PubMed

KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803.

Ogino S, Meyerhardt JA, Irahara N, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Schaefer P, Whittom R, Hantel A, Benson AB 3rd, Goldberg RM, Bertagnolli MM, Fuchs CS; for the Cancer and Leukemia Group B, North Central Cancer Treatment Group, Canadian Cancer Society Research Institute, Southwest Oncology Group.

Clin Cancer Res. 2009 Nov 24. [Epub ahead of print]PMID: 19934290 [PubMed - as supplied by publisher]

Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer: CALGB 89904.

Kulke MH, Tempero MA, Niedzwiecki D, Hollis DR, Kindler HL, Cusnir M, Enzinger PC, Gorsch SM, Goldberg RM, Mayer RJ.

J Clin Oncol. 2009 Nov 20;27(33):5506-12. Epub 2009 Oct 26.PMID: 19858396 [PubMed - in process]Related articles

By the way, doctor. We have screening tests for other cancers. How about pancreatic cancer?

Mayer RJ.

Harv Health Lett. 2009 May;34(7):1. No abstract available. PMID: 19565666 [PubMed - indexed for MEDLINE]Related articles

Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration.

Paine S, Bedford L, Thorpe JR, Mayer RJ, Cavey JR, Bajaj N, Sheppard PW, Lowe J, Layfield R.

Neurosci Lett. 2009 Sep 4;460(3):205-8. Epub 2009 Jun 7.PMID: 19500650 [PubMed - indexed for MEDLINE]Related articles

A compendium of potential biomarkers of pancreatic cancer.

Harsha HC, Kandasamy K, Ranganathan P, Rani S, Ramabadran S, Gollapudi S, Balakrishnan L, Dwivedi SB, Telikicherla D, Selvan LD, Goel R, Mathivanan S, Marimuthu A, Kashyap M, Vizza RF, Mayer RJ, Decaprio JA, Srivastava S, Hanash SM, Hruban RH, Pandey A.

PLoS Med. 2009 Apr 7;6(4):e1000046. Epub 2009 Apr 7. Review. No abstract available. PMID: 19360088 [PubMed - indexed for MEDLINE]Related articlesFree article

p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803.

Bertagnolli MM, Warren RS, Niedzwiecki D, Mueller E, Compton CC, Redston M, Hall M, Hahn HP, Jewell SD, Mayer RJ, Goldberg RM, Saltz LB, Loda M.

Clin Cancer Res. 2009 Mar 15;15(6):2116-22. Epub 2009 Mar 10.PMID: 19276255 [PubMed - indexed for MEDLINE]Related articles

Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.

Bertagnolli MM, Niedzwiecki D, Compton CC, Hahn HP, Hall M, Damas B, Jewell SD, Mayer RJ, Goldberg RM, Saltz LB, Warren RS, Redston M.

J Clin Oncol. 2009 Apr 10;27(11):1814-21. Epub 2009 Mar 9.PMID: 19273709 [PubMed - indexed for MEDLINE]Related articles

Targeted therapy for advanced colorectal cancer--more is not always better.

Mayer RJ.

N Engl J Med. 2009 Feb 5;360(6):623-5. No abstract available. PMID: 19196680 [PubMed - indexed for MEDLINE]Related articles

US intergroup anal carcinoma trial: tumor diameter predicts for colostomy.

Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett CG.

J Clin Oncol. 2009 Mar 1;27(7):1116-21. Epub 2009 Jan 12.PMID: 19139424 [PubMed - indexed for MEDLINE]Related articles

Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer.

Enzinger PC, Ryan DP, Clark JW, Muzikansky A, Earle CC, Kulke MH, Meyerhardt JA, Blaszkowsky LS, Zhu AX, Fidias P, Vincitore MM, Mayer RJ, Fuchs CS.

Ann Oncol. 2009 Mar;20(3):475-80. Epub 2009 Jan 12.PMID: 19139178 [PubMed - indexed for MEDLINE]Related articles

The UPS and autophagy in chronic neurodegenerative disease: six of one and half a dozen of the other--or not?

Bedford L, Paine S, Rezvani N, Mee M, Lowe J, Mayer RJ.

Autophagy. 2009 Feb;5(2):224-7. Epub 2009 Feb 13.PMID: 19077533 [PubMed - indexed for MEDLINE]Related articles

Is malfunction of the ubiquitin proteasome system the primary cause of alpha-synucleinopathies and other chronic human neurodegenerative disease?

Bedford L, Hay D, Paine S, Rezvani N, Mee M, Lowe J, Mayer RJ.

Biochim Biophys Acta. 2008 Dec;1782(12):683-90. Epub 2008 Oct 25. Review.PMID: 18976704 [PubMed - indexed for MEDLINE]Related articles

The ubiquitin proteasome system in human disease.

Layfield R, Mayer RJ.

Biochim Biophys Acta. 2008 Dec;1782(12):681-2. Epub 2008 Sep 18. No abstract available. PMID: 18845251 [PubMed - indexed for MEDLINE]Related articles

Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803.

Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Nelson H, Whittom R, Hantel A, Thomas J, Fuchs CS; Cancer and Leukemia Group B 89803.

J Clin Oncol. 2008 Sep 1;26(25):4109-15.PMID: 18757324 [PubMed - indexed for MEDLINE]Related articlesFree article

Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.

Bedford L, Hay D, Devoy A, Paine S, Powe DG, Seth R, Gray T, Topham I, Fone K, Rezvani N, Mee M, Soane T, Layfield R, Sheppard PW, Ebendal T, Usoskin D, Lowe J, Mayer RJ.

J Neurosci. 2008 Aug 13;28(33):8189-98.PMID: 18701681 [PubMed - indexed for MEDLINE]Related articlesFree article

By the way, doctor. Cancer of the small intestine.

Mayer RJ.

Harv Health Lett. 2008 May;33(7):7. No abstract available. PMID: 18697271 [PubMed - indexed for MEDLINE]Related articles

Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study.

Neubauer A, Maharry K, Mrózek K, Thiede C, Marcucci G, Paschka P, Mayer RJ, Larson RA, Liu ET, Bloomfield CD.

J Clin Oncol. 2008 Oct 1;26(28):4603-9. Epub 2008 Jun 16.PMID: 18559876 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of family history with cancer recurrence and survival among patients with stage III colon cancer.

Chan JA, Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Thomas J, Schaefer P, Whittom R, Hantel A, Goldberg RM, Warren RS, Bertagnolli M, Fuchs CS.

JAMA. 2008 Jun 4;299(21):2515-23.PMID: 18523220 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction therapy for poor-prognosis anal canal carcinoma: a phase II study of the cancer and Leukemia Group B (CALGB 9281).

Meropol NJ, Niedzwiecki D, Shank B, Colacchio TA, Ellerton J, Valone F, Budinger S, Day JM, Hopkins J, Tepper J, Goldberg RM, Mayer RJ.

J Clin Oncol. 2008 Jul 1;26(19):3229-34. Epub 2008 May 19.PMID: 18490648 [PubMed - indexed for MEDLINE]Related articles

Systemic treatment of colorectal cancer.

Wolpin BM, Mayer RJ.

Gastroenterology. 2008 May;134(5):1296-310. Review.PMID: 18471507 [PubMed - indexed for MEDLINE]Related articlesFree article

Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.

Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett C.

JAMA. 2008 Apr 23;299(16):1914-21.PMID: 18430910 [PubMed - indexed for MEDLINE]Related articlesFree article

AAA proteins and the life process.

Förster A, Freemont PS, Mayer RJ.

Biochem Soc Trans. 2008 Feb;36(Pt 1):59-61.PMID: 18208386 [PubMed - indexed for MEDLINE]Related articles

Clinical cancer advances 2007: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.

Gralow J, Ozols RF, Bajorin DF, Cheson BD, Sandler HM, Winer EP, Bonner J, Demetri GD, Curran W Jr, Ganz PA, Kramer BS, Kris MG, Markman M, Mayer RJ, Raghavan D, Ramsey S, Reaman GH, Sawaya R, Schuchter LM, Sweetenham JW, Vahdat LT, Davidson NE, Schilsky RL, Lichter AS; American Society of Clinical Oncology.

J Clin Oncol. 2008 Jan 10;26(2):313-25. Epub 2007 Dec 17. Erratum in: J Clin Oncol. 2008 Mar 10;26(8):1394. PMID: 18086794 [PubMed - indexed for MEDLINE]Related articles

A phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: cancer and leukemia group B study 89903.

Posner MC, Niedzwiecki D, Venook AP, Hollis DR, Kindler HL, Martin EW, Schilsky RL, Goldberg RM, Mayer RJ.

Ann Surg Oncol. 2008 Jan;15(1):158-64. Epub 2007 Nov 16. Erratum in: Ann Surg Oncol. 2009 Aug;16(8):2381. Mayer, Robert J [added]. PMID: 18008108 [PubMed - indexed for MEDLINE]Related articles

Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage.

Tudhope SJ, Finney-Hayward TK, Nicholson AG, Mayer RJ, Barnette MS, Barnes PJ, Donnelly LE.

J Pharmacol Exp Ther. 2008 Jan;324(1):306-12. Epub 2007 Oct 5.PMID: 17921189 [PubMed - indexed for MEDLINE]Related articlesFree article

Should capecitabine replace infusional fluorouracil and leucovorin when combined with oxaliplatin in metastatic colorectal cancer?

Mayer RJ.

J Clin Oncol. 2007 Sep 20;25(27):4165-7. Epub 2007 Aug 20. No abstract available. PMID: 17709796 [PubMed - indexed for MEDLINE]Related articles

Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer.

Meyerhardt JA, Niedzwiecki D, Hollis D, Saltz LB, Hu FB, Mayer RJ, Nelson H, Whittom R, Hantel A, Thomas J, Fuchs CS.

JAMA. 2007 Aug 15;298(7):754-64.PMID: 17699009 [PubMed - indexed for MEDLINE]Related articlesFree article

Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803.

Saltz LB, Niedzwiecki D, Hollis D, Goldberg RM, Hantel A, Thomas JP, Fields AL, Mayer RJ.

J Clin Oncol. 2007 Aug 10;25(23):3456-61.PMID: 17687149 [PubMed - indexed for MEDLINE]Related articles

Adjuvant treatment of colorectal cancer.

Wolpin BM, Meyerhardt JA, Mamon HJ, Mayer RJ.

CA Cancer J Clin. 2007 May-Jun;57(3):168-85. Review.PMID: 17507442 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase II study of FOLFOX, bevacizumab and erlotinib as first-line therapy for patients with metastatic colorectal cancer.

Meyerhardt JA, Stuart K, Fuchs CS, Zhu AX, Earle CC, Bhargava P, Blaszkowsky L, Enzinger P, Mayer RJ, Battu S, Lawrence C, Ryan DP.

Ann Oncol. 2007 Jul;18(7):1185-9. Epub 2007 May 4.PMID: 17483115 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer.

Meyerhardt JA, Clark JW, Supko JG, Eder JP, Ogino S, Stewart CF, D'Amato F, Dancey J, Enzinger PC, Zhu AX, Ryan DP, Earle CC, Mayer RJ, Michelini A, Kinsella K, Fuchs CS.

Cancer Chemother Pharmacol. 2007 Oct;60(5):661-70. Epub 2007 Jan 11.PMID: 17216531 [PubMed - indexed for MEDLINE]Related articles

Clinical cancer advances 2006: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.

Ozols RF, Herbst RS, Colson YL, Gralow J, Bonner J, Curran WJ Jr, Eisenberg BL, Ganz PA, Kramer BS, Kris MG, Markman M, Mayer RJ, Raghavan D, Reaman GH, Sawaya R, Schilsky RL, Schuchter LM, Sweetenham JW, Vahdat LT, Winn RJ; American Society of Clinical Oncology.

J Clin Oncol. 2007 Jan 1;25(1):146-62. Epub 2006 Dec 8.PMID: 17158528 [PubMed - indexed for MEDLINE]Related articles

The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.

Goel A, Nagasaka T, Arnold CN, Inoue T, Hamilton C, Niedzwiecki D, Compton C, Mayer RJ, Goldberg R, Bertagnolli MM, Boland CR.

Gastroenterology. 2007 Jan;132(1):127-38. Epub 2006 Sep 20.PMID: 17087942 [PubMed - indexed for MEDLINE]Related articles

Gankyrin, the 26 S proteasome, the cell cycle and cancer.

Mayer RJ, Fujita J.

Biochem Soc Trans. 2006 Nov;34(Pt 5):746-8.PMID: 17052188 [PubMed - indexed for MEDLINE]Related articles

Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines.

Lenz HJ, Van Cutsem E, Khambata-Ford S, Mayer RJ, Gold P, Stella P, Mirtsching B, Cohn AL, Pippas AW, Azarnia N, Tsuchihashi Z, Mauro DJ, Rowinsky EK.

J Clin Oncol. 2006 Oct 20;24(30):4914-21.PMID: 17050875 [PubMed - indexed for MEDLINE]Related articles

Systemic treatment of patients who have colorectal cancer and inflammatory bowel disease.

Goessling W, Mayer RJ.

Gastroenterol Clin North Am. 2006 Sep;35(3):713-27. Review.PMID: 16952747 [PubMed - indexed for MEDLINE]Related articles

Subcellular distribution of the TSC2 gene product tuberin in human airway smooth muscle cells is driven by multiple localization sequences and is cell-cycle dependent.

Clements D, Mayer RJ, Johnson SR.

Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L258-66. Epub 2006 Aug 11.PMID: 16905638 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase III trial of fluorouracil-based chemotherapy regimens plus radiotherapy in postoperative adjuvant rectal cancer: GI INT 0144.

Smalley SR, Benedetti JK, Williamson SK, Robertson JM, Estes NC, Maher T, Fisher B, Rich TA, Martenson JA, Kugler JW, Benson AB 3rd, Haller DG, Mayer RJ, Atkins JN, Cripps C, Pedersen J, Periman PO, Tanaka MS Jr, Leichman CG, Macdonald JS.

J Clin Oncol. 2006 Aug 1;24(22):3542-7.PMID: 16877719 [PubMed - indexed for MEDLINE]Related articles

Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803.

Meyerhardt JA, Heseltine D, Niedzwiecki D, Hollis D, Saltz LB, Mayer RJ, Thomas J, Nelson H, Whittom R, Hantel A, Schilsky RL, Fuchs CS.

J Clin Oncol. 2006 Aug 1;24(22):3535-41. Epub 2006 Jul 5.PMID: 16822843 [PubMed - indexed for MEDLINE]Related articles

Cancer and leukemia group B gastrointestinal cancer committee.

Goldberg RM, Niedzwiecki D, Bertagnolli M, Blackstock AW, Tepper JE, Mayer RJ.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 2):3589s-95s. Review.PMID: 16740790 [PubMed - indexed for MEDLINE]Related articlesFree article

Fifty years of clinical research by the leukemia committee of the cancer and leukemia group B.

Larson RA, Stone RM, Mayer RJ, Schiffer CA.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 2):3556s-63s. Review.PMID: 16740785 [PubMed - indexed for MEDLINE]Related articlesFree article

Phase I/II study of preoperative oxaliplatin, fluorouracil, and external-beam radiation therapy in patients with locally advanced rectal cancer: Cancer and Leukemia Group B 89901.

Cancer and Leukemia Group B 89901, Ryan DP, Niedzwiecki D, Hollis D, Mediema BE, Wadler S, Tepper JE, Goldberg RM, Mayer RJ.

J Clin Oncol. 2006 Jun 1;24(16):2557-62. Epub 2006 Apr 24.PMID: 16636336 [PubMed - indexed for MEDLINE]Related articles

Gankyrin: a new oncoprotein and regulator of pRb and p53.

Dawson S, Higashitsuji H, Wilkinson AJ, Fujita J, Mayer RJ.

Trends Cell Biol. 2006 May;16(5):229-33. Epub 2006 Apr 3.PMID: 16581249 [PubMed - indexed for MEDLINE]Related articles

Colorectal Cancer Screening Clinical Practice Guidelines.

Levin B, Barthel JS, Burt RW, David DS, Ford JM, Giardiello FM, Gruber SB, Halverson AL, Hamilton S, Kohlmann W, Ludwig KA, Lynch PM, Marino C, Martin EW Jr, Mayer RJ, Pasche B, Pirruccello SJ, Rajput A, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Winawer SJ.

J Natl Compr Canc Netw. 2006 Apr;4(4):384-420. No abstract available. PMID: 16569391 [PubMed - indexed for MEDLINE]Related articles

Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.

Cancer and Leukemia Group B 8461, Farag SS, Archer KJ, Mrózek K, Ruppert AS, Carroll AJ, Vardiman JW, Pettenati MJ, Baer MR, Qumsiyeh MB, Koduru PR, Ning Y, Mayer RJ, Stone RM, Larson RA, Bloomfield CD.

Blood. 2006 Jul 1;108(1):63-73. Epub 2006 Mar 7.PMID: 16522815 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481).

Kemeny NE, Niedzwiecki D, Hollis DR, Lenz HJ, Warren RS, Naughton MJ, Weeks JC, Sigurdson ER, Herndon JE 2nd, Zhang C, Mayer RJ.

J Clin Oncol. 2006 Mar 20;24(9):1395-403. Epub 2006 Feb 27.PMID: 16505413 [PubMed - indexed for MEDLINE]Related articles

Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001.

Redston M, Compton CC, Miedema BW, Niedzwiecki D, Dowell JM, Jewell SD, Fleshman JM, Bem J, Mayer RJ, Bertagnolli MM; Leukemia Group B Trial 80001.

J Clin Oncol. 2006 Feb 20;24(6):878-83. Epub 2006 Jan 17.PMID: 16418493 [PubMed - indexed for MEDLINE]Related articles

A phase II trial of irinotecan in patients with previously untreated advanced esophageal and gastric adenocarcinoma.

Enzinger PC, Kulke MH, Clark JW, Ryan DP, Kim H, Earle CC, Vincitore MM, Michelini AL, Mayer RJ, Fuchs CS.

Dig Dis Sci. 2005 Dec;50(12):2218-23.PMID: 16416165 [PubMed - indexed for MEDLINE]Related articles

Application of ubiquitin immunohistochemistry to the diagnosis of disease.

Lowe J, Hand N, Mayer RJ.

Methods Enzymol. 2005;399:86-119.PMID: 16338351 [PubMed - indexed for MEDLINE]Related articles

Clinical Cancer Advances 2005: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.

Herbst RS, Bajorin DF, Bleiberg H, Blum D, Hao D, Johnson BE, Ozols RF, Demetri GD, Ganz PA, Kris MG, Levin B, Markman M, Raghavan D, Reaman GH, Sawaya R, Schuchter LM, Sweetenham JW, Vahdat LT, Vokes EE, Winn RJ, Mayer RJ; American Society of Clinical Oncology.

J Clin Oncol. 2006 Jan 1;24(1):190-205. Epub 2005 Dec 2.PMID: 16326753 [PubMed - indexed for MEDLINE]Related articles