feb 9;276(6):4158-67. Epub 2000 Oct 20.PMID: 11042206 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer.

Jang JH, Shin KH, Park YJ, Lee RJ, McKeehan WL, Park JG.

Cancer Res. 2000 Aug 1;60(15):4049-52.PMID: 10945607 [PubMed - indexed for MEDLINE]Related articlesFree article

Ligand binding properties of binary complexes of heparin and immunoglobulin-like modules of FGF receptor 2.

Uematsu F, Kan M, Wang F, Jang JH, Luo Y, McKeehan WL.

Biochem Biophys Res Commun. 2000 Jun 16;272(3):830-6.PMID: 10860838 [PubMed - indexed for MEDLINE]Related articles

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4.

Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL.

J Biol Chem. 2000 May 19;275(20):15482-9.PMID: 10809780 [PubMed - indexed for MEDLINE]Related articlesFree article

Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway.

Murakami S, Kan M, McKeehan WL, de Crombrugghe B.

Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1113-8.PMID: 10655493 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for digenic inheritance in some cases of Antley-Bixler syndrome?

Reardon W, Smith A, Honour JW, Hindmarsh P, Das D, Rumsby G, Nelson I, Malcolm S, Adès L, Sillence D, Kumar D, DeLozier-Blanchet C, McKee S, Kelly T, McKeehan WL, Baraitser M, Winter RM.

J Med Genet. 2000 Jan;37(1):26-32.PMID: 10633130 [PubMed - indexed for MEDLINE]Related articlesFree article

Androgen-stimulated human prostate epithelial growth mediated by stromal-derived fibroblast growth factor-10.

Nakano K, Fukabori Y, Itoh N, Lu W, Kan M, McKeehan WL, Yamanaka H.

Endocr J. 1999 Jun;46(3):405-13.PMID: 10503993 [PubMed - indexed for MEDLINE]Related articles

Improved recovery of active radiolabeled TGFbeta1 by TGFbeta receptor type III affinity chromatography.

Nakano K, Taniguchi A, Kan M, McKeehan WL.

In Vitro Cell Dev Biol Anim. 1999 May;35(5):241-3. No abstract available. PMID: 10475267 [PubMed - indexed for MEDLINE]Related articles