PubMed

Ventromedial hypothalamic nitric oxide production is necessary for hypoglycemia detection and counter-regulation.

Fioramonti X, Marsollier N, Song Z, Fakira KA, Patel RM, Brown S, Duparc T, Pica-Mendez A, Sanders NM, Knauf C, Valet P, McCrimmon RJ, Beuve A, Magnan C, Routh VH.

Diabetes. 2009 Nov 23. [Epub ahead of print]PMID: 19934009 [PubMed - as supplied by publisher]Related articles

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents.

Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ.

J Clin Invest. 2009 Sep;119(9):2577-89. doi: 10.1172/JCI36714. Epub 2009 Aug 10.PMID: 19726875 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of maternal genotype and diet on offspring glucose and fatty acid-sensing ventromedial hypothalamic nucleus neurons.

Le Foll C, Irani BG, Magnan C, Dunn-Meynell A, Levin BE.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1351-7. Epub 2009 Aug 26.PMID: 19710389 [PubMed - in process]Related articles

Deregulation of hepatic insulin sensitivity induced by central lipid infusion in rats is mediated by nitric oxide.

Marsollier N, Kassis N, Mezghenna K, Soty M, Fioramonti X, Lacombe A, Joly A, Pillot B, Zitoun C, Vilar J, Mithieux G, Gross R, Lajoix AD, Routh V, Magnan C, Cruciani-Guglielmacci C.

PLoS One. 2009 Aug 14;4(8):e6649.PMID: 19680547 [PubMed - in process]Related articlesFree article

Enhanced hypothalamic glucose sensing in obesity: alteration of redox signaling.

Colombani AL, Carneiro L, Benani A, Galinier A, Jaillard T, Duparc T, Offer G, Lorsignol A, Magnan C, Casteilla L, Pénicaud L, Leloup C.

Diabetes. 2009 Oct;58(10):2189-97. Epub 2009 Jul 6.PMID: 19581415 [PubMed - indexed for MEDLINE]Related articles

SOLpro: accurate sequence-based prediction of protein solubility.

Magnan CN, Randall A, Baldi P.

Bioinformatics. 2009 Sep 1;25(17):2200-7. Epub 2009 Jun 23.PMID: 19549632 [PubMed - indexed for MEDLINE]Related articles

Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing.

Le Foll C, Irani BG, Magnan C, Dunn-Meynell AA, Levin BE.

Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R655-64. Epub 2009 Jun 17.PMID: 19535676 [PubMed - indexed for MEDLINE]Related articles

The central nervous system at the core of the regulation of energy homeostasis.

Luquet S, Magnan C.

Front Biosci (Schol Ed). 2009 Jun 1;1:448-65.PMID: 19482713 [PubMed - in process]Related articles

Intestinal gluconeogenesis: key signal of central control of energy and glucose homeostasis.

Mithieux G, Andreelli F, Magnan C.

Curr Opin Clin Nutr Metab Care. 2009 Jul;12(4):419-23. Review.PMID: 19474723 [PubMed - indexed for MEDLINE]Related articles

Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker.

Karaca M, Castel J, Tourrel-Cuzin C, Brun M, Géant A, Dubois M, Catesson S, Rodriguez M, Luquet S, Cattan P, Lockhart B, Lang J, Ktorza A, Magnan C, Kargar C.

PLoS One. 2009;4(5):e5555. Epub 2009 May 18.PMID: 19440374 [PubMed - indexed for MEDLINE]Related articlesFree article

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007. Epub 2009 Apr 13.PMID: 19363290 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative effects of Citrullus colocynthis, sunflower and olive oil-enriched diet in streptozotocin-induced diabetes in rats.

Sebbagh N, Cruciani-Guglielmacci C, Ouali F, Berthault MF, Rouch C, Sari DC, Magnan C.

Diabetes Metab. 2009 Jun;35(3):178-84. Epub 2009 Mar 4.PMID: 19264524 [PubMed - indexed for MEDLINE]Related articles

Functional pancreatic beta-cell mass: involvement in type 2 diabetes and therapeutic intervention.

Karaca M, Magnan C, Kargar C.

Diabetes Metab. 2009 Apr;35(2):77-84. Epub 2009 Feb 28. Review.PMID: 19251449 [PubMed - indexed for MEDLINE]Related articles

S26948, a new specific peroxisome proliferator activated receptor gamma modulator improved in vivo hepatic insulin sensitivity in 48 h lipid infused rats.

Sohn KA, Cruciani-Guglielmacci C, Kassis N, Clément L, Ouali F, Caüzac M, Lebègue N, Berthelot P, Caignard DH, Pégorier JP, Renard P, Dacquet C, Ktorza A, Magnan C; Consortium of the French Ministry of Research and Technology.

Eur J Pharmacol. 2009 Apr 17;608(1-3):104-11. Epub 2009 Feb 26.PMID: 19250932 [PubMed - indexed for MEDLINE]Related articles

Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice.

Migrenne S, Lacombe A, Lefèvre AL, Pruniaux MP, Guillot E, Galzin AM, Magnan C.

Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R929-35. Epub 2009 Feb 11.PMID: 19211723 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.

Leloup C, Tourrel-Cuzin C, Magnan C, Karaca M, Castel J, Carneiro L, Colombani AL, Ktorza A, Casteilla L, Pénicaud L.

Diabetes. 2009 Mar;58(3):673-81. Epub 2008 Dec 10.PMID: 19073765 [PubMed - indexed for MEDLINE]Related articlesFree article

The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathways.

Perilhou A, Tourrel-Cuzin C, Kharroubi I, Henique C, Fauveau V, Kitamura T, Magnan C, Postic C, Prip-Buus C, Vasseur-Cognet M.

Mol Cell Biol. 2008 Nov;28(21):6568-79. Epub 2008 Sep 2.PMID: 18765640 [PubMed - indexed for MEDLINE]Related articlesFree article

Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice.

Troy S, Soty M, Ribeiro L, Laval L, Migrenne S, Fioramonti X, Pillot B, Fauveau V, Aubert R, Viollet B, Foretz M, Leclerc J, Duchampt A, Zitoun C, Thorens B, Magnan C, Mithieux G, Andreelli F.

Cell Metab. 2008 Sep;8(3):201-11.PMID: 18762021 [PubMed - indexed for MEDLINE]Related articles

Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity.

Cabou C, Campistron G, Marsollier N, Leloup C, Cruciani-Guglielmacci C, Pénicaud L, Drucker DJ, Magnan C, Burcelin R.

Diabetes. 2008 Oct;57(10):2577-87. Epub 2008 Jul 15.PMID: 18633100 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress contributes to aging by enhancing pancreatic angiogenesis and insulin signaling.

Laurent G, Solari F, Mateescu B, Karaca M, Castel J, Bourachot B, Magnan C, Billaud M, Mechta-Grigoriou F.

Cell Metab. 2008 Feb;7(2):113-24.PMID: 18249171 [PubMed - indexed for MEDLINE]Related articles

mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes.

Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N, Leibowitz G.

Diabetes. 2008 Apr;57(4):945-57. Epub 2008 Jan 3.PMID: 18174523 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin internalizes GLUT2 in the enterocytes of healthy but not insulin-resistant mice.

Tobin V, Le Gall M, Fioramonti X, Stolarczyk E, Blazquez AG, Klein C, Prigent M, Serradas P, Cuif MH, Magnan C, Leturque A, Brot-Laroche E.

Diabetes. 2008 Mar;57(3):555-62. Epub 2007 Dec 5.PMID: 18057092 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid sensing and nervous control of energy homeostasis.

Migrenne S, Magnan C, Cruciani-Guglielmacci C.

Diabetes Metab. 2007 Jun;33(3):177-82. Epub 2007 May 1. Review.PMID: 17475532 [PubMed - indexed for MEDLINE]Related articlesFree article

Free fatty acids and insulin resistance.

Delarue J, Magnan C.

Curr Opin Clin Nutr Metab Care. 2007 Mar;10(2):142-8. Review.PMID: 17285001 [PubMed - indexed for MEDLINE]Related articles

[Fatty acid sensors and neurologic control of energetic homeostasis]

Cruciani-Guglielmacci C, Migrenne S, Clément L, Magnan C.

Journ Annu Diabetol Hotel Dieu. 2006:13-23. Review. French. No abstract available. PMID: 17051846 [PubMed - indexed for MEDLINE]Related articles

Importance of the gut-brain axis in the control of glucose homeostasis.

Migrenne S, Marsollier N, Cruciani-Guglielmacci C, Magnan C.

Curr Opin Pharmacol. 2006 Dec;6(6):592-7. Epub 2006 Sep 20. Review.PMID: 16990049 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing.

Leloup C, Magnan C, Benani A, Bonnet E, Alquier T, Offer G, Carriere A, Périquet A, Fernandez Y, Ktorza A, Casteilla L, Pénicaud L.

Diabetes. 2006 Jul;55(7):2084-90.PMID: 16804079 [PubMed - indexed for MEDLINE]Related articlesFree article

Body-esteem, body mass index, and risk for disordered eating among adolescents in synchronized swimming.

Ferrand C, Magnan C, Philippe RA.

Percept Mot Skills. 2005 Dec;101(3):877-84.PMID: 16491692 [PubMed - indexed for MEDLINE]Related articles

Psammomys obesus, a model for environment-gene interactions in type 2 diabetes.

Kaiser N, Nesher R, Donath MY, Fraenkel M, Behar V, Magnan C, Ktorza A, Cerasi E, Leibowitz G.

Diabetes. 2005 Dec;54 Suppl 2:S137-44. Review.PMID: 16306331 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels.

Wang R, Cruciani-Guglielmacci C, Migrenne S, Magnan C, Cotero VE, Routh VH.

J Neurophysiol. 2006 Mar;95(3):1491-8. Epub 2005 Nov 23.PMID: 16306178 [PubMed - indexed for MEDLINE]Related articlesFree article

Portal sensing of intestinal gluconeogenesis is a mechanistic link in the diminution of food intake induced by diet protein.

Mithieux G, Misery P, Magnan C, Pillot B, Gautier-Stein A, Bernard C, Rajas F, Zitoun C.

Cell Metab. 2005 Nov;2(5):321-9.PMID: 16271532 [PubMed - indexed for MEDLINE]Related articles

Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain.

Bienvenu G, Seurin D, Le Bouc Y, Even P, Babajko S, Magnan C.

Diabetologia. 2005 Jun;48(6):1189-97. Epub 2005 May 12.PMID: 15889232 [PubMed - indexed for MEDLINE]Related articles

F-DIO obesity-prone rat is insulin resistant before obesity onset.

Levin BE, Magnan C, Migrenne S, Chua SC Jr, Dunn-Meynell AA.

Am J Physiol Regul Integr Comp Physiol. 2005 Sep;289(3):R704-11. Epub 2005 May 5.PMID: 15879056 [PubMed - indexed for MEDLINE]Related articles

Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats.

Cruciani-Guglielmacci C, Hervalet A, Douared L, Sanders NM, Levin BE, Ktorza A, Magnan C.

Diabetologia. 2004 Nov;47(11):2032-8. Epub 2004 Nov 30.PMID: 15599702 [PubMed - indexed for MEDLINE]Related articles

Early changes in insulin secretion and action induced by high-fat diet are related to a decreased sympathetic tone.

Cruciani-Guglielmacci C, Vincent-Lamon M, Rouch C, Orosco M, Ktorza A, Magnan C.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E148-54. Epub 2004 Sep 7.PMID: 15353406 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrauterine hyperglycemia increases insulin binding sites but not glucose transporter expression in discrete brain areas in term rat fetuses.

Leloup C, Magnan C, Alquier T, Mistry S, Offer G, Arnaud E, Kassis N, Ktorza A, Pénicaud L.

Pediatr Res. 2004 Aug;56(2):263-7. Epub 2004 Jun 4.PMID: 15181191 [PubMed - indexed for MEDLINE]Related articles

Leptin receptor-deficient obese Zucker rats reduce their food intake in response to a systemic supply of calories from glucose.

Gilbert M, Magnan C, Turban S, André J, Guerre-Millo M.

Diabetes. 2003 Feb;52(2):277-82.PMID: 12540597 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracerebroventricular infusion of a triglyceride emulsion leads to both altered insulin secretion and hepatic glucose production in rats.

Clément L, Cruciani-Guglielmacci C, Magnan C, Vincent M, Douared L, Orosco M, Assimacopoulos-Jeannet F, Pénicaud L, Ktorza A.

Pflugers Arch. 2002 Dec;445(3):375-80. Epub 2002 Nov 1.PMID: 12466940 [PubMed - indexed for MEDLINE]Related articles

Pancreatic beta-cell alpha2A adrenoceptor and phospholipid changes in hyperlipidemic rats.

Clément L, Kim-Sohn KA, Magnan C, Kassis N, Adnot P, Kergoat M, Assimacopoulos-Jeannet F, Pénicaud L, Hsu F, Turk J, Ktorza A.

Lipids. 2002 May;37(5):501-6.PMID: 12056593 [PubMed - indexed for MEDLINE]Related articles

Glucose-induced insulin hypersecretion in lipid-infused healthy subjects is associated with a decrease in plasma norepinephrine concentration and urinary excretion.

Magnan C, Cruciani C, Clément L, Adnot P, Vincent M, Kergoat M, Girard A, Elghozi JL, Velho G, Beressi N, Bresson JL, Ktorza A.

J Clin Endocrinol Metab. 2001 Oct;86(10):4901-7.PMID: 11600560 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered Glut4 mRNA levels in specific brain areas of hyperglycemic-hyperinsulinemic rats.

Alquier T, Leloup C, Arnaud E, Magnan C, Pénicaud L.

Neurosci Lett. 2001 Aug 3;308(2):75-8.PMID: 11457563 [PubMed - indexed for MEDLINE]Related articles

Microparticles of soy lecithin formed by supercritical processes.

Badens E, Magnan C, Charbit G.

Biotechnol Bioeng. 2001 Jan 20;72(2):194-204.PMID: 11114657 [PubMed - indexed for MEDLINE]Related articles

Neoral dose monitoring with cyclosporine 2-hour postdose levels in heart transplant patients receiving anti-thymocyte globulin induction.

Cantarovich M, Quantz M, Elstein E, Ergina P, Magnan C, de Varennes B.

Transplant Proc. 2000 Mar;32(2):446-8. No abstract available. PMID: 10715475 [PubMed - indexed for MEDLINE]Related articles

Glucose regulates proinsulin and prosomatostatin but not proglucagon messenger ribonucleic acid levels in rat pancreatic islets.

Dumonteil E, Magnan C, Ritz-Laser B, Ktorza A, Meda P, Philippe J.

Endocrinology. 2000 Jan;141(1):174-80.PMID: 10614637 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exposure to high glucose concentrations increases proglucagon messenger ribonucleic acid levels and glucagon release from InR1G9 cells.

Dumonteil E, Ritz-Laser B, Magnan C, Grigorescu I, Ktorza A, Philippe J.

Endocrinology. 1999 Oct;140(10):4644-50.PMID: 10499521 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate.

Ritz-Laser B, Meda P, Constant I, Klages N, Charollais A, Morales A, Magnan C, Ktorza A, Philippe J.

Endocrinology. 1999 Sep;140(9):4005-14.PMID: 10465270 [PubMed - indexed for MEDLINE]Related articlesFree article

Optimal timing for surveillance endomyocardial biopsies in heart transplant patients receiving antithymocyte globulin induction.

Cantarovich M, de Gruchy S, Forbes C, Marpole D, Elstein E, Magnan C, de Varennes B.

Transplant Proc. 1999 Feb-Mar;31(1-2):79. No abstract available. PMID: 10083015 [PubMed - indexed for MEDLINE]Related articles

Lipid infusion lowers sympathetic nervous activity and leads to increased beta-cell responsiveness to glucose.

Magnan C, Collins S, Berthault MF, Kassis N, Vincent M, Gilbert M, Pénicaud L, Ktorza A, Assimacopoulos-Jeannet F.

J Clin Invest. 1999 Feb;103(3):413-9.PMID: 9927503 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin, but not glucose lowering corrects the hyperglucagonemia and increased proglucagon messenger ribonucleic acid levels observed in insulinopenic diabetes.

Dumonteil E, Magnan C, Ritz-Laser B, Meda P, Dussoix P, Gilbert M, Ktorza A, Philippe J.

Endocrinology. 1998 Nov;139(11):4540-6.PMID: 9794463 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered activity of the autonomous nervous system as a determinant of the impaired beta-cell secretory response after protein-energy restriction in the rat.

Leon-Quinto T, Magnan C, Portha B.

Endocrinology. 1998 Aug;139(8):3382-9.PMID: 9681486 [PubMed - indexed for MEDLINE]Related articlesFree article