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    Results: 1 to 50 of 57

    1.

    Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.

    Carr EJ, Niederer HA, Williams J, Harper L, Watts RA, Lyons PA, Smith KG.

    BMC Med Genet. 2009 Dec 1;10(1):121. [Epub ahead of print]PMID: 19951419 [PubMed - as supplied by publisher]Related articlesFree article

    2.

    The Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ Regulatory T-cells.

    Yamanouchi J, Puertas MC, Verdaguer J, Lyons PA, Rainbow DB, Chamberlain G, Hunter KM, Peterson LB, Wicker LS, Santamaria P.

    Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833887 [PubMed - as supplied by publisher]Related articles

    3.

    Novel expression signatures identified by transcriptional analysis of separated leukocyte subsets in SLE and vasculitis.

    Lyons PA, McKinney EF, Rayner TF, Hatton A, Woffendin HB, Koukoulaki M, Freeman TC, Jayne DR, Chaudhry AN, Smith KG.

    Ann Rheum Dis. 2009 Oct 8. [Epub ahead of print]PMID: 19815495 [PubMed - as supplied by publisher]Related articlesFree article

    4.

    Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

    Carr EJ, Clatworthy MR, Lowe CE, Todd JA, Wong A, Vyse TJ, Kamesh L, Watts RA, Lyons PA, Smith KG.

    BMC Med Genet. 2009 Mar 5;10:22.PMID: 19265545 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Complement abnormalities in acquired lipodystrophy revisited.

    Savage DB, Semple RK, Clatworthy MR, Lyons PA, Morgan BP, Cochran EK, Gorden P, Raymond-Barker P, Murgatroyd PR, Adams C, Scobie I, Mufti GJ, Alexander GJ, Thiru S, Murano I, Cinti S, Chaudhry AN, Smith KG, O'Rahilly S.

    J Clin Endocrinol Metab. 2009 Jan;94(1):10-6. Epub 2008 Oct 14.PMID: 18854390 [PubMed - indexed for MEDLINE]Related articles

    6.

    Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake.

    Willcocks LC, Lyons PA, Clatworthy MR, Robinson JI, Yang W, Newland SA, Plagnol V, McGovern NN, Condliffe AM, Chilvers ER, Adu D, Jolly EC, Watts R, Lau YL, Morgan AW, Nash G, Smith KG.

    J Exp Med. 2008 Jul 7;205(7):1573-82. Epub 2008 Jun 16.PMID: 18559452 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb.

    Brownlie RJ, Lawlor KE, Niederer HA, Cutler AJ, Xiang Z, Clatworthy MR, Floto RA, Greaves DR, Lyons PA, Smith KG.

    J Exp Med. 2008 Apr 14;205(4):883-95. Epub 2008 Mar 24.PMID: 18362174 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    The nervous spleen: The nervous spleen.

    Clatworthy MR, Lyons PA, Smith KG.

    Immunol Cell Biol. 2008 Jan;86(1):1-2. No abstract available. PMID: 18172440 [PubMed - indexed for MEDLINE]Related articles

    9.

    Control of Rta expression critically determines transcription of viral and cellular genes following gammaherpesvirus infection.

    Hair JR, Lyons PA, Smith KG, Efstathiou S.

    J Gen Virol. 2007 Jun;88(Pt 6):1689-97.PMID: 17485528 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Microarray analysis of human leucocyte subsets: the advantages of positive selection and rapid purification.

    Lyons PA, Koukoulaki M, Hatton A, Doggett K, Woffendin HB, Chaudhry AN, Smith KG.

    BMC Genomics. 2007 Mar 5;8:64.PMID: 17338817 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro.

    Newland SA, Macaulay IC, Floto AR, de Vet EC, Ouwehand WH, Watkins NA, Lyons PA, Campbell DR.

    Blood. 2007 Jun 1;109(11):4806-9. Epub 2007 Feb 20.PMID: 17311996 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.

    Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS, Santamaria P.

    Nat Genet. 2007 Mar;39(3):329-37. Epub 2007 Feb 4.PMID: 17277778 [PubMed - indexed for MEDLINE]Related articles

    13.

    Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes.

    Morris GA, Lowe CE, Cooper JD, Payne F, Vella A, Godfrey L, Hulme JS, Walker NM, Healy BC, Lam AC, Lyons PA, Todd JA.

    BMC Genet. 2006 Feb 22;7:12.PMID: 16504056 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.

    Wicker LS, Moule CL, Fraser H, Penha-Goncalves C, Rainbow D, Garner VE, Chamberlain G, Hunter K, Howlett S, Clark J, Gonzalez-Munoz A, Cumiskey AM, Tiffen P, Howson J, Healy B, Smink LJ, Kingsnorth A, Lyons PA, Gregory S, Rogers J, Todd JA, Peterson LB.

    Novartis Found Symp. 2005;267:57-65; discussion 65-75.PMID: 15999801 [PubMed - indexed for MEDLINE]Related articles

    15.

    Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the proteins.

    Freilich S, Massingham T, Bhattacharyya S, Ponsting H, Lyons PA, Freeman TC, Thornton JM.

    Genome Biol. 2005;6(7):R56. Epub 2005 Jun 29.PMID: 15998445 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The cell surface receptor G6b, a member of the immunoglobulin superfamily, binds heparin.

    de Vet EC, Newland SA, Lyons PA, Aguado B, Campbell RD.

    FEBS Lett. 2005 Apr 25;579(11):2355-8.PMID: 15848171 [PubMed - indexed for MEDLINE]Related articles

    17.

    The murine cytomegalovirus M73.5 gene, a member of a 3' co-terminal alternatively spliced gene family, encodes the gp24 virion glycoprotein.

    Scalzo AA, Dallas PB, Forbes CA, Mikosza AS, Fleming P, Lathbury LJ, Lyons PA, Laferté S, Craggs MM, Loh LC.

    Virology. 2004 Nov 24;329(2):234-50.PMID: 15518804 [PubMed - indexed for MEDLINE]Related articles

    18.

    Genetic control of autoimmunity: protection from diabetes, but spontaneous autoimmune biliary disease in a nonobese diabetic congenic strain.

    Koarada S, Wu Y, Fertig N, Sass DA, Nalesnik M, Todd JA, Lyons PA, Fenyk-Melody J, Rainbow DB, Wicker LS, Peterson LB, Ridgway WM.

    J Immunol. 2004 Aug 15;173(4):2315-23.PMID: 15294944 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.

    Wicker LS, Chamberlain G, Hunter K, Rainbow D, Howlett S, Tiffen P, Clark J, Gonzalez-Munoz A, Cumiskey AM, Rosa RL, Howson JM, Smink LJ, Kingsnorth A, Lyons PA, Gregory S, Rogers J, Todd JA, Peterson LB.

    J Immunol. 2004 Jul 1;173(1):164-73.PMID: 15210771 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Global amplification of mRNA by template-switching PCR: linearity and application to microarray analysis.

    Petalidis L, Bhattacharyya S, Morris GA, Collins VP, Freeman TC, Lyons PA.

    Nucleic Acids Res. 2003 Nov 15;31(22):e142.PMID: 14602935 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling.

    Nikaido I, Saito C, Mizuno Y, Meguro M, Bono H, Kadomura M, Kono T, Morris GA, Lyons PA, Oshimura M, Hayashizaki Y, Okazaki Y; RIKEN GER Group; GSL Members.

    Genome Res. 2003 Jun;13(6B):1402-9.PMID: 12819139 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Continued discovery of transcriptional units expressed in cells of the mouse mononuclear phagocyte lineage.

    Wells CA, Ravasi T, Sultana R, Yagi K, Carninci P, Bono H, Faulkner G, Okazaki Y, Quackenbush J, Hume DA, Lyons PA; RIKEN GER Group; GSL Members.

    Genome Res. 2003 Jun;13(6B):1360-5.PMID: 12819134 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.

    Penha-Gonçalves C, Moule C, Smink LJ, Howson J, Gregory S, Rogers J, Lyons PA, Suttie JJ, Lord CJ, Peterson LB, Todd JA, Wicker LS.

    Diabetes. 2003 Jun;52(6):1551-6.PMID: 12765969 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    The derivation of highly germline-competent embryonic stem cells containing NOD-derived genome.

    Brook FA, Evans EP, Lord CJ, Lyons PA, Rainbow DB, Howlett SK, Wicker LS, Todd JA, Gardner RL.

    Diabetes. 2003 Jan;52(1):205-8.PMID: 12502514 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

    Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schönbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y; FANTOM Consortium; RIKEN Genome Exploration Research Group Phase I & II Team.

    Nature. 2002 Dec 5;420(6915):563-73.PMID: 12466851 [PubMed - indexed for MEDLINE]Related articles

    26.

    Gene-expression profiling and the genetic dissection of complex disease.

    Lyons PA.

    Curr Opin Immunol. 2002 Oct;14(5):627-30. Review.PMID: 12183164 [PubMed - indexed for MEDLINE]Related articles

    27.

    Combining mouse congenic strains and microarray gene expression analyses to study a complex trait: the NOD model of type 1 diabetes.

    Eaves IA, Wicker LS, Ghandour G, Lyons PA, Peterson LB, Todd JA, Glynne RJ.

    Genome Res. 2002 Feb;12(2):232-43.PMID: 11827943 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Localising quantitative trait loci in the NOD mouse model of type 1 diabetes.

    Lyons PA, Wicker LS.

    Curr Dir Autoimmun. 1999;1:208-25. Review. No abstract available. PMID: 11791443 [PubMed - indexed for MEDLINE]Related articles

    29.

    Mapping by genetic interaction: high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse.

    Lyons PA, Armitage N, Lord CJ, Phillips MS, Todd JA, Peterson LB, Wicker LS.

    Diabetes. 2001 Nov;50(11):2633-7.PMID: 11679445 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    Construction of microsatellite-based, high-resolution genetic maps in the mouse.

    Lyons PA.

    Methods Mol Biol. 2001;175:1-9. Review. No abstract available. PMID: 11462828 [PubMed - indexed for MEDLINE]Related articles

    31.

    Statistical modeling of interlocus interactions in a complex disease: rejection of the multiplicative model of epistasis in type 1 diabetes.

    Cordell HJ, Todd JA, Hill NJ, Lord CJ, Lyons PA, Peterson LB, Wicker LS, Clayton DG.

    Genetics. 2001 May;158(1):357-67.PMID: 11333244 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    The murine type 1 diabetes loci, Idd1, Idd3, Idd5, Idd9, and Idd17/10/18, do not control thymic CD4-CD8-/TCRalphabeta+ deficiency in the nonobese diabetic mouse.

    Lord CJ, Howlett S, Lyons PA, Peterson LB, Wicker LS, Todd JA.

    Mamm Genome. 2001 Feb;12(2):175-6. No abstract available. PMID: 11210190 [PubMed - indexed for MEDLINE]Related articles

    33.

    NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.

    Hill NJ, Lyons PA, Armitage N, Todd JA, Wicker LS, Peterson LB.

    Diabetes. 2000 Oct;49(10):1744-7.PMID: 11016460 [PubMed - indexed for MEDLINE]Related articlesFree article

    34.

    Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9.2.

    Siegmund T, Armitage N, Wicker LS, Peterson LB, Todd JA, Lyons PA.

    Diabetes. 2000 Sep;49(9):1612-6.PMID: 10969850 [PubMed - indexed for MEDLINE]Related articlesFree article

    35.

    The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137.

    Lyons PA, Hancock WW, Denny P, Lord CJ, Hill NJ, Armitage N, Siegmund T, Todd JA, Phillips MS, Hess JF, Chen SL, Fischer PA, Peterson LB, Wicker LS.

    Immunity. 2000 Jul;13(1):107-15.PMID: 10933399 [PubMed - indexed for MEDLINE]Related articles

    36.

    Differential glycosylation of interleukin 2, the molecular basis for the NOD Idd3 type 1 diabetes gene?

    Podolin PL, Wilusz MB, Cubbon RM, Pajvani U, Lord CJ, Todd JA, Peterson LB, Wicker LS, Lyons PA.

    Cytokine. 2000 May;12(5):477-82.PMID: 10857762 [PubMed - indexed for MEDLINE]Related articles

    37.

    Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping.

    Lyons PA, Armitage N, Argentina F, Denny P, Hill NJ, Lord CJ, Wilusz MB, Peterson LB, Wicker LS, Todd JA.

    Genome Res. 2000 Apr;10(4):446-53.PMID: 10779485 [PubMed - indexed for MEDLINE]Related articlesFree article

    38.

    Mouse chromosome 3.

    Lyons PA, Wakeland EK.

    Mamm Genome. 1999 Oct;10(10):942.PMID: 10501945 [PubMed - indexed for MEDLINE]Related articles

    39.

    Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse chromosome 3.

    Podolin PL, Denny P, Armitage N, Lord CJ, Hill NJ, Levy ER, Peterson LB, Todd JA, Wicker LS, Lyons PA.

    Mamm Genome. 1998 Apr;9(4):283-6.PMID: 9530623 [PubMed - indexed for MEDLINE]Related articles

    40.

    Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

    Podolin PL, Denny P, Lord CJ, Hill NJ, Todd JA, Peterson LB, Wicker LS, Lyons PA.

    J Immunol. 1997 Aug 15;159(4):1835-43.PMID: 9257847 [PubMed - indexed for MEDLINE]Related articles

    41.

    A 2-Mb YAC contig and physical map of the natural killer gene complex on mouse chromosome 6.

    Brown MG, Fulmek S, Matsumoto K, Cho R, Lyons PA, Levy ER, Scalzo AA, Yokoyama WM.

    Genomics. 1997 May 15;42(1):16-25.PMID: 9177771 [PubMed - indexed for MEDLINE]Related articles

    42.

    Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene.

    Denny P, Lord CJ, Hill NJ, Goy JV, Levy ER, Podolin PL, Peterson LB, Wicker LS, Todd JA, Lyons PA.

    Diabetes. 1997 Apr;46(4):695-700.PMID: 9075813 [PubMed - indexed for MEDLINE]Related articles

    43.

    Effect of natural sequence variation at the H-2Ld-restricted CD8+ T cell epitope of the murine cytomegalovirus ie1-encoded pp89 on T cell recognition.

    Lyons PA, Allan JE, Carrello C, Shellam GR, Scalzo AA.

    J Gen Virol. 1996 Oct;77 ( Pt 10):2615-23.PMID: 8887498 [PubMed - indexed for MEDLINE]Related articlesFree article

    44.

    Assessment of antigenicity and genetic variation of glycoprotein B of murine cytomegalovirus.

    Xu J, Lyons PA, Carter MD, Booth TW, Davis-Poynter NJ, Shellam GR, Scalzo AA.

    J Gen Virol. 1996 Jan;77 ( Pt 1):49-59.PMID: 8558128 [PubMed - indexed for MEDLINE]Related articlesFree article

    45.

    Reducing surgical supply expenses: one hospital's experience.

    Lyons PA.

    Aspens Advis Nurse Exec. 1995 Dec;11(3):8, 7. No abstract available. PMID: 8695306 [PubMed - indexed for MEDLINE]Related articles

    46.

    DNA sequence and transcriptional analysis of the glycoprotein M gene of murine cytomegalovirus.

    Scalzo AA, Forbes CA, Davis-Poynter NJ, Farrell HE, Lyons PA.

    J Gen Virol. 1995 Nov;76 ( Pt 11):2895-901.PMID: 7595401 [PubMed - indexed for MEDLINE]Related articlesFree article

    47.

    Genetic mapping of Cmv1 in the region of mouse chromosome 6 encoding the NK gene complex-associated loci Ly49 and musNKR-P1.

    Scalzo AA, Lyons PA, Fitzgerald NA, Forbes CA, Yokoyama WM, Shellam GR.

    Genomics. 1995 Jun 10;27(3):435-41.PMID: 7558024 [PubMed - indexed for MEDLINE]Related articles

    48.

    The BALB.B6-Cmv1r mouse: a strain congenic for Cmv1 and the NK gene complex.

    Scalzo AA, Lyons PA, Fitzgerald NA, Forbes CA, Shellam GR.

    Immunogenetics. 1995;41(2-3):148-51. No abstract available. PMID: 7806288 [PubMed - indexed for MEDLINE]Related articles

    49.

    Identification, sequencing and expression of the glycoprotein L gene of murine cytomegalovirus.

    Xu J, Scalzo AA, Lyons PA, Farrell HE, Rawlinson WD, Shellam GR.

    J Gen Virol. 1994 Nov;75 ( Pt 11):3235-40.PMID: 7964634 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Mapping and transcriptional analysis of the murine cytomegalovirus homologue of the human cytomegalovirus UL103 open reading frame.

    Lyons PA, Dallas PB, Carrello C, Shellam GR, Scalzo AA.

    Virology. 1994 Nov 1;204(2):835-9.PMID: 7941355 [PubMed - indexed for MEDLINE]Related articles

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