PubMed

Lost in translation.

Wasserman DH, Ayala JE, McGuinness OP.

Diabetes. 2009 Sep;58(9):1947-50. No abstract available. PMID: 19720822 [PubMed - indexed for MEDLINE]Related articlesFree article

NIH Experiment in Centralized Mouse Phenotyping: The Vanderbilt Experience and Recommendations for Evaluating Glucose Homeostasis in the Mouse.

McGuinness OP, Ayala JE, Laughlin MR, Wasserman DH.

Am J Physiol Endocrinol Metab. 2009 Jul 28. [Epub ahead of print]PMID: 19638507 [PubMed - as supplied by publisher]Related articles

Skeletal muscle AMP-activated protein kinase is essential for the metabolic response to exercise in vivo.

Lee-Young RS, Griffee SR, Lynes SE, Bracy DP, Ayala JE, McGuinness OP, Wasserman DH.

J Biol Chem. 2009 Sep 4;284(36):23925-34. Epub 2009 Jun 12.PMID: 19525228 [PubMed - indexed for MEDLINE]Related articles

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion.

Pound LD, Sarkar SA, Benninger RK, Wang Y, Suwanichkul A, Shadoan MK, Printz RL, Oeser JK, Lee CE, Piston DW, McGuinness OP, Hutton JC, Powell DR, O'Brien RM.

Biochem J. 2009 Jul 15;421(3):371-6.PMID: 19450229 [PubMed - indexed for MEDLINE]Related articles

Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.

Gao Z, Yin J, Zhang J, He Q, McGuinness OP, Ye J.

J Biol Chem. 2009 Jul 3;284(27):18368-76. Epub 2009 May 11.PMID: 19433583 [PubMed - indexed for MEDLINE]Related articles

Insulin signaling in alpha cells modulates glucagon secretion in vivo.

Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN.

Cell Metab. 2009 Apr;9(4):350-61.PMID: 19356716 [PubMed - indexed for MEDLINE]Related articles

Glucagon-mediated impairments in hepatic and peripheral tissue nutrient disposal are not aggravated by increased lipid availability.

Chen SS, Santomango TS, Williams PE, Lacy DB, McGuinness OP.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1172-8. Epub 2009 Feb 10.PMID: 19208853 [PubMed - indexed for MEDLINE]Related articles

Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity.

De Taeye BM, Novitskaya T, McGuinness OP, Gleaves L, Medda M, Covington JW, Vaughan DE.

Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E713-25. Epub 2007 Jun 19.PMID: 17578885 [PubMed - indexed for MEDLINE]Related articlesFree article

Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis.

McGuinness OP.

J Appl Physiol. 2007 Feb;102(2):823; author reply 825. No abstract available. PMID: 17323468 [PubMed - indexed for MEDLINE]Related articles

Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype.

Wang Y, Martin CC, Oeser JK, Sarkar S, McGuinness OP, Hutton JC, O'Brien RM.

Diabetologia. 2007 Apr;50(4):774-8. Epub 2007 Jan 31.PMID: 17265032 [PubMed - indexed for MEDLINE]Related articles

Glycogen synthase kinase 3 inhibition improves insulin-stimulated glucose metabolism but not hypertension in high-fat-fed C57BL/6J mice.

Rao R, Hao CM, Redha R, Wasserman DH, McGuinness OP, Breyer MD.

Diabetologia. 2007 Feb;50(2):452-60. Epub 2006 Dec 7.PMID: 17151860 [PubMed - indexed for MEDLINE]Related articles

Glucagon chronically impairs hepatic and muscle glucose disposal.

Chen SS, Zhang Y, Santomango TS, Williams PE, Lacy DB, McGuinness OP.

Am J Physiol Endocrinol Metab. 2007 Mar;292(3):E928-35. Epub 2006 Nov 28.PMID: 17132827 [PubMed - indexed for MEDLINE]Related articlesFree article

Monoclonal antibody antagonists of hypothalamic FGFR1 cause potent but reversible hypophagia and weight loss in rodents and monkeys.

Sun HD, Malabunga M, Tonra JR, DiRenzo R, Carrick FE, Zheng H, Berthoud HR, McGuinness OP, Shen J, Bohlen P, Leibel RL, Kussie P.

Am J Physiol Endocrinol Metab. 2007 Mar;292(3):E964-76. Epub 2006 Nov 28.PMID: 17132826 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of the gene encoding the ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein (UGRP)/glucose-6-phosphatase catalytic subunit-beta results in lowered plasma cholesterol and elevated glucagon.

Wang Y, Oeser JK, Yang C, Sarkar S, Hackl SI, Hasty AH, McGuinness OP, Paradee W, Hutton JC, Powell DR, O'Brien RM.

J Biol Chem. 2006 Dec 29;281(52):39982-9. Epub 2006 Oct 5.PMID: 17023421 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of portal glucose delivery on glucose metabolism in conscious, unrestrained mice.

Chueh FY, Malabanan C, McGuinness OP.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1206-11. Epub 2006 Jul 5.PMID: 16822956 [PubMed - indexed for MEDLINE]Related articlesFree article

Counterregulatory deficits occur within 24 h of a single hypoglycemic episode in conscious, unrestrained, chronically cannulated mice.

Jacobson L, Ansari T, McGuinness OP.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E678-84.PMID: 16533951 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucocorticoid-deficient corticotropin-releasing hormone knockout mice maintain glucose requirements but not autonomic responses during repeated hypoglycemia.

Jacobson L, Ansari T, Potts J, McGuinness OP.

Am J Physiol Endocrinol Metab. 2006 Jul;291(1):E15-22. Epub 2006 Jan 31.PMID: 16449297 [PubMed - indexed for MEDLINE]Related articlesFree article

Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse.

Ayala JE, Bracy DP, McGuinness OP, Wasserman DH.

Diabetes. 2006 Feb;55(2):390-7.PMID: 16443772 [PubMed - indexed for MEDLINE]Related articlesFree article

Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?

Nunemaker CS, Zhang M, Wasserman DH, McGuinness OP, Powers AC, Bertram R, Sherman A, Satin LS.

Diabetes. 2005 Dec;54(12):3517-22.PMID: 16306370 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia.

Maddux BA, Chang YN, Accili D, McGuinness OP, Youngren JF, Goldfine ID.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E746-9. Epub 2005 Nov 8.PMID: 16278247 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin secretion in the conscious mouse is biphasic and pulsatile.

Nunemaker CS, Wasserman DH, McGuinness OP, Sweet IR, Teague JC, Satin LS.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E523-9. Epub 2005 Oct 25.PMID: 16249252 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of aging in mice by the hormone Klotho.

Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M.

Science. 2005 Sep 16;309(5742):1829-33. Epub 2005 Aug 25.PMID: 16123266 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective glucose homeostasis during infection.

McGuinness OP.

Annu Rev Nutr. 2005;25:9-35. Review.PMID: 16011457 [PubMed - indexed for MEDLINE]Related articles

Route-dependent effect of nutritional support on liver glucose uptake.

Chen SS, Torres-Sanchez CJ, Hosein N, Zhang Y, Lacy DB, Chang C, McGuinness OP.

Am J Physiol Regul Integr Comp Physiol. 2005 Nov;289(5):R1319-27. Epub 2005 Jun 30.PMID: 15994371 [PubMed - indexed for MEDLINE]Related articles

Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake.

Grubert JM, Lautz M, Lacy DB, Moore MC, Farmer B, Penaloza A, Cherrington AD, McGuinness OP.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E232-40. Epub 2005 Mar 8.PMID: 15755768 [PubMed - indexed for MEDLINE]Related articlesFree article

Control of muscle glucose uptake: test of the rate-limiting step paradigm in conscious, unrestrained mice.

Fueger PT, Shearer J, Bracy DP, Posey KA, Pencek RR, McGuinness OP, Wasserman DH.

J Physiol. 2005 Feb 1;562(Pt 3):925-35. Epub 2004 Dec 2.PMID: 15576451 [PubMed - indexed for MEDLINE]Related articlesFree article

Time course of the hepatic adaptation to TPN: interaction with glycogen depletion.

Chen SS, Torres-Sanchez CJ, Hosein N, Zhang Y, Lacy DB, McGuinness OP.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E163-70. Epub 2004 Aug 31.PMID: 15339746 [PubMed - indexed for MEDLINE]Related articlesFree article

Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets.

Rocheleau JV, Walker GM, Head WS, McGuinness OP, Piston DW.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12899-903. Epub 2004 Aug 18.PMID: 15317941 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1.

Ma LJ, Mao SL, Taylor KL, Kanjanabuch T, Guan Y, Zhang Y, Brown NJ, Swift LL, McGuinness OP, Wasserman DH, Vaughan DE, Fogo AB.

Diabetes. 2004 Feb;53(2):336-46.PMID: 14747283 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of infection on glucose-dependent liver glucose uptake during TPN: interaction with insulin.

Chen SS, Donmoyer CM, Pearson DA, Poole A, Zhang Y, Lacy DB, McGuinness OP.

Am J Physiol Endocrinol Metab. 2004 Feb;286(2):E286-95. Epub 2003 Oct 7.PMID: 14532169 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of fructose on hepatic glucose metabolism.

McGuinness OP, Cherrington AD.

Curr Opin Clin Nutr Metab Care. 2003 Jul;6(4):441-8. Review.PMID: 12806219 [PubMed - indexed for MEDLINE]Related articles

Infection impairs insulin-dependent hepatic glucose uptake during total parenteral nutrition.

Donmoyer CM, Chen SS, Lacy DB, Pearson DA, Poole A, Zhang Y, McGuinness OP.

Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E574-82. Epub 2002 Nov 19.PMID: 12441309 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of chronic fructose infusion on hepatic metabolism during TPN administration.

Donmoyer CM, Lacy DB, Zhang Y, Chen SS, McGuinness OP.

Am J Physiol Endocrinol Metab. 2002 Dec;283(6):E1151-8.PMID: 12424103 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of intraportal N(omega)-nitro-L-arginine infusion on hepatic glucose metabolism in total parenteral nutrition-adapted dogs: interaction with infection.

Chen SS, Donmoyer CM, Ejiofor J, McCay J, Archuletta R, Lacy DB, McGuinness OP.

Metabolism. 2002 Mar;51(3):274-83.PMID: 11887160 [PubMed - indexed for MEDLINE]Related articles

Physiological consequences of phasic insulin release in the normal animal.

Cherrington AD, Sindelar D, Edgerton D, Steiner K, McGuinness OP.

Diabetes. 2002 Feb;51 Suppl 1:S103-8. Review.PMID: 11815467 [PubMed - indexed for MEDLINE]Related articlesFree article

Fructose augments infection-impaired net hepatic glucose uptake during TPN administration.

Donmoyer CM, Ejiofor J, Lacy DB, Chen SS, McGuinness OP.

Am J Physiol Endocrinol Metab. 2001 May;280(5):E703-11.PMID: 11287352 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of enteral and parenteral nutrition on hepatic and muscle glucose metabolism.

Chen SS, Donmoyer C, Zhang Y, Hande SA, Lacy DB, McGuinness OP.

JPEN J Parenter Enteral Nutr. 2000 Sep-Oct;24(5):255-60.PMID: 11011779 [PubMed - indexed for MEDLINE]Related articles

Hyperinsulinemia compensates for infection-induced impairment in net hepatic glucose uptake during TPN.

Donmoyer CM, Chen SS, Hande SA, Lacy DB, Ejiofor J, McGuinness OP.

Am J Physiol Endocrinol Metab. 2000 Aug;279(2):E235-43.PMID: 10913021 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic glucose metabolism during intraduodenal glucose infusion: impact of infection.

McGuinness OP, Ejiofor J, Lacy DB, Schrom N.

Am J Physiol Endocrinol Metab. 2000 Jul;279(1):E108-15.PMID: 10893329 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of acute epinephrine removal on hepatic glucose metabolism during stress hormone infusion.

McGuinness OP, Snowden RT, Moran C, Neal DW, Fujiwara T, Cherrington AD.

Metabolism. 1999 Jul;48(7):910-4.PMID: 10421235 [PubMed - indexed for MEDLINE]Related articles

Hepatic production and intestinal uptake of IGF-I: response to infection.

Lang CH, Frost RA, Ejiofor J, Lacy DB, McGuinness OP.

Am J Physiol. 1998 Dec;275(6 Pt 1):G1291-8.PMID: 9843765 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic and muscle glucose metabolism during total parenteral nutrition: impact of infection.

McGuinness OP, Donmoyer C, Ejiofor J, McElligott S, Lacy DB.

Am J Physiol. 1998 Nov;275(5 Pt 1):E763-9.PMID: 9814994 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of glucose production by NEFA and gluconeogenic precursors during chronic glucagon infusion.

McGuinness OP, Ejiofor J, Audoly LP, Schrom N.

Am J Physiol. 1998 Sep;275(3 Pt 1):E432-9.PMID: 9725809 [PubMed - indexed for MEDLINE]Related articlesFree article

Alterations in hepatic gluconeogenic amino acid uptake and gluconeogenesis in the endotoxin treated conscious dog.

Meinz H, Lacy DB, Ejiofor J, McGuinness OP.

Shock. 1998 Apr;9(4):296-303.PMID: 9565259 [PubMed - indexed for MEDLINE]Related articles

Role of epinephrine and norepinephrine in the metabolic response to stress hormone infusion in the conscious dog.

McGuinness OP, Shau V, Benson EM, Lewis M, Snowden RT, Greene JE, Neal DW, Cherrington AD.

Am J Physiol. 1997 Oct;273(4 Pt 1):E674-81.PMID: 9357794 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of insulin action on glucose uptake and production during a euglycemic-hyperinsulinemic clamp in dog: a new kinetic analysis.

McGuinness OP, Mari A.

Metabolism. 1997 Oct;46(10):1116-27.PMID: 9322792 [PubMed - indexed for MEDLINE]Related articles

Hepatic release of tumor necrosis factor in the endotoxin-treated conscious dog.

McGuinness OP, Lacy DB, Ejiofor J, Bagby GG.

Shock. 1996 May;5(5):344-8.PMID: 9156790 [PubMed - indexed for MEDLINE]Related articles

Role of cortisol in the metabolic response to stress hormone infusion in the conscious dog.

Fujiwara T, Cherrington AD, Neal DN, McGuinness OP.

Metabolism. 1996 May;45(5):571-8.PMID: 8622599 [PubMed - indexed for MEDLINE]Related articles

Hyperglucagonemia and hepatic glucose metabolism during infection in the conscious dog.

McGuinness OP, Lacy DB, Eliasson K.

Am J Physiol. 1996 Apr;270(4 Pt 1):E580-8.PMID: 8928762 [PubMed - indexed for MEDLINE]Related articles

Impact of infection on hepatic disposal of a peripheral glucose infusion in the conscious dog.

McGuinness OP, Jacobs J, Moran C, Lacy B.

Am J Physiol. 1995 Aug;269(2 Pt 1):E199-207.PMID: 7653536 [PubMed - indexed for MEDLINE]Related articles