PubMed

In Vitro and In Vivo Isotope Effects with Hepatitis C Protease Inhibitors: Enhanced Plasma Exposure of Deuterated Telaprevir versus Telaprevir in Rats.

Maltais F, Jung YC, Chen M, Tanoury J, Perni RB, Mani N, Laitinen L, Huang H, Liao S, Gao H, Tsao H, Block E, Ma C, Shawgo RS, Town C, Brummel CL, Howe D, Pazhanisamy S, Raybuck S, Namchuk M, Bennani YL.

J Med Chem. 2009 Nov 6. [Epub ahead of print]PMID: 19894743 [PubMed - as supplied by publisher]Related articles

Performance during constant workrate cycling exercise in women with COPD and hyperinflation.

Laviolette L, O'Donnell DE, Webb KA, Hamilton AL, Kesten S, Maltais F.

COPD. 2009 Oct;6(5):340-51.PMID: 19863363 [PubMed - in process]Related articles

Paced-walk and step tests to assess exertional dyspnea in COPD.

Perrault H, Baril J, Henophy S, Rycroft A, Bourbeau J, Maltais F.

COPD. 2009 Oct;6(5):330-9.PMID: 19863362 [PubMed - in process]Related articles

Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control.

Aronov AM, Tang Q, Martinez-Botella G, Bemis GW, Cao J, Chen G, Ewing NP, Ford PJ, Germann UA, Green J, Hale MR, Jacobs M, Janetka JW, Maltais F, Markland W, Namchuk MN, Nanthakumar S, Poondru S, Straub J, ter Haar E, Xie X.

J Med Chem. 2009 Oct 22;52(20):6362-8.PMID: 19827834 [PubMed - in process]Related articles

Pulmonary rehabilitation in chronic obstructive pulmonary disease.

Saey D, Bernard S, Gagnon P, Laviolette L, Soicher J, Maltais F, Esgagne P, Coats V, Devost AA.

Panminerva Med. 2009 Jun;51(2):95-114.PMID: 19776711 [PubMed - in process]Related articles

Peripheral Muscle Dysfunction in Idiopathic Pulmonary Arterial Hypertension.

Mainguy V, Maltais F, Saey D, Gagnon P, Martel S, Simon M, Provencher S.

Thorax. 2009 Aug 30. [Epub ahead of print]PMID: 19720606 [PubMed - as supplied by publisher]Related articles

The Oort structural equation modeling approach detected a response shift after a COPD self-management program not detected by the Schmitt technique.

Ahmed S, Bourbeau J, Maltais F, Mansour A.

J Clin Epidemiol. 2009 Nov;62(11):1165-72. Epub 2009 Aug 6.PMID: 19664904 [PubMed - in process]Related articles

Pleural Effusions Following Cardiac Surgery. Prevalence, Risk Factors, and Clinical Features.

Labidi M, Baillot R, Dionne B, Lacasse Y, Maltais F, Boulet LP.

Chest. 2009 Jul 6. [Epub ahead of print]PMID: 19581352 [PubMed - as supplied by publisher]Related articles

Impact of preinduced quadriceps fatigue on exercise response in chronic obstructive pulmonary disease and healthy subjects.

Gagnon P, Saey D, Vivodtzev I, Laviolette L, Mainguy V, Milot J, Provencher S, Maltais F.

J Appl Physiol. 2009 Sep;107(3):832-40. Epub 2009 Jul 2.PMID: 19574500 [PubMed - indexed for MEDLINE]Related articles

Physiology of walking in patients with moderate to severe chronic obstructive pulmonary disease.

Marquis N, Debigaré R, Bouyer L, Saey D, Laviolette L, Brouillard C, Maltais F.

Med Sci Sports Exerc. 2009 Aug;41(8):1540-8.PMID: 19568207 [PubMed - indexed for MEDLINE]Related articles

Pulmonary rehabilitation: WHAT WE KNOW AND WHAT WE NEED TO KNOW.

Nici L, Raskin J, Rochester CL, Bourbeau JC, Carlin BW, Casaburi R, Celli BR, Cote C, Crouch RH, Diez-Morales LF, Donner CF, Fahy BF, Garvey C, Goldstein R, Lane-Reticker A, Lareau SC, Make B, Maltais F, McCormick J, Morgan MD, Ries A, Troosters T, ZuWallack R.

J Cardiopulm Rehabil Prev. 2009 May-Jun;29(3):141-51. Review.PMID: 19471135 [PubMed - indexed for MEDLINE]Related articles

Hypoxia alters contractile protein homeostasis in L6 myotubes.

Caron MA, Thériault ME, Paré ME, Maltais F, Debigaré R.

FEBS Lett. 2009 May 6;583(9):1528-34. Epub 2009 Apr 11.PMID: 19364505 [PubMed - indexed for MEDLINE]Related articles

Comparative assessment of the quadriceps and the diaphragm in patients with COPD.

Caron MA, Debigaré R, Dekhuijzen PN, Maltais F.

J Appl Physiol. 2009 Sep;107(3):952-61. Epub 2009 Apr 9. Review.PMID: 19359618 [PubMed - indexed for MEDLINE]Related articles

Reliability of ventilatory parameters during cycle ergometry in multicentre trials in COPD.

O'Donnell DE, Travers J, Webb KA, He Z, Lam YM, Hamilton A, Kesten S, Maltais F, Magnussen H.

Eur Respir J. 2009 Oct;34(4):866-74. Epub 2009 Mar 12.PMID: 19282342 [PubMed - in process]Related articles

Effects of home-based pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial.

Maltais F, Bourbeau J, Shapiro S, Lacasse Y, Perrault H, Baltzan M, Hernandez P, Rouleau M, Julien M, Parenteau S, Paradis B, Levy RD, Camp P, Lecours R, Audet R, Hutton B, Penrod JR, Picard D, Bernard S; Chronic Obstructive Pulmonary Disease Axis of Respiratory Health Network, Fonds de recherche en santé du Québec.

Ann Intern Med. 2008 Dec 16;149(12):869-78.PMID: 19075206 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of aerobic exercise training and irbesartan on blood pressure and heart rate variability in patients with chronic obstructive pulmonary disease.

Marquis K, Maltais F, Lacasse Y, Lacourciere Y, Fortin C, Poirier P.

Can Respir J. 2008 Oct;15(7):355-60.PMID: 18949104 [PubMed - indexed for MEDLINE]Related articlesFree article

[Cardiovascular manifestations in patients with COPD]

Marquis K, Maltais F, Poirier P.

Rev Mal Respir. 2008 Jun;25(6):663-73. Review. French. PMID: 18772824 [PubMed - indexed for MEDLINE]Related articles

Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation.

Debigaré R, Maltais F.

J Appl Physiol. 2008 Aug;105(2):764. No abstract available. PMID: 18678630 [PubMed - indexed for MEDLINE]Related articles

The major limitation to exercise performance in COPD is lower limb muscle dysfunction.

Debigaré R, Maltais F.

J Appl Physiol. 2008 Aug;105(2):751-3; discussion 755-7. No abstract available. PMID: 18678623 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhancing the benefits of pulmonary rehabilitation: doing more for a few or doing a little less for many?

Maltais F, Saey D, Debigaré R.

Am J Respir Crit Care Med. 2008 Aug 1;178(3):215-6. No abstract available. PMID: 18650569 [PubMed - indexed for MEDLINE]Related articlesFree article

Locus of symptom limitation and exercise response to bronchodilation in chronic obstructive pulmonary disease.

Deschênes D, Pepin V, Saey D, LeBlanc P, Maltais F.

J Cardiopulm Rehabil Prev. 2008 May-Jun;28(3):208-14.PMID: 18496322 [PubMed - indexed for MEDLINE]Related articles

Profiling of mRNA expression in quadriceps of patients with COPD and muscle wasting.

Debigaré R, Maltais F, Côté CH, Michaud A, Caron MA, Mofarrahi M, Leblanc P, Hussain SN.

COPD. 2008 Apr;5(2):75-84.PMID: 18415806 [PubMed - indexed for MEDLINE]Related articles

Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2008 update - highlights for primary care.

O'Donnell DE, Hernandez P, Kaplan A, Aaron S, Bourbeau J, Marciniuk D, Balter M, Ford G, Gervais A, Lacasse Y, Maltais F, Road J, Rocker G, Sin D, Sinuff T, Voduc N.

Can Respir J. 2008 Jan-Feb;15 Suppl A:1A-8A.PMID: 18292855 [PubMed - indexed for MEDLINE]Related articles

Neuromuscular electrical stimulation of the lower limbs in patients with chronic obstructive pulmonary disease.

Vivodtzev I, Lacasse Y, Maltais F.

J Cardiopulm Rehabil Prev. 2008 Mar-Apr;28(2):79-91. Review.PMID: 18360183 [PubMed - indexed for MEDLINE]Related articles

Point: Counterpoint - The major limitations to exercise performance in COPD.

Aliverti A Phd, Macklem PT, Debigare R, Maltais F, O'Donnell DE, Webb KA M Sc.

J Appl Physiol. 2008 Mar 13. [Epub ahead of print]PMID: 18339888 [PubMed - as supplied by publisher]Related articles

Increased distension stimulates distal capillary growth as well as expression of specific angiogenesis genes in fetal mouse lungs.

Cloutier M, Maltais F, Piedboeuf B.

Exp Lung Res. 2008 Mar;34(3):101-13.PMID: 18307120 [PubMed - indexed for MEDLINE]Related articles

Metabolic and inflammatory profile in obese patients with chronic obstructive pulmonary disease.

Poulain M, Doucet M, Drapeau V, Fournier G, Tremblay A, Poirier P, Maltais F.

Chron Respir Dis. 2008;5(1):35-41.PMID: 18303100 [PubMed - indexed for MEDLINE]Related articles

Identification of cellular processes that are rapidly modulated in response to tracheal occlusion within mice lungs.

Seaborn T, St-Amand J, Cloutier M, Tremblay MG, Maltais F, Dinel S, Moulin V, Khan PA, Piedboeuf B.

Pediatr Res. 2008 Feb;63(2):124-30.PMID: 18091360 [PubMed - indexed for MEDLINE]Related articles

Clinical management of chronic obstructive pulmonary disease and asthma in an obese patient.

Lessard A, Maltais F, Boulet LP.

Expert Opin Pharmacother. 2008 Jan;9(1):83-93. Review.PMID: 18076340 [PubMed - indexed for MEDLINE]Related articles

A randomized controlled trial to assess the efficacy of tiotropium in Canadian patients with chronic obstructive pulmonary disease.

Chan CK, Maltais F, Sigouin C, Haddon JM, Ford GT; SAFE Study Group.

Can Respir J. 2007 Nov-Dec;14(8):465-72.PMID: 18060091 [PubMed - indexed for MEDLINE]Related articlesFree article

Endurance shuttle walking test: responsiveness to salmeterol in COPD.

Brouillard C, Pepin V, Milot J, Lacasse Y, Maltais F.

Eur Respir J. 2008 Mar;31(3):579-84. Epub 2007 Dec 5.PMID: 18057052 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of diabetes, chronic heart failure, congenital heart disease and chronic obstructive pulmonary disease on acute and chronic exercise responses.

Brassard P, Ferland A, Marquis K, Maltais F, Jobin J, Poirier P.

Can J Cardiol. 2007 Oct;23 Suppl B:89B-96B. Review. Erratum in: Can J Cardiol. 2009 Mar;25(3):140. PMID: 17932595 [PubMed - indexed for MEDLINE]Related articles

Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2007 update.

O'Donnell DE, Aaron S, Bourbeau J, Hernandez P, Marciniuk DD, Balter M, Ford G, Gervais A, Goldstein R, Hodder R, Kaplan A, Keenan S, Lacasse Y, Maltais F, Road J, Rocker G, Sin D, Sinuff T, Voduc N.

Can Respir J. 2007 Sep;14 Suppl B:5B-32B. Review.PMID: 17885691 [PubMed - indexed for MEDLINE]Related articles

Short-term response to tracheal occlusion during perinatal lung development in mice.

Seaborn T, Khan PA, Cloutier M, Maltais F, Piedboeuf B.

Exp Lung Res. 2007 Oct-Nov;33(8-9):441-57.PMID: 17994371 [PubMed - indexed for MEDLINE]Related articles

Assessing the impact of pulmonary rehabilitation on functional status in COPD.

Laviolette L, Bourbeau J, Bernard S, Lacasse Y, Pepin V, Breton MJ, Baltzan M, Rouleau M, Maltais F.

Thorax. 2008 Feb;63(2):115-21. Epub 2007 Sep 27.PMID: 17901158 [PubMed - indexed for MEDLINE]Related articles

Nocturnal oxygen therapy in patients with chronic obstructive pulmonary disease: a survey of Canadian respirologists.

Lacasse Y, Sériès F, Martin S, Maltais F.

Can Respir J. 2007 Sep;14(6):343-8.PMID: 17885694 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise capacity in chronic obstructive pulmonary disease: mechanisms of limitation.

Pepin V, Saey D, Laviolette L, Maltais F.

COPD. 2007 Sep;4(3):195-204. Review.PMID: 17729063 [PubMed - indexed for MEDLINE]Related articles

Self-administered prescriptions of oral steroids and antibiotics in chronic obstructive pulmonary disease: are we doing more harm than good?

Beaulieu-Genest L, Chrétien D, Maltais F, Pelletier K, Parent JG, Lacasse Y.

Chron Respir Dis. 2007;4(3):143-7.PMID: 17711913 [PubMed - indexed for MEDLINE]Related articles

Counting, analysing and reporting exacerbations of COPD in randomised controlled trials.

Aaron SD, Fergusson D, Marks GB, Suissa S, Vandemheen KL, Doucette S, Maltais F, Bourbeau JF, Goldstein RS, Balter M, O'Donnell D, Fitzgerald M; Canadian Thoracic Society/Canadian Respiratory Clinical Research Consortium.

Thorax. 2008 Feb;63(2):122-8. Epub 2007 Aug 16. Review.PMID: 17702790 [PubMed - indexed for MEDLINE]Related articles

Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: a randomised controlled trial.

Bourbeau J, Christodoulopoulos P, Maltais F, Yamauchi Y, Olivenstein R, Hamid Q.

Thorax. 2007 Nov;62(11):938-43. Epub 2007 Jun 8.PMID: 17557771 [PubMed - indexed for MEDLINE]Related articles

Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.

Doucet M, Russell AP, Léger B, Debigaré R, Joanisse DR, Caron MA, LeBlanc P, Maltais F.

Am J Respir Crit Care Med. 2007 Aug 1;176(3):261-9. Epub 2007 May 3.PMID: 17478621 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic obstructive pulmonary disease in women.

Laviolette L, Lacasse Y, Doucet M, Lacasse M, Marquis K, Saey D, Leblanc P, Maltais F.

Can Respir J. 2007 Mar;14(2):93-8.PMID: 17372636 [PubMed - indexed for MEDLINE]Related articlesFree article

Postoperative outcome after coronary artery bypass grafting in chronic obstructive pulmonary disease.

Manganas H, Lacasse Y, Bourgeois S, Perron J, Dagenais F, Maltais F.

Can Respir J. 2007 Jan-Feb;14(1):19-24.PMID: 17315054 [PubMed - indexed for MEDLINE]Related articlesFree article

Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial.

Aaron SD, Vandemheen KL, Fergusson D, Maltais F, Bourbeau J, Goldstein R, Balter M, O'Donnell D, McIvor A, Sharma S, Bishop G, Anthony J, Cowie R, Field S, Hirsch A, Hernandez P, Rivington R, Road J, Hoffstein V, Hodder R, Marciniuk D, McCormack D, Fox G, Cox G, Prins HB, Ford G, Bleskie D, Doucette S, Mayers I, Chapman K, Zamel N, FitzGerald M; Canadian Thoracic Society/Canadian Respiratory Clinical Research Consortium.

Ann Intern Med. 2007 Apr 17;146(8):545-55. Epub 2007 Feb 19.PMID: 17310045 [PubMed - indexed for MEDLINE]Related articlesFree article

Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors.

Aronov AM, Baker C, Bemis GW, Cao J, Chen G, Ford PJ, Germann UA, Green J, Hale MR, Jacobs M, Janetka JW, Maltais F, Martinez-Botella G, Namchuk MN, Straub J, Tang Q, Xie X.

J Med Chem. 2007 Mar 22;50(6):1280-7. Epub 2007 Feb 15.PMID: 17300186 [PubMed - indexed for MEDLINE]Related articles

Six-minute walking versus shuttle walking: responsiveness to bronchodilation in chronic obstructive pulmonary disease.

Pepin V, Brodeur J, Lacasse Y, Milot J, Leblanc P, Whittom F, Maltais F.

Thorax. 2007 Apr;62(4):291-8. Epub 2006 Nov 10.PMID: 17099077 [PubMed - indexed for MEDLINE]Related articles

Synergetic interactions between rehabilitation and pharmacotherapy in COPD.

Pepin V, Laviolette L, Saey D, Maltais F.

Clin Invest Med. 2006 Jun;29(3):170-7. Review.PMID: 17058437 [PubMed - indexed for MEDLINE]Related articles

American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation.

Nici L, Donner C, Wouters E, Zuwallack R, Ambrosino N, Bourbeau J, Carone M, Celli B, Engelen M, Fahy B, Garvey C, Goldstein R, Gosselink R, Lareau S, MacIntyre N, Maltais F, Morgan M, O'Donnell D, Prefault C, Reardon J, Rochester C, Schols A, Singh S, Troosters T; ATS/ERS Pulmonary Rehabilitation Writing Committee.

Am J Respir Crit Care Med. 2006 Jun 15;173(12):1390-413. No abstract available. PMID: 16760357 [PubMed - indexed for MEDLINE]Related articlesFree article

Got a match? Home oxygen therapy in current smokers.

Lacasse Y, LaForge J, Maltais F.

Thorax. 2006 May;61(5):374-5. No abstract available. PMID: 16648351 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle endurance and muscle metabolism in patients with chronic heart failure.

Brassard P, Maltais F, Noel M, Doyon JF, LeBlanc P, Allaire J, Simard C, Leblanc MH, Poirier P, Jobin J.

Can J Cardiol. 2006 Apr;22(5):387-92.PMID: 16639473 [PubMed - indexed for MEDLINE]Related articlesFree article