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    Results: 1 to 50 of 72

    1.

    Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome.

    Abarrategui-Garrido C, Martínez-Barricarte R, López-Trascasa M, de Córdoba SR, Sánchez-Corral P.

    Blood. 2009 Nov 5;114(19):4261-71. Epub 2009 Sep 10.PMID: 19745068 [PubMed - indexed for MEDLINE]Related articles

    2.

    Successful renal transplantation in a patient with atypical hemolytic uremic syndrome carrying mutations in both factor I and MCP.

    Cruzado JM, de Córdoba SR, Melilli E, Bestard O, Rama I, Sánchez-Corral P, López-Trascasa M, Navarro I, Torras J, Gomà M, Grinyó JM.

    Am J Transplant. 2009 Jun;9(6):1477-83. Epub 2009 May 20.PMID: 19459807 [PubMed - indexed for MEDLINE]Related articles

    3.

    Molecular characterization of three new mutations causing C5 deficiency in two non-related families.

    López-Lera A, Garrido S, de la Cruz RM, Fontán G, López-Trascasa M.

    Mol Immunol. 2009 Jul;46(11-12):2340-7. Epub 2009 May 2.PMID: 19414197 [PubMed - indexed for MEDLINE]Related articles

    4.

    Association of anti-C1 inhibitor and anti-protein S antibodies in a patient with primary antiphospholipid syndrome.

    López-Trascasa M, Gil-Aguado A, Capozzi A, Sorice M.

    Lupus. 2009 Feb;18(2):182-3. No abstract available. PMID: 19151124 [PubMed - indexed for MEDLINE]Related articles

    5.

    Functional C1-inhibitor diagnostics in hereditary angioedema: assay evaluation and recommendations.

    Wagenaar-Bos IG, Drouet C, Aygören-Pursun E, Bork K, Bucher C, Bygum A, Farkas H, Fust G, Gregorek H, Hack CE, Hickey A, Joller-Jemelka HI, Kapusta M, Kreuz W, Longhurst H, Lopez-Trascasa M, Madalinski K, Naskalski J, Nieuwenhuys E, Ponard D, Truedsson L, Varga L, Nielsen EW, Wagner E, Zingale L, Cicardi M, van Ham SM.

    J Immunol Methods. 2008 Sep 30;338(1-2):14-20. Epub 2008 Jul 23.PMID: 18655790 [PubMed - indexed for MEDLINE]Related articles

    6.

    Mutations in proteins of the alternative pathway of complement and the pathogenesis of atypical hemolytic uremic syndrome.

    Abarrategui-Garrido C, Melgosa M, Peña-Carrión A, de Jorge EG, de Córdoba SR, López-Trascasa M, Sánchez-Corral P.

    Am J Kidney Dis. 2008 Jul;52(1):171-80. Epub 2008 Apr 18.PMID: 18423815 [PubMed - indexed for MEDLINE]Related articles

    7.

    Molecular characterization of Complement Factor I deficiency in two Spanish families.

    Ponce-Castro IM, González-Rubio C, Delgado-Cerviño EM, Abarrategui-Garrido C, Fontán G, Sánchez-Corral P, López-Trascasa M.

    Mol Immunol. 2008 May;45(10):2764-71. Epub 2008 Mar 28.PMID: 18374984 [PubMed - indexed for MEDLINE]Related articles

    8.

    Successful use of rituximab in acquired C1 inhibitor deficiency secondary to Sjogren's syndrome.

    Sánchez-Cano D, Callejas-Rubio JL, Lara-Jiménez MA, López-Trascasa M, Circadi M, Ortego-Centeno N.

    Lupus. 2008;17(3):228-9. No abstract available. PMID: 18372365 [PubMed - indexed for MEDLINE]Related articles

    9.

    Antinucleosome antibodies as a marker of active proliferative lupus nephritis.

    Bigler C, Lopez-Trascasa M, Potlukova E, Moll S, Danner D, Schaller M, Trendelenburg M.

    Am J Kidney Dis. 2008 Apr;51(4):624-9.PMID: 18371538 [PubMed - indexed for MEDLINE]Related articles

    10.

    Metallopeptidase activities in hereditary angioedema: effect of androgen prophylaxis on plasma aminopeptidase P.

    Drouet C, Désormeaux A, Robillard J, Ponard D, Bouillet L, Martin L, Kanny G, Moneret-Vautrin DA, Bosson JL, Quesada JL, López-Trascasa M, Adam A.

    J Allergy Clin Immunol. 2008 Feb;121(2):429-33. Epub 2007 Dec 26.PMID: 18158172 [PubMed - indexed for MEDLINE]Related articles

    11.

    HIV-1 induced generation of C5a attracts immature dendriticcells and promotes infection of autologous T cells.

    Soederholm A, Bánki Z, Wilflingseder D, Gassner C, Zwirner J, López-Trascasa M, Falkensammer B, Dierich MP, Stoiber H.

    Eur J Immunol. 2007 Aug;37(8):2156-63.PMID: 17595678 [PubMed - indexed for MEDLINE]Related articles

    12.

    Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome.

    Goicoechea de Jorge E, Harris CL, Esparza-Gordillo J, Carreras L, Arranz EA, Garrido CA, López-Trascasa M, Sánchez-Corral P, Morgan BP, Rodríguez de Córdoba S.

    Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):240-5. Epub 2006 Dec 20. Erratum in: Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10749. PMID: 17182750 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    First case of homozygous C1 inhibitor deficiency.

    Blanch A, Roche O, Urrutia I, Gamboa P, Fontán G, López-Trascasa M.

    J Allergy Clin Immunol. 2006 Dec;118(6):1330-5. Epub 2006 Sep 18. Erratum in: J Allergy Clin Immunol. 2007 Mar;119(3):745. PMID: 17137866 [PubMed - indexed for MEDLINE]Related articles

    14.

    The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models.

    Saunders RE, Abarrategui-Garrido C, Frémeaux-Bacchi V, Goicoechea de Jorge E, Goodship TH, López Trascasa M, Noris M, Ponce Castro IM, Remuzzi G, Rodríguez de Córdoba S, Sánchez-Corral P, Skerka C, Zipfel PF, Perkins SJ.

    Hum Mutat. 2007 Mar;28(3):222-34.PMID: 17089378 [PubMed - indexed for MEDLINE]Related articles

    15.

    High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis.

    Trendelenburg M, Lopez-Trascasa M, Potlukova E, Moll S, Regenass S, Frémeaux-Bacchi V, Martinez-Ara J, Jancova E, Picazo ML, Honsova E, Tesar V, Sadallah S, Schifferli J.

    Nephrol Dial Transplant. 2006 Nov;21(11):3115-21. Epub 2006 Jul 28.PMID: 16877491 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Molecular defects of the C7 gene in two patients with complement C7 deficiency.

    Barroso S, Rieubland C, José álvarez A, López-Trascasa M, Bart PA, Núñez-Roldán A, Sánchez B.

    Immunology. 2006 Jun;118(2):257-60.PMID: 16771861 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree.

    Esparza-Gordillo J, Jorge EG, Garrido CA, Carreras L, López-Trascasa M, Sánchez-Corral P, de Córdoba SR.

    Mol Immunol. 2006 Apr;43(11):1769-75. Epub 2006 Jan 18.PMID: 16386793 [PubMed - indexed for MEDLINE]Related articles

    18.

    Hereditary angioedema: the mutation spectrum of SERPING1/C1NH in a large Spanish cohort.

    Roche O, Blanch A, Duponchel C, Fontán G, Tosi M, López-Trascasa M.

    Hum Mutat. 2005 Aug;26(2):135-44.PMID: 15971231 [PubMed - indexed for MEDLINE]Related articles

    19.

    Hereditary angioedema due to C1 inhibitor deficiency: patient registry and approach to the prevalence in Spain.

    Roche O, Blanch A, Caballero T, Sastre N, Callejo D, López-Trascasa M.

    Ann Allergy Asthma Immunol. 2005 Apr;94(4):498-503.PMID: 15875532 [PubMed - indexed for MEDLINE]Related articles

    20.

    Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32.

    Esparza-Gordillo J, Goicoechea de Jorge E, Buil A, Carreras Berges L, López-Trascasa M, Sánchez-Corral P, Rodríguez de Córdoba S.

    Hum Mol Genet. 2005 Mar 1;14(5):703-12. Epub 2005 Jan 20. Erratum in: Hum Mol Genet. 2005 Apr 15;14(8):1107. PMID: 15661753 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Complement component C7 deficiency in two Spanish families.

    Barroso S, Sánchez B, Alvarez AJ, López-Trascasa M, Lanuza A, Luque R, Wichmann I, Núñez-Roldán A.

    Immunology. 2004 Dec;113(4):518-23.PMID: 15554930 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    C5 complement deficiency in a Spanish family. Molecular characterization of the double mutation responsible for the defect.

    Delgado-Cerviño E, Fontán G, López-Trascasa M.

    Mol Immunol. 2005 Jan;42(1):105-11.PMID: 15488949 [PubMed - indexed for MEDLINE]Related articles

    23.

    [Hereditary angioedema of delayed onset]

    López Trascasa M, Blanch A, Roche O, Ferreira A.

    An Med Interna. 2004 Sep;21(9):468-9. Spanish. No abstract available. PMID: 15476433 [PubMed - indexed for MEDLINE]Related articles

    24.

    Hereditary and acquired angioedema: problems and progress: proceedings of the third C1 esterase inhibitor deficiency workshop and beyond.

    Agostoni A, Aygören-Pürsün E, Binkley KE, Blanch A, Bork K, Bouillet L, Bucher C, Castaldo AJ, Cicardi M, Davis AE, De Carolis C, Drouet C, Duponchel C, Farkas H, Fáy K, Fekete B, Fischer B, Fontana L, Füst G, Giacomelli R, Gröner A, Hack CE, Harmat G, Jakenfelds J, Juers M, Kalmár L, Kaposi PN, Karádi I, Kitzinger A, Kollár T, Kreuz W, Lakatos P, Longhurst HJ, Lopez-Trascasa M, Martinez-Saguer I, Monnier N, Nagy I, Németh E, Nielsen EW, Nuijens JH, O'grady C, Pappalardo E, Penna V, Perricone C, Perricone R, Rauch U, Roche O, Rusicke E, Späth PJ, Szendei G, Takács E, Tordai A, Truedsson L, Varga L, Visy B, Williams K, Zanichelli A, Zingale L.

    J Allergy Clin Immunol. 2004 Sep;114(3 Suppl):S51-131.PMID: 15356535 [PubMed - indexed for MEDLINE]Related articles

    25.

    The human complement factor H: functional roles, genetic variations and disease associations.

    Rodríguez de Córdoba S, Esparza-Gordillo J, Goicoechea de Jorge E, Lopez-Trascasa M, Sánchez-Corral P.

    Mol Immunol. 2004 Jun;41(4):355-67. Review.PMID: 15163532 [PubMed - indexed for MEDLINE]Related articles

    26.

    Functional analysis in serum from atypical Hemolytic Uremic Syndrome patients reveals impaired protection of host cells associated with mutations in factor H.

    Sánchez-Corral P, González-Rubio C, Rodríguez de Córdoba S, López-Trascasa M.

    Mol Immunol. 2004 May;41(1):81-4.PMID: 15140578 [PubMed - indexed for MEDLINE]Related articles

    27.

    [Genetic factors in the haemolytic uremic syndrome. Diagnostic and therapeutic implications]

    Rodríguez de Córdoba S, Peña A, Rivera F, López Trascasa M, Sánchez-Corral P.

    Nefrologia. 2004;24(1):9-11. Spanish. No abstract available. PMID: 15083952 [PubMed - indexed for MEDLINE]Related articles

    28.

    Complement component C7 deficiency in a Spanish family.

    Vázquez-Bermúdez MF, Barroso S, Walter K, Alvarez AJ, Alarcón A, López-Trascasa M, Wichmann I, Aguilar F, Núñez-Roldán A, Sánchez B.

    Clin Exp Immunol. 2003 Aug;133(2):240-6.PMID: 12869030 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    Autoantibodies against complement receptor 1 (CD35) in SLE, liver cirrhosis and HIV-infected patients.

    Sadallah S, Hess C, Trendelenburg M, Vedeler C, Lopez-Trascasa M, Schifferli JA.

    Clin Exp Immunol. 2003 Jan;131(1):174-81.PMID: 12519402 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    The mechanism of loss of CR1 during maturation of erythrocytes is different between factor I deficient patients and healthy donors.

    Miot S, Marfurt J, Lach-Trifilieff E, González-Rubio C, López-Trascasa M, Sadallah S, Schifferli JA.

    Blood Cells Mol Dis. 2002 Sep-Oct;29(2):200-12.PMID: 12490287 [PubMed - indexed for MEDLINE]Related articles

    31.

    Structural and functional characterization of factor H mutations associated with atypical hemolytic uremic syndrome.

    Sánchez-Corral P, Pérez-Caballero D, Huarte O, Simckes AM, Goicoechea E, López-Trascasa M, de Córdoba SR.

    Am J Hum Genet. 2002 Dec;71(6):1285-95. Epub 2002 Nov 6.PMID: 12424708 [PubMed - indexed for MEDLINE]Related articlesFree article

    32.

    Detection of C1 inhibitor (SERPING1/C1NH) mutations in exon 8 in patients with hereditary angioedema: evidence for 10 novel mutations.

    Blanch A, Roche O, López-Granados E, Fontán G, López-Trascasa M.

    Hum Mutat. 2002 Nov;20(5):405-6. Erratum in: Hum Mutat. 2003 Jan;21(1):102.. PMID: 12402344 [PubMed - indexed for MEDLINE]Related articles

    33.

    Angioedema and transient acquired C1 inhibitor functional deficiency in HIV infection: case report.

    Reche M, Caballero T, López-Trascasa M, Arribas JR, López Serrano MC.

    AIDS. 2002 Jul 26;16(11):1561. No abstract available. PMID: 12131197 [PubMed - indexed for MEDLINE]Related articles

    34.

    Polyclonal autoantibodies against C1 inhibitor in a case of acquired angioedema.

    Ponce IM, Caballero T, Reche M, Piteiro AB, López-Serrano MC, Fontán G, López-Trascasa M.

    Ann Allergy Asthma Immunol. 2002 Jun;88(6):632-7.PMID: 12086372 [PubMed - indexed for MEDLINE]Related articles

    35.

    Complement interaction with trypanosomatid promastigotes in normal human serum.

    Domínguez M, Moreno I, López-Trascasa M, Toraño A.

    J Exp Med. 2002 Feb 18;195(4):451-9.PMID: 11854358 [PubMed - indexed for MEDLINE]Related articlesFree article

    36.

    Complement factor I deficiency associated with recurrent meningitis coinciding with menstruation.

    González-Rubio C, Ferreira-Cerdán A, Ponce IM, Arpa J, Fontán G, López-Trascasa M.

    Arch Neurol. 2001 Nov;58(11):1923-8.PMID: 11709004 [PubMed - indexed for MEDLINE]Related articlesFree article

    37.

    C4 deficiency in chronic angioedema.

    Azofra J, López-Trascasa M.

    Allergy. 2001 Nov;56(11):1106-7. No abstract available. PMID: 11703231 [PubMed - indexed for MEDLINE]Related articles

    38.

    Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome.

    Pérez-Caballero D, González-Rubio C, Gallardo ME, Vera M, López-Trascasa M, Rodríguez de Córdoba S, Sánchez-Corral P.

    Am J Hum Genet. 2001 Feb;68(2):478-84. Epub 2001 Jan 17.PMID: 11170895 [PubMed - indexed for MEDLINE]Related articlesFree article

    39.

    Acquired C1 esterase inhibitor deficiency.

    Caballero T, Concepcion Lopez-Serrano M, Lopez-Trascasa M.

    Ann Intern Med. 2000 Nov 21;133(10):837; author reply 839. No abstract available. PMID: 11085850 [PubMed - indexed for MEDLINE]Related articlesFree article

    40.

    Internalization of factor J and cellular signalization after factor J-cell interaction.

    Larrucea S, Cambronero R, González-Rubio C, Fraile B, Gamallo C, Fontán G, López-Trascasa M.

    Biochem Biophys Res Commun. 1999 Dec 9;266(1):51-7.PMID: 10581163 [PubMed - indexed for MEDLINE]Related articles

    41.

    A novel nonsense mutation at Glu-631 in a Spanish family with complement component 7 deficiency.

    Horiuchi T, Ferrer JM, Serra P, Matamoros N, López-Trascasa M, Hashimura C, Niho Y.

    J Hum Genet. 1999;44(3):215-8.PMID: 10319591 [PubMed - indexed for MEDLINE]Related articles

    42.

    Cellular adhesion mediated by factor J, a complement inhibitor. Evidence for nucleolin involvement.

    Larrucea S, González-Rubio C, Cambronero R, Ballou B, Bonay P, López-Granados E, Bouvet P, Fontán G, Fresno M, López-Trascasa M.

    J Biol Chem. 1998 Nov 27;273(48):31718-25.PMID: 9822633 [PubMed - indexed for MEDLINE]Related articlesFree article

    43.

    Elevated factor J levels in synovial fluid from patients with inflammatory arthropathies.

    González-Rubio C, Saboya-Palero A, Pascual-Salcedo D, Balsa A, Fontán G, López-Trascasa M.

    Immunopharmacology. 1997 Dec;38(1-2):159-65.PMID: 9476127 [PubMed - indexed for MEDLINE]Related articles

    44.

    Modulation of C4b-binding protein isoforms during the acute phase response caused by orthopedic surgery.

    Criado-García O, González-Rubio C, López-Trascasa M, Pascual-Salcedo D, Munuera L, Rodríguez de Córdoba S.

    Haemostasis. 1997 Jan-Feb;27(1):25-34.PMID: 9097083 [PubMed - indexed for MEDLINE]Related articles

    45.

    Factor J, an inhibitor of the classical and alternative complement pathway, does not inhibit esterolysis by factor D.

    González-Rubio C, González-Muñiz R, Jiménez-Clavero MA, Fontán G, López-Trascasa M.

    Biochim Biophys Acta. 1996 Jul 18;1295(2):174-8.PMID: 8695643 [PubMed - indexed for MEDLINE]Related articles

    46.

    [Deficiencies of C1 inhibitor: hereditary and acquired angioedema]

    Porcel-Pérez JM, López-Trascasa M.

    Rev Clin Esp. 1996 Mar;196 Spec No:26-30. Review. Spanish. No abstract available. PMID: 9206804 [PubMed - indexed for MEDLINE]Related articles

    47.

    Cell surface molecules related to factor J in human lymphoid cells and cell lines.

    Jiménez-Clavero MA, González-Rubio C, Larrucea S, Gamallo C, Fontán G, López-Trascasa M.

    J Immunol. 1995 Aug 15;155(4):2143-50.PMID: 7636262 [PubMed - indexed for MEDLINE]Related articles

    48.

    Crucial residues in the carboxy-terminal end of C1 inhibitor revealed by pathogenic mutants impaired in secretion or function.

    Verpy E, Couture-Tosi E, Eldering E, Lopez-Trascasa M, Späth P, Meo T, Tosi M.

    J Clin Invest. 1995 Jan;95(1):350-9.PMID: 7814636 [PubMed - indexed for MEDLINE]Related articlesFree article

    49.

    The inhibitory effect of factor J on the alternative complement pathway.

    González-Rubio C, Jiménez-Clavero MA, Fontán G, López-Trascasa M.

    J Biol Chem. 1994 Oct 21;269(42):26017-24.PMID: 7929312 [PubMed - indexed for MEDLINE]Related articlesFree article

    50.

    Factor J, a human inhibitor of complement C1, is a cationic, highly glycosylated protein.

    Jiménez-Clavero MA, González-Rubio C, Fontán G, López-Trascasa M.

    Immunol Lett. 1994 Oct;42(3):185-90.PMID: 7890318 [PubMed - indexed for MEDLINE]Related articles

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