PubMed

A Dosing/Cross-Development Study of the Multikinase Inhibitor Sorafenib in Patients With Pulmonary Arterial Hypertension.

Gomberg-Maitland M, Maitland ML, Barst RJ, Sugeng L, Coslet S, Perrino TJ, Bond L, Lacouture ME, Archer SL, Ratain MJ.

Clin Pharmacol Ther. . [Epub ahead of print]PMID: 20010555 [PubMed - as supplied by publisher]Related articles

Carboplatin and Paclitaxel in Combination With Either Vorinostat or Placebo for First-Line Therapy of Advanced Non-Small-Cell Lung Cancer.

Ramalingam SS, Maitland ML, Frankel P, Argiris AE, Koczywas M, Gitlitz B, Thomas S, Espinoza-Delgado I, Vokes EE, Gandara DR, Belani CP.

J Clin Oncol. 2009 Nov 23. [Epub ahead of print]PMID: 19933908 [PubMed - as supplied by publisher]Related articles

Other Paradigms: Better Treatments Are Identified by Better Trials: The Value of Randomized Phase II Studies.

Sharma MR, Maitland ML, Ratain MJ.

Cancer J. 2009 Sep-Oct;15(5):426-30.PMID: 19826363 [PubMed - in process]Related articles

Ambulatory monitoring detects sorafenib-induced blood pressure elevations on the first day of treatment.

Maitland ML, Kasza KE, Karrison T, Moshier K, Sit L, Black HR, Undevia SD, Stadler WM, Elliott WJ, Ratain MJ.

Clin Cancer Res. 2009 Oct 1;15(19):6250-7. Epub 2009 Sep 22.PMID: 19773379 [PubMed - in process]Related articles

Inflammation, growth factors, and pulmonary vascular remodeling.

Hassoun PM, Mouthon L, Barberà JA, Eddahibi S, Flores SC, Grimminger F, Jones PL, Maitland ML, Michelakis ED, Morrell NW, Newman JH, Rabinovitch M, Schermuly R, Stenmark KR, Voelkel NF, Yuan JX, Humbert M.

J Am Coll Cardiol. 2009 Jun 30;54(1 Suppl):S10-9. Review.PMID: 19555853 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular toxicities: clues to optimal administration of vascular endothelial growth factor signaling pathway inhibitors.

Snider KL, Maitland ML.

Target Oncol. 2009 Apr;4(2):67-76. Epub 2009 Apr 17. Review.PMID: 19373440 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular toxicity of new agents.

Maitland ML.

Clin Adv Hematol Oncol. 2008 Sep;6(9):657-9. No abstract available. PMID: 18827788 [PubMed - indexed for MEDLINE]Related articles

Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension.

Moreno-Vinasco L, Gomberg-Maitland M, Maitland ML, Desai AA, Singleton PA, Sammani S, Sam L, Liu Y, Husain AN, Lang RM, Ratain MJ, Lussier YA, Garcia JG.

Physiol Genomics. 2008 Apr 22;33(2):278-91. Epub 2008 Feb 26.PMID: 18303084 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.

Archer SL, Gomberg-Maitland M, Maitland ML, Rich S, Garcia JG, Weir EK.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H570-8. Epub 2007 Dec 14. Review.PMID: 18083891 [PubMed - indexed for MEDLINE]Related articlesFree article

Interpreting P values in pharmacogenetic studies: a call for process and perspective.

Maitland ML, Ratain MJ, Cox NJ.

J Clin Oncol. 2007 Oct 10;25(29):4513-5. No abstract available. PMID: 17925544 [PubMed - indexed for MEDLINE]Related articles

Design of phase II cancer trials using a continuous endpoint of change in tumor size: application to a study of sorafenib and erlotinib in non small-cell lung cancer.

Karrison TG, Maitland ML, Stadler WM, Ratain MJ.

J Natl Cancer Inst. 2007 Oct 3;99(19):1455-61. Epub 2007 Sep 25. Erratum in: J Natl Cancer Inst. 2007 Dec 5;99(23):1819. PMID: 17895472 [PubMed - indexed for MEDLINE]Related articlesFree article

Terminal ballistics of kinase inhibitors: there are no magic bullets.

Maitland ML, Ratain MJ.

Ann Intern Med. 2006 Nov 7;145(9):702-3. No abstract available. PMID: 17088586 [PubMed - indexed for MEDLINE]Related articlesFree article

Diffuse alveolar damage after a single dose of topotecan in a patient with pulmonary fibrosis and small cell lung cancer.

Maitland ML, Wilcox R, Hogarth DK, Desai AA, Caligiuri P, Abrahams C, Salgia R.

Lung Cancer. 2006 Nov;54(2):243-5. Epub 2006 Sep 1.PMID: 16949700 [PubMed - indexed for MEDLINE]Related articles

TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy?

Maitland ML, Vasisht K, Ratain MJ.

Trends Pharmacol Sci. 2006 Aug;27(8):432-7. Epub 2006 Jul 3. Review.PMID: 16815558 [PubMed - indexed for MEDLINE]Related articles

Interpreting disparate responses to cancer therapy: the role of human population genetics.

Maitland ML, DiRienzo A, Ratain MJ.

J Clin Oncol. 2006 May 10;24(14):2151-7. Review.PMID: 16682733 [PubMed - indexed for MEDLINE]Related articles

Comparative genomics analysis of human sequence variation in the UGT1A gene cluster.

Maitland ML, Grimsley C, Kuttab-Boulos H, Witonsky D, Kasza KE, Yang L, Roe BA, Di Rienzo A.

Pharmacogenomics J. 2006 Jan-Feb;6(1):52-62.PMID: 16314881 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms of adrenergic receptors and the risk of heart failure.

Maitland ML, Gomberg-Maitland M.

N Engl J Med. 2003 Jan 30;348(5):468-70; author reply 468-70. No abstract available. PMID: 12557866 [PubMed - indexed for MEDLINE]Related articles

Mycobacterial infection of macrophages results in membrane-permeable phagosomes.

Teitelbaum R, Cammer M, Maitland ML, Freitag NE, Condeelis J, Bloom BR.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15190-5.PMID: 10611360 [PubMed - indexed for MEDLINE]Related articlesFree article