PubMed

Efficacy and safety of peginterferon alfa-2a (40KD) plus ribavirin in hepatitis C patients with advanced fibrosis and cirrhosis.

Bruno S, Shiffman ML, Roberts SK, Gane EJ, Messinger D, Hadziyannis SJ, Marcellin P.

Hepatology. 2009 Sep 29. [Epub ahead of print]PMID: 19918980 [PubMed - as supplied by publisher]Related articles

Safety and efficacy of viramidine versus ribavirin in ViSER2: Randomized, double-blind study in therapy-naive hepatitis C patients.

Marcellin P, Gish RG, Gitlin N, Heise J, Halliman DG, Chun E, Rodriguez-Torres M.

J Hepatol. 2009 Oct 23. [Epub ahead of print]PMID: 19913323 [PubMed - as supplied by publisher]Related articles

Clinical performances of two real-time PCR assays and bDNA/TMA to early monitor treatment outcome in patients with chronic hepatitis C.

Martinot-Peignoux M, Khiri H, Leclere L, Maylin S, Marcellin P, Halfon P.

J Clin Virol. 2009 Nov;46(3):216-21. Epub 2009 Sep 12.PMID: 19748822 [PubMed - in process]Related articles

Hepatitis C: The role of new interferons in the era of STAT-C.

Moucari R, Marcellin P.

Nat Rev Gastroenterol Hepatol. 2009 Sep;6(9):509-11.PMID: 19713984 [PubMed - indexed for MEDLINE]Related articles

Response to antiviral treatment in patients infected with hepatitis B virus genotypes E-H.

Erhardt A, Göbel T, Ludwig A, Lau GK, Marcellin P, van Bömmel F, Heinzel-Pleines U, Adams O, Häussinger D.

J Med Virol. 2009 Oct;81(10):1716-20.PMID: 19697400 [PubMed - indexed for MEDLINE]Related articles

Chronic hepatitis B: back to the future with HBsAg.

Moucari R, Lada O, Marcellin P.

Expert Rev Anti Infect Ther. 2009 Aug;7(6):633-6. No abstract available. PMID: 19681689 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and geographical origin: major predictors of liver fibrosis and response to peginterferon and ribavirin in HCV-4.

Moucari R, Ripault MP, Martinot-Peignoux M, Voitot H, Cardoso AC, Stern C, Boyer N, Maylin S, Nicolas-Chanoine MH, Vidaud M, Valla D, Bedossa P, Marcellin P.

Gut. 2009 Dec;58(12):1662-9. Epub 2009 Aug 10.PMID: 19671541 [PubMed - in process]Related articles

Virological response at 4 weeks to predict outcome of hepatitis C treatment with pegylated interferon and ribavirin.

Martinot-Peignoux M, Maylin S, Moucari R, Ripault MP, Boyer N, Cardoso AC, Giuily N, Castelnau C, Pouteau M, Stern C, Aupérin A, Bedossa P, Asselah T, Marcellin P.

Antivir Ther. 2009;14(4):501-11.PMID: 19578235 [PubMed - indexed for MEDLINE]Related articles

[Hepatitis C: the recovery]

Marcellin P.

Gastroenterol Clin Biol. 2009 Aug-Sep;33(8-9):819-29. Epub 2009 Jun 21. French. PMID: 19541439 [PubMed - in process]Related articles

Emergency transplantation for acute reactivation of chronic hepatitis B with high viral load: role of antiviral therapy.

Moucari R, Francoz C, Lada O, Abdel Razek W, Marcellin P, Valla D, Belghiti J, Durand F.

Liver Int. 2009 May;29(5):775-6. No abstract available. PMID: 19422074 [PubMed - indexed for MEDLINE]Related articles

Re-treatment of patients with chronic hepatitis C who do not respond to peginterferon-alpha2b: a randomized trial.

Jensen DM, Marcellin P, Freilich B, Andreone P, Di Bisceglie A, Brandão-Mello CE, Reddy KR, Craxi A, Martin AO, Teuber G, Messinger D, Thommes JA, Tietz A.

Ann Intern Med. 2009 Apr 21;150(8):528-40.PMID: 19380853 [PubMed - indexed for MEDLINE]Related articlesFree article

High rates of HBsAg seroconversion in HBeAg-positive chronic hepatitis B patients responding to interferon: a long-term follow-up study.

Moucari R, Korevaar A, Lada O, Martinot-Peignoux M, Boyer N, Mackiewicz V, Dauvergne A, Cardoso AC, Asselah T, Nicolas-Chanoine MH, Vidaud M, Valla D, Bedossa P, Marcellin P.

J Hepatol. 2009 Jun;50(6):1084-92. Epub 2009 Mar 9.PMID: 19376603 [PubMed - indexed for MEDLINE]Related articles

Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B.

Brunetto MR, Moriconi F, Bonino F, Lau GK, Farci P, Yurdaydin C, Piratvisuth T, Luo K, Wang Y, Hadziyannis S, Wolf E, McCloud P, Batrla R, Marcellin P.

Hepatology. 2009 Apr;49(4):1141-50.PMID: 19338056 [PubMed - indexed for MEDLINE]Related articles

Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a.

Marcellin P, Bonino F, Lau GK, Farci P, Yurdaydin C, Piratvisuth T, Jin R, Gurel S, Lu ZM, Wu J, Popescu M, Hadziyannis S; Peginterferon alfa-2a in HBeAg-negative Chronic Hepatitis B Study Group.

Gastroenterology. 2009 Jun;136(7):2169-2179.e1-4. Epub 2009 Mar 19.PMID: 19303414 [PubMed - indexed for MEDLINE]Related articles

Protease and polymerase inhibitors for the treatment of hepatitis C.

Asselah T, Benhamou Y, Marcellin P.

Liver Int. 2009 Jan;29 Suppl 1:57-67. Review.PMID: 19207967 [PubMed - indexed for MEDLINE]Related articles

Hepatitis B and hepatitis C in 2009.

Marcellin P.

Liver Int. 2009 Jan;29 Suppl 1:1-8. Review.PMID: 19207959 [PubMed - indexed for MEDLINE]Related articles

Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus.

Poynard T, Ngo Y, Marcellin P, Hadziyannis S, Ratziu V, Benhamou Y; Adefovir Dipivoxil 437 and 438 Study Groups.

J Viral Hepat. 2009 Mar;16(3):203-13. Epub 2008 Oct 22.PMID: 19175871 [PubMed - indexed for MEDLINE]Related articles

Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients.

Moucari R, Mackiewicz V, Lada O, Ripault MP, Castelnau C, Martinot-Peignoux M, Dauvergne A, Asselah T, Boyer N, Bedossa P, Valla D, Vidaud M, Nicolas-Chanoine MH, Marcellin P.

Hepatology. 2009 Apr;49(4):1151-7.PMID: 19115222 [PubMed - indexed for MEDLINE]Related articles

What is the safe duration of therapy for patients infected with HCV genotype 6?

Antaki N, Marcellin P.

Nat Clin Pract Gastroenterol Hepatol. 2009 Feb;6(2):78-9. Epub 2008 Dec 17.PMID: 19092790 [PubMed - indexed for MEDLINE]Related articles

Sustained virological response is associated with clearance of hepatitis C virus RNA and a decrease in hepatitis C virus antibody.

Maylin S, Martinot-Peignoux M, Ripault MP, Moucari R, Cardoso AC, Boyer N, Giuily N, Castelnau C, Pouteau M, Asselah T, Nicolas-Chanoine MH, Marcellin P.

Liver Int. 2009 Apr;29(4):511-7. Epub 2008 Dec 9.PMID: 19076273 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression and hepatitis C virus infection.

Asselah T, Bièche I, Sabbagh A, Bedossa P, Moreau R, Valla D, Vidaud M, Marcellin P.

Gut. 2009 Jun;58(6):846-58. Epub 2008 Dec 11. Review.PMID: 19074178 [PubMed - indexed for MEDLINE]Related articlesFree article

Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B.

Marcellin P, Heathcote EJ, Buti M, Gane E, de Man RA, Krastev Z, Germanidis G, Lee SS, Flisiak R, Kaita K, Manns M, Kotzev I, Tchernev K, Buggisch P, Weilert F, Kurdas OO, Shiffman ML, Trinh H, Washington MK, Sorbel J, Anderson J, Snow-Lampart A, Mondou E, Quinn J, Rousseau F.

N Engl J Med. 2008 Dec 4;359(23):2442-55.PMID: 19052126 [PubMed - indexed for MEDLINE]Related articlesFree article

Clevudine: a promising therapy for the treatment of chronic hepatitis B.

Asselah T, Lada O, Moucari R, Marcellin P.

Expert Opin Investig Drugs. 2008 Dec;17(12):1963-74. Review.PMID: 19012511 [PubMed - indexed for MEDLINE]Related articles

Patient education improves adherence to peg-interferon and ribavirin in chronic genotype 2 or 3 hepatitis C virus infection: a prospective, real-life, observational study.

Cacoub P, Ouzan D, Melin P, Lang JP, Rotily M, Fontanges T, Varastet M, Chousterman M, Marcellin P.

World J Gastroenterol. 2008 Oct 28;14(40):6195-203.PMID: 18985810 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of liver fibrosis using transient elastography in patients with alcoholic liver disease.

Nahon P, Kettaneh A, Tengher-Barna I, Ziol M, de Lédinghen V, Douvin C, Marcellin P, Ganne-Carrié N, Trinchet JC, Beaugrand M.

J Hepatol. 2008 Dec;49(6):1062-8. Epub 2008 Oct 7.PMID: 18930329 [PubMed - indexed for MEDLINE]Related articles

Sustained hepatitis B e antigen seroconversion in patients with chronic hepatitis B after adefovir dipivoxil treatment: analysis of precore and basal core promoter mutants.

Wu IC, Shiffman ML, Tong MJ, Marcellin P, Mondou E, Frederick D, Snow-Lampart A, Sorbel J, Rousseau F, Chang TT.

Clin Infect Dis. 2008 Nov 15;47(10):1305-11.PMID: 18840078 [PubMed - indexed for MEDLINE]Related articles

Dynamic evolution of therapy for chronic hepatitis C: how will novel agents be incorporated into the standard of care?

Zeuzem S, Nelson DR, Marcellin P.

Antivir Ther. 2008;13(6):747-60. Review.PMID: 18839776 [PubMed - indexed for MEDLINE]Related articles

Adefovir dipivoxil is effective for the treatment of cirrhotic patients with lamivudine failure.

Zoulim F, Parvaz P, Marcellin P, Zarski JP, Beaugrand M, Benhamou Y, Bailly F, Maynard M, Trepo C, Trylesinski A, Monchecourt F; VIRESPA study group.

Liver Int. 2009 Mar;29(3):420-6. Epub 2008 Sep 15.PMID: 18795900 [PubMed - indexed for MEDLINE]Related articles

[Treatment of chronic hepatitis B]

Asselah T, Lada O, Boyer N, Martinot M, Marcellin P.

Gastroenterol Clin Biol. 2008 Aug-Sep;32(8-9):749-68. Epub 2008 Sep 4. Review. French. PMID: 18775613 [PubMed - indexed for MEDLINE]Related articles

Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B.

Marcellin P, Chang TT, Lim SG, Sievert W, Tong M, Arterburn S, Borroto-Esoda K, Frederick D, Rousseau F.

Hepatology. 2008 Sep;48(3):750-8.PMID: 18752330 [PubMed - indexed for MEDLINE]Related articles

Significant gene expression differences in histologically "Normal" liver biopsies: Implications for control tissue.

Asselah T, Bièche I, Laurendeau I, Martinot-Peignoux M, Paradis V, Vidaud D, Valla DC, Bedossa P, Marcellin P, Vidaud M.

Hepatology. 2008 Sep;48(3):953-62.PMID: 18726958 [PubMed - indexed for MEDLINE]Related articles

[Management of chronic hepatitis in 2008]

Pol S, Marcellin P.

Gastroenterol Clin Biol. 2008 Mar;32(3 Pt 2):S71-3. French. No abstract available. PMID: 18675183 [PubMed - indexed for MEDLINE]Related articles

[Management of chronic hepatitis C in 2008]

Pol S, Marcellin P.

Gastroenterol Clin Biol. 2008 Mar;32(3 Pt 2):S121-4. Review. French. No abstract available. PMID: 18675182 [PubMed - indexed for MEDLINE]Related articles

[Hepatitis C, cirrhosis and hepatocellular carcinoma]

Zarski JP, Doffoel M, Filoche B, Marcellin P, Samuel D, Bedossa P.

Gastroenterol Clin Biol. 2008 Mar;32(3 Pt 2):S117-20. Review. French. PMID: 18675181 [PubMed - indexed for MEDLINE]Related articles

[Treatment "à la carte" of chronic hepatitis B]

Marcellin P, Asselah T, Lada O.

Gastroenterol Clin Biol. 2008 Jan;32(1 Pt 2):S1-5. French. No abstract available. PMID: 18662604 [PubMed - indexed for MEDLINE]Related articles

Non-invasive assessment of liver fibrosis by stiffness measurement in patients with chronic hepatitis B.

Marcellin P, Ziol M, Bedossa P, Douvin C, Poupon R, de Lédinghen V, Beaugrand M.

Liver Int. 2009 Feb;29(2):242-7. Epub 2008 Jul 9.PMID: 18637064 [PubMed - indexed for MEDLINE]Related articles

Eradication of hepatitis C virus in patients successfully treated for chronic hepatitis C.

Maylin S, Martinot-Peignoux M, Moucari R, Boyer N, Ripault MP, Cazals-Hatem D, Giuily N, Castelnau C, Cardoso AC, Asselah T, Féray C, Nicolas-Chanoine MH, Bedossa P, Marcellin P.

Gastroenterology. 2008 Sep;135(3):821-9. Epub 2008 May 21.PMID: 18593587 [PubMed - indexed for MEDLINE]Related articles

Allogeneic hematopoietic cell transplant in HCV-infected patients.

Peffault de Latour R, Ribaud P, Robin M, Valla D, Marcellin P, Socié G, Asselah T.

J Hepatol. 2008 Jun;48(6):1008-17. Epub 2008 Apr 1. Review.PMID: 18433917 [PubMed - indexed for MEDLINE]Related articles

Response-guided therapy: optimizing treatment now and in the future.

Marcellin P, Rizzetto M.

Antivir Ther. 2008;13 Suppl 1:1-2. No abstract available. PMID: 18432156 [PubMed - indexed for MEDLINE]Related articles

Clinical trial: a phase II, randomized study evaluating the safety, pharmacokinetics and anti-viral activity of clevudine for 12 weeks in patients with chronic hepatitis B.

Lim SG, Leung N, Hann HW, Lau GK, Trepo C, Mommeja-Marin H, Moxham C, Sorbel J, Snow A, Blum MR, Rousseau F, Marcellin P.

Aliment Pharmacol Ther. 2008 Jun;27(12):1282-92. Epub 2008 Mar 22.PMID: 18363895 [PubMed - indexed for MEDLINE]Related articles

Comparing the safety, tolerability and quality of life in patients with chronic hepatitis B vs chronic hepatitis C treated with peginterferon alpha-2a.

Marcellin P, Lau GK, Zeuzem S, Heathcote EJ, Pockros PJ, Reddy KR, Piratvisuth T, Farci P, Chow WC, Jia JD, Paik W, Wintfeld N, Pluck N.

Liver Int. 2008 Apr;28(4):477-85.PMID: 18339074 [PubMed - indexed for MEDLINE]Related articles

Relapse of hepatitis C virus-associated mixed cryoglobulinemia vasculitis in patients with sustained viral response.

Landau DA, Saadoun D, Halfon P, Martinot-Peignoux M, Marcellin P, Fois E, Cacoub P.

Arthritis Rheum. 2008 Feb;58(2):604-11.PMID: 18240235 [PubMed - indexed for MEDLINE]Related articlesFree article

HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B.

Fried MW, Piratvisuth T, Lau GK, Marcellin P, Chow WC, Cooksley G, Luo KX, Paik SW, Liaw YF, Button P, Popescu M.

Hepatology. 2008 Feb;47(2):428-34.PMID: 18220290 [PubMed - indexed for MEDLINE]Related articles

Hepatic steatosis in chronic hepatitis C: baseline host and viral characteristics and influence on response to therapy with peginterferon alpha-2a plus ribavirin.

Reddy KR, Govindarajan S, Marcellin P, Bernstein D, Dienstag JL, Bodenheimer H Jr, Rakela J, Messinger D, Schmidt G, Ackrill A, Hadziyannis SJ.

J Viral Hepat. 2008 Feb;15(2):129-36.PMID: 18184196 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis.

Moucari R, Asselah T, Cazals-Hatem D, Voitot H, Boyer N, Ripault MP, Sobesky R, Martinot-Peignoux M, Maylin S, Nicolas-Chanoine MH, Paradis V, Vidaud M, Valla D, Bedossa P, Marcellin P.

Gastroenterology. 2008 Feb;134(2):416-23. Epub 2007 Nov 12.PMID: 18164296 [PubMed - indexed for MEDLINE]Related articles

Mortality related to chronic hepatitis B and chronic hepatitis C in France: evidence for the role of HIV coinfection and alcohol consumption.

Marcellin P, Pequignot F, Delarocque-Astagneau E, Zarski JP, Ganne N, Hillon P, Antona D, Bovet M, Mechain M, Asselah T, Desenclos JC, Jougla E.

J Hepatol. 2008 Feb;48(2):200-7. Epub 2007 Nov 20.PMID: 18086507 [PubMed - indexed for MEDLINE]Related articles

Clinical trial: interferon alpha-2b continuous long-term therapy vs. repeated 24-week cycles for re-treating chronic hepatitis C.

McHutchison JG, Patel K, Schiff ER, Gitlin N, Mur RE, Everson GT, Carithers RL Jr, Davis GL, Marcellin P, Shiffman ML, Harvey J, Albrecht JK; International Hepatitis Interventional Therapy Group.

Aliment Pharmacol Ther. 2008 Mar 1;27(5):422-32. Epub 2007 Dec 11.PMID: 18081733 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute hepatitis E with severe jaundice: report of three cases.

Moucari R, Bernuau J, Nicand E, Cazals-hatem D, Valla D, Marcellin P, Asselah T.

Eur J Gastroenterol Hepatol. 2007 Nov;19(11):1012-5.PMID: 18049173 [PubMed - indexed for MEDLINE]Related articles

Clinical trial: effects of adefovir dipivoxil therapy in Asian and Caucasian patients with chronic hepatitis B.

Lim SG, Marcellin P, Tassopoulos N, Hadziyannis S, Chang TT, Tong M, Sievert W, Hu P, Arterburn S, Brosgart CL; International Investigator Groups for Studies 437 and 438.

Aliment Pharmacol Ther. 2007 Nov 15;26(10):1419-28.PMID: 17983369 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon therapy for chronic hepatitis B.

Asselah T, Lada O, Moucari R, Martinot M, Boyer N, Marcellin P.

Clin Liver Dis. 2007 Nov;11(4):839-49, viii. Review.PMID: 17981231 [PubMed - indexed for MEDLINE]Related articles