PubMed

Adding liraglutide to oral antidiabetic drug therapy: onset of treatment effects over time.

Gallwitz B, Vaag A, Falahati A, Madsbad S.

Int J Clin Pract. 2009 Nov 19. [Epub ahead of print]PMID: 19925617 [PubMed - as supplied by publisher]Related articles

Treatment of Type 1 Diabetic Patients with Glucagon-Like Peptide-1 (GLP-1) and GLP-1R Agonists.

Kielgast U, Holst JJ, Madsbad S.

Curr Diabetes Rev. 2009 Nov;5(4):266-275.PMID: 19925391 [PubMed - as supplied by publisher]Related articles

Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report.

Dirksen C, Hansen DL, Madsbad S, Hvolris LE, Naver LS, Holst JJ, Worm D.

Diabetes Care. 2009 Nov 16. [Epub ahead of print]PMID: 19918005 [PubMed - as supplied by publisher]Related articles

Incretin-based therapies: viewpoints on the way to consensus.

Nauck MA, Vilsbøll T, Gallwitz B, Garber A, Madsbad S.

Diabetes Care. 2009 Nov;32 Suppl 2:S223-31. No abstract available. PMID: 19875556 [PubMed - in process]Related articles

Preserved Inhibitory Potency of GLP-1 on Glucagon Secretion in Type 2 Diabetes Mellitus.

Hare KJ, Knop FK, Asmar M, Madsbad S, Deacon CF, Holst JJ, Vilsbøll T.

J Clin Endocrinol Metab. 2009 Oct 16. [Epub ahead of print]PMID: 19837930 [PubMed - as supplied by publisher]Related articles

[The effect of tesofensine on body weight and body composition in obese subjects--secondary publication]

Nielsen AL, Larsen TM, Madsbad S, Breum L, Jensen TJ, Kroustrup JP, Astrup A.

Ugeskr Laeger. 2009 Oct 5;171(41):2974-7. Danish. PMID: 19824222 [PubMed - indexed for MEDLINE]Related articles

Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)--preclinical and clinical results.

Madsbad S.

Best Pract Res Clin Endocrinol Metab. 2009 Aug;23(4):463-77.PMID: 19748064 [PubMed - in process]Related articles

Expression of 11beta-hydroxysteroid dehydrogenase 1 and 2 in subcutaneous adipose tissue of lean and obese women with and without polycystic ovary syndrome.

Svendsen PF, Madsbad S, Nilas L, Paulsen SK, Pedersen SB.

Int J Obes (Lond). 2009 Nov;33(11):1249-56. Epub 2009 Aug 25.PMID: 19704410 [PubMed - in process]Related articles

Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention.

Haugaard SB, Vaag A, Mu H, Madsbad S.

Lipids Health Dis. 2009 Aug 13;8:34.PMID: 19678948 [PubMed - in process]Related articlesFree article

The insulin-resistant phenotype of polycystic ovary syndrome.

Svendsen PF, Madsbad S, Nilas L.

Fertil Steril. 2009 Jul 4. [Epub ahead of print]PMID: 19580964 [PubMed - as supplied by publisher]Related articles

The prevalence of metabolic syndrome in Danish patients with HIV infection: the effect of antiretroviral therapy.

Hansen BR, Petersen J, Haugaard SB, Madsbad S, Obel N, Suzuki Y, Andersen O.

HIV Med. 2009 Jul;10(6):378-87. Epub 2009 Mar 26.PMID: 19490178 [PubMed - in process]Related articles

Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss.

Rabøl R, Svendsen PF, Skovbro M, Boushel R, Haugaard SB, Schjerling P, Schrauwen P, Hesselink MK, Nilas L, Madsbad S, Dela F.

Metabolism. 2009 Aug;58(8):1145-52. Epub 2009 Jun 18.PMID: 19454354 [PubMed - indexed for MEDLINE]Related articles

Intramyocellular triglyceride content in man, influence of sex, obesity and glycaemic control.

Haugaard SB, Mu H, Vaag A, Madsbad S.

Eur J Endocrinol. 2009 Jul;161(1):57-64. Epub 2009 May 5.PMID: 19417077 [PubMed - indexed for MEDLINE]Related articles

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.

Sparsø T, Grarup N, Andreasen C, Albrechtsen A, Holmkvist J, Andersen G, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O.

Diabetologia. 2009 Jul;52(7):1308-14. Epub 2009 Apr 29.PMID: 19404609 [PubMed - indexed for MEDLINE]Related articles

Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin.

Svendsen PF, Nilas L, Madsbad S, Holst JJ.

Metabolism. 2009 May;58(5):586-93.PMID: 19375579 [PubMed - indexed for MEDLINE]Related articles

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.

Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P.

Diabetes. 2009 Jun;58(6):1450-6. Epub 2009 Mar 26.PMID: 19324940 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin receptor agonist (TZP-101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis.

Ejskjaer N, Vestergaard ET, Hellström PM, Gormsen LC, Madsbad S, Madsen JL, Jensen TA, Pezzullo JC, Christiansen JS, Shaughnessy L, Kosutic G.

Aliment Pharmacol Ther. 2009 Jun 1;29(11):1179-87. Epub 2009 Feb 27.PMID: 19298585 [PubMed - in process]Related articles

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsbøll T, Hansen T, Madsbad S, Holst JJ, Vølund A, Poulsen P, Groop L, Pedersen O, Vaag AA.

Diabetologia. 2009 Jul;52(7):1298-307. Epub 2009 Mar 14.PMID: 19288077 [PubMed - indexed for MEDLINE]Related articles

[Surgical treatment of diabetes mellitus type 2]

Olesen SC, Hansen DL, Almdal T, Bendtsen F, Nordgaard I, Hvolris LE, Holst JJ, Naver L, Madsbad S.

Ugeskr Laeger. 2009 Feb 16;171(8):615-7. Danish. PMID: 19284908 [PubMed - indexed for MEDLINE]Related articles

Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes.

Rabøl R, Højberg PM, Almdal T, Boushel R, Haugaard SB, Madsbad S, Dela F.

Diabetes Obes Metab. 2009 Apr;11(4):355-60.PMID: 19267714 [PubMed - in process]Related articles

Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial.

Lundby Christensen L, Almdal T, Boesgaard T, Breum L, Dunn E, Gade-Rasmussen B, Gluud C, Hedetoft C, Jarloev A, Jensen T, Krarup T, Johansen LB, Lund SS, Madsbad S, Mathiesen E, Moelvig J, Nielsen F, Perrild H, Pedersen O, Roeder M, Sneppen SB, Snorgaard O, Tarnow L, Thorsteinsson B, Vaag A, Vestergaard H, Wetterslev J, Wiinberg N; CIMT Trial Group.

Diabetes Obes Metab. 2009 Apr;11(4):315-22.PMID: 19267709 [PubMed - in process]Related articles

Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes.

Courrèges JP, Vilsbøll T, Zdravkovic M, Le-Thi T, Krarup T, Schmitz O, Verhoeven R, Bugáñová I, Madsbad S.

Diabet Med. 2008 Sep;25(9):1129-31. No abstract available. PMID: 19183322 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of hyperglycemia on mitochondrial respiration in type 2 diabetes.

Rabøl R, Højberg PM, Almdal T, Boushel R, Haugaard SB, Madsbad S, Dela F.

J Clin Endocrinol Metab. 2009 Apr;94(4):1372-8. Epub 2009 Jan 13.PMID: 19141588 [PubMed - indexed for MEDLINE]Related articles

The proposed terminology 'A1c-derived average glucose' is inherently imprecise and should not be adopted. Reply to Bloomgarden ZT, Inzucchi SE, Karnieli E, et al.

Haugaard SB, Madsbad S, Mølvig J.

Diabetologia. 2009 Mar;52(3):547-9. Epub 2008 Dec 9. No abstract available. PMID: 19066843 [PubMed - indexed for MEDLINE]Related articles

KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.

Aaboe K, Knop FK, Vilsboll T, Vølund A, Simonsen U, Deacon CF, Madsbad S, Holst JJ, Krarup T.

J Clin Endocrinol Metab. 2009 Feb;94(2):603-8. Epub 2008 Dec 2.PMID: 19050053 [PubMed - indexed for MEDLINE]Related articles

Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes.

Højberg PV, Vilsbøll T, Zander M, Knop FK, Krarup T, Vølund A, Holst JJ, Madsbad S.

Diabet Med. 2008 Nov;25(11):1268-75.PMID: 19046215 [PubMed - indexed for MEDLINE]Related articles

Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.

Højberg PV, Vilsbøll T, Rabøl R, Knop FK, Bache M, Krarup T, Holst JJ, Madsbad S.

Diabetologia. 2009 Feb;52(2):199-207. Epub 2008 Nov 27.PMID: 19037628 [PubMed - indexed for MEDLINE]Related articles

Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight.

Jensen CB, Martin-Gronert MS, Storgaard H, Madsbad S, Vaag A, Ozanne SE.

PLoS One. 2008;3(11):e3738. Epub 2008 Nov 17.PMID: 19011679 [PubMed - indexed for MEDLINE]Related articlesFree article

[Glycemic control and cardiovascular diseases in type 2 diabetes]

Madsbad S.

Ugeskr Laeger. 2008 Nov 3;170(45):3634. Danish. No abstract available. PMID: 18986612 [PubMed - indexed for MEDLINE]Related articles

Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial.

Astrup A, Madsbad S, Breum L, Jensen TJ, Kroustrup JP, Larsen TM.

Lancet. 2008 Nov 29;372(9653):1906-13. Epub 2008 Oct 22.PMID: 18950853 [PubMed - indexed for MEDLINE]Related articles

Treatment of type 2 diabetes with incretin-based therapies.

Madsbad S.

Lancet. 2009 Feb 7;373(9662):438-9. Epub 2008 Sep 24. No abstract available. PMID: 18819704 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein, insulin resistance and risk of cardiovascular disease: a population-based study.

Jeppesen J, Hansen TW, Olsen MH, Rasmussen S, Ibsen H, Torp-Pedersen C, Hildebrandt PR, Madsbad S.

Eur J Cardiovasc Prev Rehabil. 2008 Oct;15(5):594-8.PMID: 18753952 [PubMed - indexed for MEDLINE]Related articles

Sex and muscle structural lipids in obese subjects - an impact on insulin action?

Haugaard SB, Vaag A, Høy CE, Madsbad S.

Eur J Clin Invest. 2008 Jul;38(7):494-501.PMID: 18578691 [PubMed - indexed for MEDLINE]Related articles

[New biological drugs for the treatment of chronic inflammatory diseases]

Skov L, Hegedüs L, Madsbad S, Bendtzen K.

Ugeskr Laeger. 2008 Jun 9;170(24):2162. Danish. No abstract available. PMID: 18572482 [PubMed - indexed for MEDLINE]Related articles

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.

Sparsø T, Andersen G, Albrechtsen A, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Wasson J, Permutt MA, Glaser B, Madsbad S, Pedersen O, Hansen T.

Diabetologia. 2008 Sep;51(9):1646-52. Epub 2008 Jun 21.PMID: 18568334 [PubMed - indexed for MEDLINE]Related articles

Obesity, body composition and metabolic disturbances in polycystic ovary syndrome.

Svendsen PF, Nilas L, Nørgaard K, Jensen JE, Madsbad S.

Hum Reprod. 2008 Sep;23(9):2113-21. Epub 2008 Jun 12.PMID: 18556679 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials.

Madsbad S, Krarup T, Deacon CF, Holst JJ.

Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):491-9. Review.PMID: 18542012 [PubMed - indexed for MEDLINE]Related articles

GLP-1: physiological effects and potential therapeutic applications.

Aaboe K, Krarup T, Madsbad S, Holst JJ.

Diabetes Obes Metab. 2008 Nov;10(11):994-1003. Epub 2008 Apr 22. Review.PMID: 18435775 [PubMed - indexed for MEDLINE]Related articles

Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide.

Horowitz M, Vilsbøll T, Zdravkovic M, Hammer M, Madsbad S.

Diabetes Obes Metab. 2008 Jul;10(7):593-6. Epub 2008 Apr 22. No abstract available. PMID: 18435773 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1, glucose homeostasis and diabetes.

Holst JJ, Deacon CF, Vilsbøll T, Krarup T, Madsbad S.

Trends Mol Med. 2008 Apr;14(4):161-8. Epub 2008 Mar 18. Review.PMID: 18353723 [PubMed - indexed for MEDLINE]Related articles

Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes.

Højberg PV, Zander M, Vilsbøll T, Knop FK, Krarup T, Vølund A, Holst JJ, Madsbad S.

Diabetologia. 2008 Apr;51(4):632-40. Epub 2008 Feb 22.PMID: 18292985 [PubMed - indexed for MEDLINE]Related articles

Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus.

Vilsbøll T, Brock B, Perrild H, Levin K, Lervang HH, Kølendorf K, Krarup T, Schmitz O, Zdravkovic M, Le-Thi T, Madsbad S.

Diabet Med. 2008 Feb;25(2):152-6. Epub 2008 Jan 14.PMID: 18201212 [PubMed - indexed for MEDLINE]Related articles

[Treatment of patients with type 2 diabetes mellitus with pioglitazone. A survey of a Cochrane review]

Madsbad S.

Ugeskr Laeger. 2007 Nov 19;169(47):4054-7. Review. Danish. No abstract available. PMID: 18078659 [PubMed - indexed for MEDLINE]Related articles

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.

Sparsø T, Andersen G, Nielsen T, Burgdorf KS, Gjesing AP, Nielsen AL, Albrechtsen A, Rasmussen SS, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O.

Diabetologia. 2008 Jan;51(1):70-5. Epub 2007 Nov 16. Erratum in: Diabetologia. 2008 Feb;51(2):383. PMID: 18008060 [PubMed - indexed for MEDLINE]Related articles

The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

Knop FK, Vilsbøll T, Højberg PV, Larsen S, Madsbad S, Holst JJ, Krarup T.

Regul Pept. 2007 Dec 4;144(1-3):123-30. Epub 2007 Jul 13.PMID: 17692937 [PubMed - indexed for MEDLINE]Related articles

Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites.

Sparsø T, Hussain MS, Borch-Johnsen K, Jørgensen T, Madsbad S, Hansen T, Pedersen O, Andersen G.

Mol Genet Metab. 2007 Nov;92(3):278-82. Epub 2007 Aug 2.PMID: 17681849 [PubMed - indexed for MEDLINE]Related articles

Impaired proinsulin secretion before and during oral glucose stimulation in HIV-infected patients who display fat redistribution.

Haugaard SB, Andersen O, Halsall I, Iversen J, Hales CN, Madsbad S.

Metabolism. 2007 Jul;56(7):939-46.PMID: 17570256 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease: a population-based study.

Jeppesen J, Hansen TW, Rasmussen S, Ibsen H, Torp-Pedersen C, Madsbad S.

J Am Coll Cardiol. 2007 May 29;49(21):2112-9. Epub 2007 May 17.PMID: 17531661 [PubMed - indexed for MEDLINE]Related articles

Circulating sex hormones and gene expression of subcutaneous adipose tissue oestrogen and alpha-adrenergic receptors in HIV-lipodystrophy: implications for fat distribution.

Andersen O, Pedersen SB, Svenstrup B, Hansen BR, Paulsen SK, Rathje GS, Richelsen B, Nielsen JO, Madsbad S, Iversen J, Haugaard SB.

Clin Endocrinol (Oxf). 2007 Aug;67(2):250-8. Epub 2007 May 24.PMID: 17524033 [PubMed - indexed for MEDLINE]Related articles

Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?

Knop FK, Vilsbøll T, Højberg PV, Larsen S, Madsbad S, Vølund A, Holst JJ, Krarup T.

Diabetes. 2007 Aug;56(8):1951-9. Epub 2007 May 18.PMID: 17513701 [PubMed - indexed for MEDLINE]Related articlesFree article