PubMed

Direct bone formation during distraction osteogenesis does not require TNFalpha receptors and elevated serum TNFalpha fails to inhibit bone formation in TNFR1 deficient mice.

Wahl EC, Aronson J, Liu L, Skinner RA, Miller MJ, Cockrell GE, Fowlkes JL, Thrailkill KM, Bunn RC, Ronis MJ, Lumpkin CK Jr.

Bone. 2009 Sep 17. [Epub ahead of print]PMID: 19772956 [PubMed - as supplied by publisher]Related articles

Restoration of Regenerative Osteoblastogenesis in Aged Mice: Modulation of TNF.

Wahl EC, Aronson J, Liu L, Fowlkes JL, Thrailkill KM, Bunn RC, Skinner RA, Miller MJ, Cockrell GE, Clark LM, Ou Y, Isales CM, Badger TM, Ronis MJ, Sims J, Lumpkin CK.

J Bone Miner Res. 2009 Jul 6. [Epub ahead of print]PMID: 19580462 [PubMed - as supplied by publisher]Related articles

Runt-related transcription factor 2 (RUNX2) and RUNX2-related osteogenic genes are down-regulated throughout osteogenesis in type 1 diabetes mellitus.

Fowlkes JL, Bunn RC, Liu L, Wahl EC, Coleman HN, Cockrell GE, Perrien DS, Lumpkin CK Jr, Thrailkill KM.

Endocrinology. 2008 Apr;149(4):1697-704. Epub 2007 Dec 27.PMID: 18162513 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic ethanol consumption inhibits postlactational anabolic bone rebuilding in female rats.

Shankar K, Hidestrand M, Liu X, Chen JR, Haley R, Perrien DS, Skinner RA, Lumpkin CK Jr, Badger TM, Ronis MJ.

J Bone Miner Res. 2008 Mar;23(3):338-49.PMID: 17967133 [PubMed - indexed for MEDLINE]Related articles

A novel rat model for the study of deficits in bone formation in type-2 diabetes.

Liu Z, Aronson J, Wahl EC, Liu L, Perrien DS, Kern PA, Fowlkes JL, Thrailkill KM, Bunn RC, Cockrell GE, Skinner RA, Lumpkin CK Jr.

Acta Orthop. 2007 Feb;78(1):46-55.PMID: 17453392 [PubMed - indexed for MEDLINE]Related articles

Chronic ethanol exposure inhibits distraction osteogenesis in a mouse model: role of the TNF signaling axis.

Wahl EC, Aronson J, Liu L, Liu Z, Perrien DS, Skinner RA, Badger TM, Ronis MJ, Lumpkin CK Jr.

Toxicol Appl Pharmacol. 2007 May 1;220(3):302-10. Epub 2007 Feb 24.PMID: 17391719 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel mouse model for the study of the inhibitory effects of chronic ethanol exposure on direct bone formation.

Wahl EC, Liu L, Perrien DS, Aronson J, Hogue WR, Skinner RA, Hidestrand M, Ronis MJ, Badger TM, Lumpkin CK Jr.

Alcohol. 2006 Jul;39(3):159-67. Epub 2006 Oct 2.PMID: 17127135 [PubMed - indexed for MEDLINE]Related articles

Estradiol protects against ethanol-induced bone loss by inhibiting up-regulation of receptor activator of nuclear factor-kappaB ligand in osteoblasts.

Chen JR, Haley RL, Hidestrand M, Shankar K, Liu X, Lumpkin CK, Simpson PM, Badger TM, Ronis MJ.

J Pharmacol Exp Ther. 2006 Dec;319(3):1182-90. Epub 2006 Sep 13. Erratum in: J Pharmacol Exp Ther. 2007 Feb;320(2):960. PMID: 16971503 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of systemic and local administration of recombinant human IGF-I (rhIGF-I) on de novo bone formation in an aged mouse model.

Fowlkes JL, Thrailkill KM, Liu L, Wahl EC, Bunn RC, Cockrell GE, Perrien DS, Aronson J, Lumpkin CK Jr.

J Bone Miner Res. 2006 Sep;21(9):1359-66.PMID: 16939394 [PubMed - indexed for MEDLINE]Related articlesFree article

Different molecular mechanisms underlie ethanol-induced bone loss in cycling and pregnant rats.

Shankar K, Hidestrand M, Haley R, Skinner RA, Hogue W, Jo CH, Simpson P, Lumpkin CK Jr, Aronson J, Badger TM, Ronis MJ.

Endocrinology. 2006 Jan;147(1):166-78. Epub 2005 Oct 20.PMID: 16239303 [PubMed - indexed for MEDLINE]Related articlesFree article

Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues.

Thrailkill KM, Lumpkin CK Jr, Bunn RC, Kemp SF, Fowlkes JL.

Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E735-45. Review.PMID: 16215165 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone formation is impaired in a model of type 1 diabetes.

Thrailkill KM, Liu L, Wahl EC, Bunn RC, Perrien DS, Cockrell GE, Skinner RA, Hogue WR, Carver AA, Fowlkes JL, Aronson J, Lumpkin CK Jr.

Diabetes. 2005 Oct;54(10):2875-81.PMID: 16186388 [PubMed - indexed for MEDLINE]Related articlesFree article

Ethanol-induced inhibition of bone formation in a rat model of distraction osteogenesis: a role for the tumor necrosis factor signaling axis.

Wahl EC, Perrien DS, Aronson J, Liu Z, Fletcher TW, Skinner RA, Feige U, Suva LJ, Badger TM, Lumpkin CK Jr.

Alcohol Clin Exp Res. 2005 Aug;29(8):1466-72.PMID: 16131855 [PubMed - indexed for MEDLINE]Related articles

IL-1 and TNF antagonists prevent inhibition of fracture healing by ethanol in rats.

Perrien DS, Wahl EC, Hogue WR, Feige U, Aronson J, Ronis MJ, Badger TM, Lumpkin CK Jr.

Toxicol Sci. 2004 Dec;82(2):656-60. Epub 2004 Oct 6.PMID: 15470231 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic ethanol exposure is associated with a local increase in TNF-alpha and decreased proliferation in the rat distraction gap.

Perrien DS, Liu Z, Wahl EC, Bunn RC, Skinner RA, Aronson J, Fowlkes J, Badger TM, Lumpkin CK Jr.

Cytokine. 2003 Sep 21;23(6):179-89.PMID: 12967643 [PubMed - indexed for MEDLINE]Related articles

Interleukin-1 and tumor necrosis factor antagonists attenuate ethanol-induced inhibition of bone formation in a rat model of distraction osteogenesis.

Perrien DS, Brown EC, Fletcher TW, Irby DJ, Aronson J, Gao GG, Skinner RA, Hogue WR, Feige U, Suva LJ, Ronis MJ, Badger TM, Lumpkin CK Jr.

J Pharmacol Exp Ther. 2002 Dec;303(3):904-8.PMID: 12438508 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal toxicity associated with chronic ethanol exposure in a rat model using total enteral nutrition.

Brown EC, Perrien DS, Fletcher TW, Irby DJ, Aronson J, Gao GG, Hogue WJ, Skinner RA, Suva LJ, Ronis MJ, Hakkak R, Badger TM, Lumpkin CK Jr.

J Pharmacol Exp Ther. 2002 Jun;301(3):1132-8.PMID: 12023547 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunohistochemical study of osteopontin expression during distraction osteogenesis in the rat.

Perrien DS, Brown EC, Aronson J, Skinner RA, Montague DC, Badger TM, Lumpkin CK Jr.

J Histochem Cytochem. 2002 Apr;50(4):567-74.PMID: 11897810 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal effects of developmental lead exposure in rats.

Ronis MJ, Aronson J, Gao GG, Hogue W, Skinner RA, Badger TM, Lumpkin CK Jr.

Toxicol Sci. 2001 Aug;62(2):321-9.PMID: 11452145 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of aging on distraction osteogenesis in the rat.

Aronson J, Gao GG, Shen XC, McLaren SG, Skinner RA, Badger TM, Lumpkin CK Jr.

J Orthop Res. 2001 May;19(3):421-7.PMID: 11398855 [PubMed - indexed for MEDLINE]Related articles

Development of tensile strength during distraction osteogenesis in a rat model.

Aronson J, Hogue WR, Flahiff CM, Gao GG, Shen XC, Skinner RA, Badger TM, Lumpkin CK Jr.

J Orthop Res. 2001 Jan;19(1):64-9.PMID: 11332622 [PubMed - indexed for MEDLINE]Related articles

Sustained proliferation accompanies distraction osteogenesis in the rat.

Aronson J, Shen XC, Gao GG, Miller F, Quattlebaum T, Skinner RA, Badger TM, Lumpkin CK Jr.

J Orthop Res. 1997 Jul;15(4):563-9.PMID: 9379266 [PubMed - indexed for MEDLINE]Related articles

Rat model of distraction osteogenesis.

Aronson J, Shen XC, Skinner RA, Hogue WR, Badger TM, Lumpkin CK Jr.

J Orthop Res. 1997 Mar;15(2):221-6.PMID: 9167624 [PubMed - indexed for MEDLINE]Related articles

The impact of total enteral nutrition on distraction osteogenesis in a rat model.

Lumpkin CK Jr, Aronson J, Shen XC, Gao GG, Skinner RA, Badger TM.

J Bone Miner Res. 1996 Jul;11(7):962-9.PMID: 8797117 [PubMed - indexed for MEDLINE]Related articles

Acute ethanol and selected growth suppressor transcripts in regenerating rat liver.

Lumpkin CK Jr, Moore TL, Tarpley MD, Taylor JM, Badger TM, McClung JK.

Alcohol. 1995 Jul-Aug;12(4):357-62.PMID: 7546333 [PubMed - indexed for MEDLINE]Related articles

An overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesis.

Lecka-Czernik B, Lumpkin CK Jr, Goldstein S.

Mol Cell Biol. 1995 Jan;15(1):120-8.PMID: 7799918 [PubMed - indexed for MEDLINE]Related articlesFree article

Derangements in calcium-dependent membrane currents in senescent human fibroblasts are associated with overexpression of a novel gene sequence.

Goldstein S, Liu S, Lumpkin CK Jr, Huang M, Lipschitz D, Thweatt R.

Ann N Y Acad Sci. 1994 Dec 15;747:302-12. No abstract available. PMID: 7847679 [PubMed - indexed for MEDLINE]Related articles

Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein.

Liu S, Thweatt R, Lumpkin CK Jr, Goldstein S.

Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2186-90.PMID: 8134370 [PubMed - indexed for MEDLINE]Related articlesFree article

Heat shock glycoprotein GP50: product of the retinoic acid-inducible J6 gene.

Henle KJ, Wang SY, Nagle WA, Lumpkin CK.

Exp Cell Res. 1994 Feb;210(2):185-91.PMID: 8299716 [PubMed - indexed for MEDLINE]Related articles

Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high.

Badger TM, Huang J, Ronis M, Lumpkin CK.

Biochem Biophys Res Commun. 1993 Feb 15;190(3):780-5.PMID: 8439329 [PubMed - indexed for MEDLINE]Related articles

Cytochrome P450 CYP 2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentrations in rats.

Ronis MJ, Huang J, Crouch J, Mercado C, Irby D, Valentine CR, Lumpkin CK, Ingelman-Sundberg M, Badger TM.

J Pharmacol Exp Ther. 1993 Feb;264(2):944-50.PMID: 8437134 [PubMed - indexed for MEDLINE]Related articles

Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat.

Badger TM, Ronis MJ, Lumpkin CK, Valentine CR, Shahare M, Irby D, Huang J, Mercado C, Thomas P, Ingelman-Sundberg M, et al.

J Pharmacol Exp Ther. 1993 Jan;264(1):438-47.PMID: 8423543 [PubMed - indexed for MEDLINE]Related articles

A novel gene encoding a smooth muscle protein is overexpressed in senescent human fibroblasts.

Thweatt R, Lumpkin CK Jr, Goldstein S.

Biochem Biophys Res Commun. 1992 Aug 31;187(1):1-7.PMID: 1520290 [PubMed - indexed for MEDLINE]Related articles

The effects of acute ethanol on growth in rat liver: steady state c-myc transcripts.

Lumpkin CK Jr, Taylor JM, Tarpley MD, Hayden JB, Badger TM, McClung JK.

Alcohol. 1992 May-Jun;9(3):279-82.PMID: 1605896 [PubMed - indexed for MEDLINE]Related articles

The microsomal monooxygenase system of regenerating liver. An examination of the role of estradiol in the demasculinization of drug metabolism produced by 2/3 partial hepatectomy.

Ronis MJ, Lumpkin CK, Thomas PE, Ingelman-Sundberg M, Badger TM.

Biochem Pharmacol. 1992 Feb 4;43(3):567-73.PMID: 1540214 [PubMed - indexed for MEDLINE]Related articles

Effects of short-term ethanol and nutrition on the hepatic microsomal monooxygenase system in a model utilizing total enteral nutrition in the rat.

Ronis MJ, Lumpkin CK, Ingelman-Sundberg M, Badger TM.

Alcohol Clin Exp Res. 1991 Aug;15(4):693-9.PMID: 1928645 [PubMed - indexed for MEDLINE]Related articles

Modulation of cellular glycosidase activity by hyperthermia.

Henle KJ, Shmookler Reis RJ, Lumpkin CK.

Int J Hyperthermia. 1991 May-Jun;7(3):531-7.PMID: 1833475 [PubMed - indexed for MEDLINE]Related articles

Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells.

Nuell MJ, Stewart DA, Walker L, Friedman V, Wood CM, Owens GA, Smith JR, Schneider EL, Dell' Orco R, Lumpkin CK, et al.

Mol Cell Biol. 1991 Mar;11(3):1372-81.PMID: 1996099 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of thermotolerance following microinjection of poly(A)RNA isolated from thermotolerant CHO cells.

Henle KJ, Lumpkin CK, Norris JS, Nolen GT.

Int J Hyperthermia. 1990 Nov-Dec;6(6):1041-51.PMID: 1704906 [PubMed - indexed for MEDLINE]Related articles

Heat-induced protein dephosphorylation in Chinese hamster ovary cells.

Henle KJ, Norris JS, Lumpkin CK.

Biomed Biochim Acta. 1990;49(1):35-44.PMID: 2163250 [PubMed - indexed for MEDLINE]Related articles

Isolation of a cDNA that hybrid selects antiproliferative mRNA from rat liver.

McClung JK, Danner DB, Stewart DA, Smith JR, Schneider EL, Lumpkin CK, Dell'Orco RT, Nuell MJ.

Biochem Biophys Res Commun. 1989 Nov 15;164(3):1316-22.PMID: 2480116 [PubMed - indexed for MEDLINE]Related articles

Expression of thermotolerance following microinjection of glutathione disulfide.

Lumpkin CK, Henle KJ, Sammartino G, Nolen GT, Taylor JM.

Radiat Res. 1988 Jul;115(1):202-10.PMID: 2455919 [PubMed - indexed for MEDLINE]Related articles

Mitogenic effects of the proto-oncogene and oncogene forms of c-H-ras DNA in human diploid fibroblasts.

Lumpkin CK, Knepper JE, Butel JS, Smith JR, Pereira-Smith OM.

Mol Cell Biol. 1986 Aug;6(8):2990-3.PMID: 3785220 [PubMed - indexed for MEDLINE]Related articlesFree article

Existence of high abundance antiproliferative mRNA's in senescent human diploid fibroblasts.

Lumpkin CK Jr, McClung JK, Pereira-Smith OM, Smith JR.

Science. 1986 Apr 18;232(4748):393-5.PMID: 2421407 [PubMed - indexed for MEDLINE]Related articles

Entry into S phase is inhibited in human fibroblasts by rat liver poly(A)+RNA.

Lumpkin CK Jr, McClung JK, Smith JR.

Exp Cell Res. 1985 Oct;160(2):544-9.PMID: 2412871 [PubMed - indexed for MEDLINE]Related articles

Amplification of inter-Alu extrachromosomal DNA during cellular ageing: retraction and explanation.

Shmookler Reis RJ, Lumpkin CK Jr, McGill JR, Riabowol KT, Goldstein S.

Nature. 1985 Jul 11-17;316(6024):167.PMID: 2989713 [PubMed - indexed for MEDLINE]Related articles

Extrachromosomal circular DNA and aging cells.

Lumpkin CK Jr, McGill JR, Riabowol KT, Moerman EJ, Shmookler Reis RJ, Goldstein S.

Adv Exp Med Biol. 1985;190:479-93.PMID: 3002151 [PubMed - indexed for MEDLINE]Related articles

Extrachromosomal circular copies of an 'inter-Alu' unstable sequence in human DNA are amplified during in vitro and in vivo ageing.

Shmookler Reis RJ, Lumpkin CK Jr, McGill JR, Riabowol KT, Goldstein S.

Nature. 1983 Feb 3;301(5899):394-8. No abstract available. PMID: 6823315 [PubMed - indexed for MEDLINE]Related articles

Genome alteration during in vitro and in vivo aging: amplification of extrachromosomal circular DNA molecules containing a chromosomal sequence of variable repeat frequency.

Shmookler Reis RJ, Lumpkin CK Jr, McGill JR, Riabowol KT, Goldstein S.

Cold Spring Harb Symp Quant Biol. 1983;47 Pt 2:1135-9. No abstract available. PMID: 6574863 [PubMed - indexed for MEDLINE]Related articles

Expression of herpes simplex virus type 2 antigens in premalignant and malignant human vulvar cells.

Cabral GA, Marciano-Cabral F, Fry D, Lumpkin CK, Mercer L, Goplerud D.

Am J Obstet Gynecol. 1982 Jul 15;143(6):611-9.PMID: 6283892 [PubMed - indexed for MEDLINE]Related articles