PubMed

Genetic Factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) Are Predictor Variables for Warfarin Response in Very Elderly, Frail Inpatients.

Pautas E, Moreau C, Gouin-Thibault I, Golmard JL, Mahé I, Legendre C, Taillandier-Hériche E, Durand-Gasselin B, Houllier AM, Verrier P, Beaune P, Loriot MA, Siguret V.

Clin Pharmacol Ther. 2009 Sep 30. [Epub ahead of print]PMID: 19794411 [PubMed - as supplied by publisher]Related articles

Lambert-Eaton myasthenic syndrome revealing an abdominal neuroblastoma.

de Buys Roessingh AS, Loriot MH, Wiesenauer C, Lallier M.

J Pediatr Surg. 2009 Aug;44(8):E5-7.PMID: 19635290 [PubMed - indexed for MEDLINE]Related articles

[Chloroquine cardiotoxicity in long-term lupus therapy in two patients.]

Saussine A, Loriot MA, Picard C, Lecerf V, Landry J, Scheer I, Voicu S, Leenhardt A, Ducrocq G, Maubec E, Crickx B.

Ann Dermatol Venereol. 2009 Jun-Jul;136(6-7):530-5. Epub 2009 Jun 2. French. PMID: 19560616 [PubMed - indexed for MEDLINE]Related articles

Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function.

Dutheil F, Dauchy S, Diry M, Sazdovitch V, Cloarec O, Mellottée L, Bièche I, Ingelman-Sundberg M, Flinois JP, de Waziers I, Beaune P, Declèves X, Duyckaerts C, Loriot MA.

Drug Metab Dispos. 2009 Jul;37(7):1528-38. Epub 2009 Apr 9.PMID: 19359404 [PubMed - indexed for MEDLINE]Related articles

Voriconazole pharmacokinetic variability in cystic fibrosis lung transplant patients.

Berge M, Guillemain R, Boussaud V, Pham MH, Chevalier P, Batisse A, Amrein C, Dannaoui E, Loriot MA, Lillo-Le Louet A, Billaud EM.

Transpl Infect Dis. 2009 Jun;11(3):211-9. Epub 2009 Mar 17.PMID: 19302272 [PubMed - indexed for MEDLINE]Related articles

VKORC1 haplotypes and long-term renal allograft survival.

Pallet N, Loriot MA, Anglicheau D, Legendre C, Beaune P, Thervet E.

Transplantation. 2009 Mar 27;87(6):942. No abstract available. PMID: 19300200 [PubMed - indexed for MEDLINE]Related articles

[The biological point of view on pharmacogenetics of anticancer agents in colorectal cancer]

Laurent-Puig P, Lièvre A, Ducreux M, Loriot MA.

Bull Cancer. 2008 Oct;95(10):935-42. French. PMID: 19004723 [PubMed - indexed for MEDLINE]Related articles

Glutathione S-transferases related to P. aeruginosa lung infection in cystic fibrosis children: preliminary study.

Feuillet-Fieux MN, Nguyen-Khoa T, Loriot MA, Kelly M, de Villartay P, Sermet I, Verrier P, Bonnefont JP, Beaune P, Lenoir G, Lacour B.

Clin Biochem. 2009 Jan;42(1-2):57-63. Epub 2008 Oct 17.PMID: 18976645 [PubMed - indexed for MEDLINE]Related articles

Characterisation of novel defective thiopurine S-methyltransferase allelic variants.

Garat A, Cauffiez C, Renault N, Lo-Guidice JM, Allorge D, Chevalier D, Houdret N, Chavatte P, Loriot MA, Gala JL, Broly F.

Biochem Pharmacol. 2008 Aug 1;76(3):404-15. Epub 2008 May 18.PMID: 18602085 [PubMed - indexed for MEDLINE]Related articles

Multiple genetic alterations in vitamin K epoxide reductase complex subunit 1 gene (VKORC1) can explain the high dose requirement during oral anticoagulation in humans.

Bodin L, Perdu J, Diry M, Horellou MH, Loriot MA.

J Thromb Haemost. 2008 Aug;6(8):1436-9. Epub 2008 Jun 4. No abstract available. PMID: 18532998 [PubMed - indexed for MEDLINE]Related articles

No clear link between VKORC1 genetic polymorphism and the risk of venous thrombosis or peripheral arterial disease.

Smadja DM, Loriot MA, Hindorff LA, Mellottee L, Gaussem P, Emmerich J.

Thromb Haemost. 2008 May;99(5):970-2. No abstract available. PMID: 18449434 [PubMed - indexed for MEDLINE]Related articles

Overanticoagulation with coumarin and cutaneous azole therapy.

Alexandra JF, Pautas E, Gouin-Thibault I, Siguret V, Loriot MA.

Ann Intern Med. 2008 Apr 15;148(8):633-5. No abstract available. Erratum in: Ann Intern Med. 2008 May 20;148(10):795. Gouin-Thibault, Isabelle [added]; Siguret, Virginie [added]; Loriot, Marie-Anne [added]. PMID: 18413637 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocellular carcinoma and occupation in men: a case-control study.

Ferrand JF, Cénée S, Laurent-Puig P, Loriot MA, Trinchet JC, Degos F, Bronovicky JP, Pelletier G, Stücker I.

J Occup Environ Med. 2008 Feb;50(2):212-20.PMID: 18301178 [PubMed - indexed for MEDLINE]Related articles

Minocycline-induced DRESS: evidence for accumulation of the culprit drug.

Maubec E, Wolkenstein P, Loriot MA, Wechsler J, Mulot C, Beaune P, Revuz J, Roujeau JC.

Dermatology. 2008;216(3):200-4. Epub 2008 Jan 9.PMID: 18182810 [PubMed - indexed for MEDLINE]Related articles

[Molecular pharmacogenetics in hospital laboratories in France: current data and future prospects]

Allorge D, Beaune PH, Becquemont L, Bessard G, Bezieau S, Boisdron-Celle M, Boyer JC, Broly F, Dhaneens CM, Fonrose X, Gagnieu MC, Gamelin E, Gozé C, Jacqz-Aigrain E, Loric S, Loriot MA, Marquet P, Morel A, Namour B, Paintaud G, Peoc'h K, Picard N, Watier H, Verstuyft C.

Ann Pharm Fr. 2007 Nov;65(6):371-81. Review. French. PMID: 18079669 [PubMed - indexed for MEDLINE]Related articles

UDP-glucuronosyltransferase UGT1A7 genetic polymorphisms in hepatocellular carcinoma: a differential impact according to seropositivity of HBV or HCV markers?

Stücker I, Loriot MA, N'koutchou G, Cénée S, Bodin L, Mulot C, Gelu-Simeon M, Pelletier L, Bronowicki JP, Degos F, Beaune P, Laurent-Puig P, Hémon D, Trinchet JC, Pelletier G.

BMC Cancer. 2007 Nov 19;7:214.PMID: 18021430 [PubMed - indexed for MEDLINE]Related articlesFree article

Xenobiotic metabolizing enzymes in the central nervous system: Contribution of cytochrome P450 enzymes in normal and pathological human brain.

Dutheil F, Beaune P, Loriot MA.

Biochimie. 2008 Mar;90(3):426-36. Epub 2007 Oct 22. Review.PMID: 17997991 [PubMed - indexed for MEDLINE]Related articles

Acetaminophen reinforces descending inhibitory pain pathways.

Pickering G, Estève V, Loriot MA, Eschalier A, Dubray C.

Clin Pharmacol Ther. 2008 Jul;84(1):47-51. Epub 2007 Oct 24.PMID: 17957182 [PubMed - indexed for MEDLINE]Related articles

[Pharmacogenetics of oral anticoagulants: individualized drug treatment for more efficacy and safety]

Loriot MA, Beaune P.

Rev Prat. 2007 Jun 30;57(12):1281-6. Review. French. PMID: 17717937 [PubMed - indexed for MEDLINE]Related articles

Multidrug resistance gene-1 polymorphisms and resistance to cyclosporine A in patients with steroid resistant ulcerative colitis.

Daniel F, Loriot MA, Seksik P, Cosnes J, Gornet JM, Lémann M, Fein F, Vernier-Massouille G, De Vos M, Boureille A, Treton X, Flourié B, Roblin X, Louis E, Zerbib F, Beaune P, Marteau P.

Inflamm Bowel Dis. 2007 Jan;13(1):19-23.PMID: 17206635 [PubMed - indexed for MEDLINE]Related articlesFree article

[Vitamin K epoxide reductase: Fresh blood for oral anticoagulant therapies]

Loriot MA, Beaune P.

Rev Med Interne. 2006 Dec;27(12):979-82. Epub 2006 Oct 11. Review. French. PMID: 17070618 [PubMed - indexed for MEDLINE]Related articles

Glutathione S-transferase P1 polymorphism (Ile105Val) predicts cumulative neuropathy in patients receiving oxaliplatin-based chemotherapy.

Lecomte T, Landi B, Beaune P, Laurent-Puig P, Loriot MA.

Clin Cancer Res. 2006 May 15;12(10):3050-6.PMID: 16707601 [PubMed - indexed for MEDLINE]Related articlesFree article

Analgesic effect of acetaminophen in humans: first evidence of a central serotonergic mechanism.

Pickering G, Loriot MA, Libert F, Eschalier A, Beaune P, Dubray C.

Clin Pharmacol Ther. 2006 Apr;79(4):371-8.PMID: 16580905 [PubMed - indexed for MEDLINE]Related articles

Interaction between tacrolimus and omeprazole in a pediatric liver transplant recipient.

Moreau C, Debray D, Loriot MA, Taburet AM, Furlan V.

Transplantation. 2006 Feb 15;81(3):487-8. No abstract available. Erratum in: Transplantation. 2006 Nov 27;82(10):1382. PMID: 16477241 [PubMed - indexed for MEDLINE]Related articles

Association analysis of drug metabolizing enzyme gene polymorphisms in AIDS patients with cutaneous reactions to sulfonamides.

Wolkenstein P, Loriot MA, Flahault A, Cadilhac M, Caumes E, Eliaszewicz M, Beaune P, Roujeau JC, Chosidow O; Epitox Group.

J Invest Dermatol. 2005 Nov;125(5):1080-2. No abstract available. PMID: 16297214 [PubMed - indexed for MEDLINE]Related articlesFree article

Myeloperoxidase genetic polymorphisms modulate human neutrophil enzyme activity: genetic determinants for atherosclerosis?

Chevrier I, Tregouet DA, Massonnet-Castel S, Beaune P, Loriot MA.

Atherosclerosis. 2006 Sep;188(1):150-4. Epub 2005 Nov 10.PMID: 16289072 [PubMed - indexed for MEDLINE]Related articles

Childhood leukaemia, polymorphisms of metabolism enzyme genes, and interactions with maternal tobacco, coffee and alcohol consumption during pregnancy.

Clavel J, Bellec S, Rebouissou S, Ménégaux F, Feunteun J, Bonaïti-Pellié C, Baruchel A, Kebaili K, Lambilliotte A, Leverger G, Sommelet D, Lescoeur B, Beaune P, Hémon D, Loriot MA.

Eur J Cancer Prev. 2005 Dec;14(6):531-40.PMID: 16284498 [PubMed - indexed for MEDLINE]Related articles

Collection of human genomic DNA from buccal cells for genetics studies: comparison between cytobrush, mouthwash, and treated card.

Mulot C, Stücker I, Clavel J, Beaune P, Loriot MA.

J Biomed Biotechnol. 2005;2005(3):291-6.PMID: 16192688 [PubMed]Related articlesFree article

Determination of cytochrome P450 2D6 (CYP2D6) gene copy number by real-time quantitative PCR.

Bodin L, Beaune PH, Loriot MA.

J Biomed Biotechnol. 2005;2005(3):248-53.PMID: 16192683 [PubMed]Related articlesFree article

A vitamin K epoxide reductase complex subunit-1 (VKORC1) mutation in a patient with vitamin K antagonist resistance.

Bodin L, Horellou MH, Flaujac C, Loriot MA, Samama MM.

J Thromb Haemost. 2005 Jul;3(7):1533-5. No abstract available. PMID: 15978113 [PubMed - indexed for MEDLINE]Related articles

Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity.

Bodin L, Verstuyft C, Tregouet DA, Robert A, Dubert L, Funck-Brentano C, Jaillon P, Beaune P, Laurent-Puig P, Becquemont L, Loriot MA.

Blood. 2005 Jul 1;106(1):135-40. Epub 2005 Mar 24.PMID: 15790782 [PubMed - indexed for MEDLINE]Related articlesFree article

[Pharmacogenetics of anticancer drugs.]

de Chaisemartin L, Loriot MA.

Pathol Biol (Paris). 2005 Mar;53(2):116-24. Review. French. PMID: 15708657 [PubMed - indexed for MEDLINE]Related articles

TEGDMA modulates glutathione transferase P1 activity in gingival fibroblasts.

Lefeuvre M, Bourd K, Loriot MA, Goldberg M, Beaune P, Périanin A, Stanislawski L.

J Dent Res. 2004 Dec;83(12):914-9.PMID: 15557397 [PubMed - indexed for MEDLINE]Related articles

Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy.

Lecomte T, Ferraz JM, Zinzindohoué F, Loriot MA, Tregouet DA, Landi B, Berger A, Cugnenc PH, Jian R, Beaune P, Laurent-Puig P.

Clin Cancer Res. 2004 Sep 1;10(17):5880-8.PMID: 15355920 [PubMed - indexed for MEDLINE]Related articlesFree article

[Pharmacogenetics or the promise of a personalized medicine: variability in drug metabolism and transport]

Allorge D, Loriot MA.

Ann Biol Clin (Paris). 2004 Sep-Oct;62(5):499-511. Review. French. PMID: 15355800 [PubMed - indexed for MEDLINE]Related articlesFree article

[Pharmacogenomics: the link between genes and response to drugs]

Loriot MA, Beaune P.

Med Sci (Paris). 2004 Jun-Jul;20(6-7):634-6. French. No abstract available. PMID: 15329810 [PubMed - indexed for MEDLINE]Related articlesFree article

Single nucleotide polymorphisms in MMP1 and MMP3 gene promoters as risk factor in head and neck squamous cell carcinoma.

Zinzindohoué F, Blons H, Hans S, Loriot MA, Houllier AM, Brasnu D, Laccourreye O, Tregouet DA, Stucker I, Laurent-Puig P.

Anticancer Res. 2004 May-Jun;24(3b):2021-6.PMID: 15274394 [PubMed - indexed for MEDLINE]Related articles

Pharmacogenetics of acenocoumarol pharmacodynamics.

Morin S, Bodin L, Loriot MA, Thijssen HH, Robert A, Strabach S, Verstuyft C, Tregouet DA, Dubert L, Laurent-Puig P, Funck-Brentano C, Jaillon P, Beaune PH, Becquemont L.

Clin Pharmacol Ther. 2004 May;75(5):403-14.PMID: 15116053 [PubMed - indexed for MEDLINE]Related articles

Impact of GSTT1, GSTM1, GSTP1 and NAT2 genotypes on KRAS2 and TP53 gene mutations in colorectal cancer.

Ferraz JM, Zinzindohoué F, Lecomte T, Cugnenc PH, Loriot MA, Beaune P, Stücker I, Berger A, Laurent-Puig P.

Int J Cancer. 2004 Jun 10;110(2):183-7.PMID: 15069679 [PubMed - indexed for MEDLINE]Related articles

Myeloperoxidase: new polymorphisms and relation with lung cancer risk.

Chevrier I, Stücker I, Houllier AM, Cenée S, Beaune P, Laurent-Puig P, Loriot MA.

Pharmacogenetics. 2003 Dec;13(12):729-39.PMID: 14646692 [PubMed - indexed for MEDLINE]Related articles

[A new, rapid and robust genotyping method for CYP2C9 and MDR1]

Verstuyft C, Morin S, Yang J, Loriot MA, Barbu V, Kerb R, Brinkmann U, Beaune P, Jaillon P, Becquemont L.

Ann Biol Clin (Paris). 2003 May-Jun;61(3):305-9. French. PMID: 12805007 [PubMed - indexed for MEDLINE]Related articlesFree article

Failure of prenatal diagnosis of diploid-triploid mosaicism after amniocentesis.

Flori E, Doray B, Rudolf G, Favre R, Girard-Lemaire F, Schluth C, Zix-Kieffer I, Flori J, Loriot M, Schmitt E, Rumpler Y.

Clin Genet. 2003 Apr;63(4):328-31. No abstract available. PMID: 12702170 [PubMed - indexed for MEDLINE]Related articles

Genetic and environmental risk factors for oral anticoagulant overdose.

Verstuyft C, Robert A, Morin S, Loriot MA, Flahault A, Beaune P, Funck-Brentano C, Jaillon P, Becquemont L.

Eur J Clin Pharmacol. 2003 Mar;58(11):739-45. Epub 2003 Feb 18.PMID: 12634980 [PubMed - indexed for MEDLINE]Related articles

Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility.

Stücker I, Hirvonen A, de Waziers I, Cabelguenne A, Mitrunen K, Cénée S, Koum-Besson E, Hémon D, Beaune P, Loriot MA.

Carcinogenesis. 2002 Sep;23(9):1475-81.PMID: 12189190 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiopurine methyltransferase activity: new conditions for reversed-phase high-performance liquid chromatographic assay without extraction and genotypic-phenotypic correlation.

Anglicheau D, Sanquer S, Loriot MA, Beaune P, Thervet E.

J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Jun 25;773(2):119-27.PMID: 12031837 [PubMed - indexed for MEDLINE]Related articles

Early acenocoumarol overanticoagulation among cytochrome P450 2C9 poor metabolizers.

Verstuyft C, Morin S, Robert A, Loriot MA, Beaune P, Jaillon P, Becquemont L.

Pharmacogenetics. 2001 Nov;11(8):735-7.PMID: 11692083 [PubMed - indexed for MEDLINE]Related articles

Glutathione-associated enzymes in head and neck squamous cell carcinoma and response to cisplatin-based neoadjuvant chemotherapy.

Cabelguenne A, Loriot MA, Stucker I, Blons H, Koum-Besson E, Brasnu D, Beaune P, Laccourreye O, Laurent-Puig P, De Waziers I.

Int J Cancer. 2001 Sep 1;93(5):725-30.PMID: 11477586 [PubMed - indexed for MEDLINE]Related articles

Is diclofenac a valuable CYP2C9 probe in humans?

Morin S, Loriot MA, Poirier JM, Tenneze L, Beaune PH, Funck-Brentano C, Jaillon P, Becquemont L.

Eur J Clin Pharmacol. 2001 Jan-Feb;56(11):793-7.PMID: 11294368 [PubMed - indexed for MEDLINE]Related articles

Genetic polymorphisms of cytochrome P450 2A6 in a case-control study on lung cancer in a French population.

Loriot MA, Rebuissou S, Oscarson M, Cenée S, Miyamoto M, Ariyoshi N, Kamataki T, Hémon D, Beaune P, Stücker I.

Pharmacogenetics. 2001 Feb;11(1):39-44.PMID: 11207029 [PubMed - indexed for MEDLINE]Related articles

Prospective evaluation of detoxification pathways as markers of cutaneous adverse reactions to sulphonamides in AIDS.

Wolkenstein P, Loriot MA, Aractingi S, Cabelguenne A, Beaune P, Chosidow O.

Pharmacogenetics. 2000 Dec;10(9):821-8.PMID: 11191886 [PubMed - indexed for MEDLINE]Related articles