PubMed

Gene Therapy for Leber's Congenital Amaurosis is Safe and Effective Through 1.5 Years After Vector Administration.

Simonelli F, Maguire AM, Testa F, Pierce EA, Mingozzi F, Bennicelli JL, Rossi S, Marshall K, Banfi S, Surace EM, Sun J, Redmond TM, Zhu X, Shindler KS, Ying GS, Ziviello C, Acerra C, Wright JF, McDonnell JW, High KA, Bennett J, Auricchio A.

Mol Ther. 2009 Dec 1. [Epub ahead of print]PMID: 19953081 [PubMed - as supplied by publisher]Related articles

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial.

Maguire AM, High KA, Auricchio A, Wright JF, Pierce EA, Testa F, Mingozzi F, Bennicelli JL, Ying GS, Rossi S, Fulton A, Marshall KA, Banfi S, Chung DC, Morgan JI, Hauck B, Zelenaia O, Zhu X, Raffini L, Coppieters F, De Baere E, Shindler KS, Volpe NJ, Surace EM, Acerra C, Lyubarsky A, Redmond TM, Stone E, Sun J, McDonnell JW, Leroy BP, Simonelli F, Bennett J.

Lancet. 2009 Nov 7;374(9701):1597-605. Epub 2009 Oct 23.PMID: 19854499 [PubMed - in process]Related articles

Other complications and associated conditions with diabetes in children and adolescents.

Kordonouri O, Maguire AM, Knip M, Schober E, Lorini R, Holl RW, Donaghue KC.

Pediatr Diabetes. 2009 Sep;10 Suppl 12:204-10. No abstract available. PMID: 19754631 [PubMed - in process]Related articles

Sick day management in children and adolescents with diabetes.

Brink S, Laffel L, Likitmaskul S, Liu L, Maguire AM, Olsen B, Silink M, Hanas R.

Pediatr Diabetes. 2009 Sep;10 Suppl 12:146-53. No abstract available. PMID: 19754625 [PubMed - in process]Related articles

Recent advances in ocular gene therapy.

Chung DC, Lee V, Maguire AM.

Curr Opin Ophthalmol. 2009 Sep;20(5):377-81. Review.PMID: 19667988 [PubMed - indexed for MEDLINE]Related articles

Cortisol response to general anaesthesia for medical imaging in children.

Rains P, Rampersad N, De Lima J, Murrell D, Kinchington D, Lee J, Maguire AM, Donaghue K.

Clin Endocrinol (Oxf). 2009 Mar 28. [Epub ahead of print]PMID: 19508604 [PubMed - as supplied by publisher]Related articles

Delayed referral of new-onset type 1 diabetes increases the risk of diabetic ketoacidosis.

Craig ME, Wong CH, Alexander J, Maguire AM, Silink M.

Med J Aust. 2009 Feb 16;190(4):219. No abstract available. PMID: 19220193 [PubMed - indexed for MEDLINE]Related articles

Contexts and control operations used in accessing list-specific, generalized, and semantic memories.

Humphreys MS, Murray KL, Maguire AM.

Cogn Psychol. 2009 May;58(3):311-37. Epub 2008 Nov 11.PMID: 19006790 [PubMed - indexed for MEDLINE]Related articles

Management of adrenal insufficiency during the stress of medical illness and surgery.Comment.

Maguire AM, Craig ME, Cowell CT.

Med J Aust. 2008 Sep 15;189(6):350. No abstract available. PMID: 18953704 [PubMed - indexed for MEDLINE]Related articles

Safety and efficacy of gene transfer for Leber's congenital amaurosis.

Maguire AM, Simonelli F, Pierce EA, Pugh EN Jr, Mingozzi F, Bennicelli J, Banfi S, Marshall KA, Testa F, Surace EM, Rossi S, Lyubarsky A, Arruda VR, Konkle B, Stone E, Sun J, Jacobs J, Dell'Osso L, Hertle R, Ma JX, Redmond TM, Zhu X, Hauck B, Zelenaia O, Shindler KS, Maguire MG, Wright JF, Volpe NJ, McDonnell JW, Auricchio A, High KA, Bennett J.

N Engl J Med. 2008 May 22;358(21):2240-8. Epub 2008 Apr 27.PMID: 18441370 [PubMed - indexed for MEDLINE]Related articlesFree article

Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer.

Bennicelli J, Wright JF, Komaromy A, Jacobs JB, Hauck B, Zelenaia O, Mingozzi F, Hui D, Chung D, Rex TS, Wei Z, Qu G, Zhou S, Zeiss C, Arruda VR, Acland GM, Dell'Osso LF, High KA, Maguire AM, Bennett J.

Mol Ther. 2008 Mar;16(3):458-65. Epub 2008 Jan 22.PMID: 18209734 [PubMed - indexed for MEDLINE]Related articles

Evaluation of adrenal function using the human corticotrophin-releasing hormone test, low dose Synacthen test and 9am cortisol level in children and adolescents with central adrenal insufficiency.

Maguire AM, Biesheuvel CJ, Ambler GR, Moore B, McLean M, Cowell CT.

Clin Endocrinol (Oxf). 2008 May;68(5):683-91. Epub 2007 Dec 7.PMID: 18070143 [PubMed - indexed for MEDLINE]Related articles

Sick day management in children and adolescents with diabetes.

Brink S, Laffel L, Likitmaskul S, Liu L, Maguire AM, Olsen B, Silink M, Hanas R; International Society for Pediatric and Adolescent Diabetes (ISPAD).

Pediatr Diabetes. 2007 Dec;8(6):401-7. No abstract available. PMID: 18036069 [PubMed - indexed for MEDLINE]Related articles

Salivary cortisol to assess the hypothalamic-pituitary-adrenal axis in healthy children under 3 years old.

Maguire AM, Cowell CT.

J Pediatr (Rio J). 2007 Jul-Aug;83(4):383-4; author reply 384-6. Review. No abstract available. PMID: 17676242 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolonged hypocortisolemia in hydrocortisone replacement regimens in adrenocorticotrophic hormone deficiency.

Maguire AM, Ambler GR, Moore B, McLean M, Falleti MG, Cowell CT.

Pediatrics. 2007 Jul;120(1):e164-71. Epub 2007 Jun 18.PMID: 17576782 [PubMed - indexed for MEDLINE]Related articlesFree article

ISPAD Clinical Practice Consensus Guidelines 2006-2007. Other complications and associated conditions.

Kordonouri O, Maguire AM, Knip M, Schober E, Lorini R, Holl RW, Donaghue KC; International Society for Pediatric and Adolescent Diabetes.

Pediatr Diabetes. 2007 Jun;8(3):171-6. No abstract available. PMID: 17550428 [PubMed - indexed for MEDLINE]Related articles

Laser scanning imaging for macular disease: a report by the American Academy of Ophthalmology.

McDonald HR, Williams GA, Scott IU, Haller JA, Maguire AM, Marcus DM; American Academy of Ophthalmology; Ophthalmic Technology Assessment Committee Retina Panel.

Ophthalmology. 2007 Jun;114(6):1221-8. Epub 2007 Apr 26.PMID: 17466377 [PubMed - indexed for MEDLINE]Related articles

The clinical utility of alternative, less invasive sampling techniques in the assessment of oral hydrocortisone therapy in children and adolescents with hypopituitarism.

Maguire AM, Ambler GR, Moore B, Waite K, McLean M, Cowell CT.

Eur J Endocrinol. 2007 Apr;156(4):471-6.PMID: 17389462 [PubMed - indexed for MEDLINE]Related articlesFree article

Autonomic nerve testing predicts the development of complications: a 12-year follow-up study.

Maguire AM, Craig ME, Craighead A, Chan AK, Cusumano JM, Hing SJ, Silink M, Howard NJ, Donaghue KC.

Diabetes Care. 2007 Jan;30(1):77-82. Erratum in: Diabetes Care. 2007 Apr;30(4):1035. PMID: 17192337 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of Susac syndrome with gamma globulin and corticosteroids.

Fox RJ, Costello F, Judkins AR, Galetta SL, Maguire AM, Leonard B, Markowitz CE.

J Neurol Sci. 2006 Dec 21;251(1-2):17-22. Epub 2006 Oct 17.PMID: 17052732 [PubMed - indexed for MEDLINE]Related articles

Total exudative retinal detachment in coats disease: biochemical analysis of the subretinal exudate.

Hsu J, Forbes B, Maguire AM.

Retina. 2006 Sep;26(7):831-3. No abstract available. PMID: 16963863 [PubMed - indexed for MEDLINE]Related articles

Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis.

Jacobson SG, Boye SL, Aleman TS, Conlon TJ, Zeiss CJ, Roman AJ, Cideciyan AV, Schwartz SB, Komaromy AM, Doobrajh M, Cheung AY, Sumaroka A, Pearce-Kelling SE, Aguirre GD, Kaushal S, Maguire AM, Flotte TR, Hauswirth WW.

Hum Gene Ther. 2006 Aug;17(8):845-58.PMID: 16942444 [PubMed - indexed for MEDLINE]Related articles

Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection.

Jacobson SG, Acland GM, Aguirre GD, Aleman TS, Schwartz SB, Cideciyan AV, Zeiss CJ, Komaromy AM, Kaushal S, Roman AJ, Windsor EA, Sumaroka A, Pearce-Kelling SE, Conlon TJ, Chiodo VA, Boye SL, Flotte TR, Maguire AM, Bennett J, Hauswirth WW.

Mol Ther. 2006 Jun;13(6):1074-84. Epub 2006 Apr 27.PMID: 16644289 [PubMed - indexed for MEDLINE]Related articles

Variability in Guedel airway design.

Davies JA, Maguire AM.

Anaesthesia. 2006 Mar;61(3):297-8. No abstract available. PMID: 16480360 [PubMed - indexed for MEDLINE]Related articles

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.

Acland GM, Aguirre GD, Bennett J, Aleman TS, Cideciyan AV, Bennicelli J, Dejneka NS, Pearce-Kelling SE, Maguire AM, Palczewski K, Hauswirth WW, Jacobson SG.

Mol Ther. 2005 Dec;12(6):1072-82. Epub 2005 Oct 14.PMID: 16226919 [PubMed - indexed for MEDLINE]Related articles

Idiopathic epiretinal membranes: ultrastructural characteristics and clinicopathologic correlation. 1989.

Smiddy WE, Maguire AM, Green WR, Michels RG, de la Cruz Z, Enger C, Jaeger M, Rice TA.

Retina. 2005 Jul-Aug;25(5 Suppl):811-20; discussion 821. No abstract available. PMID: 16049366 [PubMed - indexed for MEDLINE]Related articles

Transmission of retinal laser wavelengths through blood.

Stoltz RA, Glazer-Hockstein C, Tolentino MJ, Maguire AM.

Retina. 2005 Jun;25(4):498-502.PMID: 15933598 [PubMed - indexed for MEDLINE]Related articles

Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.

Jacobson SG, Aleman TS, Cideciyan AV, Sumaroka A, Schwartz SB, Windsor EA, Traboulsi EI, Heon E, Pittler SJ, Milam AH, Maguire AM, Palczewski K, Stone EM, Bennett J.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6177-82. Epub 2005 Apr 18.PMID: 15837919 [PubMed - indexed for MEDLINE]Related articlesFree article

Nonhuman primate models for diabetic ocular neovascularization using AAV2-mediated overexpression of vascular endothelial growth factor.

Lebherz C, Maguire AM, Auricchio A, Tang W, Aleman TS, Wei Z, Grant R, Cideciyan AV, Jacobson SG, Wilson JM, Bennett J.

Diabetes. 2005 Apr;54(4):1141-9.PMID: 15793254 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates.

Lebherz C, Auricchio A, Maguire AM, Rivera VM, Tang W, Grant RL, Clackson T, Bennett J, Wilson JM.

Hum Gene Ther. 2005 Feb;16(2):178-86.PMID: 15761258 [PubMed - indexed for MEDLINE]Related articles

Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress.

Rex TS, Tsui I, Hahn P, Maguire AM, Duan D, Bennett J, Dunaief JL.

Hum Gene Ther. 2004 Oct;15(10):960-7.PMID: 15585111 [PubMed - indexed for MEDLINE]Related articles

Effect of over-expression of pigment epithelium derived factor (PEDF) on developing retinal vasculature in the mouse.

Wong WT, Rex TS, Auricchio A, Maguire AM, Chung D, Tang W, Bennett J.

Mol Vis. 2004 Nov 8;10:837-44.PMID: 15547489 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration.

Rex TS, Allocca M, Domenici L, Surace EM, Maguire AM, Lyubarsky A, Cellerino A, Bennett J, Auricchio A.

Mol Ther. 2004 Nov;10(5):855-61.PMID: 15509503 [PubMed - indexed for MEDLINE]Related articles

Müller cell transduction by AAV2 in normal and degenerative retinas.

Liang FQ, Surace E, Dejneka NS, Maguire AM, Bennett J.

Adv Exp Med Biol. 2003;533:439-45. No abstract available. PMID: 15180296 [PubMed - indexed for MEDLINE]Related articles

Single-field fundus photography for diabetic retinopathy screening: a report by the American Academy of Ophthalmology.

Williams GA, Scott IU, Haller JA, Maguire AM, Marcus D, McDonald HR.

Ophthalmology. 2004 May;111(5):1055-62. Review.PMID: 15121388 [PubMed - indexed for MEDLINE]Related articles

In utero gene therapy rescues vision in a murine model of congenital blindness.

Dejneka NS, Surace EM, Aleman TS, Cideciyan AV, Lyubarsky A, Savchenko A, Redmond TM, Tang W, Wei Z, Rex TS, Glover E, Maguire AM, Pugh EN Jr, Jacobson SG, Bennett J.

Mol Ther. 2004 Feb;9(2):182-8.PMID: 14759802 [PubMed - indexed for MEDLINE]Related articles

Mutations in ABCA4 result in accumulation of lipofuscin before slowing of the retinoid cycle: a reappraisal of the human disease sequence.

Cideciyan AV, Aleman TS, Swider M, Schwartz SB, Steinberg JD, Brucker AJ, Maguire AM, Bennett J, Stone EM, Jacobson SG.

Hum Mol Genet. 2004 Mar 1;13(5):525-34. Epub 2004 Jan 6.PMID: 14709597 [PubMed - indexed for MEDLINE]Related articlesFree article

Atypical presentation of bone marrow transplant retinopathy.

Demirci H, Shields JA, Shields CL, Maguire AM.

J Pediatr Ophthalmol Strabismus. 2003 Nov-Dec;40(6):361-3. No abstract available. PMID: 14655986 [PubMed - indexed for MEDLINE]Related articles

What you get out of memory depends on the question you ask.

Humphreys MS, Dennis S, Maguire AM, Reynolds K, Bolland SW, Hughes JD.

J Exp Psychol Learn Mem Cogn. 2003 Sep;29(5):797-812.PMID: 14516214 [PubMed - indexed for MEDLINE]Related articles

Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction.

Surace EM, Auricchio A, Reich SJ, Rex T, Glover E, Pineles S, Tang W, O'Connor E, Lyubarsky A, Savchenko A, Pugh EN Jr, Maguire AM, Wilson JM, Bennett J.

J Virol. 2003 Jul;77(14):7957-63.PMID: 12829835 [PubMed - indexed for MEDLINE]Related articlesFree article

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ.

Mol Vis. 2003 May 30;9:210-6.PMID: 12789138 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene therapy for choroideremia: in vitro rescue mediated by recombinant adenovirus.

Anand V, Barral DC, Zeng Y, Brunsmann F, Maguire AM, Seabra MC, Bennett J.

Vision Res. 2003 Apr;43(8):919-26.PMID: 12668061 [PubMed - indexed for MEDLINE]Related articles

Efficient trans-splicing in the retina expands the utility of adeno-associated virus as a vector for gene therapy.

Reich SJ, Auricchio A, Hildinger M, Glover E, Maguire AM, Wilson JM, Bennett J.

Hum Gene Ther. 2003 Jan 1;14(1):37-44.PMID: 12573057 [PubMed - indexed for MEDLINE]Related articles

Traumatic retinal break from viscoelastic cannula during cataract surgery.

Prenner JL, Tolentino MJ, Maguire AM.

Arch Ophthalmol. 2003 Jan;121(1):128-9. No abstract available. PMID: 12523902 [PubMed - indexed for MEDLINE]Related articles

Variability in fluorescein angiography interpretation for photodynamic therapy in age-related macular degeneration.

Kaiser RS, Berger JW, Williams GA, Tolentino MJ, Maguire AM, Alexander J, Madjarov B, Margherio RM.

Retina. 2002 Dec;22(6):683-90.PMID: 12476092 [PubMed - indexed for MEDLINE]Related articles

Multifocal choroiditis in patients with familial juvenile systemic granulomatosis.

Latkany PA, Jabs DA, Smith JR, Rosenbaum JT, Tessler H, Schwab IR, Walton RC, Thorne JE, Maguire AM.

Am J Ophthalmol. 2002 Dec;134(6):897-904.PMID: 12470760 [PubMed - indexed for MEDLINE]Related articles

Phenotypic rescue after adeno-associated virus-mediated delivery of 4-sulfatase to the retinal pigment epithelium of feline mucopolysaccharidosis VI.

Ho TT, Maguire AM, Aguirre GD, Surace EM, Anand V, Zeng Y, Salvetti A, Hopwood JJ, Haskins ME, Bennett J.

J Gene Med. 2002 Nov-Dec;4(6):613-21.PMID: 12439853 [PubMed - indexed for MEDLINE]Related articles

Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents.

Auricchio A, Behling KC, Maguire AM, O'Connor EM, Bennett J, Wilson JM, Tolentino MJ.

Mol Ther. 2002 Oct;6(4):490-4.PMID: 12377190 [PubMed - indexed for MEDLINE]Related articles

Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs.

Ponder KP, Melniczek JR, Xu L, Weil MA, O'Malley TM, O'Donnell PA, Knox VW, Aguirre GD, Mazrier H, Ellinwood NM, Sleeper M, Maguire AM, Volk SW, Mango RL, Zweigle J, Wolfe JH, Haskins ME.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13102-7. Epub 2002 Sep 13.PMID: 12232044 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye.

Auricchio A, Rivera VM, Clackson T, O'Connor EE, Maguire AM, Tolentino MJ, Bennett J, Wilson JM.

Mol Ther. 2002 Aug;6(2):238-42.PMID: 12161190 [PubMed - indexed for MEDLINE]Related articles