PubMed

Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice.

Senou M, Costa MJ, Massart C, Thimmesch M, Khalifa C, Poncin S, Boucquey M, Gérard AC, Audinot JN, Dessy C, Ruf J, Feron O, Devuyst O, Guiot Y, Dumont JE, Van Sande J, Many MC.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E438-51. Epub 2009 May 12.PMID: 19435853 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress in the thyroid gland: from harmlessness to hazard depending on the iodine content.

Poncin S, Gérard AC, Boucquey M, Senou M, Calderon PB, Knoops B, Lengelé B, Many MC, Colin IM.

Endocrinology. 2008 Jan;149(1):424-33. Epub 2007 Sep 20.PMID: 17884933 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of hydrogen peroxide in thyroid physiology and disease.

Song Y, Driessens N, Costa M, De Deken X, Detours V, Corvilain B, Maenhaut C, Miot F, Van Sande J, Many MC, Dumont JE.

J Clin Endocrinol Metab. 2007 Oct;92(10):3764-73. Epub 2007 Jul 31. Review.PMID: 17666482 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of adiponectin targeted to adipose tissue in transgenic mice: impaired adipocyte differentiation.

Bauche IB, El Mkadem SA, Pottier AM, Senou M, Many MC, Rezsohazy R, Penicaud L, Maeda N, Funahashi T, Brichard SM.

Endocrinology. 2007 Apr;148(4):1539-49. Epub 2007 Jan 4.PMID: 17204560 [PubMed - indexed for MEDLINE]Related articlesFree article

Reciprocal negative regulation between thyrotropin/3',5'-cyclic adenosine monophosphate-mediated proliferation and caveolin-1 expression in human and murine thyrocytes.

Costa MJ, Senou M, Van Rode F, Ruf J, Capello M, Dequanter D, Lothaire P, Dessy C, Dumont JE, Many MC, Van Sande J.

Mol Endocrinol. 2007 Apr;21(4):921-32. Epub 2007 Jan 3.PMID: 17202321 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteomic profiling of cold thyroid nodules.

Krause K, Karger S, Schierhorn A, Poncin S, Many MC, Fuhrer D.

Endocrinology. 2007 Apr;148(4):1754-63. Epub 2006 Dec 28.PMID: 17194741 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of adiponectin in skeletal muscle of type 2 diabetic mice: In vivo and in vitro studies.

Delaigle AM, Senou M, Guiot Y, Many MC, Brichard SM.

Diabetologia. 2006 Jun;49(6):1311-23. Epub 2006 Mar 29.PMID: 16570160 [PubMed - indexed for MEDLINE]Related articles

Quantification of cells expressing the thyrotropin receptor in extraocular muscles in thyroid associated orbitopathy.

Boschi A, Daumerie Ch, Spiritus M, Beguin C, Senou M, Yuksel D, Duplicy M, Costagliola S, Ludgate M, Many MC.

Br J Ophthalmol. 2005 Jun;89(6):724-9.PMID: 15923509 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxiredoxin 5 expression in the human thyroid gland.

Gérard AC, Many MC, Daumerie Ch, Knoops B, Colin IM.

Thyroid. 2005 Mar;15(3):205-9.PMID: 15785239 [PubMed - indexed for MEDLINE]Related articles

Sphingolipid-cholesterol domains (lipid rafts) in normal human and dog thyroid follicular cells are not involved in thyrotropin receptor signaling.

Costa MJ, Song Y, Macours P, Massart C, Many MC, Costagliola S, Dumont JE, Van Sande J, Vanvooren V.

Endocrinology. 2004 Mar;145(3):1464-72. Epub 2003 Dec 11.PMID: 14670987 [PubMed - indexed for MEDLINE]Related articlesFree article

Correlation between the loss of thyroglobulin iodination and the expression of thyroid-specific proteins involved in iodine metabolism in thyroid carcinomas.

Gérard AC, Daumerie C, Mestdagh C, Gohy S, De Burbure C, Costagliola S, Miot F, Nollevaux MC, Denef JF, Rahier J, Franc B, De Vijlder JJ, Colin IM, Many MC.

J Clin Endocrinol Metab. 2003 Oct;88(10):4977-83.PMID: 14557483 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa.

Contempré B, de Escobar GM, Denef JF, Dumont JE, Many MC.

Endocrinology. 2004 Feb;145(2):994-1002. Epub 2003 Sep 18.PMID: 14500569 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationships between cell division, expression of growth factors and microcirculation in the thyroids of Tg-A2aR transgenic mice and patients with Graves' disease.

Gérard AC, Denef JF, Many MC, Gathy P, de Burbure C, van den Hove MF, Coppée F, Ledent C, Colin IM.

J Endocrinol. 2003 May;177(2):269-77.PMID: 12740015 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural changes in the angiofollicular units between active and hypofunctioning follicles align with differences in the epithelial expression of newly discovered proteins involved in iodine transport and organification.

Gérard AC, Many MC, Daumerie C, Costagliola S, Miot F, DeVijlder JJ, Colin IM, Denef JF.

J Clin Endocrinol Metab. 2002 Mar;87(3):1291-9.PMID: 11889201 [PubMed - indexed for MEDLINE]Related articlesFree article

Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.

Costagliola S, Panneels V, Bonomi M, Koch J, Many MC, Smits G, Vassart G.

EMBO J. 2002 Feb 15;21(4):504-13.PMID: 11847099 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell necrosis and apoptosis are differentially regulated during goitre development and iodine-induced involution.

Mutaku JF, Poma JF, Many MC, Denef JF, van Den Hove MF.

J Endocrinol. 2002 Feb;172(2):375-86.PMID: 11834455 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for thyrotropin receptor immunoreactivity in pretibial connective tissue from patients with thyroid-associated dermopathy.

Daumerie C, Ludgate M, Costagliola S, Many MC.

Eur J Endocrinol. 2002 Jan;146(1):35-8.PMID: 11751064 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine model.

Arras M, Huaux F, Vink A, Delos M, Coutelier JP, Many MC, Barbarin V, Renauld JC, Lison D.

Am J Respir Cell Mol Biol. 2001 Apr;24(4):368-75.PMID: 11306428 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for co-ordinated changes between vascular endothelial growth factor and nitric oxide synthase III immunoreactivity, the functional status of the thyroid follicles, and the microvascular bed during chronic stimulation by low iodine and propylthiouracyl in old mice.

Gérard AC, Xhenseval V, Colin IM, Many MC, Denef JF.

Eur J Endocrinol. 2000 Jun;142(6):651-60.PMID: 10822230 [PubMed - indexed for MEDLINE]Related articlesFree article

Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

De Deken X, Wang D, Many MC, Costagliola S, Libert F, Vassart G, Dumont JE, Miot F.

J Biol Chem. 2000 Jul 28;275(30):23227-33.PMID: 10806195 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.

Costagliola S, Many MC, Denef JF, Pohlenz J, Refetoff S, Vassart G.

J Clin Invest. 2000 Mar;105(6):803-11.PMID: 10727449 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of an animal model of autoimmune thyroid eye disease.

Many MC, Costagliola S, Detrait M, Denef F, Vassart G, Ludgate MC.

J Immunol. 1999 Apr 15;162(8):4966-74.PMID: 10202044 [PubMed - indexed for MEDLINE]Related articlesFree article

Lung fibrosis induced by silica particles in NMRI mice is associated with an upregulation of the p40 subunit of interleukin-12 and Th-2 manifestations.

Huaux F, Lardot C, Arras M, Delos M, Many MC, Coutelier JP, Buchet JP, Renauld JC, Lison D.

Am J Respir Cell Mol Biol. 1999 Apr;20(4):561-72.PMID: 10100987 [PubMed - indexed for MEDLINE]Related articlesFree article

The thyrotropin receptor in thyroid eye disease.

Ludgate M, Crisp M, Lane C, Costagliola S, Vassart G, Weetman A, Daunerie C, Many MC.

Thyroid. 1998 May;8(5):411-3. Review.PMID: 9623732 [PubMed - indexed for MEDLINE]Related articles

Antigoitrogenic effect of combined supplementation with dl-alpha-tocopherol, ascorbic acid and beta-carotene and of dl-alpha-tocopherol alone in the rat.

Mutaku JF, Many MC, Colin I, Denef JF, van den Hove MF.

J Endocrinol. 1998 Mar;156(3):551-61.PMID: 9582512 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor.

Costagliola S, Rodien P, Many MC, Ludgate M, Vassart G.

J Immunol. 1998 Feb 1;160(3):1458-65.PMID: 9570567 [PubMed - indexed for MEDLINE]Related articlesFree article

Selenium deficiency and thyroid fibrosis. A key role for macrophages and transforming growth factor beta (TGF-beta).

Contempre B, Le Moine O, Dumont JE, Denef JF, Many MC.

Mol Cell Endocrinol. 1996 Nov 29;124(1-2):7-15.PMID: 9027319 [PubMed - indexed for MEDLINE]Related articles

Transfer of thyroiditis, with syngeneic spleen cells sensitized with the human thyrotropin receptor, to naive BALB/c and NOD mice.

Costagliola S, Many MC, Stalmans-Falys M, Vassart G, Ludgate M.

Endocrinology. 1996 Nov;137(11):4637-43.PMID: 8895327 [PubMed - indexed for MEDLINE]Related articles

Iodine-induced thyroid inhibition and cell necrosis: two consequences of the same free-radical mediated mechanism?

Denef JF, Many MC, van den Hove MF.

Mol Cell Endocrinol. 1996 Jul 23;121(1):101-3. Review. No abstract available. PMID: 8865171 [PubMed - indexed for MEDLINE]Related articles

What could mice tell us about goiter or other benign thyroid diseases?

Denef JF, Maniratunga S, Gérard AC, Many MC.

Exp Clin Endocrinol Diabetes. 1996;104 Suppl 3:48-51. Review.PMID: 8986424 [PubMed - indexed for MEDLINE]Related articles

The non-obese diabetic (NOD) mouse: an animal model for autoimmune thyroiditis.

Many MC, Maniratunga S, Denef JF.

Exp Clin Endocrinol Diabetes. 1996;104 Suppl 3:17-20. Review.PMID: 8986413 [PubMed - indexed for MEDLINE]Related articles

The autoimmune response induced by immunising female mice with recombinant human thyrotropin receptor varies with the genetic background.

Costagliola S, Many MC, Stalmans-Falys M, Vassart G, Ludgate M.

Mol Cell Endocrinol. 1995 Dec 29;115(2):199-206.PMID: 8824895 [PubMed - indexed for MEDLINE]Related articles

Two-step development of Hashimoto-like thyroiditis in genetically autoimmune prone non-obese diabetic mice: effects of iodine-induced cell necrosis.

Many MC, Maniratunga S, Varis I, Dardenne M, Drexhage HA, Denef JF.

J Endocrinol. 1995 Nov;147(2):311-20.PMID: 7490561 [PubMed - indexed for MEDLINE]Related articles

Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism.

Contempre B, Dumont JE, Denef JF, Many MC.

Eur J Endocrinol. 1995 Jul;133(1):99-109.PMID: 7627345 [PubMed - indexed for MEDLINE]Related articles

Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model.

Costagliola S, Many MC, Stalmans-Falys M, Tonacchera M, Vassart G, Ludgate M.

Endocrinology. 1994 Nov;135(5):2150-9.PMID: 7956939 [PubMed - indexed for MEDLINE]Related articles

Involvement of T cell immunity in the transient thyroid inflammation induced by iodide in goitrous BALB/C and nude mice.

Neu F, Rebai T, Denef JF, Many MC.

Autoimmunity. 1994;17(3):209-16.PMID: 7948605 [PubMed - indexed for MEDLINE]Related articles

High frequency of thymic ectopy in thyroids from autoimmune prone nonobese diabetic female mice.

Many MC, Drexhage HA, Denef JF.

Lab Invest. 1993 Sep;69(3):364-7.PMID: 8377477 [PubMed - indexed for MEDLINE]Related articles

Selenium deficiency aggravates the necrotizing effects of a high iodide dose in iodine deficient rats.

Contempre B, Denef JF, Dumont JE, Many MC.

Endocrinology. 1993 Apr;132(4):1866-8.PMID: 8462484 [PubMed - indexed for MEDLINE]Related articles

In vitro study of acute toxic effects of high iodide doses in human thyroid follicles.

Many MC, Mestdagh C, van den Hove MF, Denef JF.

Endocrinology. 1992 Aug;131(2):621-30.PMID: 1639011 [PubMed - indexed for MEDLINE]Related articles

Iodine and goiter involution.

Many MC, Denef JF.

Thyroidology. 1992 Apr;4(1):23-6. Review.PMID: 1284328 [PubMed - indexed for MEDLINE]Related articles

Correlated autoradiographic and ion-microscopic study of the role of iodine in the formation of "cold" follicles in young and old mice.

Mestdagh C, Many MC, Halpern S, Briançon C, Fragu P, Denef JF.

Cell Tissue Res. 1990 May;260(3):449-57.PMID: 2372804 [PubMed - indexed for MEDLINE]Related articles

Effects of iodide on class II-MHC antigen expression in iodine deficient hyperplastic thyroid glands.

Toussaint-Demylle D, Many MC, Theisen H, Kraal G, Denef JF.

Autoimmunity. 1990;7(1):51-62.PMID: 2103310 [PubMed - indexed for MEDLINE]Related articles

[Experimental goitrogenesis]

Denef JF, Ovaert C, Many MC.

Ann Endocrinol (Paris). 1989;50(1):1-15. Review. French. PMID: 2658730 [PubMed - indexed for MEDLINE]Related articles

Effects of iodide and thyroxine on iodine-deficient mouse thyroid: a morphological and functional study.

Many MC, Denef JF, Hamudi S, Cornette C, Haumont S, Beckers C.

J Endocrinol. 1986 Aug;110(2):203-10.PMID: 3746158 [PubMed - indexed for MEDLINE]Related articles

Direct toxic effect of iodide in excess on iodine-deficient thyroid glands: epithelial necrosis and inflammation associated with lipofuscin accumulation.

Mahmoud I, Colin I, Many MC, Denef JF.

Exp Mol Pathol. 1986 Jun;44(3):259-71.PMID: 3720915 [PubMed - indexed for MEDLINE]Related articles

Increased follicular heterogeneity in experimental colloid goiter produced by refeeding iodine excess after thyroid hyperplasia.

Many MC, Denef JF, Hamudi S, Haumont S.

Endocrinology. 1986 Feb;118(2):637-44.PMID: 3943488 [PubMed - indexed for MEDLINE]Related articles

Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution.

Many MC, Denef JF, Haumont S, van den Hove-Vandenbroucke MF, Cornette C, Beckers C.

Endocrinology. 1985 Feb;116(2):798-806.PMID: 3967628 [PubMed - indexed for MEDLINE]Related articles

Precocity of the endothelial proliferation during a course of rapid goitrogenesis.

Many MC, Denef JF, Haumont S.

Acta Endocrinol (Copenh). 1984 Apr;105(4):487-91.PMID: 6720234 [PubMed - indexed for MEDLINE]Related articles

Morphological and functional changes during thyroid hyperplasia and involution in C3H Mice: evidence for folliculoneogenesis during involution.

Many MC, Denef JF, Gathy P, Haumont S.

Endocrinology. 1983 Apr;112(4):1292-302.PMID: 6832046 [PubMed - indexed for MEDLINE]Related articles

Morphometry of nuclear pore complexes in thyroid cells during hyperplasia and involution.

Many MC, Denef JF, Cordier AC, Haumont S.

Mol Cell Endocrinol. 1981 Aug;23(2):137-49.PMID: 7274548 [PubMed - indexed for MEDLINE]Related articles