PubMed

Direct fibrinolytic agents: biochemical attributes, pre-clinical foundation and clinical potential.

Marder VJ, Novokhatny V.

J Thromb Haemost. 2009 Nov 23. [Epub ahead of print]PMID: 19943877 [PubMed - as supplied by publisher]

Thrombolytic therapy for deep vein thrombosis: potential application of plasmin.

Marder VJ.

Thromb Res. 2009;123 Suppl 4:S56-61. Review.PMID: 19303506 [PubMed - indexed for MEDLINE]Related articles

On the significance of marginally low von Willebrand factor.

Onundarson PT, Gudmundsdottir BR, Marder VJ.

Thromb Haemost. 2008 Dec;100(6):1213-4. No abstract available. PMID: 19132256 [PubMed - indexed for MEDLINE]Related articles

Pre-clinical studies of plasmin: superior benefit-to-risk ratio of plasmin compared to tissue plasminogen activator.

Marder VJ.

Thromb Res. 2008;122 Suppl 3:S9-S15. Epub 2008 Aug 22. Review.PMID: 18722003 [PubMed - indexed for MEDLINE]Related articles

A first-in-human phase I trial of locally delivered human plasmin for hemodialysis graft occlusion.

Shlansky-Goldberg RD, Matsumoto AH, Baumbach GA, Siegel JB, Raabe RD, Murphy TP, Deng C, Ray Dawkins J, Marder VJ.

J Thromb Haemost. 2008 Jun;6(6):944-50. Epub 2008 Apr 2.PMID: 18384651 [PubMed - indexed for MEDLINE]Related articlesFree article

Middle cerebral artery occlusion in the rabbit using selective angiography: application for assessment of thrombolysis.

Jahan R, Stewart D, Vinters HV, Yong W, Vinuela F, Vandeberg P, Marder VJ.

Stroke. 2008 May;39(5):1613-5. Epub 2008 Mar 13.PMID: 18340097 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk of excessive bleeding associated with marginally low von Willebrand factor and mild platelet dysfunction.

Gudmundsdottir BR, Marder VJ, Onundarson PT.

J Thromb Haemost. 2007 Feb;5(2):274-81. Epub 2006 Nov 29.PMID: 17137472 [PubMed - indexed for MEDLINE]Related articles

Magnesium sulfate neither potentiates nor inhibits tissue plasminogen activator-induced thrombolysis.

Stewart D, Marder VJ, Starkman S, Saver JL.

J Thromb Haemost. 2006 Jul;4(7):1575-9.PMID: 16839356 [PubMed - indexed for MEDLINE]Related articles

Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke.

Marder VJ, Chute DJ, Starkman S, Abolian AM, Kidwell C, Liebeskind D, Ovbiagele B, Vinuela F, Duckwiler G, Jahan R, Vespa PM, Selco S, Rajajee V, Kim D, Sanossian N, Saver JL.

Stroke. 2006 Aug;37(8):2086-93. Epub 2006 Jun 22.PMID: 16794209 [PubMed - indexed for MEDLINE]Related articlesFree article

Conference summary and recommendations for research.

Hasan AA, Marder VJ.

Thromb Res. 2005;117(1-2):229-30. Epub 2005 Oct 12. No abstract available. PMID: 16225912 [PubMed - indexed for MEDLINE]Related articles

Anti-platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin.

Warkentin TE, Cook RJ, Marder VJ, Sheppard JA, Moore JC, Eriksson BI, Greinacher A, Kelton JG.

Blood. 2005 Dec 1;106(12):3791-6. Epub 2005 Aug 18.PMID: 16109780 [PubMed - indexed for MEDLINE]Related articlesFree article

Opinions and research priorities.

Bussey HI, Tapson V, Cannon RO 3rd, Nolan PE Jr, Gage B, Penzak SR, Spinler SA, De Smet P, Wittkowsky A, Lee AP, Ernst E, Marder VJ.

Thromb Res. 2005;117(1-2):155-69; discussion 170-4. Epub 2005 Aug 15. No abstract available. PMID: 16099491 [PubMed - indexed for MEDLINE]Related articles

The interaction of dietary supplements with antithrombotic agents: scope of the problem.

Marder VJ.

Thromb Res. 2005;117(1-2):7-13; discussion 39-42. Epub 2005 Aug 1. Review. No abstract available. PMID: 16076481 [PubMed - indexed for MEDLINE]Related articles

Moderate dose oral anticoagulant therapy in patients with the antiphospholipid syndrome? No.

Rickles FR, Marder VJ.

J Thromb Haemost. 2005 May;3(5):842-3. No abstract available. PMID: 15869572 [PubMed - indexed for MEDLINE]Related articles

Quantitative assessment of thrombus burden predicts the outcome of treatment for venous thrombosis: a systematic review.

Hull RD, Marder VJ, Mah AF, Biel RK, Brant RF.

Am J Med. 2005 May;118(5):456-64. Review.PMID: 15866245 [PubMed - indexed for MEDLINE]Related articles

Foundation and sites of action of antithrombotic agents.

Marder VJ, Rosove MH, Minning DM.

Best Pract Res Clin Haematol. 2004 Mar;17(1):3-22. Review.PMID: 15171955 [PubMed - indexed for MEDLINE]Related articles

Locally delivered plasmin: why should it be superior to plasminogen activators for direct thrombolysis?

Novokhatny VV, Jesmok GJ, Landskroner KA, Marder VJ, Zimmerman TP.

Trends Pharmacol Sci. 2004 Feb;25(2):72-5. Review.PMID: 15102492 [PubMed - indexed for MEDLINE]Related articles

Relationship between intermittent claudication, inflammation, thrombosis, and recurrent cardiac events among survivors of myocardial infarction.

Narins CR, Zareba W, Moss AJ, Marder VJ, Ridker PM, Krone RJ, Lichstein E.

Arch Intern Med. 2004 Feb 23;164(4):440-6.PMID: 14980996 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety of plasmin in the setting of concomitant aspirin and heparin administration in an animal model of bleeding.

Sadeghi S, Marder VJ, Stewart D, Kong M, Humphries J, Baumbach GA, Jesmok G.

J Thromb Haemost. 2003 Dec;1(12):2621-5.PMID: 14675099 [PubMed - indexed for MEDLINE]Related articles

Metabolic syndrome best defines the multivariate distribution of blood variables in postinfarction patients.

Corsetti JP, Zareba W, Moss AJ, Ridker PM, Marder VJ, Rainwater DL, Sparks CE.

Atherosclerosis. 2003 Dec;171(2):351-8.PMID: 14644407 [PubMed - indexed for MEDLINE]Related articles

Oral heparin administration with a novel drug delivery agent (SNAC) in healthy volunteers and patients undergoing elective total hip arthroplasty.

Berkowitz SD, Marder VJ, Kosutic G, Baughman RA.

J Thromb Haemost. 2003 Sep;1(9):1914-9.PMID: 12941031 [PubMed - indexed for MEDLINE]Related articles

Life-threatening thrombotic thrombocytopenic purpura (TTP) in a patient with sickle cell-hemoglobin C disease.

Lee HE, Marder VJ, Logan LJ, Friedman S, Miller BJ.

Ann Hematol. 2003 Nov;82(11):702-4. Epub 2003 Aug 16.PMID: 12923661 [PubMed - indexed for MEDLINE]Related articles

Assessment of recombinant factor VIIa as an antidote for bleeding induced in the rabbit by low molecular weight heparin.

Chan S, Kong M, Minning DM, Hedner U, Marder VJ.

J Thromb Haemost. 2003 Apr;1(4):760-5.PMID: 12871413 [PubMed - indexed for MEDLINE]Related articles

Association between inflammatory markers, hemostatic, and lipid factors in postinfarction patients.

Harb TS, Zareba W, Moss AJ, Ridker PM, Rifai N, Marder VJ, Miller-Watelet L; THROMBO Investigators.

Am J Cardiol. 2003 May 1;91(9):1120-3. No abstract available. PMID: 12714160 [PubMed - indexed for MEDLINE]Related articles

History of hypertension and enhanced thrombogenic activity in postinfarction patients.

Fadl YY, Zareba W, Moss AJ, Marder VJ, Sparks CS, Miller Watelet LF, Carroll ER.

Hypertension. 2003 Apr;41(4):943-9. Epub 2003 Mar 10.PMID: 12629034 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct dose-dependent effects of plasmin and TPA on coagulation and hemorrhage.

Stewart D, Kong M, Novokhatny V, Jesmok G, Marder VJ.

Blood. 2003 Apr 15;101(8):3002-7. Epub 2002 Nov 21.PMID: 12446443 [PubMed - indexed for MEDLINE]Related articlesFree article

Towards safer thrombolytic therapy.

Marder VJ, Stewart D.

Semin Hematol. 2002 Jul;39(3):206-16. Review.PMID: 12124683 [PubMed - indexed for MEDLINE]Related articles

Maximized hemostasis.

Marder VJ.

Thromb Haemost. 2002 Apr;87(4):555-6. No abstract available. PMID: 12008934 [PubMed - indexed for MEDLINE]Related articles

Use of thrombolytic therapy for acute myocardial infarction: effects of gender and age on treatment rates.

Kaplan KL, Fitzpatrick P, Cox C, Shammas NW, Marder VJ.

J Thromb Thrombolysis. 2002 Feb;13(1):21-6.PMID: 11994556 [PubMed - indexed for MEDLINE]Related articles

Association of C-reactive protein and serum amyloid A with recurrent coronary events in stable patients after healing of acute myocardial infarction.

Harb TS, Zareba W, Moss AJ, Ridker PM, Marder VJ, Rifai N, Miller Watelet LF, Arora R, Brown MW, Case RB, Dwyer EM Jr, Gillespie JA, Goldstein RE, Greenberg H, Hochman J, Krone RJ, Liang CS, Lichstein E, Little W, Marcus FI, Oakes D, Sparks CE, VanVoorhees L; THROMBO Investigators.

Am J Cardiol. 2002 Jan 15;89(2):216-21. No abstract available. PMID: 11792346 [PubMed - indexed for MEDLINE]Related articles

Thrombolytic therapy: 2001.

Marder VJ.

Blood Rev. 2001 Sep;15(3):143-57. Review. No abstract available. PMID: 11735162 [PubMed - indexed for MEDLINE]Related articles

Orally active heparin and low-molecular-weight heparin.

Pineo GF, Hull RD, Marder VJ.

Curr Opin Pulm Med. 2001 Sep;7(5):344-8. Review.PMID: 11584187 [PubMed - indexed for MEDLINE]Related articles

Increased level of von Willebrand factor is significantly and independently associated with diabetes in postinfarction patients. THROMBO Investigators.

Zareba W, Pancio G, Moss AJ, Kalaria VG, Marder VJ, Weiss HJ, Watelet LF, Sparks CE.

Thromb Haemost. 2001 Sep;86(3):791-9.PMID: 11583309 [PubMed - indexed for MEDLINE]Related articles

Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit.

Marder VJ, Landskroner K, Novokhatny V, Zimmerman TP, Kong M, Kanouse JJ, Jesmok G.

Thromb Haemost. 2001 Sep;86(3):739-45.PMID: 11583303 [PubMed - indexed for MEDLINE]Related articles

Timing of initial administration of low-molecular-weight heparin prophylaxis against deep vein thrombosis in patients following elective hip arthroplasty: a systematic review.

Hull RD, Pineo GF, Stein PD, Mah AF, MacIsaac SM, Dahl OE, Ghali WA, Butcher MS, Brant RF, Bergqvist D, Hamulyák K, Francis CW, Marder VJ, Raskob GE.

Arch Intern Med. 2001 Sep 10;161(16):1952-60. Review.PMID: 11525697 [PubMed - indexed for MEDLINE]Related articlesFree article

Acquired thrombophilic syndromes.

Matei D, Brenner B, Marder VJ.

Blood Rev. 2001 Mar;15(1):31-48. Review.PMID: 11333137 [PubMed - indexed for MEDLINE]Related articles

Effect of smoking on lipid and thrombogenic factors two months after acute myocardial infarction.

Fisher SD, Zareba W, Moss AJ, Marder VJ, Sparks CE, Hochman J, Liang C, Krone RJ; THROMBO Investigators.

Am J Cardiol. 2000 Oct 15;86(8):813-8.PMID: 11024393 [PubMed - indexed for MEDLINE]Related articles

Cocaine and Buerger disease: is there a pathogenetic association?

Marder VJ, Mellinghoff IK.

Arch Intern Med. 2000 Jul 10;160(13):2057-60.PMID: 10888980 [PubMed - indexed for MEDLINE]Related articles

Gender-related differences in thrombogenic factors predicting recurrent cardiac events in patients after acute myocardial infarction. The THROMBO Investigators.

Kalaria VG, Zareba W, Moss AJ, Pancio G, Marder VJ, Morrissey JH, Weiss HJ, Sparks CE, Greenberg H, Dwyer E, Goldstein R, Watelet LF.

Am J Cardiol. 2000 Jun 15;85(12):1401-8.PMID: 10856383 [PubMed - indexed for MEDLINE]Related articles

Cloning of guinea pig tissue factor cDNA: comparison of primary structure among six mammalian species.

Shi RJ, Li WZ, Marder VJ, Sporn LA.

Thromb Haemost. 2000 Mar;83(3):455-61.PMID: 10744153 [PubMed - indexed for MEDLINE]Related articles

Post-transcriptional regulation of endothelial cell plasminogen activator inhibitor-1 expression during R. rickettsii infection.

Shi RJ, Simpson-Haidaris PJ, Marder VJ, Silverman DJ, Sporn LA.

Microb Pathog. 2000 Mar;28(3):127-33.PMID: 10702354 [PubMed - indexed for MEDLINE]Related articles

Reactivity of soluble fibrin assays with plasmic degradation products of fibrin and in patients receiving fibrinolytic therapy.

McCarron BI, Marder VJ, Francis CW.

Thromb Haemost. 1999 Dec;82(6):1722-9.PMID: 10613661 [PubMed - indexed for MEDLINE]Related articles

Phospholipid-bound tissue factor modulates both thrombin generation and APC-mediated factor Va inactivation.

Váradi K, Siekmann J, Turecek PL, Schwarz HP, Marder VJ.

Thromb Haemost. 1999 Dec;82(6):1673-9.PMID: 10613654 [PubMed - indexed for MEDLINE]Related articles

Automated latex agglutination and ELISA testing yield equivalent D-dimer results in patients with recent myocardial infarction. THROMBO Research Investigators.

Marder VJ, Zareba W, Horan JT, Moss AJ, Kanouse JJ.

Thromb Haemost. 1999 Nov;82(5):1412-6.PMID: 10595629 [PubMed - indexed for MEDLINE]Related articles

Hematologic neoplasia and the central nervous system.

Sham RL, Phatak PD, Kouides PA, Janas JA, Marder VJ.

Am J Hematol. 1999 Dec;62(4):234-8.PMID: 10589079 [PubMed - indexed for MEDLINE]Related articles

A soluble fibrin standard: comparable dose-response with immunologic and functional assays.

McCarron BI, Marder VJ, Kanouse JJ, Francis CW.

Thromb Haemost. 1999 Jul;82(1):145-8.PMID: 10456469 [PubMed - indexed for MEDLINE]Related articles

Thrombogenic factors and recurrent coronary events.

Moss AJ, Goldstein RE, Marder VJ, Sparks CE, Oakes D, Greenberg H, Weiss HJ, Zareba W, Brown MW, Liang CS, Lichstein E, Little WC, Gillespie JA, Van Voorhees L, Krone RJ, Bodenheimer MM, Hochman J, Dwyer EM Jr, Arora R, Marcus FI, Watelet LF, Case RB.

Circulation. 1999 May 18;99(19):2517-22.PMID: 10330382 [PubMed - indexed for MEDLINE]Related articlesFree article

Infections affecting blood cell morphology.

Phatak PD, Janas JS, Kouides P, Leisveld J, Shafer J, Marder VJ.

Am J Hematol. 1998 Nov;59(3):238-41. No abstract available. PMID: 9798663 [PubMed - indexed for MEDLINE]Related articles

NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection.

Clifton DR, Goss RA, Sahni SK, van Antwerp D, Baggs RB, Marder VJ, Silverman DJ, Sporn LA.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4646-51.PMID: 9539792 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteasome-independent activation of nuclear factor kappaB in cytoplasmic extracts from human endothelial cells by Rickettsia rickettsii.

Sahni SK, Van Antwerp DJ, Eremeeva ME, Silverman DJ, Marder VJ, Sporn LA.

Infect Immun. 1998 May;66(5):1827-33.PMID: 9573057 [PubMed - indexed for MEDLINE]Related articlesFree article