PubMed

In vivo neurochemical profiling of rat brain by (1)H-[(13)C] NMR spectroscopy: cerebral energetics and glutamatergic/GABAergic neurotransmission.

van Eijsden P, Behar KL, Mason GF, Braun KP, de Graaf RA.

J Neurochem. 2009 Oct 10. [Epub ahead of print]PMID: 19818103 [PubMed - as supplied by publisher]Related articles

Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy.

Boumezbeur F, Mason GF, de Graaf RA, Behar KL, Cline GW, Shulman GI, Rothman DL, Petersen KF.

J Cereb Blood Flow Metab. 2009 Sep 30. [Epub ahead of print]PMID: 19794401 [PubMed - as supplied by publisher]Related articles

Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo.

Jiang L, Herzog RI, Mason GF, de Graaf RA, Rothman DL, Sherwin RS, Behar KL.

Diabetes. 2009 Jun;58(6):1266-74. Epub 2009 Mar 10.PMID: 19276443 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals.

Befroy DE, Petersen KF, Dufour S, Mason GF, Rothman DL, Shulman GI.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16701-6. Epub 2008 Oct 20.PMID: 18936488 [PubMed - indexed for MEDLINE]Related articlesFree article

It is time to take a stand for medical research and against terrorism targeting medical scientists.

Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R.

Biol Psychiatry. 2008 Apr 15;63(8):725-7. No abstract available. Erratum in: Biol Psychiatry. 2008 May 15;63(10):1001. PMID: 18371494 [PubMed - indexed for MEDLINE]Related articles

Glutamatergic and GABAergic neurotransmitter cycling and energy metabolism in rat cerebral cortex during postnatal development.

Chowdhury GM, Patel AB, Mason GF, Rothman DL, Behar KL.

J Cereb Blood Flow Metab. 2007 Dec;27(12):1895-907. Epub 2007 Apr 18.PMID: 17440492 [PubMed - indexed for MEDLINE]Related articles

Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients.

Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI.

Diabetes. 2007 May;56(5):1376-81. Epub 2007 Feb 7.PMID: 17287462 [PubMed - indexed for MEDLINE]Related articlesFree article

Get sober; stay sober.

Mason GF.

Brain. 2007 Jan;130(Pt 1):8-9. No abstract available. PMID: 17178741 [PubMed - indexed for MEDLINE]Related articlesFree article

Measurements of the anaplerotic rate in the human cerebral cortex using 13C magnetic resonance spectroscopy and [1-13C] and [2-13C] glucose.

Mason GF, Petersen KF, de Graaf RA, Shulman GI, Rothman DL.

J Neurochem. 2007 Jan;100(1):73-86. Epub 2006 Oct 31.PMID: 17076763 [PubMed - indexed for MEDLINE]Related articles

MR spectroscopy: its potential role for drug development for the treatment of psychiatric diseases.

Mason GF, Krystal JH.

NMR Biomed. 2006 Oct;19(6):690-701. Review.PMID: 16986118 [PubMed - indexed for MEDLINE]Related articles

The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women.

Amin Z, Mason GF, Cavus I, Krystal JH, Rothman DL, Epperson CN.

Pharmacol Biochem Behav. 2006 Aug;84(4):635-43. Epub 2006 Jul 24. Review.PMID: 16860856 [PubMed - indexed for MEDLINE]Related articles

Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study.

Epperson CN, Gueorguieva R, Czarkowski KA, Stiklus S, Sellers E, Krystal JH, Rothman DL, Mason GF.

Psychopharmacology (Berl). 2006 Jun;186(3):425-33. Epub 2006 May 3.PMID: 16724188 [PubMed - indexed for MEDLINE]Related articles

Increased brain monocarboxylic acid transport and utilization in type 1 diabetes.

Mason GF, Petersen KF, Lebon V, Rothman DL, Shulman GI.

Diabetes. 2006 Apr;55(4):929-34.PMID: 16567513 [PubMed - indexed for MEDLINE]Related articlesFree article

Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking.

Mason GF, Petrakis IL, de Graaf RA, Gueorguieva R, Guidone E, Coric V, Epperson CN, Rothman DL, Krystal JH.

Biol Psychiatry. 2006 Jan 1;59(1):85-93. Epub 2005 Nov 14.PMID: 16289397 [PubMed - indexed for MEDLINE]Related articles

Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy.

Sanacora G, Fenton LR, Fasula MK, Rothman DL, Levin Y, Krystal JH, Mason GF.

Biol Psychiatry. 2006 Feb 1;59(3):284-6. Epub 2005 Sep 1.PMID: 16139814 [PubMed - indexed for MEDLINE]Related articles

The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo.

Patel AB, de Graaf RA, Mason GF, Rothman DL, Shulman RG, Behar KL.

Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5588-93. Epub 2005 Apr 4.PMID: 15809416 [PubMed - indexed for MEDLINE]Related articlesFree article

Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy.

Epperson CN, O'Malley S, Czarkowski KA, Gueorguieva R, Jatlow P, Sanacora G, Rothman DL, Krystal JH, Mason GF.

Biol Psychiatry. 2005 Jan 1;57(1):44-8.PMID: 15607299 [PubMed - indexed for MEDLINE]Related articles

Impaired GABA neuronal response to acute benzodiazepine administration in panic disorder.

Goddard AW, Mason GF, Appel M, Rothman DL, Gueorguieva R, Behar KL, Krystal JH.

Am J Psychiatry. 2004 Dec;161(12):2186-93.PMID: 15569888 [PubMed - indexed for MEDLINE]Related articlesFree article

Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation.

Patel AB, de Graaf RA, Mason GF, Kanamatsu T, Rothman DL, Shulman RG, Behar KL.

J Cereb Blood Flow Metab. 2004 Sep;24(9):972-85.PMID: 15356418 [PubMed - indexed for MEDLINE]Related articles

Regional glucose metabolism and glutamatergic neurotransmission in rat brain in vivo.

de Graaf RA, Mason GF, Patel AB, Rothman DL, Behar KL.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12700-5. Epub 2004 Aug 13.PMID: 15310848 [PubMed - indexed for MEDLINE]Related articlesFree article

Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.

Sanacora G, Gueorguieva R, Epperson CN, Wu YT, Appel M, Rothman DL, Krystal JH, Mason GF.

Arch Gen Psychiatry. 2004 Jul;61(7):705-13.PMID: 15237082 [PubMed - indexed for MEDLINE]Related articlesFree article

Family psychopathology and magnitude of reductions in occipital cortex GABA levels in panic disorder.

Goddard AW, Mason GF, Rothman DL, Behar KL, Petroff OA, Krystal JH.

Neuropsychopharmacology. 2004 Mar;29(3):639-40. No abstract available. PMID: 14973435 [PubMed - indexed for MEDLINE]Related articlesFree article

Basic principles of metabolic modeling of NMR (13)C isotopic turnover to determine rates of brain metabolism in vivo.

Mason GF, Rothman DL.

Metab Eng. 2004 Jan;6(1):75-84.PMID: 14734257 [PubMed - indexed for MEDLINE]Related articles

Coupling of glutamatergic neurotransmission and neuronal glucose oxidation over the entire range of cerebral cortex activity.

Patel AB, De Graaf RA, Mason GF, Rothman DL, Shulman RG, Behar KL.

Ann N Y Acad Sci. 2003 Nov;1003:452-3. No abstract available. PMID: 14684486 [PubMed - indexed for MEDLINE]Related articles

In vivo 1H-[13C]-NMR spectroscopy of cerebral metabolism.

de Graaf RA, Mason GF, Patel AB, Behar KL, Rothman DL.

NMR Biomed. 2003 Oct-Nov;16(6-7):339-57. Review.PMID: 14679499 [PubMed - indexed for MEDLINE]Related articles

Magnetic resonance spectroscopy for studies of neurotransmission in vivo.

Mason GF.

Psychopharmacol Bull. 2003 Spring;37(2):26-40. Review.PMID: 14566212 [PubMed - indexed for MEDLINE]Related articlesFree article

Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT.

Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB.

Biol Psychiatry. 2003 Oct 15;54(8):792-9.PMID: 14550678 [PubMed - indexed for MEDLINE]Related articles

Increased cortical GABA concentrations in depressed patients receiving ECT.

Sanacora G, Mason GF, Rothman DL, Hyder F, Ciarcia JJ, Ostroff RB, Berman RM, Krystal JH.

Am J Psychiatry. 2003 Mar;160(3):577-9.PMID: 12611844 [PubMed - indexed for MEDLINE]Related articlesFree article

A comparison of (13)C NMR measurements of the rates of glutamine synthesis and the tricarboxylic acid cycle during oral and intravenous administration of [1-(13)C]glucose.

Mason GF, Falk Petersen K, de Graaf RA, Kanamatsu T, Otsuki T, Shulman GI, Rothman DL.

Brain Res Brain Res Protoc. 2003 Feb;10(3):181-90. Erratum in: Brain Res Brain Res Protoc. 2003 May;11(2):143. PMID: 12565689 [PubMed - indexed for MEDLINE]Related articles

Detection of [1,6-13C2]-glucose metabolism in rat brain by in vivo 1H-[13C]-NMR spectroscopy.

de Graaf RA, Brown PB, Mason GF, Rothman DL, Behar KL.

Magn Reson Med. 2003 Jan;49(1):37-46.PMID: 12509818 [PubMed - indexed for MEDLINE]Related articles

Graded image segmentation of brain tissue in the presence of inhomogeneous radio frequency fields.

Mason GF, Rothman DL.

Magn Reson Imaging. 2002 Jun;20(5):431-6.PMID: 12206869 [PubMed - indexed for MEDLINE]Related articles

Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study.

Epperson CN, Haga K, Mason GF, Sellers E, Gueorguieva R, Zhang W, Weiss E, Rothman DL, Krystal JH.

Arch Gen Psychiatry. 2002 Sep;59(9):851-8.PMID: 12215085 [PubMed - indexed for MEDLINE]Related articlesFree article

Regional cerebral blood flow and magnetic resonance spectroscopic imaging findings in diaschisis from stroke.

Chu WJ, Mason GF, Pan JW, Hetherington HP, Liu HG, San Pedro EC, Mountz JM.

Stroke. 2002 May;33(5):1243-8.PMID: 11988598 [PubMed - indexed for MEDLINE]Related articlesFree article

Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments.

Krystal JH, Sanacora G, Blumberg H, Anand A, Charney DS, Marek G, Epperson CN, Goddard A, Mason GF.

Mol Psychiatry. 2002;7 Suppl 1:S71-80. Review.PMID: 11986998 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.

Sanacora G, Mason GF, Rothman DL, Krystal JH.

Am J Psychiatry. 2002 Apr;159(4):663-5.PMID: 11925309 [PubMed - indexed for MEDLINE]Related articlesFree article

Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism.

Lebon V, Petersen KF, Cline GW, Shen J, Mason GF, Dufour S, Behar KL, Shulman GI, Rothman DL.

J Neurosci. 2002 Mar 1;22(5):1523-31.PMID: 11880482 [PubMed - indexed for MEDLINE]Related articlesFree article

Decrease in GABA synthesis rate in rat cortex following GABA-transaminase inhibition correlates with the decrease in GAD(67) protein.

Mason GF, Martin DL, Martin SB, Manor D, Sibson NR, Patel A, Rothman DL, Behar KL.

Brain Res. 2001 Sep 28;914(1-2):81-91.PMID: 11578600 [PubMed - indexed for MEDLINE]Related articles

Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy.

Goddard AW, Mason GF, Almai A, Rothman DL, Behar KL, Petroff OA, Charney DS, Krystal JH.

Arch Gen Psychiatry. 2001 Jun;58(6):556-61.PMID: 11386984 [PubMed - indexed for MEDLINE]Related articlesFree article

Impairment of GABAergic transmission in depression: new insights from neuroimaging studies.

Sanacora G, Mason GF, Krystal JH.

Crit Rev Neurobiol. 2000;14(1):23-45. Review.PMID: 11253954 [PubMed - indexed for MEDLINE]Related articles

In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during.

Sibson NR, Mason GF, Shen J, Cline GW, Herskovits AZ, Wall JE, Behar KL, Rothman DL, Shulman RG.

J Neurochem. 2001 Feb;76(4):975-89.PMID: 11181817 [PubMed - indexed for MEDLINE]Related articles

Differential increase in cerebral cortical glucose oxidative metabolism during rat postnatal development is greater in vivo than in vitro.

Novotny EJ Jr, Ariyan C, Mason GF, O'Reilly J, Haddad GG, Behar KL.

Brain Res. 2001 Jan 12;888(2):193-202.PMID: 11150475 [PubMed - indexed for MEDLINE]Related articles

Nonlinear determination of Michaelis-Menten kinetics with model evaluation through estimation of uncertainties.

Mason GF, Lai JC.

Metab Brain Dis. 2000 Jun;15(2):133-49.PMID: 11092580 [PubMed - indexed for MEDLINE]Related articles

Spectroscopic imaging of glutamate C4 turnover in human brain.

Pan JW, Stein DT, Telang F, Lee JH, Shen J, Brown P, Cline G, Mason GF, Shulman GI, Rothman DL, Hetherington HP.

Magn Reson Med. 2000 Nov;44(5):673-9.PMID: 11064400 [PubMed - indexed for MEDLINE]Related articles

Dependence of oxygen delivery on blood flow in rat brain: a 7 tesla nuclear magnetic resonance study.

Hyder F, Kennan RP, Kida I, Mason GF, Behar KL, Rothman D.

J Cereb Blood Flow Metab. 2000 Mar;20(3):485-98.PMID: 10724113 [PubMed - indexed for MEDLINE]Related articlesFree article

Measurement of the tricarboxylic acid cycle rate in human grey and white matter in vivo by 1H-[13C] magnetic resonance spectroscopy at 4.1T.

Mason GF, Pan JW, Chu WJ, Newcomer BR, Zhang Y, Orr R, Hetherington HP.

J Cereb Blood Flow Metab. 1999 Nov;19(11):1179-88.PMID: 10566964 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.

Sanacora G, Mason GF, Rothman DL, Behar KL, Hyder F, Petroff OA, Berman RM, Charney DS, Krystal JH.

Arch Gen Psychiatry. 1999 Nov;56(11):1043-7.PMID: 10565505 [PubMed - indexed for MEDLINE]Related articlesFree article

Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR.

Shen J, Petersen KF, Behar KL, Brown P, Nixon TW, Mason GF, Petroff OA, Shulman GI, Shulman RG, Rothman DL.

Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):8235-40.PMID: 10393978 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional energy metabolism: in vivo 13C-NMR spectroscopy evidence for coupling of cerebral glucose consumption and glutamatergic neuronalactivity.

Sibson NR, Shen J, Mason GF, Rothman DL, Behar KL, Shulman RG.

Dev Neurosci. 1998;20(4-5):321-30. Review.PMID: 9778568 [PubMed - indexed for MEDLINE]Related articles

Lateralization of human temporal lobe epilepsy by 31P NMR spectroscopic imaging at 4.1 T.

Chu WJ, Hetherington HP, Kuzniecky RI, Simor T, Mason GF, Elgavish GA.

Neurology. 1998 Aug;51(2):472-9.PMID: 9710021 [PubMed - indexed for MEDLINE]Related articles

A novel k-space trajectory measurement technique.

Zhang Y, Hetherington HP, Stokely EM, Mason GF, Twieg DB.

Magn Reson Med. 1998 Jun;39(6):999-1004.PMID: 9621924 [PubMed - indexed for MEDLINE]Related articles