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    Results: 10

    1.

    In vivo knockdown of p85alpha with an antisense oligonucleotide improves insulin sensitivity in Lep(ob/ob) and diet-induced obese mice.

    Moriarty MW, McCurdy CE, Janssen RC, Shaw T, Leitner JW, Friedman JE, Draznin B.

    Horm Metab Res. 2009 Oct;41(10):757-61. Epub 2009 Jul 13.PMID: 19598077 [PubMed - in process]Related articles

    2.

    Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates.

    McCurdy CE, Bishop JM, Williams SM, Grayson BE, Smith MS, Friedman JE, Grove KL.

    J Clin Invest. 2009 Feb;119(2):323-35. doi: 10.1172/JCI32661. Epub 2009 Jan 19.PMID: 19147984 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues.

    Wang H, Knaub LA, Jensen DR, Young Jung D, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la Houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Soo Choi C, Shulman GI, Kim JK, Friedman JE, Eckel RH.

    Diabetes. 2009 Jan;58(1):116-24. Epub 2008 Oct 24.PMID: 18952837 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes.

    Barbour LA, McCurdy CE, Hernandez TL, Kirwan JP, Catalano PM, Friedman JE.

    Diabetes Care. 2007 Jul;30 Suppl 2:S112-9. No abstract available. Erratum in: Diabetes Care. 2007 Dec;30(12):3154. PMID: 17596458 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance.

    del Rincon JP, Iida K, Gaylinn BD, McCurdy CE, Leitner JW, Barbour LA, Kopchick JJ, Friedman JE, Draznin B, Thorner MO.

    Diabetes. 2007 Jun;56(6):1638-46. Epub 2007 Mar 15.PMID: 17363744 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Early foetal programming of hepatic gluconeogenesis: Glucocorticoids strike back.

    McCurdy CE, Friedman JE.

    Diabetologia. 2006 Jun;49(6):1138-41. No abstract available. PMID: 16680490 [PubMed - indexed for MEDLINE]Related articles

    7.

    Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess.

    Barbour LA, Mizanoor Rahman S, Gurevich I, Leitner JW, Fischer SJ, Roper MD, Knotts TA, Vo Y, McCurdy CE, Yakar S, Leroith D, Kahn CR, Cantley LC, Friedman JE, Draznin B.

    J Biol Chem. 2005 Nov 11;280(45):37489-94. Epub 2005 Sep 8.PMID: 16166093 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Akt2 is essential for the full effect of calorie restriction on insulin-stimulated glucose uptake in skeletal muscle.

    McCurdy CE, Cartee GD.

    Diabetes. 2005 May;54(5):1349-56.PMID: 15855319 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle.

    McCurdy CE, Davidson RT, Cartee GD.

    Am J Physiol Endocrinol Metab. 2005 May;288(5):E996-E1001. Epub 2004 Dec 21.PMID: 15613677 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Brief calorie restriction increases Akt2 phosphorylation in insulin-stimulated rat skeletal muscle.

    McCurdy CE, Davidson RT, Cartee GD.

    Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E693-700. Epub 2003 Jun 10.PMID: 12799317 [PubMed - indexed for MEDLINE]Related articlesFree article

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