PubMed

CCR6 is required for IL-23-induced psoriasis-like inflammation in mice.

Hedrick MN, Lonsdorf AS, Shirakawa AK, Richard Lee CC, Liao F, Singh SP, Zhang HH, Grinberg A, Love PE, Hwang ST, Farber JM.

J Clin Invest. 2009 Aug;119(8):2317-29.PMID: 19662682 [PubMed - indexed for MEDLINE]Related articlesFree article

Themis, a T cell-specific protein important for late thymocyte development.

Lesourne R, Uehara S, Lee J, Song KD, Li L, Pinkhasov J, Zhang Y, Weng NP, Wildt KF, Wang L, Bosselut R, Love PE.

Nat Immunol. 2009 Aug;10(8):840-7. Epub 2009 Jul 13.PMID: 19597498 [PubMed - indexed for MEDLINE]Related articles

The cytoplasmic tail of the T cell receptor CD3 epsilon subunit contains a phospholipid-binding motif that regulates T cell functions.

Deford-Watts LM, Tassin TC, Becker AM, Medeiros JJ, Albanesi JP, Love PE, Wülfing C, van Oers NS.

J Immunol. 2009 Jul 15;183(2):1055-64. Epub 2009 Jun 19.PMID: 19542373 [PubMed - indexed for MEDLINE]Related articles

LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth.

Tzchori I, Day TF, Carolan PJ, Zhao Y, Wassif CA, Li L, Lewandoski M, Gorivodsky M, Love PE, Porter FD, Westphal H, Yang Y.

Development. 2009 Apr;136(8):1375-85.PMID: 19304889 [PubMed - indexed for MEDLINE]Related articlesFree article

Bam32: a novel mediator of Erk activation in T cells.

Sommers CL, Gurson JM, Surana R, Barda-Saad M, Lee J, Kishor A, Li W, Gasser AJ, Barr VA, Miyaji M, Love PE, Samelson LE.

Int Immunol. 2008 Jul;20(7):811-8. Epub 2008 Apr 29.PMID: 18448454 [PubMed - indexed for MEDLINE]Related articlesFree article

Tyrosine phosphorylation controls nuclear localization and transcriptional activity of Ssdp1 in mammalian cells.

Dey-Guha I, Malik N, Lesourne R, Love PE, Westphal H.

J Cell Biochem. 2008 Apr 15;103(6):1856-65.PMID: 18080319 [PubMed - indexed for MEDLINE]Related articles

A retrospective on the requirements for gammadelta T-cell development.

Hayes SM, Love PE.

Immunol Rev. 2007 Feb;215:8-14. Review.PMID: 17291275 [PubMed - indexed for MEDLINE]Related articles

Selective thymus settling regulated by cytokine and chemokine receptors.

Schwarz BA, Sambandam A, Maillard I, Harman BC, Love PE, Bhandoola A.

J Immunol. 2007 Feb 15;178(4):2008-17.PMID: 17277104 [PubMed - indexed for MEDLINE]Related articlesFree article

Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.

Erman B, Alag AS, Dahle O, van Laethem F, Sarafova SD, Guinter TI, Sharrow SO, Grinberg A, Love PE, Singer A.

J Immunol. 2006 Nov 15;177(10):6613-25.PMID: 17082573 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium.

Staton TL, Habtezion A, Winslow MM, Sato T, Love PE, Butcher EC.

Nat Immunol. 2006 May;7(5):482-8. Epub 2006 Apr 2. Erratum in: Nat Immunol. 2006 Jun;7(6):672. PMID: 16582913 [PubMed - indexed for MEDLINE]Related articles

The multifunctional RNA-binding protein La is required for mouse development and for the establishment of embryonic stem cells.

Park JM, Kohn MJ, Bruinsma MW, Vech C, Intine RV, Fuhrmann S, Grinberg A, Mukherjee I, Love PE, Ko MS, DePamphilis ML, Maraia RJ.

Mol Cell Biol. 2006 Feb;26(4):1445-51.PMID: 16449655 [PubMed - indexed for MEDLINE]Related articlesFree article

Strength of signal: a fundamental mechanism for cell fate specification.

Hayes SM, Love PE.

Immunol Rev. 2006 Feb;209:170-5. Review.PMID: 16448542 [PubMed - indexed for MEDLINE]Related articles

Stoichiometry of the murine gammadelta T cell receptor.

Hayes SM, Love PE.

J Exp Med. 2006 Jan 23;203(1):47-52. Epub 2006 Jan 17.PMID: 16418397 [PubMed - indexed for MEDLINE]Related articlesFree article

Premature expression of chemokine receptor CCR9 impairs T cell development.

Uehara S, Hayes SM, Li L, El-Khoury D, Canelles M, Fowlkes BJ, Love PE.

J Immunol. 2006 Jan 1;176(1):75-84.PMID: 16365398 [PubMed - indexed for MEDLINE]Related articlesFree article

Clathrin adaptor AP-2 is essential for early embryonal development.

Mitsunari T, Nakatsu F, Shioda N, Love PE, Grinberg A, Bonifacino JS, Ohno H.

Mol Cell Biol. 2005 Nov;25(21):9318-23.PMID: 16227583 [PubMed - indexed for MEDLINE]Related articlesFree article

TCR signal strength influences alphabeta/gammadelta lineage fate.

Hayes SM, Li L, Love PE.

Immunity. 2005 May;22(5):583-93.PMID: 15894276 [PubMed - indexed for MEDLINE]Related articles

Selective expression of the 21-kilodalton tyrosine-phosphorylated form of TCR zeta promotes the emergence of T cells with autoreactive potential.

Pitcher LA, Mathis MA, Subramanian S, Young JA, Wakeland EK, Love PE, van Oers NS.

J Immunol. 2005 May 15;174(10):6071-9.PMID: 15879101 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection.

Sommers CL, Lee J, Steiner KL, Gurson JM, Depersis CL, El-Khoury D, Fuller CL, Shores EW, Love PE, Samelson LE.

J Exp Med. 2005 Apr 4;201(7):1125-34. Epub 2005 Mar 28.PMID: 15795236 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes.

Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE.

Gene Expr Patterns. 2004 May;4(3):315-20.PMID: 15053981 [PubMed - indexed for MEDLINE]Related articles

LAT: a T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways.

Sommers CL, Samelson LE, Love PE.

Bioessays. 2004 Jan;26(1):61-7. Review.PMID: 14696041 [PubMed - indexed for MEDLINE]Related articles

Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice.

Cerritelli SM, Frolova EG, Feng C, Grinberg A, Love PE, Crouch RJ.

Mol Cell. 2003 Mar;11(3):807-15.PMID: 12667461 [PubMed - indexed for MEDLINE]Related articles

Regulation of thymocyte development: only the meek survive.

Love PE, Chan AC.

Curr Opin Immunol. 2003 Apr;15(2):199-203. Review.PMID: 12633670 [PubMed - indexed for MEDLINE]Related articles

An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors.

Hayes SM, Shores EW, Love PE.

Immunol Rev. 2003 Feb;191:28-37. Review.PMID: 12614349 [PubMed - indexed for MEDLINE]Related articles

Signaling through MHC in transgenic mice generates a population of memory phenotype cytolytic cells that lack TCR.

McFarland HI, Hansal SA, Morris DI, McVicar DW, Love PE, Rosenberg AS.

Blood. 2003 Jun 1;101(11):4520-8. Epub 2003 Feb 13.PMID: 12586613 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation-induced modification in the CD3 complex of the gammadelta T cell receptor.

Hayes SM, Laky K, El-Khoury D, Kappes DJ, Fowlkes BJ, Love PE.

J Exp Med. 2002 Nov 18;196(10):1355-61. Erratum in: J Exp Med 2002 Dec 16;196(12):1653. PMID: 12438426 [PubMed - indexed for MEDLINE]Related articlesFree article

Imprint control element-mediated secondary methylation imprints at the Igf2/H19 locus.

Srivastava M, Frolova E, Rottinghaus B, Boe SP, Grinberg A, Lee E, Love PE, Pfeifer K.

J Biol Chem. 2003 Feb 21;278(8):5977-83. Epub 2002 Sep 20.PMID: 12270940 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct structure and signaling potential of the gamma delta TCR complex.

Hayes SM, Love PE.

Immunity. 2002 Jun;16(6):827-38.PMID: 12121664 [PubMed - indexed for MEDLINE]Related articles

CD5-mediated inhibition of TCR signaling during intrathymic selection and development does not require the CD5 extracellular domain.

Bhandoola A, Bosselut R, Yu Q, Cowan ML, Feigenbaum L, Love PE, Singer A.

Eur J Immunol. 2002 Jun;32(6):1811-7.PMID: 12115665 [PubMed - indexed for MEDLINE]Related articles

A LAT mutation that inhibits T cell development yet induces lymphoproliferation.

Sommers CL, Park CS, Lee J, Feng C, Fuller CL, Grinberg A, Hildebrand JA, Lacaná E, Menon RK, Shores EW, Samelson LE, Love PE.

Science. 2002 Jun 14;296(5575):2040-3.PMID: 12065840 [PubMed - indexed for MEDLINE]Related articlesFree article

A potential role for CD69 in thymocyte emigration.

Feng C, Woodside KJ, Vance BA, El-Khoury D, Canelles M, Lee J, Gress R, Fowlkes BJ, Shores EW, Love PE.

Int Immunol. 2002 Jun;14(6):535-44.PMID: 12039905 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for CCR9 in T lymphocyte development and migration.

Uehara S, Grinberg A, Farber JM, Love PE.

J Immunol. 2002 Mar 15;168(6):2811-9.PMID: 11884450 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of CCR9 expression and CCL25/thymus-expressed chemokine responsiveness during T cell development: CD3(high)CD69+ thymocytes and gammadeltaTCR+ thymocytes preferentially respond to CCL25.

Uehara S, Song K, Farber JM, Love PE.

J Immunol. 2002 Jan 1;168(1):134-42.PMID: 11751956 [PubMed - indexed for MEDLINE]Related articlesFree article

Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development.

Sommers CL, Menon RK, Grinberg A, Zhang W, Samelson LE, Love PE.

J Exp Med. 2001 Jul 16;194(2):135-42.PMID: 11457888 [PubMed - indexed for MEDLINE]Related articlesFree article

Fine tuning of TCR signaling by CD5.

Azzam HS, DeJarnette JB, Huang K, Emmons R, Park CS, Sommers CL, El-Khoury D, Shores EW, Love PE.

J Immunol. 2001 May 1;166(9):5464-72.PMID: 11313384 [PubMed - indexed for MEDLINE]Related articlesFree article

Function of CD3 epsilon-mediated signals in T cell development.

Sommers CL, Dejarnette JB, Huang K, Lee J, El-Khoury D, Shores EW, Love PE.

J Exp Med. 2000 Sep 18;192(6):913-19.PMID: 10993922 [PubMed - indexed for MEDLINE]Related articlesFree article

Critical relationship between TCR signaling potential and TCR affinity during thymocyte selection.

Love PE, Lee J, Shores EW.

J Immunol. 2000 Sep 15;165(6):3080-7.PMID: 10975819 [PubMed - indexed for MEDLINE]Related articlesFree article

ITAM multiplicity and thymocyte selection: how low can you go?

Love PE, Shores EW.

Immunity. 2000 Jun;12(6):591-7. Review. No abstract available. PMID: 10894159 [PubMed - indexed for MEDLINE]Related articles

LAT is essential for Fc(epsilon)RI-mediated mast cell activation.

Saitoh S, Arudchandran R, Manetz TS, Zhang W, Sommers CL, Love PE, Rivera J, Samelson LE.

Immunity. 2000 May;12(5):525-35.PMID: 10843385 [PubMed - indexed for MEDLINE]Related articles

RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation.

Rajagopal K, Sommers CL, Decker DC, Mitchell EO, Korthauer U, Sperling AI, Kozak CA, Love PE, Bluestone JA.

J Exp Med. 1999 Dec 6;190(11):1657-68.PMID: 10587356 [PubMed - indexed for MEDLINE]Related articlesFree article

LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.

Pasquet JM, Gross B, Quek L, Asazuma N, Zhang W, Sommers CL, Schweighoffer E, Tybulewicz V, Judd B, Lee JR, Koretzky G, Love PE, Samelson LE, Watson SP.

Mol Cell Biol. 1999 Dec;19(12):8326-34.PMID: 10567557 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection.

Sommers CL, Rabin RL, Grinberg A, Tsay HC, Farber J, Love PE.

J Exp Med. 1999 Nov 15;190(10):1427-38.PMID: 10562318 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of the SHP-1 tyrosine phosphatase in regulation of T cell selection.

Zhang J, Somani AK, Yuen D, Yang Y, Love PE, Siminovitch KA.

J Immunol. 1999 Sep 15;163(6):3012-21.PMID: 10477564 [PubMed - indexed for MEDLINE]Related articlesFree article

Introduction

Love PE, Shores EW.

Semin Immunol. 1999 Aug;11(4):225-6. No abstract available. PMID: 10441208 [PubMed - as supplied by publisher]Related articles

Essential role of LAT in T cell development.

Zhang W, Sommers CL, Burshtyn DN, Stebbins CC, DeJarnette JB, Trible RP, Grinberg A, Tsay HC, Jacobs HM, Kessler CM, Long EO, Love PE, Samelson LE.

Immunity. 1999 Mar;10(3):323-32.PMID: 10204488 [PubMed - indexed for MEDLINE]Related articles

CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.

Azzam HS, Grinberg A, Lui K, Shen H, Shores EW, Love PE.

J Exp Med. 1998 Dec 21;188(12):2301-11.PMID: 9858516 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific requirement for CD3epsilon in T cell development.

DeJarnette JB, Sommers CL, Huang K, Woodside KJ, Emmons R, Katz K, Shores EW, Love PE.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14909-14.PMID: 9843989 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of antigen-specific hyporesponsiveness by transplantation of hemopoietic cells containing an MHC class I transgene regulated by a lymphocyte-specific promoter.

Hansal SA, Morris DI, Sechler JM, Love PE, Rosenberg AS.

J Immunol. 1998 Aug 1;161(3):1063-8.PMID: 9686561 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell development in mice lacking all T cell receptor zeta family members (Zeta, eta, and FcepsilonRIgamma).

Shores EW, Ono M, Kawabe T, Sommers CL, Tran T, Lui K, Udey MC, Ravetch J, Love PE.

J Exp Med. 1998 Apr 6;187(7):1093-101.PMID: 9529325 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of an associated 16-kDa tyrosine phosphoprotein required for Ly-49D signal transduction.

Mason LH, Willette-Brown J, Anderson SK, Gosselin P, Shores EW, Love PE, Ortaldo JR, McVicar DW.

J Immunol. 1998 May 1;160(9):4148-52.PMID: 9574512 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs.

van Oers NS, Love PE, Shores EW, Weiss A.

J Immunol. 1998 Jan 1;160(1):163-70.PMID: 9551968 [PubMed - indexed for MEDLINE]Related articlesFree article