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A tale of two carboxypeptidases.

Low MJ.

Cell Metab. 2009 Nov;10(5):339-41.PMID: 19883612 [PubMed - in process]Related articles

Proopiomelanocortin expression in both GABA and glutamate neurons.

Hentges ST, Otero-Corchon V, Pennock RL, King CM, Low MJ.

J Neurosci. 2009 Oct 28;29(43):13684-90.PMID: 19864580 [PubMed - in process]Related articles

Hypothalamic orexin, OX1, alphaMSH, NPY and MCRs expression in dopaminergic D2R knockout mice.

García-Tornadú I, Díaz-Torga G, Risso GS, Silveyra P, Cataldi N, Ramirez MC, Low MJ, Libertun C, Becu-Villalobos D.

Neuropeptides. 2009 Aug;43(4):267-74. Epub 2009 Jun 30.PMID: 19570576 [PubMed - indexed for MEDLINE]Related articles

Proopiomelanocortin peptides are not essential for development of ethanol-induced behavioral sensitization.

Sharpe AL, Low MJ.

Alcohol Clin Exp Res. 2009 Jul;33(7):1202-7. Epub 2009 Apr 9.PMID: 19389193 [PubMed - in process]Related articles

Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function.

Hauge-Evans AC, King AJ, Carmignac D, Richardson CC, Robinson IC, Low MJ, Christie MR, Persaud SJ, Jones PM.

Diabetes. 2009 Feb;58(2):403-11. Epub 2008 Nov 4.PMID: 18984743 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential activation and trafficking of micro-opioid receptors in brain slices.

Arttamangkul S, Quillinan N, Low MJ, von Zastrow M, Pintar J, Williams JT.

Mol Pharmacol. 2008 Oct;74(4):972-9. Epub 2008 Jul 8.PMID: 18612077 [PubMed - indexed for MEDLINE]Related articlesFree article

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.

Gong L, Yao F, Hockman K, Heng HH, Morton GJ, Takeda K, Akira S, Low MJ, Rubinstein M, MacKenzie RG.

Endocrinology. 2008 Jul;149(7):3346-54. Epub 2008 Apr 10.PMID: 18403487 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice.

Kelly MA, Low MJ, Rubinstein M, Phillips TJ.

Genes Brain Behav. 2008 Jul;7(5):568-77.PMID: 18363855 [PubMed - indexed for MEDLINE]Related articlesFree article

Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice.

Doherty JM, Masten VL, Powell SB, Ralph RJ, Klamer D, Low MJ, Geyer MA.

Neuropsychopharmacology. 2008 Oct;33(11):2648-56. Epub 2007 Dec 12.PMID: 18075489 [PubMed - indexed for MEDLINE]Related articlesFree article

Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus.

Appleyard SM, Marks D, Kobayashi K, Okano H, Low MJ, Andresen MC.

J Neurosci. 2007 Nov 28;27(48):13292-302.PMID: 18045923 [PubMed - indexed for MEDLINE]Related articlesFree article

Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene.

Santangelo AM, de Souza FS, Franchini LF, Bumaschny VF, Low MJ, Rubinstein M.

PLoS Genet. 2007 Oct;3(10):1813-26.PMID: 17922573 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice.

Tolle V, Low MJ.

Diabetes. 2008 Jan;57(1):86-94. Epub 2007 Oct 1.PMID: 17909095 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional regulation of pituitary POMC is conserved at the vertebrate extremes despite great promoter sequence divergence.

Bumaschny VF, de Souza FS, López Leal RA, Santangelo AM, Baetscher M, Levi DH, Low MJ, Rubinstein M.

Mol Endocrinol. 2007 Nov;21(11):2738-49. Epub 2007 Aug 14.PMID: 17698954 [PubMed - indexed for MEDLINE]Related articlesFree article

The absence of endogenous beta-endorphin selectively blocks phosphorylation and desensitization of mu opioid receptors following partial sciatic nerve ligation.

Petraschka M, Li S, Gilbert TL, Westenbroek RE, Bruchas MR, Schreiber S, Lowe J, Low MJ, Pintar JE, Chavkin C.

Neuroscience. 2007 Jun 8;146(4):1795-807. Epub 2007 Apr 30.PMID: 17467916 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating.

Vinkers CH, Risbrough VB, Geyer MA, Caldwell S, Low MJ, Hauger RL.

Pharmacol Biochem Behav. 2007 Mar;86(3):550-8. Epub 2007 Jan 31.PMID: 17324452 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential involvement of endogenous opioids in sucrose consumption and food reinforcement.

Hayward MD, Schaich-Borg A, Pintar JE, Low MJ.

Pharmacol Biochem Behav. 2006 Nov;85(3):601-11. Epub 2006 Dec 12.PMID: 17166571 [PubMed - indexed for MEDLINE]Related articlesFree article

Central dysregulation of the hypothalamic-pituitary-adrenal axis in neuron-specific proopiomelanocortin-deficient mice.

Smart JL, Tolle V, Otero-Corchon V, Low MJ.

Endocrinology. 2007 Feb;148(2):647-59. Epub 2006 Nov 9.PMID: 17095588 [PubMed - indexed for MEDLINE]Related articlesFree article

The contribution of endogenous opioids to food reward is dependent on sex and background strain.

Hayward MD, Low MJ.

Neuroscience. 2007 Jan 5;144(1):17-25. Epub 2006 Oct 13.PMID: 17049174 [PubMed - indexed for MEDLINE]Related articles

Somatostatin receptors in wildtype and somatostatin deficient mice and their involvement in nitric oxide physiology in the retina.

Mastrodimou N, Vasilaki A, Papadioti A, Low MJ, Hoyer D, Thermos K.

Neuropeptides. 2006 Oct;40(5):365-73. Epub 2006 Sep 28.PMID: 17010429 [PubMed - indexed for MEDLINE]Related articles

GH in the dwarf dopaminergic D2 receptor knockout mouse: somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin.

García-Tornadú I, Rubinstein M, Gaylinn BD, Hill D, Arany E, Low MJ, Díaz-Torga G, Becu-Villalobos D.

J Endocrinol. 2006 Sep;190(3):611-9.PMID: 17003262 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice.

Risbrough VB, Masten VL, Caldwell S, Paulus MP, Low MJ, Geyer MA.

Neuropsychopharmacology. 2006 Nov;31(11):2349-58. Epub 2006 Jul 19.PMID: 16855533 [PubMed - indexed for MEDLINE]Related articlesFree article

Dopaminergic D2 receptor knockout mouse: an animal model of prolactinoma.

Cristina C, García-Tornadú I, Díaz-Torga G, Rubinstein M, Low MJ, Becú-Villalobos D.

Front Horm Res. 2006;35:50-63. Review.PMID: 16809922 [PubMed - indexed for MEDLINE]Related articles

Reduced basal and ethanol stimulation of striatal extracellular dopamine concentrations in dopamine D2 receptor knockout mice.

Job MO, Ramachandra V, Anders S, Low MJ, Gonzales RA.

Synapse. 2006 Aug;60(2):158-64.PMID: 16715495 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice.

Smart JL, Tolle V, Low MJ.

J Clin Invest. 2006 Feb;116(2):495-505. Epub 2006 Jan 26. Erratum in: J Clin Invest. 2006 Mar;116(3):842. PMID: 16440060 [PubMed - indexed for MEDLINE]Related articlesFree article

Gonadotroph-specific expression of the human follicle stimulating hormone beta gene in transgenic mice.

Kumar TR, Schuff KG, Nusser KD, Low MJ.

Mol Cell Endocrinol. 2006 Mar 9;247(1-2):103-15. Epub 2006 Jan 18.PMID: 16414183 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of synaptic inputs by constitutively released endocannabinoids and exogenous cannabinoids.

Hentges ST, Low MJ, Williams JT.

J Neurosci. 2005 Oct 19;25(42):9746-51.PMID: 16237178 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice.

Elmer GI, Pieper JO, Levy J, Rubinstein M, Low MJ, Grandy DK, Wise RA.

Psychopharmacology (Berl). 2005 Oct;182(1):33-44. Epub 2005 Sep 29.PMID: 16136297 [PubMed - indexed for MEDLINE]Related articles

Naloxone's suppression of spontaneous and food-conditioned locomotor activity is diminished in mice lacking either the dopamine D(2) receptor or enkephalin.

Hayward MD, Low MJ.

Brain Res Mol Brain Res. 2005 Oct 31;140(1-2):91-8. Epub 2005 Aug 26.PMID: 16125819 [PubMed - indexed for MEDLINE]Related articles

Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes.

de Souza FS, Bumaschny VF, Low MJ, Rubinstein M.

Mol Biol Evol. 2005 Dec;22(12):2417-27. Epub 2005 Aug 10.PMID: 16093565 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice.

Cristina C, Díaz-Torga G, Baldi A, Góngora A, Rubinstein M, Low MJ, Becú-Villalobos D.

Endocrinology. 2005 Jul;146(7):2952-62. Epub 2005 Apr 7.PMID: 15817666 [PubMed - indexed for MEDLINE]Related articlesFree article

Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids.

Appleyard SM, Bailey TW, Doyle MW, Jin YH, Smart JL, Low MJ, Andresen MC.

J Neurosci. 2005 Apr 6;25(14):3578-85.PMID: 15814788 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting.

de Souza FS, Santangelo AM, Bumaschny V, Avale ME, Smart JL, Low MJ, Rubinstein M.

Mol Cell Biol. 2005 Apr;25(8):3076-86.PMID: 15798195 [PubMed - indexed for MEDLINE]Related articlesFree article

Preservation of eumelanin hair pigmentation in proopiomelanocortin-deficient mice on a nonagouti (a/a) genetic background.

Slominski A, Plonka PM, Pisarchik A, Smart JL, Tolle V, Wortsman J, Low MJ.

Endocrinology. 2005 Mar;146(3):1245-53. Epub 2004 Nov 24.PMID: 15564334 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical endocrinology and metabolism. The somatostatin neuroendocrine system: physiology and clinical relevance in gastrointestinal and pancreatic disorders.

Low MJ.

Best Pract Res Clin Endocrinol Metab. 2004 Dec;18(4):607-22. Review.PMID: 15533778 [PubMed - indexed for MEDLINE]Related articles

Role of proopiomelanocortin neurons and peptides in the regulation of energy homeostasis.

Low MJ.

J Endocrinol Invest. 2004;27(6 Suppl):95-100.PMID: 15481808 [PubMed - indexed for MEDLINE]Related articles

Operant self-administration of ethanol in C57BL/6 mice lacking beta-endorphin and enkephalin.

Hayward MD, Hansen ST, Pintar JE, Low MJ.

Pharmacol Biochem Behav. 2004 Sep;79(1):171-81.PMID: 15388297 [PubMed - indexed for MEDLINE]Related articles

Strategies for cellular identification in nucleus tractus solitarius slices.

Doyle MW, Bailey TW, Jin YH, Appleyard SM, Low MJ, Andresen MC.

J Neurosci Methods. 2004 Aug 15;137(1):37-48.PMID: 15196825 [PubMed - indexed for MEDLINE]Related articles

A transgenic marker for newly born granule cells in dentate gyrus.

Overstreet LS, Hentges ST, Bumaschny VF, de Souza FS, Smart JL, Santangelo AM, Low MJ, Westbrook GL, Rubinstein M.

J Neurosci. 2004 Mar 31;24(13):3251-9.PMID: 15056704 [PubMed - indexed for MEDLINE]Related articlesFree article

GABA release from proopiomelanocortin neurons.

Hentges ST, Nishiyama M, Overstreet LS, Stenzel-Poore M, Williams JT, Low MJ.

J Neurosci. 2004 Feb 18;24(7):1578-83.PMID: 14973227 [PubMed - indexed for MEDLINE]Related articlesFree article

The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder.

Avale ME, Falzone TL, Gelman DM, Low MJ, Grandy DK, Rubinstein M.

Mol Psychiatry. 2004 Jul;9(7):718-26.PMID: 14699433 [PubMed - indexed for MEDLINE]Related articles

The mapping of quantitative trait loci underlying strain differences in locomotor activity between 129S6 and C57BL/6J mice.

Kelly MA, Low MJ, Phillips TJ, Wakeland EK, Yanagisawa M.

Mamm Genome. 2003 Oct;14(10):692-702.PMID: 14694905 [PubMed - indexed for MEDLINE]Related articles

Comparative phenotypic resolution of spontaneous, D2-like and D1-like agonist-induced orofacial movement topographies in congenic mutants with dopamine D2 vs. D3 receptor "knockout".

Tomiyama K, McNamara FN, Clifford JJ, Kinsella A, Drago J, Fuchs S, Grandy DK, Low MJ, Rubinstein M, Tighe O, Croke DT, Koshikawa N, Waddington JL.

Synapse. 2004 Jan;51(1):71-81.PMID: 14579426 [PubMed - indexed for MEDLINE]Related articles

Treatment of Helicobacter gastritis with IL-4 requires somatostatin.

Zavros Y, Rathinavelu S, Kao JY, Todisco A, Del Valle J, Weinstock JV, Low MJ, Merchant JL.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12944-9. Epub 2003 Oct 10.PMID: 14555768 [PubMed - indexed for MEDLINE]Related articlesFree article

Laminin inhibits lactotroph proliferation and is reduced in early prolactinoma development.

Kuchenbauer F, Theodoropoulou M, Hopfner U, Stalla J, Renner U, Tonn JC, Low MJ, Arzt E, Stalla GK, Páez-Pereda M.

Mol Cell Endocrinol. 2003 Sep 30;207(1-2):13-20.PMID: 12972179 [PubMed - indexed for MEDLINE]Related articles

Transgenic mice engineered to target Cre/loxP-mediated DNA recombination into catecholaminergic neurons.

Gelman DM, Noaín D, Avale ME, Otero V, Low MJ, Rubinstein M.

Genesis. 2003 Aug;36(4):196-202.PMID: 12929090 [PubMed - indexed for MEDLINE]Related articles

Lack of proopiomelanocortin peptides results in obesity and defective adrenal function but normal melanocyte pigmentation in the murine C57BL/6 genetic background.

Smart JL, Low MJ.

Ann N Y Acad Sci. 2003 Jun;994:202-10.PMID: 12851317 [PubMed - indexed for MEDLINE]Related articles

State-dependent modulation of feeding behavior by proopiomelanocortin-derived beta-endorphin.

Low MJ, Hayward MD, Appleyard SM, Rubinstein M.

Ann N Y Acad Sci. 2003 Jun;994:192-201.PMID: 12851316 [PubMed - indexed for MEDLINE]Related articles

Central serotonin and melanocortin pathways regulating energy homeostasis.

Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Zigman JM, Cone RD, Elmquist JK.

Ann N Y Acad Sci. 2003 Jun;994:169-74. Review.PMID: 12851313 [PubMed - indexed for MEDLINE]Related articles

Effects of a Drd2 deletion mutation on ethanol-induced locomotor stimulation and sensitization suggest a role for epistasis.

Palmer AA, Low MJ, Grandy DK, Phillips TJ.

Behav Genet. 2003 May;33(3):311-24.PMID: 12837020 [PubMed - indexed for MEDLINE]Related articles

Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice.

Katz JL, Chausmer AL, Elmer GI, Rubinstein M, Low MJ, Grandy DK.

Psychopharmacology (Berl). 2003 Oct;170(1):108-14. Epub 2003 May 29.PMID: 12783155 [PubMed - indexed for MEDLINE]Related articles