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Distinct phosphodiesterase-4D variants integrate into protein kinase A-based signaling complexes in cardiac and vascular myocytes.
Raymond DR, Carter RL, Ward CA, Maurice DH.
Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H263-71. Epub 2008 Dec 5.PMID: 19060129 [PubMed - indexed for MEDLINE]Related articles
Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions.
Wilson LS, Elbatarny HS, Crawley SW, Bennett BM, Maurice DH.
Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13650-5. Epub 2008 Aug 29.PMID: 18757735 [PubMed - indexed for MEDLINE]Related articlesFree article
Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion.
Raymond DR, Wilson LS, Carter RL, Maurice DH.
Cell Signal. 2007 Dec;19(12):2507-18. Epub 2007 Aug 15.PMID: 17884339 [PubMed - indexed for MEDLINE]Related articles
Both protein kinase A and exchange protein activated by cAMP coordinate adhesion of human vascular endothelial cells.
Netherton SJ, Sutton JA, Wilson LS, Carter RL, Maurice DH.
Circ Res. 2007 Oct 12;101(8):768-76. Epub 2007 Aug 23.PMID: 17717302 [PubMed - indexed for MEDLINE]Related articlesFree article
PI3Kgamma is required for PDE4, not PDE3, activity in subcellular microdomains containing the sarcoplasmic reticular calcium ATPase in cardiomyocytes.
Kerfant BG, Zhao D, Lorenzen-Schmidt I, Wilson LS, Cai S, Chen SR, Maurice DH, Backx PH.
Circ Res. 2007 Aug 17;101(4):400-8. Epub 2007 Jul 5.PMID: 17615371 [PubMed - indexed for MEDLINE]Related articlesFree article
Formation of extracellular matrix-digesting invadopodia by primary aortic smooth muscle cells.
Furmaniak-Kazmierczak E, Crawley SW, Carter RL, Maurice DH, Côté GP.
Circ Res. 2007 May 11;100(9):1328-36. Epub 2007 Apr 19.PMID: 17446433 [PubMed - indexed for MEDLINE]Related articlesFree article
cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.
Houslay MD, Baillie GS, Maurice DH.
Circ Res. 2007 Apr 13;100(7):950-66. Review.PMID: 17431197 [PubMed - indexed for MEDLINE]Related articlesFree article
Protein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivation.
Palmer D, Jimmo SL, Raymond DR, Wilson LS, Carter RL, Maurice DH.
J Biol Chem. 2007 Mar 30;282(13):9411-9. Epub 2007 Jan 25.PMID: 17255105 [PubMed - indexed for MEDLINE]Related articlesFree article
Adiponectin, ghrelin, and leptin differentially influence human platelet and human vascular endothelial cell functions: implication in obesity-associated cardiovascular diseases.
Elbatarny HS, Netherton SJ, Ovens JD, Ferguson AV, Maurice DH.
Eur J Pharmacol. 2007 Mar 8;558(1-3):7-13. Epub 2006 Dec 1.PMID: 17207790 [PubMed - indexed for MEDLINE]Related articles
Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation.
MacPherson JD, Gillespie TD, Dunkerley HA, Maurice DH, Bennett BM.
J Pharmacol Exp Ther. 2006 Apr;317(1):188-95. Epub 2005 Dec 5.PMID: 16330494 [PubMed - indexed for MEDLINE]Related articlesFree article
Vascular smooth muscle cell phenotype-dependent phosphodiesterase 4D short form expression: role of differential histone acetylation on cAMP-regulated function.
Tilley DG, Maurice DH.
Mol Pharmacol. 2005 Sep;68(3):596-605. Epub 2005 Jun 3.PMID: 15937214 [PubMed - indexed for MEDLINE]Related articlesFree article
Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex.
Elbatarny HS, Maurice DH.
Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E695-702. Epub 2005 May 10.PMID: 15886225 [PubMed - indexed for MEDLINE]Related articlesFree article
Mechanism of tissue-selective drug action in the cardiovascular system.
Barrett TD, Triggle DJ, Walker MJ, Maurice DH.
Mol Interv. 2005 Apr;5(2):84-93. Review.PMID: 15821157 [PubMed - indexed for MEDLINE]Related articlesFree article
Cyclic nucleotide phosphodiesterase-mediated integration of cGMP and cAMP signaling in cells of the cardiovascular system.
Maurice DH.
Front Biosci. 2005 May 1;10:1221-8. Review.PMID: 15769620 [PubMed - indexed for MEDLINE]Related articles
Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis.
Netherton SJ, Maurice DH.
Mol Pharmacol. 2005 Jan;67(1):263-72. Epub 2004 Oct 8.PMID: 15475573 [PubMed - indexed for MEDLINE]Related articlesFree article
Cardiovascular implications in the use of PDE5 inhibitor therapy.
Int J Impot Res. 2004 Jun;16 Suppl 1:S20-3. Review.PMID: 15224131 [PubMed - indexed for MEDLINE]Related articles
Dynamic regulation of cAMP signaling by cGMP in the cardiovascular system: roles of phosphodiesterase 2 and phosphodiesterase 3 enzymes.
Proc West Pharmacol Soc. 2003;46:32-6. Review. No abstract available. PMID: 14699879 [PubMed - indexed for MEDLINE]Related articles
Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system.
Maurice DH, Palmer D, Tilley DG, Dunkerley HA, Netherton SJ, Raymond DR, Elbatarny HS, Jimmo SL.
Mol Pharmacol. 2003 Sep;64(3):533-46. Review.PMID: 12920188 [PubMed - indexed for MEDLINE]Related articlesFree article
Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis.
Sage EH, Reed M, Funk SE, Truong T, Steadele M, Puolakkainen P, Maurice DH, Bassuk JA.
J Biol Chem. 2003 Sep 26;278(39):37849-57. Epub 2003 Jul 16.PMID: 12867428 [PubMed - indexed for MEDLINE]Related articlesFree article
Does sildenafil indirectly inhibit phosphodiesterase 3 in vascular smooth muscle?
Hypertension. 2003 Mar;41(3):e2. Epub 2003 Feb 10. No abstract available. PMID: 12623968 [PubMed - indexed for MEDLINE]Related articlesFree article
Vascular smooth muscle cell phosphodiesterase (PDE) 3 and PDE4 activities and levels are regulated by cyclic AMP in vivo.
Mol Pharmacol. 2002 Sep;62(3):497-506.PMID: 12181425 [PubMed - indexed for MEDLINE]Related articlesFree article
Reduced phosphodiesterase 3 activity and phosphodiesterase 3A level in synthetic vascular smooth muscle cells: implications for use of phosphodiesterase 3 inhibitors in cardiovascular tissues.
Dunkerley HA, Tilley DG, Palmer D, Liu H, Jimmo SL, Maurice DH.
Mol Pharmacol. 2002 May;61(5):1033-40.PMID: 11961121 [PubMed - indexed for MEDLINE]Related articlesFree article
Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease.
Netherton SJ, Jimmo SL, Palmer D, Tilley DG, Dunkerley HA, Raymond DR, Russell JC, Absher PM, Sage EH, Vernon RB, Maurice DH.
Diabetes. 2002 Apr;51(4):1194-200.PMID: 11916944 [PubMed - indexed for MEDLINE]Related articlesFree article
Dual expression and differential regulation of phosphodiesterase 3A and phosphodiesterase 3B in human vascular smooth muscle: implications for phosphodiesterase 3 inhibition in human cardiovascular tissues.
Palmer D, Maurice DH.
Mol Pharmacol. 2000 Aug;58(2):247-52.PMID: 10908291 [PubMed - indexed for MEDLINE]Related articlesFree article
Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling pathways. A potential mechanism allowing for the coordinated regulation of PDE4D activity and expression in cells.
Liu H, Palmer D, Jimmo SL, Tilley DG, Dunkerley HA, Pang SC, Maurice DH.
J Biol Chem. 2000 Aug 25;275(34):26615-24.PMID: 10851231 [PubMed - indexed for MEDLINE]Related articlesFree article
Aortic endothelial cell von Willebrand factor content, and circulating plasminogen activator inhibitor-1 are increased, but expression of endothelial leukocyte adhesion molecules is unchanged in insulin-dependent diabetic BB rats.
Ribau JC, Samis JA, Senis YA, Maurice DH, Giles AR, DeReske M, Absher PM, Hatton MW, Richardson M.
Atherosclerosis. 2000 Apr;149(2):331-42.PMID: 10729383 [PubMed - indexed for MEDLINE]Related articles
Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations.
Appleton SD, Chretien ML, McLaughlin BE, Vreman HJ, Stevenson DK, Brien JF, Nakatsu K, Maurice DH, Marks GS.
Drug Metab Dispos. 1999 Oct;27(10):1214-9.PMID: 10497150 [PubMed - indexed for MEDLINE]Related articlesFree article
Phosphorylation-mediated activation and translocation of the cyclic AMP-specific phosphodiesterase PDE4D3 by cyclic AMP-dependent protein kinase and mitogen-activated protein kinases. A potential mechanism allowing for the coordinated regulation of PDE4D activity and targeting.
Liu H, Maurice DH.
J Biol Chem. 1999 Apr 9;274(15):10557-65.PMID: 10187850 [PubMed - indexed for MEDLINE]Related articlesFree article
Expression of cyclic GMP-inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: differential subcellular localization and regulated expression by cyclic AMP.
Br J Pharmacol. 1998 Dec;125(7):1501-10.PMID: 9884079 [PubMed - indexed for MEDLINE]Related articlesFree article
Cyclic nucleotide-mediated regulation of vascular smooth muscle cell cyclic nucleotide phosphodiesterase activity. Selective effect of cyclic AMP.
Cell Biochem Biophys. 1998;29(1-2):35-47.PMID: 9631237 [PubMed - indexed for MEDLINE]Related articles
Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors.
Palmer D, Tsoi K, Maurice DH.
Circ Res. 1998 May 4;82(8):852-61.PMID: 9576105 [PubMed - indexed for MEDLINE]Related articlesFree article
Collaborative and reciprocal effects of ciliary neurotrophic factor and nerve growth factor on the neuronal phenotype of human neuroblastoma cells.
Zinman LH, Lawrance G, Wang W, Verge VM, Dow KE, Maurice DH, Richardson PM, Riopelle RJ.
J Neurochem. 1998 Apr;70(4):1411-20.PMID: 9523557 [PubMed - indexed for MEDLINE]Related articles
Cyclic AMP-mediated regulation of vascular smooth muscle cell cyclic AMP phosphodiesterase activity.
Rose RJ, Liu H, Palmer D, Maurice DH.
Br J Pharmacol. 1997 Sep;122(2):233-40.PMID: 9313930 [PubMed - indexed for MEDLINE]Related articlesFree article
The effects of truncations of the small subunit on m-calpain activity and heterodimer formation.
Elce JS, Davies PL, Hegadorn C, Maurice DH, Arthur JS.
Biochem J. 1997 Aug 15;326 ( Pt 1):31-8.PMID: 9337847 [PubMed - indexed for MEDLINE]Related articlesFree article
Vascular control mechanisms in penile erection: phylogeny and the inevitability of multiple and overlapping systems.
Adams MA, Banting JD, Maurice DH, Morales A, Heaton JP.
Int J Impot Res. 1997 Jun;9(2):85-91. Review.PMID: 9205875 [PubMed - indexed for MEDLINE]Related articles
Inhibition of the action of nitric oxide prodrugs by pyocyanin: mechanistic studies.
Hussain AS, Bozinovski J, Maurice DH, McLaughlin BE, Marks GS, Brien JF, Nakatsu K.
Can J Physiol Pharmacol. 1997 May;75(5):398-406.PMID: 9250373 [PubMed - indexed for MEDLINE]Related articles
Changes in the pattern of distribution of von Willebrand factor in rat aortic endothelial cells following thrombin generation in vivo.
Senis YA, Richardson M, Tinlin S, Maurice DH, Giles AR.
Br J Haematol. 1996 Apr;93(1):195-203.PMID: 8611460 [PubMed - indexed for MEDLINE]Related articles
Cell layer-specific expression of cyclic nucleotide phosphodiesterases in rat arteries: molecular cloning using isolated cell layers from paraformaldehyde-fixed tissues.
Maurice DH, Senis YA, Liu H, Giles AR, Horn EH.
J Pharmacol Toxicol Methods. 1995 Nov;34(3):175-85.PMID: 8573769 [PubMed - indexed for MEDLINE]Related articles
Selective sequestration of nitric oxide by subcellular components of vascular smooth muscle and platelets: relationship to nitric oxide stimulation of the soluble guanylyl cyclase.
Liu Z, Nakatsu K, Brien JF, Beaton ED, Marks GS, Maurice DH.
Can J Physiol Pharmacol. 1993 Dec;71(12):938-45.PMID: 7910110 [PubMed - indexed for MEDLINE]Related articles
Measurement of both cyclic [3H]AMP and cyclic [3H]GMP in cultured vascular smooth muscle cells labeled with [3H]hypoxanthine: use in studies of cardiovascular drugs.
Maurice DH, Lee RM, Haslam RJ.
Anal Biochem. 1993 Nov 15;215(1):110-7.PMID: 8297002 [PubMed - indexed for MEDLINE]Related articles
Identification of G alpha 11 as the phospholipase C-activating G-protein of turkey erythrocytes.
Maurice DH, Waldo GL, Morris AJ, Nicholas RA, Harden TK.
Biochem J. 1993 Mar 15;290 ( Pt 3):765-70.PMID: 8457205 [PubMed - indexed for MEDLINE]Related articlesFree article
Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle.
Maurice DH, Crankshaw D, Haslam RJ.
Eur J Pharmacol. 1991 Jan 10;192(2):235-42.PMID: 1851703 [PubMed - indexed for MEDLINE]Related articles
Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle.
Maurice DH, Haslam RJ.
Eur J Pharmacol. 1990 Dec 4;191(3):471-5.PMID: 1964912 [PubMed - indexed for MEDLINE]Related articles
Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP.
Mol Pharmacol. 1990 May;37(5):671-81.PMID: 2160060 [PubMed - indexed for MEDLINE]Related articles
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Proc Natl Acad Sci U S A. 2008 Sep 9; 105(36):13650-5.
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