PubMed

Integrase-defective lentiviral vectors: progress and applications.

Banasik MB, McCray PB Jr.

Gene Ther. 2009 Oct 22. [Epub ahead of print]PMID: 19847206 [PubMed - as supplied by publisher]Related articles

Differential effects of cytokines and corticosteroids on Toll-like receptor 2 expression and activity in human airway epithelia.

Winder AA, Wohlford-Lenane C, Scheetz TE, Nardy BN, Manzel LJ, Look DC, McCray PB Jr.

Respir Res. 2009 Oct 16;10:96.PMID: 19835594 [PubMed - in process]Related articlesFree article

Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease.

Wohlford-Lenane CL, Meyerholz DK, Perlman S, Zhou H, Tran D, Selsted ME, McCray PB Jr.

J Virol. 2009 Nov;83(21):11385-90. Epub 2009 Aug 26.PMID: 19710146 [PubMed - in process]Related articles

Progress and prospects: prospects of repeated pulmonary administration of viral vectors.

Sinn PL, Burnight ER, McCray PB Jr.

Gene Ther. 2009 Sep;16(9):1059-65. Epub 2009 Jul 30.PMID: 19641533 [PubMed - in process]Related articles

Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors.

Quinn K, Brindley MA, Weller ML, Kaludov N, Kondratowicz A, Hunt CL, Sinn PL, McCray PB Jr, Stein CS, Davidson BL, Flick R, Mandell R, Staplin W, Maury W, Chiorini JA.

J Virol. 2009 Oct;83(19):10176-86. Epub 2009 Jul 22.PMID: 19625394 [PubMed - indexed for MEDLINE]Related articles

Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia.

Jia HP, Look DC, Tan P, Shi L, Hickey M, Gakhar L, Chappell MC, Wohlford-Lenane C, McCray PB Jr.

Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L84-96. Epub 2009 May 1.PMID: 19411314 [PubMed - indexed for MEDLINE]Related articles

The piglet as a model for B cell and immune system development.

Butler JE, Lager KM, Splichal I, Francis D, Kacskovics I, Sinkora M, Wertz N, Sun J, Zhao Y, Brown WR, DeWald R, Dierks S, Muyldermans S, Lunney JK, McCray PB, Rogers CS, Welsh MJ, Navarro P, Klobasa F, Habe F, Ramsoondar J.

Vet Immunol Immunopathol. 2009 Mar 15;128(1-3):147-70. Epub 2008 Nov 1. Review.PMID: 19056129 [PubMed - indexed for MEDLINE]Related articles

Cytokine-mediated regulation of antimicrobial proteins.

Kolls JK, McCray PB Jr, Chan YR.

Nat Rev Immunol. 2008 Nov;8(11):829-35. Review.PMID: 18949018 [PubMed - indexed for MEDLINE]Related articles

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T, Taft PJ, Rogan MP, Pezzulo AA, Karp PH, Itani OA, Kabel AC, Wohlford-Lenane CL, Davis GJ, Hanfland RA, Smith TL, Samuel M, Wax D, Murphy CN, Rieke A, Whitworth K, Uc A, Starner TD, Brogden KA, Shilyansky J, McCray PB Jr, Zabner J, Prather RS, Welsh MJ.

Science. 2008 Sep 26;321(5897):1837-41.PMID: 18818360 [PubMed - indexed for MEDLINE]Related articlesFree article

Lentivirus vector can be readministered to nasal epithelia without blocking immune responses.

Sinn PL, Arias AC, Brogden KA, McCray PB Jr.

J Virol. 2008 Nov;82(21):10684-92. Epub 2008 Sep 3.PMID: 18768988 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential gene expression in human conducting airway surface epithelia and submucosal glands.

Fischer AJ, Goss KL, Scheetz TE, Wohlford-Lenane CL, Snyder JM, McCray PB Jr.

Am J Respir Cell Mol Biol. 2009 Feb;40(2):189-99. Epub 2008 Aug 14.PMID: 18703793 [PubMed - indexed for MEDLINE]Related articles

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.

Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, Göbel C, Dassie JP, Pruett-Miller SM, Porteus MH, Sgroi DC, Iafrate AJ, Dobbs D, McCray PB Jr, Cathomen T, Voytas DF, Joung JK.

Mol Cell. 2008 Jul 25;31(2):294-301.PMID: 18657511 [PubMed - indexed for MEDLINE]Related articlesFree article

Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed.

Leonard VH, Sinn PL, Hodge G, Miest T, Devaux P, Oezguen N, Braun W, McCray PB Jr, McChesney MB, Cattaneo R.

J Clin Invest. 2008 Jul;118(7):2448-58.PMID: 18568079 [PubMed - indexed for MEDLINE]Related articlesFree article

Innate immune functions of the airway epithelium.

Bartlett JA, Fischer AJ, McCray PB Jr.

Contrib Microbiol. 2008;15:147-63. Review.PMID: 18511860 [PubMed - indexed for MEDLINE]Related articles

The porcine lung as a potential model for cystic fibrosis.

Rogers CS, Abraham WM, Brogden KA, Engelhardt JF, Fisher JT, McCray PB Jr, McLennan G, Meyerholz DK, Namati E, Ostedgaard LS, Prather RS, Sabater JR, Stoltz DA, Zabner J, Welsh MJ.

Am J Physiol Lung Cell Mol Physiol. 2008 Aug;295(2):L240-63. Epub 2008 May 16. Review.PMID: 18487356 [PubMed - indexed for MEDLINE]Related articlesFree article

Basolateral entry and release of New and Old World arenaviruses from human airway epithelia.

Dylla DE, Michele DE, Campbell KP, McCray PB Jr.

J Virol. 2008 Jun;82(12):6034-8. Epub 2008 Apr 16.PMID: 18417570 [PubMed - indexed for MEDLINE]Related articlesFree article

PLUNC is a secreted product of neutrophil granules.

Bartlett JA, Hicks BJ, Schlomann JM, Ramachandran S, Nauseef WM, McCray PB Jr.

J Leukoc Biol. 2008 May;83(5):1201-6. Epub 2008 Feb 1.PMID: 18245229 [PubMed - indexed for MEDLINE]Related articlesFree article

MD-2-dependent pulmonary immune responses to inhaled lipooligosaccharides: effect of acylation state.

Hadina S, Weiss JP, McCray PB Jr, Kulhankova K, Thorne PS.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):647-54. Epub 2008 Jan 18.PMID: 18203970 [PubMed - indexed for MEDLINE]Related articlesFree article

JunD protects the liver from ischemia/reperfusion injury by dampening AP-1 transcriptional activation.

Marden JJ, Zhang Y, Oakley FD, Zhou W, Luo M, Jia HP, McCray PB Jr, Yaniv M, Weitzman JB, Engelhardt JF.

J Biol Chem. 2008 Mar 14;283(11):6687-95. Epub 2008 Jan 8.PMID: 18182393 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo imaging of gene transfer to the respiratory tract.

Griesenbach U, Meng C, Farley R, Cheng SH, Scheule RK, Davies MH, Wolstenholme-Hogg PC, ten Hove W, van der Hoeven P, Sinn PL, McCray PB Jr, Inoue M, Geddes DM, Hasegawa M, Frankel G, Wiles S, Alton EW.

Biomaterials. 2008 Apr;29(10):1533-40. Epub 2007 Dec 21.PMID: 18155138 [PubMed - indexed for MEDLINE]Related articles

Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector.

Sinn PL, Goreham-Voss JD, Arias AC, Hickey MA, Maury W, Chikkanna-Gowda CP, McCray PB Jr.

Hum Gene Ther. 2007 Dec;18(12):1244-52.PMID: 18052720 [PubMed - indexed for MEDLINE]Related articles

Ebola virus glycoprotein 1: identification of residues important for binding and postbinding events.

Brindley MA, Hughes L, Ruiz A, McCray PB Jr, Sanchez A, Sanders DA, Maury W.

J Virol. 2007 Jul;81(14):7702-9. Epub 2007 May 2.PMID: 17475648 [PubMed - indexed for MEDLINE]Related articlesFree article

Viral vector-mediated and cell-based therapies for treatment of cystic fibrosis.

Flotte TR, Ng P, Dylla DE, McCray PB Jr, Wang G, Kolls JK, Hu J.

Mol Ther. 2007 Feb;15(2):229-41. Review.PMID: 17235299 [PubMed - indexed for MEDLINE]Related articles

Characterization of monoclonal antibodies to human soluble MD-2 protein.

Viriyakosol S, McCray PB, Ashbaugh ME, Chu J, Jia HP, Weiss J, Kirkland TN.

Hybridoma (Larchmt). 2006 Dec;25(6):349-57.PMID: 17203997 [PubMed - indexed for MEDLINE]Related articles

A novel host defense system of airways is defective in cystic fibrosis.

Moskwa P, Lorentzen D, Excoffon KJ, Zabner J, McCray PB Jr, Nauseef WM, Dupuy C, Bánfi B.

Am J Respir Crit Care Med. 2007 Jan 15;175(2):174-83. Epub 2006 Nov 2.PMID: 17082494 [PubMed - indexed for MEDLINE]Related articlesFree article

Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus.

McCray PB Jr, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S.

J Virol. 2007 Jan;81(2):813-21. Epub 2006 Nov 1.PMID: 17079315 [PubMed - indexed for MEDLINE]Related articlesFree article

Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localization.

Jia HP, Look DC, Hickey M, Shi L, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB Jr.

Adv Exp Med Biol. 2006;581:479-84. Review. No abstract available. PMID: 17037581 [PubMed - indexed for MEDLINE]Related articles

Monocytic/macrophagic pneumonitis after intrabronchial deposition of vascular endothelial growth factor in neonatal lambs.

Meyerholz DK, Grubor B, Lazic T, Gallup JM, de Macedo MM, McCray PB Jr, Ackermann MR.

Vet Pathol. 2006 Sep;43(5):689-94.PMID: 16966446 [PubMed - indexed for MEDLINE]Related articlesFree article

Integration site choice of a feline immunodeficiency virus vector.

Kang Y, Moressi CJ, Scheetz TE, Xie L, Tran DT, Casavant TL, Ak P, Benham CJ, Davidson BL, McCray PB Jr.

J Virol. 2006 Sep;80(17):8820-3.PMID: 16912328 [PubMed - indexed for MEDLINE]Related articlesFree article

Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis.

Starner TD, Zhang N, Kim G, Apicella MA, McCray PB Jr.

Am J Respir Crit Care Med. 2006 Jul 15;174(2):213-20. Epub 2006 May 4.PMID: 16675778 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathogenesis of early lung disease in cystic fibrosis: a window of opportunity to eradicate bacteria.

Starner TD, McCray PB Jr; American College of Physicians; American Physiological Society.

Ann Intern Med. 2005 Dec 6;143(11):816-22. Review. No abstract available. PMID: 16330793 [PubMed - indexed for MEDLINE]Related articlesFree article

ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia.

Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB Jr.

J Virol. 2005 Dec;79(23):14614-21.PMID: 16282461 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer.

Sinn PL, Burnight ER, Hickey MA, Blissard GW, McCray PB Jr.

J Virol. 2005 Oct;79(20):12818-27.PMID: 16188984 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

Sinn PL, Sauter SL, McCray PB Jr.

Gene Ther. 2005 Jul;12(14):1089-98. Review.PMID: 16003340 [PubMed - indexed for MEDLINE]Related articles

CFTR DeltaF508 mutation has minimal effect on the gene expression profile of differentiated human airway epithelia.

Zabner J, Scheetz TE, Almabrazi HG, Casavant TL, Huang J, Keshavjee S, McCray PB Jr.

Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L545-53. Epub 2005 Jun 3.PMID: 15937068 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer.

Kang Y, Xie L, Tran DT, Stein CS, Hickey M, Davidson BL, McCray PB Jr.

Blood. 2005 Sep 1;106(5):1552-8. Epub 2005 May 10.PMID: 15886327 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene transfer to respiratory epithelia with lentivirus pseudotyped with Jaagsiekte sheep retrovirus envelope glycoprotein.

Sinn PL, Penisten AK, Burnight ER, Hickey MA, Williams G, McCoy DM, Mallampalli RK, McCray PB.

Hum Gene Ther. 2005 Apr;16(4):479-88.PMID: 15871679 [PubMed - indexed for MEDLINE]Related articles

Correlation between beta-defensin expression and induction profiles in gingival keratinocytes.

Joly S, Organ CC, Johnson GK, McCray PB Jr, Guthmiller JM.

Mol Immunol. 2005 May;42(9):1073-84. Epub 2004 Dec 15.PMID: 15829297 [PubMed - indexed for MEDLINE]Related articles

Inclusion of Jaagsiekte sheep retrovirus proviral elements markedly increases lentivirus vector pseudotyping efficiency.

Sinn PL, Burnight ER, Shen H, Fan H, McCray PB Jr.

Mol Ther. 2005 Mar;11(3):460-9.PMID: 15727943 [PubMed - indexed for MEDLINE]Related articles

Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors.

Sinn PL, Shah AJ, Donovan MD, McCray PB Jr.

Am J Respir Cell Mol Biol. 2005 May;32(5):404-10. Epub 2005 Feb 4.PMID: 15695737 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and activity of beta-defensins and LL-37 in the developing human lung.

Starner TD, Agerberth B, Gudmundsson GH, McCray PB Jr.

J Immunol. 2005 Feb 1;174(3):1608-15.PMID: 15661923 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction in the bactericidal activity of selected cathelicidin peptides by bovine calf serum or exogenous endotoxin.

Bartlett KH, McCray PB Jr, Thorne PS.

Int J Antimicrob Agents. 2004 Jun;23(6):606-12.PMID: 15194132 [PubMed - indexed for MEDLINE]Related articles

Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2.

Jia HP, Kline JN, Penisten A, Apicella MA, Gioannini TL, Weiss J, McCray PB Jr.

Am J Physiol Lung Cell Mol Physiol. 2004 Aug;287(2):L428-37. Epub 2004 Apr 30.PMID: 15121639 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of beta-defensins in gingival health and in periodontal disease.

Bissell J, Joly S, Johnson GK, Organ CC, Dawson D, McCray PB Jr, Guthmiller JM.

J Oral Pathol Med. 2004 May;33(5):278-85.PMID: 15078488 [PubMed - indexed for MEDLINE]Related articles

Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms.

Joly S, Maze C, McCray PB Jr, Guthmiller JM.

J Clin Microbiol. 2004 Mar;42(3):1024-9.PMID: 15004048 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and regulation of novel human beta-defensins in gingival keratinocytes.

Premratanachai P, Joly S, Johnson GK, McCray PB Jr, Jia HP, Guthmiller JM.

Oral Microbiol Immunol. 2004 Apr;19(2):111-7.PMID: 14871351 [PubMed - indexed for MEDLINE]Related articles

Large-scale gene discovery in human airway epithelia reveals novel transcripts.

Scheetz TE, Zabner J, Welsh MJ, Coco J, Eyestone Mde F, Bonaldo M, Kucaba T, Casavant TL, Soares MB, McCray PB Jr.

Physiol Genomics. 2004 Mar 12;17(1):69-77.PMID: 14701920 [PubMed - indexed for MEDLINE]Related articles

Novispirin G10-induced lung toxicity in a Klebsiella pneumoniae infection model.

Bartlett KH, McCray PB Jr, Thorne PS.

Antimicrob Agents Chemother. 2003 Dec;47(12):3901-6.PMID: 14638500 [PubMed - indexed for MEDLINE]Related articlesFree article

Antimicrobial peptides in animals and their role in host defences.

Brogden KA, Ackermann M, McCray PB Jr, Tack BF.

Int J Antimicrob Agents. 2003 Nov;22(5):465-78. Review.PMID: 14602364 [PubMed - indexed for MEDLINE]Related articles

Developmental expression and distribution of sheep beta-defensin-2.

Meyerholz DK, Gallup JM, Grubor BM, Evans RB, Tack BF, McCray PB Jr, Ackermann MR.

Dev Comp Immunol. 2004 Feb;28(2):171-8.PMID: 12969802 [PubMed - indexed for MEDLINE]Related articles