PubMed

The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone.

Glier MB, Pissios P, Babich SL, Macdonald ML, Hayden MR, Maratos-Flier E, Gibson WT.

Peptides. 2009 Oct 31. [Epub ahead of print]PMID: 19883709 [PubMed - as supplied by publisher]Related articles

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis.

Badman MK, Koester A, Flier JS, Kharitonenkov A, Maratos-Flier E.

Endocrinology. 2009 Nov;150(11):4931-40. Epub 2009 Oct 9.PMID: 19819944 [PubMed - indexed for MEDLINE]Related articles

A Very Low Carbohydrate Ketogenic Diet Improves Glucose Tolerance in ob/ob Mice Independent of Weight Loss.

Badman MK, Kennedy AR, Adams AC, Pissios P, Maratos-Flier E.

Am J Physiol Endocrinol Metab. 2009 Sep 8. [Epub ahead of print]PMID: 19738035 [PubMed - as supplied by publisher]Related articles

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism.

Patti ME, Houten SM, Bianco AC, Bernier R, Larsen PR, Holst JJ, Badman MK, Maratos-Flier E, Mun EC, Pihlajamaki J, Auwerx J, Goldfine AB.

Obesity (Silver Spring). 2009 Sep;17(9):1671-7. Epub 2009 Apr 9.PMID: 19360006 [PubMed - indexed for MEDLINE]Related articles

Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B.

Zhang R, Maratos-Flier E, Flier JS.

Endocrinology. 2009 Jul;150(7):3076-82. Epub 2009 Apr 9.PMID: 19359377 [PubMed - indexed for MEDLINE]Related articles

Abnormal response of melanin-concentrating hormone deficient mice to fasting: hyperactivity and rapid eye movement sleep suppression.

Willie JT, Sinton CM, Maratos-Flier E, Yanagisawa M.

Neuroscience. 2008 Oct 28;156(4):819-29. Epub 2008 Aug 31.PMID: 18809470 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight.

Zhang R, Dhillon H, Yin H, Yoshimura A, Lowell BB, Maratos-Flier E, Flier JS.

Endocrinology. 2008 Nov;149(11):5654-61. Epub 2008 Jul 31.PMID: 18669597 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanin-concentrating hormone as a mediator of intestinal inflammation.

Kokkotou E, Moss AC, Torres D, Karagiannides I, Cheifetz A, Liu S, O'Brien M, Maratos-Flier E, Pothoulakis C.

Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10613-8. Epub 2008 Jul 23.PMID: 18650383 [PubMed - indexed for MEDLINE]Related articlesFree article

Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice.

Bradley RL, Jeon JY, Liu FF, Maratos-Flier E.

Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E586-94. Epub 2008 Jun 24.PMID: 18577694 [PubMed - indexed for MEDLINE]Related articlesFree article

The long reach of leptin.

Maratos-Flier E.

Nat Med. 2008 Jun;14(6):604-6. No abstract available. PMID: 18535571 [PubMed - indexed for MEDLINE]Related articles

Dietary fatty acids differentially regulate production of TNF-alpha and IL-10 by murine 3T3-L1 adipocytes.

Bradley RL, Fisher FF, Maratos-Flier E.

Obesity (Silver Spring). 2008 May;16(5):938-44. Epub 2008 Feb 28.PMID: 18356844 [PubMed - indexed for MEDLINE]Related articles

Dysregulation of the mesolimbic dopamine system and reward in MCH-/- mice.

Pissios P, Frank L, Kennedy AR, Porter DR, Marino FE, Liu FF, Pothos EN, Maratos-Flier E.

Biol Psychiatry. 2008 Aug 1;64(3):184-91. Epub 2008 Feb 20.PMID: 18281019 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice.

Katic M, Kennedy AR, Leykin I, Norris A, McGettrick A, Gesta S, Russell SJ, Bluher M, Maratos-Flier E, Kahn CR.

Aging Cell. 2007 Dec;6(6):827-39.PMID: 18001293 [PubMed - indexed for MEDLINE]Related articles

More than satiety: central serotonin signaling and glucose homeostasis.

Pissios P, Maratos-Flier E.

Cell Metab. 2007 Nov;6(5):345-7.PMID: 17983579 [PubMed - indexed for MEDLINE]Related articles

What fuels fat.

Flier JS, Maratos-Flier E.

Sci Am. 2007 Sep;297(3):72-81. No abstract available. PMID: 17784627 [PubMed - indexed for MEDLINE]Related articles

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals.

Handschin C, Chin S, Li P, Liu F, Maratos-Flier E, Lebrasseur NK, Yan Z, Spiegelman BM.

J Biol Chem. 2007 Oct 12;282(41):30014-21. Epub 2007 Aug 16.PMID: 17702743 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states.

Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E.

Cell Metab. 2007 Jun;5(6):426-37.PMID: 17550778 [PubMed - indexed for MEDLINE]Related articles

A high-fat, ketogenic diet induces a unique metabolic state in mice.

Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1724-39. Epub 2007 Feb 13. Erratum in: Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1846. Roberson, Russell [added]. Am J Physiol Endocrinol Metab. 2009 May;296(5):E1179. PMID: 17299079 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanin concentrating hormone is a novel regulator of islet function and growth.

Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN.

Diabetes. 2007 Feb;56(2):311-9.PMID: 17259374 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin regulation of the mesoaccumbens dopamine pathway.

Fulton S, Pissios P, Manchon RP, Stiles L, Frank L, Pothos EN, Maratos-Flier E, Flier JS.

Neuron. 2006 Sep 21;51(6):811-22.PMID: 16982425 [PubMed - indexed for MEDLINE]Related articles

Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions.

Pissios P, Bradley RL, Maratos-Flier E.

Endocr Rev. 2006 Oct;27(6):606-20. Epub 2006 Jun 20. Review.PMID: 16788162 [PubMed - indexed for MEDLINE]Related articlesFree article

MCH-/- mice are resistant to aging-associated increases in body weight and insulin resistance.

Jeon JY, Bradley RL, Kokkotou EG, Marino FE, Wang X, Pissios P, Maratos-Flier E.

Diabetes. 2006 Feb;55(2):428-34.PMID: 16443777 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuropeptides, including neuropeptide Y and melanocortins, mediate lipolysis in murine adipocytes.

Bradley RL, Mansfield JP, Maratos-Flier E.

Obes Res. 2005 Apr;13(4):653-61.PMID: 15897473 [PubMed - indexed for MEDLINE]Related articles

The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance.

Georgescu D, Sears RM, Hommel JD, Barrot M, Bolaños CA, Marsh DJ, Bednarek MA, Bibb JA, Maratos-Flier E, Nestler EJ, DiLeone RJ.

J Neurosci. 2005 Mar 16;25(11):2933-40.PMID: 15772353 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms.

Kokkotou E, Jeon JY, Wang X, Marino FE, Carlson M, Trombly DJ, Maratos-Flier E.

Am J Physiol Regul Integr Comp Physiol. 2005 Jul;289(1):R117-24. Epub 2005 Feb 24.PMID: 15731402 [PubMed - indexed for MEDLINE]Related articles

LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin.

Bates SH, Dundon TA, Seifert M, Carlson M, Maratos-Flier E, Myers MG Jr.

Diabetes. 2004 Dec;53(12):3067-73.PMID: 15561935 [PubMed - indexed for MEDLINE]Related articlesFree article

Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice.

Blüher S, Moschos S, Bullen J Jr, Kokkotou E, Maratos-Flier E, Wiegand SJ, Sleeman MW, Mantzoros CS.

Diabetes. 2004 Nov;53(11):2787-96. Erratum in: Diabetes. 2005 Jan;54(1):296. Sleemann, Mark W [corrected to Sleeman, Mark W]. PMID: 15504958 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term resistance to diet-induced obesity in A/J mice is not associated with regulation of hypothalamic neuropeptides.

Bullen JW Jr, Ziotopoulou M, Ungsunan L, Misra J, Alevizos I, Kokkotou E, Maratos-Flier E, Stephanopoulos G, Mantzoros CS.

Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E662-70.PMID: 15361355 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.

Gibson WT, Pissios P, Trombly DJ, Luan J, Keogh J, Wareham NJ, Maratos-Flier E, O'Rahilly S, Farooqi IS.

Obes Res. 2004 May;12(5):743-9.PMID: 15166293 [PubMed - indexed for MEDLINE]Related articles

Estradiol-induced anorexia is independent of leptin and melanin-concentrating hormone.

Tritos NA, Segal-Lieberman G, Vezeridis PS, Maratos-Flier E.

Obes Res. 2004 Apr;12(4):716-24.PMID: 15090642 [PubMed - indexed for MEDLINE]Related articles

Responsiveness to peripherally administered melanocortins in lean and obese mice.

Blüher S, Ziotopoulou M, Bullen JW Jr, Moschos SJ, Ungsunan L, Kokkotou E, Maratos-Flier E, Mantzoros CS.

Diabetes. 2004 Jan;53(1):82-90.PMID: 14693701 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum ghrelin levels in response to glucose load in obese subjects post-gastric bypass surgery.

Tritos NA, Mun E, Bertkau A, Grayson R, Maratos-Flier E, Goldfine A.

Obes Res. 2003 Aug;11(8):919-24.PMID: 12917494 [PubMed - indexed for MEDLINE]Related articles

Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.

Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG Jr, Flier JS, Maratos-Flier E.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10085-90. Epub 2003 Aug 1.PMID: 12897241 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways.

Pissios P, Trombly DJ, Tzameli I, Maratos-Flier E.

Endocrinology. 2003 Aug;144(8):3514-23.PMID: 12865333 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanin-concentrating hormone: from fish skin to skinny mammals.

Pissios P, Maratos-Flier E.

Trends Endocrinol Metab. 2003 Jul;14(5):243-8. Review.PMID: 12826331 [PubMed - indexed for MEDLINE]Related articles

Cerebrospinal fluid ghrelin is negatively associated with body mass index.

Tritos NA, Kokkinos A, Lampadariou E, Alexiou E, Katsilambros N, Maratos-Flier E.

J Clin Endocrinol Metab. 2003 Jun;88(6):2943-6.PMID: 12788909 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT3 signalling is required for leptin regulation of energy balance but not reproduction.

Bates SH, Stearns WH, Dundon TA, Schubert M, Tso AW, Wang Y, Banks AS, Lavery HJ, Haq AK, Maratos-Flier E, Neel BG, Schwartz MW, Myers MG Jr.

Nature. 2003 Feb 20;421(6925):856-9.PMID: 12594516 [PubMed - indexed for MEDLINE]Related articles

NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting.

Segal-Lieberman G, Trombly DJ, Juthani V, Wang X, Maratos-Flier E.

Am J Physiol Endocrinol Metab. 2003 Jun;284(6):E1131-9. Epub 2003 Feb 11.PMID: 12582011 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain.

Tritos NA, Mastaitis JW, Kokkotou EG, Puigserver P, Spiegelman BM, Maratos-Flier E.

Brain Res. 2003 Jan 31;961(2):255-60.PMID: 12531492 [PubMed - indexed for MEDLINE]Related articles

Melanin-concentrating hormone activates signaling pathways in 3T3-L1 adipocytes.

Bradley RL, Mansfield JP, Maratos-Flier E, Cheatham B.

Am J Physiol Endocrinol Metab. 2002 Sep;283(3):E584-92.PMID: 12169453 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span.

Mobbs CV, Bray GA, Atkinson RL, Bartke A, Finch CE, Maratos-Flier E, Crawley JN, Nelson JF.

J Gerontol A Biol Sci Med Sci. 2001 Mar;56 Spec No 1:34-44. Review.PMID: 12088210 [PubMed - indexed for MEDLINE]Related articles

The stomach speaks--ghrelin and weight regulation.

Flier JS, Maratos-Flier E.

N Engl J Med. 2002 May 23;346(21):1662-3. No abstract available. PMID: 12024001 [PubMed - indexed for MEDLINE]Related articles

Characterization of melanin concentrating hormone and preproorexin expression in the murine hypothalamus.

Tritos NA, Mastaitis JW, Kokkotou E, Maratos-Flier E.

Brain Res. 2001 Mar 23;895(1-2):160-6.PMID: 11259773 [PubMed - indexed for MEDLINE]Related articles

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance.

Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E.

J Clin Invest. 2001 Feb;107(3):379-86.PMID: 11160162 [PubMed - indexed for MEDLINE]Related articlesFree article

Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain.

Kokkotou EG, Tritos NA, Mastaitis JW, Slieker L, Maratos-Flier E.

Endocrinology. 2001 Feb;142(2):680-6.PMID: 11159839 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of [Phe(13), Tyr(19)]-MCH analog binding activity to the MCH receptor.

Kokkotou E, Mastaitis JW, Qu D, Hoersch D, Slieker L, Bonter K, Tritos NA, Maratos-Flier E.

Neuropeptides. 2000 Jun-Aug;34(3-4):240-7.PMID: 11021987 [PubMed - indexed for MEDLINE]Related articles

Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes.

Bradley RL, Kokkotou EG, Maratos-Flier E, Cheatham B.

Diabetes. 2000 Jul;49(7):1073-7.PMID: 10909960 [PubMed - indexed for MEDLINE]Related articlesFree article

Energy homeostasis and body weight.

Flier J, Maratos-Flier E.

Curr Biol. 2000 Mar 23;10(6):R215-7. Review. No abstract available. PMID: 10744985 [PubMed - indexed for MEDLINE]Related articles

The branch point enzyme of the mevalonate pathway for protein prenylation is overexpressed in the ob/ob mouse and induced by adipogenesis.

Vicent D, Maratos-Flier E, Kahn CR.

Mol Cell Biol. 2000 Mar;20(6):2158-66.PMID: 10688662 [PubMed - indexed for MEDLINE]Related articlesFree article

Two important systems in energy homeostasis: melanocortins and melanin-concentrating hormone.

Tritos NA, Maratos-Flier E.

Neuropeptides. 1999 Oct;33(5):339-49. Review.PMID: 10657511 [PubMed - indexed for MEDLINE]Related articles