PubMed

Deletion of protein tyrosine phosphatase 1b improves peripheral insulin resistance and vascular function in obese, leptin-resistant mice via reduced oxidant tone.

Ali MI, Ketsawatsomkron P, Belin de Chantemele EJ, Mintz JD, Muta K, Salet C, Black SM, Tremblay ML, Fulton DJ, Marrero MB, Stepp DW.

Circ Res. 2009 Nov 6;105(10):1013-22. Epub 2009 Sep 24.PMID: 19797171 [PubMed - in process]Related articles

An Alpha7 Nicotinic Acetylcholine Receptor-Selective Agonist Reduces Weight Gain and Metabolic Changes in a Mouse Model of Diabetes.

Marrero MB, Lucas R, Salet C, Hauser TA, Mazurov A, Lippiello PM, Bencherif M.

J Pharmacol Exp Ther. 2009 Sep 28. [Epub ahead of print]PMID: 19786623 [PubMed - as supplied by publisher]Related articlesFree article

Protein tyrosine phosphatase 1B, a major regulator of leptin-mediated control of cardiovascular function.

Belin de Chantemèle EJ, Muta K, Mintz J, Tremblay ML, Marrero MB, Fulton DJ, Stepp DW.

Circulation. 2009 Sep 1;120(9):753-63. Epub 2009 Aug 17.PMID: 19687357 [PubMed - indexed for MEDLINE]Related articles

Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: central role for JAK2 activation of STAT3 and NF-kappaB.

Marrero MB, Bencherif M.

Brain Res. 2009 Feb 23;1256:1-7. Epub 2008 Nov 27.PMID: 19063868 [PubMed - indexed for MEDLINE]Related articles

Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase.

Zhang Q, Malik P, Pandey D, Gupta S, Jagnandan D, Belin de Chantemele E, Banfi B, Marrero MB, Rudic RD, Stepp DW, Fulton DJ.

Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1627-33. Epub 2008 Jun 12.PMID: 18556569 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II-induced signaling pathways in diabetes.

Marrero MB, Fulton D, Stepp D, Stern DM.

Curr Diabetes Rev. 2005 May;1(2):197-202. Review.PMID: 18220595 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation.

Banes-Berceli AK, Ketsawatsomkron P, Ogbi S, Patel B, Pollock DM, Marrero MB.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1291-9. Epub 2007 May 25.PMID: 17526654 [PubMed - indexed for MEDLINE]Related articlesFree article

P2 receptor regulation of [Ca2+]i in cultured mouse mesangial cells.

Rivera I, Zhang S, Fuller BS, Edwards B, Seki T, Wang MH, Marrero MB, Inscho EW.

Am J Physiol Renal Physiol. 2007 May;292(5):F1380-9. Epub 2007 Jan 9.PMID: 17213463 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel mechanism of activation of NADPH oxidase 5. calcium sensitization via phosphorylation.

Jagnandan D, Church JE, Banfi B, Stuehr DJ, Marrero MB, Fulton DJ.

J Biol Chem. 2007 Mar 2;282(9):6494-507. Epub 2006 Dec 12.PMID: 17164239 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the JAK/STAT signaling pathway in diabetic nephropathy.

Marrero MB, Banes-Berceli AK, Stern DM, Eaton DC.

Am J Physiol Renal Physiol. 2006 Apr;290(4):F762-8. Review.PMID: 16527921 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of endothelin-1 activation of MAP kinases in neonatal pulmonary vascular smooth muscle.

Barman SA, Marrero MB.

Lung. 2005 Nov-Dec;183(6):425-39.PMID: 16465602 [PubMed - indexed for MEDLINE]Related articles

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells.

Banes-Berceli AK, Shaw S, Ma G, Brands M, Eaton DC, Stern DM, Fulton D, Caldwell RW, Marrero MB.

Am J Physiol Renal Physiol. 2006 Jul;291(1):F116-21. Epub 2006 Jan 31.PMID: 16449352 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1 activation of JAK2 in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species.

Banes-Berceli AK, Ogobi S, Tawfik A, Patel B, Shirley A, Pollock DM, Fulton D, Marrero MB.

Vascul Pharmacol. 2005 Nov;43(5):310-9.PMID: 16290054 [PubMed - indexed for MEDLINE]Related articles

Introduction to JAK/STAT signaling and the vasculature.

Marrero MB.

Vascul Pharmacol. 2005 Nov;43(5):307-9. Epub 2005 Nov 2. No abstract available. PMID: 16263337 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2.

Tawfik A, Jin L, Banes-Berceli AK, Caldwell RB, Ogbi S, Shirley A, Barber D, Catravas JD, Stern DM, Fulton D, Caldwell RW, Marrero MB.

Vascul Pharmacol. 2005 Nov;43(5):320-6. Epub 2005 Oct 27.PMID: 16257269 [PubMed - indexed for MEDLINE]Related articles

Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury.

Hwang YC, Shaw S, Kaneko M, Redd H, Marrero MB, Ramasamy R.

FASEB J. 2005 May;19(7):795-7. Epub 2005 Mar 3.PMID: 15746188 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin.

Banes AK, Shaw SM, Tawfik A, Patel BP, Ogbi S, Fulton D, Marrero MB.

Am J Physiol Cell Physiol. 2005 Apr;288(4):C805-12. Epub 2004 Dec 15.PMID: 15601754 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II-induced insulin resistance and protein tyrosine phosphatases.

Marrero MB, Fulton D, Stepp D, Stern DM.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2009-13. Epub 2004 Jul 22. Review.PMID: 15271787 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance does not diminish eNOS expression, phosphorylation, or binding to HSP-90.

Fulton D, Harris MB, Kemp BE, Venema RC, Marrero MB, Stepp DW.

Am J Physiol Heart Circ Physiol. 2004 Dec;287(6):H2384-93. Epub 2004 Jul 22.PMID: 15271670 [PubMed - indexed for MEDLINE]Related articlesFree article

The neuroprotective effect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a novel alpha7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase.

Marrero MB, Papke RL, Bhatti BS, Shaw S, Bencherif M.

J Pharmacol Exp Ther. 2004 Apr;309(1):16-27. Epub 2004 Jan 13.PMID: 14722323 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli.

Banes AK, Shaw S, Jenkins J, Redd H, Amiri F, Pollock DM, Marrero MB.

Am J Physiol Renal Physiol. 2004 Apr;286(4):F653-9. Epub 2003 Dec 16.PMID: 14678947 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II blocks nicotine-mediated neuroprotection against beta-amyloid (1-42) via activation of the tyrosine phosphatase SHP-1.

Shaw S, Bencherif M, Marrero MB.

J Neurosci. 2003 Dec 3;23(35):11224-8.PMID: 14657181 [PubMed - indexed for MEDLINE]Related articlesFree article

S100B-RAGE-mediated augmentation of angiotensin II-induced activation of JAK2 in vascular smooth muscle cells is dependent on PLD2.

Shaw SS, Schmidt AM, Banes AK, Wang X, Stern DM, Marrero MB.

Diabetes. 2003 Sep;52(9):2381-8.PMID: 12941779 [PubMed - indexed for MEDLINE]Related articlesFree article

VEGF differentially activates STAT3 in microvascular endothelial cells.

Bartoli M, Platt D, Lemtalsi T, Gu X, Brooks SE, Marrero MB, Caldwell RB.

FASEB J. 2003 Aug;17(11):1562-4. Epub 2003 Jun 17.PMID: 12824281 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose augments the angiotensin II-induced activation of JAK2 in vascular smooth muscle cells via the polyol pathway.

Shaw S, Wang X, Redd H, Alexander GD, Isales CM, Marrero MB.

J Biol Chem. 2003 Aug 15;278(33):30634-41. Epub 2003 May 30.PMID: 12777386 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells.

Wang X, Shaw S, Amiri F, Eaton DC, Marrero MB.

Diabetes. 2002 Dec;51(12):3505-9.PMID: 12453907 [PubMed - indexed for MEDLINE]Related articlesFree article

Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid.

Shaw S, Bencherif M, Marrero MB.

J Biol Chem. 2002 Nov 22;277(47):44920-4. Epub 2002 Sep 18.PMID: 12244045 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II stimulates calcineurin activity in proximal tubule epithelia through AT-1 receptor-mediated tyrosine phosphorylation of the PLC-gamma1 isoform.

Lea JP, Jin SG, Roberts BR, Shuler MS, Marrero MB, Tumlin JA.

J Am Soc Nephrol. 2002 Jul;13(7):1750-6.PMID: 12089370 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose.

Amiri F, Shaw S, Wang X, Tang J, Waller JL, Eaton DC, Marrero MB.

Kidney Int. 2002 May;61(5):1605-16.PMID: 11967010 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor activates STAT proteins in aortic endothelial cells.

Bartoli M, Gu X, Tsai NT, Venema RC, Brooks SE, Marrero MB, Caldwell RB.

J Biol Chem. 2000 Oct 27;275(43):33189-92.PMID: 10961983 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-4 mediates STAT6 activation in 3T3-L1 preadipocytes but not adipocytes.

Deng J, Hua K, Lesser SS, Greiner AH, Walter AW, Marrero MB, Harp JB.

Biochem Biophys Res Commun. 2000 Jan 19;267(2):516-20.PMID: 10631093 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia enhances angiotensin II-induced janus-activated kinase/STAT signaling in vascular smooth muscle cells.

Amiri F, Venema VJ, Wang X, Ju H, Venema RC, Marrero MB.

J Biol Chem. 1999 Nov 5;274(45):32382-6.PMID: 10542280 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial nitric oxide synthase interactions with G-protein-coupled receptors.

Marrero MB, Venema VJ, Ju H, He H, Liang H, Caldwell RB, Venema RC.

Biochem J. 1999 Oct 15;343 Pt 2:335-40.PMID: 10510297 [PubMed - indexed for MEDLINE]Related articlesFree article

Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src.

He H, Venema VJ, Gu X, Venema RC, Marrero MB, Caldwell RB.

J Biol Chem. 1999 Aug 27;274(35):25130-5.PMID: 10455194 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of angiotensin II-induced phosphorylation of STAT3 in vascular smooth muscle cells.

Liang H, Venema VJ, Wang X, Ju H, Venema RC, Marrero MB.

J Biol Chem. 1999 Jul 9;274(28):19846-51.PMID: 10391929 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunolocalization of phospholipase C isoforms in rat kidney.

Lea JP, Ertoy D, Hollis JL, Marrero MB, Sands JM.

Kidney Int. 1998 Nov;54(5):1484-90.PMID: 9844124 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition by the JAK/STAT pathway of IFNgamma- and LPS-stimulated nitric oxide synthase induction in vascular smooth muscle cells.

Marrero MB, Venema VJ, He H, Caldwell RB, Venema RC.

Biochem Biophys Res Commun. 1998 Nov 18;252(2):508-12.PMID: 9826561 [PubMed - indexed for MEDLINE]Related articles

Regulation of angiotensin II-induced JAK2 tyrosine phosphorylation: roles of SHP-1 and SHP-2.

Marrero MB, Venema VJ, Ju H, Eaton DC, Venema RC.

Am J Physiol. 1998 Nov;275(5 Pt 1):C1216-23.PMID: 9814969 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II-induced tyrosine phosphorylation of signal transducers and activators of transcription 1 is regulated by Janus-activated kinase 2 and Fyn kinases and mitogen-activated protein kinase phosphatase 1.

Venema RC, Venema VJ, Eaton DC, Marrero MB.

J Biol Chem. 1998 Nov 13;273(46):30795-800.PMID: 9804857 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory interactions of the bradykinin B2 receptor with endothelial nitric-oxide synthase.

Ju H, Venema VJ, Marrero MB, Venema RC.

J Biol Chem. 1998 Sep 11;273(37):24025-9.PMID: 9727019 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of p130Cas by angiotensin II is dependent on c-Src, intracellular Ca2+, and protein kinase C.

Sayeski PP, Ali MS, Harp JB, Marrero MB, Bernstein KE.

Circ Res. 1998 Jun 29;82(12):1279-88.PMID: 9648724 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of fatty acid synthase in cell lines derived from experimental mammary tumors.

Hennigar RA, Pochet M, Hunt DA, Lukacher AE, Venema VJ, Seal E, Marrero MB.

Biochim Biophys Acta. 1998 May 20;1392(1):85-100.PMID: 9593836 [PubMed - indexed for MEDLINE]Related articles

Bradykinin stimulates the tyrosine phosphorylation and bradykinin B2 receptor association of phospholipase C gamma 1 in vascular endothelial cells.

Venema VJ, Ju H, Sun J, Eaton DC, Marrero MB, Venema RC.

Biochem Biophys Res Commun. 1998 May 8;246(1):70-5.PMID: 9600070 [PubMed - indexed for MEDLINE]Related articles

Erythropoietin receptor-operated Ca2+ channels: activation by phospholipase C-gamma 1.

Marrero MB, Venema RC, Ma H, Ling BN, Eaton DC.

Kidney Int. 1998 May;53(5):1259-68.PMID: 9573541 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II-induced association of phospholipase Cgamma1 with the G-protein-coupled AT1 receptor.

Venema RC, Ju H, Venema VJ, Schieffer B, Harp JB, Ling BN, Eaton DC, Marrero MB.

J Biol Chem. 1998 Mar 27;273(13):7703-8.PMID: 9516477 [PubMed - indexed for MEDLINE]Related articlesFree article

New insights into the cellular signaling of seven transmembrane receptors: the role of tyrosine phosphorylation.

Bernstein KE, Ali MS, Sayeski PP, Semeniuk D, Marrero MB.

Lab Invest. 1998 Jan;78(1):3-7. Review. No abstract available. PMID: 9461117 [PubMed - indexed for MEDLINE]Related articles

Role of Janus kinase/signal transducer and activator of transcription and mitogen-activated protein kinase cascades in angiotensin II- and platelet-derived growth factor-induced vascular smooth muscle cell proliferation.

Marrero MB, Schieffer B, Li B, Sun J, Harp JB, Ling BN.

J Biol Chem. 1997 Sep 26;272(39):24684-90.PMID: 9305939 [PubMed - indexed for MEDLINE]Related articlesFree article

Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor.

Ali MS, Sayeski PP, Dirksen LB, Hayzer DJ, Marrero MB, Bernstein KE.

J Biol Chem. 1997 Sep 12;272(37):23382-8.PMID: 9287353 [PubMed - indexed for MEDLINE]Related articlesFree article

Caveolin-1 detergent solubility and association with endothelial nitric oxide synthase is modulated by tyrosine phosphorylation.

Venema VJ, Zou R, Ju H, Marrero MB, Venema RC.

Biochem Biophys Res Commun. 1997 Jul 9;236(1):155-61.PMID: 9223444 [PubMed - indexed for MEDLINE]Related articles

G protein-coupled receptors control vascular smooth muscle cell proliferation via pp60c-src and p21ras.

Schieffer B, Drexler H, Ling BN, Marrero MB.

Am J Physiol. 1997 Jun;272(6 Pt 1):C2019-30.PMID: 9227431 [PubMed - indexed for MEDLINE]Related articles