PubMed

Cardiovascular side effects of antiobesity drugs: a yellow flag in the race to safe pharmacotherapy for obesity.

Mark AL.

Circulation. 2009 Sep 1;120(9):719-21. Epub 2009 Aug 17. No abstract available. PMID: 19687353 [PubMed - indexed for MEDLINE]Related articles

Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney.

Mark AL, Agassandian K, Morgan DA, Liu X, Cassell MD, Rahmouni K.

Hypertension. 2009 Feb;53(2):375-80. Epub 2008 Dec 22.PMID: 19103999 [PubMed - indexed for MEDLINE]Related articles

Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin.

Rahmouni K, Sigmund CD, Haynes WG, Mark AL.

Diabetes. 2009 Mar;58(3):536-42. Epub 2008 Dec 9.PMID: 19066310 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary therapy for obesity: an emperor with no clothes.

Mark AL.

Hypertension. 2008 Jun;51(6):1426-34; discussion 1434. Epub 2008 May 12. Review. No abstract available. PMID: 18474832 [PubMed - indexed for MEDLINE]Related articlesFree article

Weight reduction for treatment of obesity-associated hypertension: nuances and challenges.

Mark AL.

Curr Hypertens Rep. 2007 Nov;9(5):368-72. Review.PMID: 18177582 [PubMed - indexed for MEDLINE]Related articles

NHS restructuring: Consider social anthropology.

Mark AL.

BMJ. 2007 Jul 28;335(7612):172. No abstract available. PMID: 17656518 [PubMed - indexed for MEDLINE]Related articles

Dietary therapy for obesity is a failure and pharmacotherapy is the future: a point of view.

Mark AL.

Clin Exp Pharmacol Physiol. 2006 Sep;33(9):857-62.PMID: 16922821 [PubMed - indexed for MEDLINE]Related articles

Role of selective leptin resistance in diet-induced obesity hypertension.

Rahmouni K, Morgan DA, Morgan GM, Mark AL, Haynes WG.

Diabetes. 2005 Jul;54(7):2012-8.PMID: 15983201 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of leptin actions in obesity: two concepts with cardiovascular implications.

Mark AL, Correia ML, Rahmouni K, Haynes WG.

Clin Exp Hypertens. 2004 Oct-Nov;26(7-8):629-36. Review.PMID: 15702617 [PubMed - indexed for MEDLINE]Related articles

Obesity-associated hypertension: new insights into mechanisms.

Rahmouni K, Correia ML, Haynes WG, Mark AL.

Hypertension. 2005 Jan;45(1):9-14. Epub 2004 Dec 6. Review.PMID: 15583075 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic PI3K and MAPK differentially mediate regional sympathetic activation to insulin.

Rahmouni K, Morgan DA, Morgan GM, Liu X, Sigmund CD, Mark AL, Haynes WG.

J Clin Invest. 2004 Sep;114(5):652-8.PMID: 15343383 [PubMed - indexed for MEDLINE]Related articlesFree article

NHS direct: managing demand for primary care?

Mark AL, Shepherd ID.

Int J Health Plann Manage. 2004 Jan-Mar;19(1):79-91.PMID: 15061291 [PubMed - indexed for MEDLINE]Related articles

Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesity.

Rahmouni K, Mark AL, Haynes WG, Sigmund CD.

Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E891-5. Epub 2004 Jan 28.PMID: 14749209 [PubMed - indexed for MEDLINE]Related articlesFree article

How has NHS Direct changed primary care provision?

Mark AL, Shepherd ID.

J Telemed Telecare. 2003;9 Suppl 1:S57-9.PMID: 12952725 [PubMed - indexed for MEDLINE]Related articles

Role of melanocortin-4 receptors in mediating renal sympathoactivation to leptin and insulin.

Rahmouni K, Haynes WG, Morgan DA, Mark AL.

J Neurosci. 2003 Jul 9;23(14):5998-6004.PMID: 12853417 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular mechanisms involved in leptin regulation of sympathetic outflow.

Rahmouni K, Haynes WG, Morgan DA, Mark AL.

Hypertension. 2003 Mar;41(3 Pt 2):763-7. Epub 2002 Dec 16.PMID: 12623993 [PubMed - indexed for MEDLINE]Related articlesFree article

A leptin-sympathetic-leptin feedback loop: potential implications for regulation of arterial pressure and body fat.

Mark AL, Rahmouni K, Correia M, Haynes WG.

Acta Physiol Scand. 2003 Mar;177(3):345-9. Review.PMID: 12609005 [PubMed - indexed for MEDLINE]Related articles

Ambulatory practice module debuts at Carver College of Medicine.

Ephgrave KS, Mark AL.

Iowa Med. 2002 Sep-Oct;92(5):13. No abstract available. PMID: 12369215 [PubMed - indexed for MEDLINE]Related articles

Pharmacotherapy of obesity: lessons from clinical trials in hypertension.

Haynes WG, Mark AL.

J Hypertens. 2002 Sep;20(9):1731-5. Review. No abstract available. PMID: 12195112 [PubMed - indexed for MEDLINE]Related articles

Differential modulation of leptin-induced sympathoexcitation by baroreflex activation.

Hausberg M, Morgan DA, Chapleau MA, Sivitz WI, Mark AL, Haynes WG.

J Hypertens. 2002 Aug;20(8):1633-41.PMID: 12172326 [PubMed - indexed for MEDLINE]Related articles

Leptin potentiates thermogenic sympathetic responses to hypothermia: a receptor-mediated effect.

Hausberg M, Morgan DA, Mitchell JL, Sivitz WI, Mark AL, Haynes WG.

Diabetes. 2002 Aug;51(8):2434-40.PMID: 12145155 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications.

Mark AL, Correia ML, Rahmouni K, Haynes WG.

J Hypertens. 2002 Jul;20(7):1245-50. Review.PMID: 12131511 [PubMed - indexed for MEDLINE]Related articles

Nurses as NHS gatekeepers. Nurses tend to use social rather than medical model of care.

Mark AL.

BMJ. 2002 Jul 20;325(7356):165. No abstract available. PMID: 12130619 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling metabolism and coupling leptin to cardiovascular disease.

Mark AL, Sivitz WI.

Arterioscler Thromb Vasc Biol. 2002 Jun 1;22(6):881-3. Review. No abstract available. PMID: 12067892 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiovascular and sympathetic effects of leptin.

Rahmouni K, Haynes WG, Mark AL.

Curr Hypertens Rep. 2002 Apr;4(2):119-25. Review.PMID: 11884267 [PubMed - indexed for MEDLINE]Related articles

Selective resistance to central neural administration of leptin in agouti obese mice.

Rahmouni K, Haynes WG, Morgan DA, Mark AL.

Hypertension. 2002 Feb;39(2 Pt 2):486-90.PMID: 11882595 [PubMed - indexed for MEDLINE]Related articlesFree article

Hemodynamic consequences of neuropeptide Y-induced obesity.

Correia ML, Morgan DA, Sivitz WI, Mark AL, Haynes WG.

Am J Hypertens. 2002 Feb;15(2 Pt 1):137-42.PMID: 11865825 [PubMed - indexed for MEDLINE]Related articles

The concept of selective leptin resistance: evidence from agouti yellow obese mice.

Correia ML, Haynes WG, Rahmouni K, Morgan DA, Sivitz WI, Mark AL.

Diabetes. 2002 Feb;51(2):439-42.PMID: 11812752 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinician scientist training program: a proposal for training medical students in clinical research.

Mark AL, Kelch RP.

J Investig Med. 2001 Nov;49(6):486-90.PMID: 11730083 [PubMed - indexed for MEDLINE]Related articles

Does leptin stimulate nitric oxide to oppose the effects of sympathetic activation?

Mitchell JL, Morgan DA, Correia ML, Mark AL, Sivitz WI, Haynes WG.

Hypertension. 2001 Nov;38(5):1081-6.PMID: 11711501 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure.

Correia ML, Morgan DA, Mitchell JL, Sivitz WI, Mark AL, Haynes WG.

Hypertension. 2001 Sep;38(3):384-8.PMID: 11566909 [PubMed - indexed for MEDLINE]Related articlesFree article

Does leptin cause functional peripheral sympatholysis?

Jalali A, Morgan DA, Sivitz WI, Correia ML, Mark AL, Haynes WG.

Am J Hypertens. 2001 Jul;14(7 Pt 1):615-8.PMID: 11465643 [PubMed - indexed for MEDLINE]Related articles

Leptin acts in the central nervous system to produce dose-dependent changes in arterial pressure.

Correia ML, Morgan DA, Sivitz WI, Mark AL, Haynes WG.

Hypertension. 2001 Mar;37(3):936-42.PMID: 11244021 [PubMed - indexed for MEDLINE]Related articlesFree article

Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice.

Mark AL, Shaffer RA, Correia ML, Morgan DA, Sigmund CD, Haynes WG.

J Hypertens. 1999 Dec;17(12 Pt 2):1949-53.PMID: 10703894 [PubMed - indexed for MEDLINE]Related articles

Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic.

Haynes WG, Morgan DA, Djalali A, Sivitz WI, Mark AL.

Hypertension. 1999 Jan;33(1 Pt 2):542-7.PMID: 9931162 [PubMed - indexed for MEDLINE]Related articlesFree article

State-of-the-art-lecture: Obesity-induced hypertension: new concepts from the emerging biology of obesity.

Mark AL, Correia M, Morgan DA, Shaffer RA, Haynes WG.

Hypertension. 1999 Jan;33(1 Pt 2):537-41. Review.PMID: 9931161 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperinsulinemia produces cardiac vagal withdrawal and nonuniform sympathetic activation in normal subjects.

Van De Borne P, Hausberg M, Hoffman RP, Mark AL, Anderson EA.

Am J Physiol. 1999 Jan;276(1 Pt 2):R178-83.PMID: 9887192 [PubMed - indexed for MEDLINE]Related articlesFree article

Short tandem repeat polymorphic markers for the rat genome from marker-selected libraries.

Walder RY, Garrett MR, McClain AM, Beck GE, Brennan TM, Kramer NA, Kanis AB, Mark AL, Rapp JP, Sheffield VC.

Mamm Genome. 1998 Dec;9(12):1013-21.PMID: 9880670 [PubMed - indexed for MEDLINE]Related articles

Sympathetic nerve activity and insulin sensitivity in normotensive offspring of hypertensive parents.

Hausberg M, Sinkey CA, Mark AL, Hoffman RP, Anderson EA.

Am J Hypertens. 1998 Nov;11(11 Pt 1):1312-20.PMID: 9832174 [PubMed - indexed for MEDLINE]Related articles

Risk stratification with pre-hospital discharge exercise technetium-99m sestamibi myocardial tomography in men after acute myocardial infarction.

Stratmann HG, Mark AL, Amato M, Wittry MD, Younis LT.

Am Heart J. 1998 Jul;136(1):87-93.PMID: 9665223 [PubMed - indexed for MEDLINE]Related articles

The treatment of heart failure: the role of neurohumoral activation.

Middlekauff HR, Mark AL.

Intern Med. 1998 Feb;37(2):112-22. Review.PMID: 9550589 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage of infantile Bartter syndrome with sensorineural deafness to chromosome 1p.

Brennan TM, Landau D, Shalev H, Lamb F, Schutte BC, Walder RY, Mark AL, Carmi R, Sheffield VC.

Am J Hum Genet. 1998 Feb;62(2):355-61.PMID: 9463315 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiovascular consequences of obesity: role of leptin.

Haynes WG, Morgan DA, Walsh SA, Sivitz WI, Mark AL.

Clin Exp Pharmacol Physiol. 1998 Jan;25(1):65-9. Review.PMID: 9493562 [PubMed - indexed for MEDLINE]Related articles

Sympathetic and cardiorenal actions of leptin.

Haynes WG, Sivitz WI, Morgan DA, Walsh SA, Mark AL.

Hypertension. 1997 Sep;30(3 Pt 2):619-23. Review.PMID: 9322991 [PubMed - indexed for MEDLINE]Related articlesFree article

Familial hypomagnesemia maps to chromosome 9q, not to the X chromosome: genetic linkage mapping and analysis of a balanced translocation breakpoint.

Walder RY, Shalev H, Brennan TM, Carmi R, Elbedour K, Scott DA, Hanauer A, Mark AL, Patil S, Stone EM, Sheffield VC.

Hum Mol Genet. 1997 Sep;6(9):1491-7.PMID: 9285786 [PubMed - indexed for MEDLINE]Related articlesFree article

Receptor-mediated regional sympathetic nerve activation by leptin.

Haynes WG, Morgan DA, Walsh SA, Mark AL, Sivitz WI.

J Clin Invest. 1997 Jul 15;100(2):270-8.PMID: 9218503 [PubMed - indexed for MEDLINE]Related articlesFree article

Sympathetic and vascular effects of short-term passive smoke exposure in healthy nonsmokers.

Hausberg M, Mark AL, Winniford MD, Brown RE, Somers VK.

Circulation. 1997 Jul 1;96(1):282-7.PMID: 9236446 [PubMed - indexed for MEDLINE]Related articles

Effects of alcohol on sympathetic activity, hemodynamics, and chemoreflex sensitivity.

van de Borne P, Mark AL, Montano N, Mion D, Somers VK.

Hypertension. 1997 Jun;29(6):1278-83.PMID: 9180629 [PubMed - indexed for MEDLINE]Related articlesFree article

Contrasting autonomic and hemodynamic effects of insulin in healthy elderly versus young subjects.

Hausberg M, Hoffman RP, Somers VK, Sinkey CA, Mark AL, Anderson EA.

Hypertension. 1997 Mar;29(3):700-5.PMID: 9052884 [PubMed - indexed for MEDLINE]Related articlesFree article

The sympathetic nervous system in hypertension: a potential long-term regulator of arterial pressure.

Mark AL.

J Hypertens Suppl. 1996 Dec;14(5):S159-65. Review.PMID: 9120673 [PubMed - indexed for MEDLINE]Related articles