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    Results: 34

    1.

    Glucose-oxidized low-density lipoproteins enhance insulin-like growth factor I-stimulated smooth muscle cell proliferation by inhibiting integrin-associated protein cleavage.

    Allen LB, Capps BE, Miller EC, Clemmons DR, Maile LA.

    Endocrinology. 2009 Mar;150(3):1321-9. Epub 2008 Oct 30.PMID: 18974270 [PubMed - indexed for MEDLINE]Related articles

    2.

    Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo.

    Maile LA, Capps BE, Miller EC, Aday AW, Clemmons DR.

    Diabetes. 2008 Oct;57(10):2637-43. Epub 2008 Jul 15.PMID: 18633106 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Modulation of integrin antagonist signaling by ligand binding of the heparin-binding domain of vitronectin to the alphaVbeta3 integrin.

    Maile LA, Aday AW, Busby WH, Sanghani R, Veluvolu U, Clemmons DR.

    J Cell Biochem. 2008 Oct 1;105(2):437-46.PMID: 18615592 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.

    Radhakrishnan Y, Maile LA, Ling Y, Graves LM, Clemmons DR.

    J Biol Chem. 2008 Jun 13;283(24):16320-31. Epub 2008 Apr 16.PMID: 18420583 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.

    Maile LA, Capps BE, Miller EC, Allen LB, Veluvolu U, Aday AW, Clemmons DR.

    Mol Endocrinol. 2008 May;22(5):1226-37. Epub 2008 Feb 21.PMID: 18292237 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Regulation of igf-I signaling in retinal endothelial cells by hyperglycemia.

    Miller EC, Capps BE, Sanghani RR, Clemmons DR, Maile LA.

    Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3878-87.PMID: 17652764 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Expression of the human beta3 integrin subunit in mouse smooth muscle cells enhances IGF-I-stimulated signaling and proliferation.

    Xi G, Maile LA, Yoo SE, Clemmons DR.

    J Cell Physiol. 2008 Feb;214(2):306-15.PMID: 17607710 [PubMed - indexed for MEDLINE]Related articles

    8.

    Role of the integrin alphaVbeta3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress.

    Clemmons DR, Maile LA, Ling Y, Yarber J, Busby WH.

    Growth Horm IGF Res. 2007 Aug;17(4):265-70. Epub 2007 Apr 6. Review.PMID: 17412627 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.

    Maile LA, Capps BE, Ling Y, Xi G, Clemmons DR.

    Endocrinology. 2007 May;148(5):2435-43. Epub 2007 Jan 25.PMID: 17255202 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    The heparin binding domain of vitronectin is the region that is required to enhance insulin-like growth factor-I signaling.

    Maile LA, Busby WH, Sitko K, Capps BE, Sergent T, Badley-Clarke J, Ling Y, Clemmons DR.

    Mol Endocrinol. 2006 Apr;20(4):881-92. Epub 2005 Dec 1.PMID: 16322097 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells.

    Kwon M, Ling Y, Maile LA, Badley-Clark J, Clemmons DR.

    Endocrinology. 2006 Mar;147(3):1458-65. Epub 2005 Nov 23.PMID: 16306077 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Insulin-like growth factor-I signaling in smooth muscle cells is regulated by ligand binding to the 177CYDMKTTC184 sequence of the beta3-subunit of alphaVbeta3.

    Maile LA, Busby WH, Sitko K, Capps BE, Sergent T, Badley-Clarke J, Clemmons DR.

    Mol Endocrinol. 2006 Feb;20(2):405-13. Epub 2005 Sep 29.PMID: 16195248 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.

    Ling Y, Maile LA, Lieskovska J, Badley-Clarke J, Clemmons DR.

    Mol Biol Cell. 2005 Jul;16(7):3353-64. Epub 2005 May 11.PMID: 15888547 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Insulin-like growth factor binding protein-5 (IGFBP-5) interacts with thrombospondin-1 to induce negative regulatory effects on IGF-I actions.

    Moralez AM, Maile LA, Clarke J, Busby WH Jr, Clemmons DR.

    J Cell Physiol. 2005 May;203(2):328-34.PMID: 15700281 [PubMed - indexed for MEDLINE]Related articles

    15.

    DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells.

    Ling Y, Maile LA, Badley-Clarke J, Clemmons DR.

    J Biol Chem. 2005 Feb 4;280(5):3151-8. Epub 2004 Nov 15.PMID: 15546884 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs.

    Clemmons DR, Maile LA.

    Mol Endocrinol. 2005 Jan;19(1):1-11. Epub 2004 Nov 4. Review.PMID: 15528274 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Integrin-associated protein binding domain of thrombospondin-1 enhances insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.

    Maile LA, Clemmons DR.

    Circ Res. 2003 Nov 14;93(10):925-31. Epub 2003 Oct 16.PMID: 14563713 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    The association between integrin-associated protein and SHPS-1 regulates insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.

    Maile LA, Badley-Clarke J, Clemmons DR.

    Mol Biol Cell. 2003 Sep;14(9):3519-28. Epub 2003 May 29.PMID: 12972543 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for embrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor.

    Ling Y, Maile LA, Clemmons DR.

    Mol Endocrinol. 2003 Sep;17(9):1824-33. Epub 2003 Jun 5.PMID: 12791772 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling.

    Clemmons DR, Maile LA.

    Endocrinology. 2003 May;144(5):1664-70. Review.PMID: 12697669 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor.

    Maile LA, Clemmons DR.

    Endocrinology. 2002 Nov;143(11):4259-64.PMID: 12399420 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Regulation of insulin-like growth factor I receptor dephosphorylation by SHPS-1 and the tyrosine phosphatase SHP-2.

    Maile LA, Clemmons DR.

    J Biol Chem. 2002 Mar 15;277(11):8955-60. Epub 2002 Jan 4.PMID: 11779860 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Insulin-like growth factor I increases alpha Vbeta 3 affinity by increasing the amount of integrin-associated protein that is associated with non-raft domains of the cellular membrane.

    Maile LA, Imai Y, Clarke JB, Clemmons DR.

    J Biol Chem. 2002 Jan 18;277(3):1800-5. Epub 2001 Nov 13.PMID: 11707450 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Structural analysis of the role of the beta 3 subunit of the alpha V beta 3 integrin in IGF-I signaling.

    Maile LA, Badley-Clarke J, Clemmons DR.

    J Cell Sci. 2001 Apr;114(Pt 7):1417-25.PMID: 11257007 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Endogenous IGFBP-3 is protected from inducible IGFBP-3 protease activity in normal adult serum.

    Maile LA, Whellams EJ, Holly JM.

    Growth Horm IGF Res. 2000 Apr;10(2):71-7.PMID: 10931744 [PubMed - indexed for MEDLINE]Related articles

    26.

    Alterations in insulin-like growth factor binding protein-3 proteolysis and complex formation in the arthritic joint.

    Whellams EJ, Maile LA, Fernihough JK, Billingham ME, Holly JM.

    J Endocrinol. 2000 Jun;165(3):545-56.PMID: 10828838 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    The role of cell surface attachment and proteolysis in the insulin-like growth factor (IGF)-independent effects of IGF-binding protein-3 on apoptosis in breast epithelial cells.

    Maile LA, Gill ZP, Perks CM, Holly JM.

    Endocrinology. 1999 Sep;140(9):4040-5.PMID: 10465274 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Insulin-like growth factor binding protein (IGFBP) proteolysis: occurrence, identification, role and regulation.

    Maile LA, Holly JM.

    Growth Horm IGF Res. 1999 Apr;9(2):85-95. Review. No abstract available. PMID: 10373341 [PubMed - indexed for MEDLINE]Related articles

    29.

    Active and inhibitory components of the insulin-like growth factor binding protein-3 protease system in adult serum, interstitial, and synovial fluid.

    Maile LA, Xu S, Cwyfan-Hughes SC, Fernihough JK, Pell JM, Holly JM.

    Endocrinology. 1998 Dec;139(12):4772-81.PMID: 9832413 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    Ovarian dysfunction in endometriosis-associated and unexplained infertility.

    Cahill DJ, Wardle PG, Maile LA, Harlow CR, Hull MG.

    J Assist Reprod Genet. 1997 Nov;14(10):554-7.PMID: 9447453 [PubMed - indexed for MEDLINE]Related articles

    31.

    Antibiotic treatment based on seminal cultures from asymptomatic male partners in in-vitro fertilization is unnecessary and may be detrimental.

    Liversedge NH, Jenkins JM, Keay SD, McLaughlin EA, Al-Sufyan H, Maile LA, Joels LA, Hull MG.

    Hum Reprod. 1996 Jun;11(6):1227-31.PMID: 8671429 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Reduced preovulatory granulosa cell steroidogenesis in women with endometriosis.

    Harlow CR, Cahill DJ, Maile LA, Talbot WM, Mears J, Wardle PG, Hull MG.

    J Clin Endocrinol Metab. 1996 Jan;81(1):426-9.PMID: 8550788 [PubMed - indexed for MEDLINE]Related articles

    33.

    Pituitary-ovarian dysfunction as a cause for endometriosis-associated and unexplained infertility.

    Cahill DJ, Wardle PG, Maile LA, Harlow CR, Hull MG.

    Hum Reprod. 1995 Dec;10(12):3142-46.PMID: 8822432 [PubMed - indexed for MEDLINE]Related articles

    34.

    Time-dependent effects of transforming growth factor alpha on aromatase activity in human granulosa cells.

    Harlow CR, Cahill DJ, Maile LA, Wardle PG, Hull MG.

    Hum Reprod. 1995 Oct;10(10):2554-9.PMID: 8567769 [PubMed - indexed for MEDLINE]Related articles

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