PubMed

Missense mutations in a retinal pigment epithelium protein, bestrophin-1, cause retinitis pigmentosa.

Davidson AE, Millar ID, Urquhart JE, Burgess-Mullan R, Shweikh Y, Parry N, O'Sullivan J, Maher GJ, McKibbin M, Downes SM, Lotery AJ, Jacobson SG, Brown PD, Black GC, Manson FD.

Am J Hum Genet. 2009 Nov;85(5):581-92. Epub 2009 Oct 22.PMID: 19853238 [PubMed - in process]Related articles

Generation of light-sensitive photoreceptor phenotypes by genetic modification of human adult ocular stem cells using Crx.

Jomary C, Jones SE, Lotery A.

Invest Ophthalmol Vis Sci. 2009 Oct 22. [Epub ahead of print]PMID: 19850845 [PubMed - as supplied by publisher]Related articles

The promise of nanomedicine for ocular disease.

Thomson H, Lotery A.

Nanomed. 2009 Aug;4(6):599-604. No abstract available. PMID: 19663586 [PubMed - indexed for MEDLINE]Related articles

Fibulin 5 forms a compact dimer in physiological solutions.

Jones RP, Wang MC, Jowitt TA, Ridley C, Mellody KT, Howard M, Wang T, Bishop PN, Lotery AJ, Kielty CM, Baldock C, Trump D.

J Biol Chem. 2009 Sep 18;284(38):25938-43. Epub 2009 Jul 17.PMID: 19617354 [PubMed - indexed for MEDLINE]Related articlesFree article

Homozygosity mapping reveals PDE6C mutations in patients with early-onset cone photoreceptor disorders.

Thiadens AA, den Hollander AI, Roosing S, Nabuurs SB, Zekveld-Vroon RC, Collin RW, De Baere E, Koenekoop RK, van Schooneveld MJ, Strom TM, van Lith-Verhoeven JJ, Lotery AJ, van Moll-Ramirez N, Leroy BP, van den Born LI, Hoyng CB, Cremers FP, Klaver CC.

Am J Hum Genet. 2009 Aug;85(2):240-7. Epub 2009 Jul 16.PMID: 19615668 [PubMed - indexed for MEDLINE]Related articles

Localization of complement 1 inhibitor (C1INH/SERPING1) in human eyes with age-related macular degeneration.

Mullins RF, Faidley EA, Daggett HT, Jomary C, Lotery AJ, Stone EM.

Exp Eye Res. 2009 Nov;89(5):767-73. Epub 2009 Jul 14.PMID: 19607829 [PubMed - in process]Related articles

Support for the involvement of complement factor I in age-related macular degeneration.

Ennis S, Gibson J, Cree AJ, Collins A, Lotery AJ.

Eur J Hum Genet. 2009 Jul 15. [Epub ahead of print] No abstract available. PMID: 19603066 [PubMed - as supplied by publisher]Related articles

Prevalence of myocilin gene mutations in a novel UK cohort of POAG patients.

Ennis S, Gibson J, Griffiths H, Bunyan D, Cree AJ, Robinson D, Self J, Macleod A, Lotery A.

Eye (Lond). 2009 May 1. [Epub ahead of print]PMID: 19407846 [PubMed - as supplied by publisher]Related articles

Frmd7 expression in developing mouse brain.

Self J, Haitchi HM, Griffiths H, Holgate ST, Davies DE, Lotery A.

Eye (Lond). 2009 Mar 6. [Epub ahead of print]PMID: 19265863 [PubMed - as supplied by publisher]Related articles

Novel software to self-monitor central serous retinopathy.

Turnbull AM, Abu-Ain MS, Lash SC, Murphy AS, Lotery AJ.

Eye (Lond). 2009 Feb 27. [Epub ahead of print] No abstract available. PMID: 19247387 [PubMed - as supplied by publisher]Related articles

Infantile nystagmus and late onset ataxia associated with a CACNA1A mutation in the intracellular loop between s4 and s5 of domain 3.

Self J, Mercer C, Boon EM, Murugavel M, Shawkat F, Hammans S, Hodgkins P, Griffiths H, Lotery A.

Eye (Lond). 2009 Jan 30. [Epub ahead of print]PMID: 19182766 [PubMed - as supplied by publisher]Related articles

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.

Ennis S, Jomary C, Mullins R, Cree A, Chen X, Macleod A, Jones S, Collins A, Stone E, Lotery A.

Lancet. 2008 Nov 22;372(9652):1828-34. Epub 2008 Oct 6.PMID: 18842294 [PubMed - indexed for MEDLINE]Related articles

Progress in understanding and treating age-related macular degeneration.

Lotery A.

Eye (Lond). 2008 Jun;22(6):739-41. No abstract available. PMID: 18548082 [PubMed - indexed for MEDLINE]Related articles

Age-related macular degeneration is associated with the HLA-Cw*0701 Genotype and the natural killer cell receptor AA haplotype.

Goverdhan SV, Khakoo SI, Gaston H, Chen X, Lotery AJ.

Invest Ophthalmol Vis Sci. 2008 Nov;49(11):5077-82. Epub 2008 May 30.PMID: 18515573 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration.

Goverdhan SV, Ennis S, Hannan SR, Madhusudhana KC, Cree AJ, Luff AJ, Lotery AJ.

Br J Ophthalmol. 2008 Apr;92(4):537-40. Epub 2008 Feb 29.PMID: 18310311 [PubMed - indexed for MEDLINE]Related articles

A review of the molecular genetics of congenital Idiopathic Nystagmus (CIN).

Self J, Lotery A.

Ophthalmic Genet. 2007 Dec;28(4):187-91. Review.PMID: 18161616 [PubMed - indexed for MEDLINE]Related articles

Economic burden of bilateral neovascular age-related macular degeneration: multi-country observational study.

Cruess AF, Zlateva G, Xu X, Soubrane G, Pauleikhoff D, Lotery A, Mones J, Buggage R, Schaefer C, Knight T, Goss TF.

Pharmacoeconomics. 2008;26(1):57-73.PMID: 18088159 [PubMed - indexed for MEDLINE]Related articles

Autosomal dominant early onset aponeurotic ptosis and corneal limbal vascularization in a three-generation family.

Ismail AR, Cates CA, Mullins RF, Manners RM, Lotery AJ.

Ophthal Plast Reconstr Surg. 2007 Nov-Dec;23(6):484-6.PMID: 18030124 [PubMed - indexed for MEDLINE]Related articles

Idiopathic juxtafoveolar retinal telangiectasis in monozygotic twins.

Hannan SR, Madhusudhana KC, Rennie C, Lotery AJ.

Br J Ophthalmol. 2007 Dec;91(12):1729-30. No abstract available. PMID: 18024833 [PubMed - indexed for MEDLINE]Related articles

Intravitreal bevacizumab (Avastin) for the treatment of choroidal neovascularization in age-related macular degeneration: results from 118 cases.

Madhusudhana KC, Hannan SR, Williams CP, Goverdhan SV, Rennie C, Lotery AJ, Luff AJ, Newsom RS.

Br J Ophthalmol. 2007 Dec;91(12):1716-7. No abstract available. PMID: 18024821 [PubMed - indexed for MEDLINE]Related articles

Allelic variation of the FRMD7 gene in congenital idiopathic nystagmus.

Self JE, Shawkat F, Malpas CT, Thomas NS, Harris CM, Hodgkins PR, Chen X, Trump D, Lotery AJ.

Arch Ophthalmol. 2007 Sep;125(9):1255-63.PMID: 17846367 [PubMed - indexed for MEDLINE]Related articlesFree article

Burden and health care resource utilization in neovascular age-related macular degeneration: findings of a multicountry study.

Soubrane G, Cruess A, Lotery A, Pauleikhoff D, Monès J, Xu X, Zlateva G, Buggage R, Conlon J, Goss TF.

Arch Ophthalmol. 2007 Sep;125(9):1249-54.PMID: 17846366 [PubMed - indexed for MEDLINE]Related articlesFree article

Age and cataract surgery complications.

Konstantopoulos A, Madhusudhana K, Yadegarfar G, Lotery A.

Br J Ophthalmol. 2007 Sep;91(9):1254; author reply 1254-5. No abstract available. Erratum in: Br J Ophthalmol. 2007 Nov;91(11):1572. Bosley, Thomas M [removed]; Konstantopoulos, Aris [added]; Madhusudhana, Krishnappa [added]; Yadegarfar, Ghasem [added]; Lotery, Andrew [added]. PMID: 17709595 [PubMed - indexed for MEDLINE]Related articles

Progress in defining the molecular biology of age related macular degeneration.

Lotery A, Trump D.

Hum Genet. 2007 Nov;122(3-4):219-36. Epub 2007 Jul 21. Review.PMID: 17659362 [PubMed - indexed for MEDLINE]Related articles

Retinal pigment epithelial tear following intravitreal bevacizumab for choroidal neovascular membrane due to age-related macular degeneration.

Hannan SR, Madhusudhana KC, Lotery AJ, Newsom RS.

Br J Ophthalmol. 2007 Jul;91(7):977-8. No abstract available. PMID: 17576713 [PubMed - indexed for MEDLINE]Related articles

Burden of illness, visual impairment and health resource utilisation of patients with neovascular age-related macular degeneration: results from the UK cohort of a five-country cross-sectional study.

Lotery A, Xu X, Zlatava G, Loftus J.

Br J Ophthalmol. 2007 Oct;91(10):1303-7. Epub 2007 May 15.PMID: 17504847 [PubMed - indexed for MEDLINE]Related articles

An analysis of the CFH Y402H genotype in AMD patients and controls from the UK, and response to PDT treatment.

Goverdhan SV, Hannan S, Newsom RB, Luff AJ, Griffiths H, Lotery AJ.

Eye (Lond). 2008 Jun;22(6):849-54. Epub 2007 Apr 27.PMID: 17464302 [PubMed - indexed for MEDLINE]Related articles

Ranibizumab (Lucentis) versus bevacizumab (Avastin): modelling cost effectiveness.

Raftery J, Clegg A, Jones J, Tan SC, Lotery A.

Br J Ophthalmol. 2007 Sep;91(9):1244-6. Epub 2007 Apr 12.PMID: 17431015 [PubMed - indexed for MEDLINE]Related articles

The cheaper drug, bevacizumab, should be referred to NICE.

Raftery JP, Lotery A.

BMJ. 2007 Feb 24;334(7590):381-2. No abstract available. PMID: 17322218 [PubMed - indexed for MEDLINE]Related articles

Fine-scale linkage disequilibrium mapping of age-related macular degeneration in the complement factor H gene region.

Ennis S, Goverdhan S, Cree A, Hoh J, Collins A, Lotery A.

Br J Ophthalmol. 2007 Jul;91(7):966-70. Epub 2007 Feb 21.PMID: 17314151 [PubMed - indexed for MEDLINE]Related articles

Fine mapping of the X-linked recessive congenital idiopathic nystagmus locus at Xq24-q26.3.

Self JE, Ennis S, Collins A, Shawkat F, Harris CM, Mackey DA, Hodgkins PR, Temple IK, Chen X, Lotery AJ.

Mol Vis. 2006 Oct 18;12:1211-6.PMID: 17102799 [PubMed - indexed for MEDLINE]Related articlesFree article

Syphilitic acute posterior placoid chorioretinitis in nonimmuno-compromised patients.

Joseph A, Rogers S, Browning A, Hall N, Barber C, Lotery A, Foley E, Amoaku WM.

Eye (Lond). 2007 Aug;21(8):1114-9. Epub 2006 Oct 6.PMID: 17024225 [PubMed - indexed for MEDLINE]Related articles

Bevacizumab: a new way of doing business?

Canning C, Lotery A.

Eye (Lond). 2006 Sep;20(9):985-7. Epub 2006 Jul 21. Review.PMID: 16858443 [PubMed - indexed for MEDLINE]Related articles

Complement factor H Y402H gene polymorphism in coronary artery disease and atherosclerosis.

Goverdhan SV, Lotery AJ, Cree AJ, Ye S.

Atherosclerosis. 2006 Sep;188(1):213-4. Epub 2006 May 30. No abstract available. PMID: 16730735 [PubMed - indexed for MEDLINE]Related articles

The molecular genetics of congenital idiopathic nystagmus.

Self J, Lotery A.

Semin Ophthalmol. 2006 Apr-Jun;21(2):87-90. Review.PMID: 16702075 [PubMed - indexed for MEDLINE]Related articles

Case of Stargardt disease caused by uniparental isodisomy.

Fingert JH, Eliason DA, Phillips NC, Lotery AJ, Sheffield VC, Stone EM.

Arch Ophthalmol. 2006 May;124(5):744-5. No abstract available. PMID: 16682602 [PubMed - indexed for MEDLINE]Related articles

Reduced secretion of fibulin 5 in age-related macular degeneration and cutis laxa.

Lotery AJ, Baas D, Ridley C, Jones RP, Klaver CC, Stone E, Nakamura T, Luff A, Griffiths H, Wang T, Bergen AA, Trump D.

Hum Mutat. 2006 Jun;27(6):568-74.PMID: 16652333 [PubMed - indexed for MEDLINE]Related articlesFree article

Report of a novel lobular chorioretinal dystrophy.

Moradi P, Lotery A.

Eye (Lond). 2006 Dec;20(12):1390-2. Epub 2006 Feb 3. No abstract available. PMID: 16456598 [PubMed - indexed for MEDLINE]Related articles

HLA and eye disease: a synopsis.

Goverdhan SV, Lotery AJ, Howell WM.

Int J Immunogenet. 2005 Dec;32(6):333-42. Review.PMID: 16313296 [PubMed - indexed for MEDLINE]Related articles

Macular degeneration associated with a novel Treacher Collins tcof1 mutation and evaluation of this mutation in age related macular degeneration.

Goverdhan SV, Temple IK, Self J, Lotery AJ, Dixon MJ, Evans AR.

Br J Ophthalmol. 2005 Aug;89(8):1063-4. No abstract available. PMID: 16024866 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of HLA class I and class II polymorphisms with age-related macular degeneration.

Goverdhan SV, Howell MW, Mullins RF, Osmond C, Hodgkins PR, Self J, Avery K, Lotery AJ.

Invest Ophthalmol Vis Sci. 2005 May;46(5):1726-34.PMID: 15851575 [PubMed - indexed for MEDLINE]Related articlesFree article

Glutamate excitotoxicity in glaucoma: truth or fiction?

Lotery AJ.

Eye (Lond). 2005 Apr;19(4):369-70. No abstract available. PMID: 15806116 [PubMed - indexed for MEDLINE]Related articles

Radiotherapy for age-related macular degeneration: no more pilot studies please.

Goverdhan SV, Gibbs FA, Lotery AJ.

Eye (Lond). 2005 Nov;19(11):1137-41. Review. No abstract available. PMID: 15543181 [PubMed - indexed for MEDLINE]Related articles

Missense variations in the fibulin 5 gene and age-related macular degeneration.

Stone EM, Braun TA, Russell SR, Kuehn MH, Lotery AJ, Moore PA, Eastman CG, Casavant TL, Sheffield VC.

N Engl J Med. 2004 Jul 22;351(4):346-53.PMID: 15269314 [PubMed - indexed for MEDLINE]Related articlesFree article

Adeno-associated virus type 5: transduction efficiency and cell-type specificity in the primate retina.

Lotery AJ, Yang GS, Mullins RF, Russell SR, Schmidt M, Stone EM, Lindbloom JD, Chiorini JA, Kotin RM, Davidson BL.

Hum Gene Ther. 2003 Nov 20;14(17):1663-71.PMID: 14633408 [PubMed - indexed for MEDLINE]Related articles

Characterization of rabbit myocilin: Implications for human myocilin glycosylation and signal peptide usage.

Shepard AR, Jacobson N, Sui R, Steely HT, Lotery AJ, Stone EM, Clark AF.

BMC Genet. 2003 Apr 2;4:5.PMID: 12697062 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetics update of macular diseases.

Chung M, Lotery AJ.

Ophthalmol Clin North Am. 2002 Dec;15(4):459-65. Review.PMID: 12515078 [PubMed - indexed for MEDLINE]Related articles

Electroretinographic abnormalities in parents of patients with Leber congenital amaurosis who have heterozygous GUCY2D mutations.

Koenekoop RK, Fishman GA, Iannaccone A, Ezzeldin H, Ciccarelli ML, Baldi A, Sunness JS, Lotery AJ, Jablonski MM, Pittler SJ, Maumenee I.

Arch Ophthalmol. 2002 Oct;120(10):1325-30.PMID: 12365911 [PubMed - indexed for MEDLINE]Related articles

Retinal pathology and function in a Cln3 knockout mouse model of juvenile Neuronal Ceroid Lipofuscinosis (batten disease).

Seigel GM, Lotery A, Kummer A, Bernard DJ, Greene ND, Turmaine M, Derksen T, Nussbaum RL, Davidson B, Wagner J, Mitchison HM.

Mol Cell Neurosci. 2002 Apr;19(4):515-27.PMID: 11988019 [PubMed - indexed for MEDLINE]Related articles

Gene transfer to the nonhuman primate retina with recombinant feline immunodeficiency virus vectors.

Lotery AJ, Derksen TA, Russell SR, Mullins RF, Sauter S, Affatigato LM, Stone EM, Davidson BL.

Hum Gene Ther. 2002 Apr 10;13(6):689-96.PMID: 11936968 [PubMed - indexed for MEDLINE]Related articles