PubMed

Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.

Paterson AD, Lopes-Virella MF, Waggott D, Boright AP, Hosseini SM, Carter RE, Shen E, Mirea L, Bharaj B, Sun L, Bull SB; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group.

Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1958-67. Epub 2009 Sep 3.PMID: 19729612 [PubMed - in process]Related articles

Periodontal disease status in gullah african americans with type 2 diabetes living in South Carolina.

Fernandes JK, Wiegand RE, Salinas CF, Grossi SG, Sanders JJ, Lopes-Virella MF, Slate EH.

J Periodontol. 2009 Jul;80(7):1062-8.PMID: 19563285 [PubMed - indexed for MEDLINE]Related articles

Clinical significance of the humoral immune response to modified LDL.

Lopes-Virella MF, Virella G.

Clin Immunol. 2009 May 7. [Epub ahead of print]PMID: 19427818 [PubMed - as supplied by publisher]Related articles

Interleukin-6 released from fibroblasts is essential for up-regulation of matrix metalloproteinase-1 expression by U937 macrophages in coculture: cross-talking between fibroblasts and U937 macrophages exposed to high glucose.

Sundararaj KP, Samuvel DJ, Li Y, Sanders JJ, Lopes-Virella MF, Huang Y.

J Biol Chem. 2009 May 15;284(20):13714-24. Epub 2009 Mar 23.PMID: 19307187 [PubMed - indexed for MEDLINE]Related articlesFree article

Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation.

Samuvel DJ, Sundararaj KP, Nareika A, Lopes-Virella MF, Huang Y.

J Immunol. 2009 Feb 15;182(4):2476-84.PMID: 19201903 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk factors related to inflammation and endothelial dysfunction in the DCCT/EDIC cohort and their relationship with nephropathy and macrovascular complications.

Lopes-Virella MF, Carter RE, Gilbert GE, Klein RL, Jaffa M, Jenkins AJ, Lyons TJ, Garvey WT, Virella G; Diabetes Control and Complications Trial/Epidemiology of Diabetes Intervention and Complications Cohort Study Group.

Diabetes Care. 2008 Oct;31(10):2006-12. Epub 2008 Jul 15.PMID: 18628568 [PubMed - indexed for MEDLINE]Related articlesFree article

A trend of increase in periodontal interleukin-6 expression across patients with neither diabetes nor periodontal disease, patients with periodontal disease alone, and patients with both diseases.

Cole CM, Sundararaj KP, Leite RS, Nareika A, Slate EH, Sanders JJ, Lopes-Virella MF, Huang Y.

J Periodontal Res. 2008 Dec;43(6):717-22. Epub 2008 Jul 3.PMID: 18627438 [PubMed - indexed for MEDLINE]Related articles

Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation.

Sundararaj KP, Samuvel DJ, Li Y, Nareika A, Slate EH, Sanders JJ, Lopes-Virella MF, Huang Y.

J Leukoc Biol. 2008 Oct;84(4):1120-9. Epub 2008 Jul 14.PMID: 18625914 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells.

Hammad SM, Twal WO, Barth JL, Smith KJ, Saad AF, Virella G, Argraves WS, Lopes-Virella MF.

Atherosclerosis. 2009 Feb;202(2):394-404. Epub 2008 May 28.PMID: 18597759 [PubMed - indexed for MEDLINE]Related articles

High glucose and interferon gamma synergistically stimulate MMP-1 expression in U937 macrophages by increasing transcription factor STAT1 activity.

Nareika A, Sundararaj KP, Im YB, Game BA, Lopes-Virella MF, Huang Y.

Atherosclerosis. 2009 Feb;202(2):363-71. Epub 2008 Jun 30.PMID: 18586252 [PubMed - indexed for MEDLINE]Related articles

Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy.

Virella G, Carter RE, Saad A, Crosswell EG, Game BA; DCCT/EDIC Study Group, Lopes-Virella MF.

Clin Immunol. 2008 Jun;127(3):394-400.PMID: 18533284 [PubMed - indexed for MEDLINE]Related articlesFree article

Atherogenesis and the humoral immune response to modified lipoproteins.

Virella G, Lopes-Virella MF.

Atherosclerosis. 2008 Oct;200(2):239-46. Epub 2008 Apr 12. Review.PMID: 18513726 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kappaB and AP-1 activities.

Nareika A, Im YB, Game BA, Slate EH, Sanders JJ, London SD, Lopes-Virella MF, Huang Y.

J Endocrinol. 2008 Jan;196(1):45-55.PMID: 18180316 [PubMed - indexed for MEDLINE]Related articlesFree article

Intensive treatment of diabetes is associated with a reduced rate of peripheral arterial calcification in the diabetes control and complications trial.

Carter RE, Lackland DT, Cleary PA, Yim E, Lopes-Virella MF, Gilbert GE, Orchard TJ; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group.

Diabetes Care. 2007 Oct;30(10):2646-8. Epub 2007 Jul 10. No abstract available. PMID: 17623823 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose-boosted inflammatory responses to lipopolysaccharide are suppressed by statin.

Nareika A, Maldonado A, He L, Game BA, Slate EH, Sanders JJ, London SD, Lopes-Virella MF, Huang Y.

J Periodontal Res. 2007 Feb;42(1):31-8.PMID: 17214637 [PubMed - indexed for MEDLINE]Related articles

Pioglitazone inhibits connective tissue growth factor expression in advanced atherosclerotic plaques in low-density lipoprotein receptor-deficient mice.

Game BA, He L, Jarido V, Nareika A, Jaffa AA, Lopes-Virella MF, Huang Y.

Atherosclerosis. 2007 May;192(1):85-91. Epub 2006 Aug 9.PMID: 16901490 [PubMed - indexed for MEDLINE]Related articles

OxLDL immune complexes activate complement and induce cytokine production by MonoMac 6 cells and human macrophages.

Saad AF, Virella G, Chassereau C, Boackle RJ, Lopes-Virella MF.

J Lipid Res. 2006 Sep;47(9):1975-83. Epub 2006 Jun 27.PMID: 16804192 [PubMed - indexed for MEDLINE]Related articlesFree article

Immune complexes containing modified lipoproteins are related to the progression of internal carotid intima-media thickness in patients with type 1 diabetes.

Lopes-Virella MF, McHenry MB, Lipsitz S, Yim E, Wilson PF, Lackland DT, Lyons T, Jenkins AJ, Virella G; DCCT/EDIC Research Group.

Atherosclerosis. 2007 Feb;190(2):359-69. Epub 2006 Mar 10.PMID: 16530770 [PubMed - indexed for MEDLINE]Related articles

Oxidized LDL immune complexes induce release of sphingosine kinase in human U937 monocytic cells.

Hammad SM, Taha TA, Nareika A, Johnson KR, Lopes-Virella MF, Obeid LM.

Prostaglandins Other Lipid Mediat. 2006 Mar;79(1-2):126-40. Epub 2006 Jan 31.PMID: 16516816 [PubMed - indexed for MEDLINE]Related articles

The immunogenicity of modified lipoproteins.

Lopes-Virella MF, Thorpe SR, Derrick MB, Chassereau C, Virella G.

Ann N Y Acad Sci. 2005 Jun;1043:367-78. Review.PMID: 16037258 [PubMed - indexed for MEDLINE]Related articles

Markers of endothelial dysfunction in the prediction of coronary artery disease in type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study.

Costacou T, Lopes-Virella MF, Zgibor JC, Virella G, Otvos J, Walsh M, Orchard TJ.

J Diabetes Complications. 2005 Jul-Aug;19(4):183-93.PMID: 15993351 [PubMed - indexed for MEDLINE]Related articles

Sodium lactate increases LPS-stimulated MMP and cytokine expression in U937 histiocytes by enhancing AP-1 and NF-kappaB transcriptional activities.

Nareika A, He L, Game BA, Slate EH, Sanders JJ, London SD, Lopes-Virella MF, Huang Y.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E534-42. Epub 2005 Jun 7.PMID: 15941782 [PubMed - indexed for MEDLINE]Related articlesFree article

Iron loading increases cholesterol accumulation and macrophage scavenger receptor I expression in THP-1 mononuclear phagocytes.

Kraml PJ, Klein RL, Huang Y, Nareika A, Lopes-Virella MF.

Metabolism. 2005 Apr;54(4):453-9. Erratum in: Metabolism. 2005 Jul;54(7):982. PMID: 15798950 [PubMed - indexed for MEDLINE]Related articles

Development of capture assays for different modifications of human low-density lipoprotein.

Virella G, Derrick MB, Pate V, Chassereau C, Thorpe SR, Lopes-Virella MF.

Clin Diagn Lab Immunol. 2005 Jan;12(1):68-75.PMID: 15642987 [PubMed - indexed for MEDLINE]Related articlesFree article

The prospective association between adiponectin and coronary artery disease among individuals with type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study.

Costacou T, Zgibor JC, Evans RW, Otvos J, Lopes-Virella MF, Tracy RP, Orchard TJ.

Diabetologia. 2005 Jan;48(1):41-8. Epub 2004 Dec 23.PMID: 15616802 [PubMed - indexed for MEDLINE]Related articles

Pre-exposure to high glucose augments lipopolysaccharide-stimulated matrix metalloproteinase-1 expression by human U937 histiocytes.

Maldonado A, He L, Game BA, Nareika A, Sanders JJ, London SD, Lopes-Virella MF, Huang Y.

J Periodontal Res. 2004 Dec;39(6):415-23.PMID: 15491346 [PubMed - indexed for MEDLINE]Related articles

Definition of the immunogenic forms of modified human LDL recognized by human autoantibodies and by rabbit hyperimmune antibodies.

Virella G, Thorpe SR, Alderson NL, Derrick MB, Chassereau C, Rhett JM, Lopes-Virella MF.

J Lipid Res. 2004 Oct;45(10):1859-67. Epub 2004 Jul 16.PMID: 15258197 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of simvastatin as an immunomodulator in type 2 diabetes.

Lopes-Virella MF, Mironova M, Stephan E, Durazo-Arvizu R, Virella G.

Diabetes Care. 2004 Apr;27(4):908-13.PMID: 15047647 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized LDL further enhances expression of adhesion molecules in Chlamydophila pneumoniae-infected endothelial cells.

Vielma SA, Mironova M, Ku JR, Lopes-Virella MF.

J Lipid Res. 2004 May;45(5):873-80. Epub 2004 Feb 16.PMID: 14967815 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of immune and inflammatory processes in the development of macrovascular disease in diabetes.

Lopes-Virella MF, Virella G.

Front Biosci. 2003 Sep 1;8:s750-68. Review.PMID: 12957881 [PubMed - indexed for MEDLINE]Related articles

Regulation of MMP-1 expression in vascular endothelial cells by insulin sensitizing thiazolidinediones.

Game BA, Xu M, Lopes-Virella MF, Huang Y.

Atherosclerosis. 2003 Aug;169(2):235-43.PMID: 12921974 [PubMed - indexed for MEDLINE]Related articles

Lipoprotein autoantibodies: measurement and significance.

Virella G, Lopes-Virella MF.

Clin Diagn Lab Immunol. 2003 Jul;10(4):499-505. Review. No abstract available. PMID: 12853376 [PubMed - indexed for MEDLINE]Related articlesFree article

LDL immune complexes stimulate LDL receptor expression in U937 histiocytes via extracellular signal-regulated kinase and AP-1.

Fu Y, Huang Y, Bandyopadhyay S, Virella G, Lopes-Virella MF.

J Lipid Res. 2003 Jul;44(7):1315-21. Epub 2003 May 1.PMID: 12730303 [PubMed - indexed for MEDLINE]Related articlesFree article

Chlamydophila pneumoniae induces ICAM-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB.

Vielma SA, Krings G, Lopes-Virella MF.

Circ Res. 2003 May 30;92(10):1130-7. Epub 2003 Apr 24.PMID: 12714566 [PubMed - indexed for MEDLINE]Related articlesFree article

Humoral immunity and atherosclerosis.

Virella G, Lopes-Virella MF.

Nat Med. 2003 Mar;9(3):243-4; author reply 244-5. No abstract available. PMID: 12612552 [PubMed - indexed for MEDLINE]Related articles

Autoimmune response to advanced glycosylation end-products of human LDL.

Virella G, Thorpe SR, Alderson NL, Stephan EM, Atchley D, Wagner F, Lopes-Virella MF; DCCT/EDIC Research Group.

J Lipid Res. 2003 Mar;44(3):487-93. Epub 2002 Dec 1.PMID: 12562876 [PubMed - indexed for MEDLINE]Related articlesFree article

Proatherogenic and proinflammatory properties of immune complexes prepared with purified human oxLDL antibodies and human oxLDL.

Virella G, Atchley D, Koskinen S, Zheng D, Lopes-Virella MF; DCCT/EDIC Research Group.

Clin Immunol. 2002 Oct;105(1):81-92.PMID: 12483997 [PubMed - indexed for MEDLINE]Related articles

Oxidized LDL-anti-oxidized LDL immune complexes and diabetic nephropathy.

Atchley DH, Lopes-Virella MF, Zheng D, Kenny D, Virella G.

Diabetologia. 2002 Nov;45(11):1562-71. Epub 2002 Oct 12.PMID: 12436340 [PubMed - indexed for MEDLINE]Related articles

The adipocyte lipid binding protein (ALBP/aP2) gene facilitates foam cell formation in human THP-1 macrophages.

Fu Y, Luo N, Lopes-Virella MF, Garvey WT.

Atherosclerosis. 2002 Dec;165(2):259-69.PMID: 12417276 [PubMed - indexed for MEDLINE]Related articles

IFN-gamma pretreatment augments immune complex-induced matrix metalloproteinase-1 expression in U937 histiocytes.

Anderson F, Game BA, Atchley D, Xu M, Lopes-Virella MF, Huang Y.

Clin Immunol. 2002 Feb;102(2):200-7.PMID: 11846463 [PubMed - indexed for MEDLINE]Related articles

Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages.

Fu Y, Luo N, Lopes-Virella MF.

Atherosclerosis. 2002 Jan;160(1):11-20.PMID: 11755918 [PubMed - indexed for MEDLINE]Related articles

Quercetin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells through extracellular signal-regulated kinase.

Song L, Xu M, Lopes-Virella MF, Huang Y.

Arch Biochem Biophys. 2001 Jul 1;391(1):72-8.PMID: 11414687 [PubMed - indexed for MEDLINE]Related articles

Oxidized LDL differentially regulates MMP-1 and TIMP-1 expression in vascular endothelial cells.

Huang Y, Song L, Wu S, Fan F, Lopes-Virella MF.

Atherosclerosis. 2001 May;156(1):119-25.PMID: 11369004 [PubMed - indexed for MEDLINE]Related articles

Effect of inflammatory cytokines on the metabolism of low-density lipoproteins by human vascular endothelial cells.

Klein RL, Ascenção JL, Mironova M, Huang Y, Lopes-Virella MF.

Metabolism. 2001 Jan;50(1):99-106.PMID: 11172482 [PubMed - indexed for MEDLINE]Related articles

Expression of adhesion molecules by human endothelial cells exposed to oxidized low density lipoprotein. Influences of degree of oxidation and location of oxidized LDL.

Takei A, Huang Y, Lopes-Virella MF.

Atherosclerosis. 2001 Jan;154(1):79-86.PMID: 11137085 [PubMed - indexed for MEDLINE]Related articles

Fc-gamma receptor cross-linking by immune complexes induces matrix metalloproteinase-1 in U937 cells via mitogen-activated protein kinase.

Huang Y, Fleming AJ, Wu S, Virella G, Lopes-Virella MF.

Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2533-8.PMID: 11116049 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages.

Fu Y, Luo N, Lopes-Virella MF.

J Lipid Res. 2000 Dec;41(12):2017-23.PMID: 11108735 [PubMed - indexed for MEDLINE]Related articlesFree article

The preparation of copper-oxidized LDL for the measurement of oxidized LDL antibodies by EIA.

Lopes-Virella MF, Koskinen S, Mironova M, Horne D, Klein R, Chassereau C, Enockson C, Virella G.

Atherosclerosis. 2000 Sep;152(1):107-15.PMID: 10996345 [PubMed - indexed for MEDLINE]Related articles

Anti-modified LDL antibodies, LDL-containing immune complexes, and susceptibility of LDL to in vitro oxidation in patients with type 2 diabetes.

Mironova MA, Klein RL, Virella GT, Lopes-Virella MF.

Diabetes. 2000 Jun;49(6):1033-41.PMID: 10866057 [PubMed - indexed for MEDLINE]Related articlesFree article

Use of fenofibrate in the management of protease inhibitor-associated lipid abnormalities.

Thomas JC, Lopes-Virella MF, Del Bene VE, Cerveny JD, Taylor KB, McWhorter LS, Bultemeier NC.

Pharmacotherapy. 2000 Jun;20(6):727-34.PMID: 10853629 [PubMed - indexed for MEDLINE]Related articles