PubMed

Diabetes and apoptosis: neural crest cells and neural tube.

Chappell JH Jr, Wang XD, Loeken MR.

Apoptosis. 2009 Dec;14(12):1472-83.PMID: 19333760 [PubMed - in process]Related articles

How TGF-beta and PAX3 regulate suntanning.

Loeken MR.

Pigment Cell Melanoma Res. 2009 Apr;22(2):146-7. Epub 2009 Jan 16. No abstract available. PMID: 19207218 [PubMed - indexed for MEDLINE]Related articles

Challenges in understanding diabetic embryopathy.

Loeken MR.

Diabetes. 2008 Dec;57(12):3187-8. No abstract available. PMID: 19033406 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac outflow tract septation failure in Pax3-deficient embryos is due to p53-dependent regulation of migrating cardiac neural crest.

Morgan SC, Lee HY, Relaix F, Sandell LL, Levorse JM, Loeken MR.

Mech Dev. 2008 Sep-Oct;125(9-10):757-67. Epub 2008 Jul 13.PMID: 18672055 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress during diabetic pregnancy disrupts cardiac neural crest migration and causes outflow tract defects.

Morgan SC, Relaix F, Sandell LL, Loeken MR.

Birth Defects Res A Clin Mol Teratol. 2008 Jun;82(6):453-63.PMID: 18435457 [PubMed - indexed for MEDLINE]Related articles

Expression of the gene encoding the high-Km glucose transporter 2 by the early postimplantation mouse embryo is essential for neural tube defects associated with diabetic embryopathy.

Li R, Thorens B, Loeken MR.

Diabetologia. 2007 Mar;50(3):682-9. Epub 2007 Jan 18.PMID: 17235524 [PubMed - indexed for MEDLINE]Related articles

Establishment of new mouse embryonic stem cell lines is improved by physiological glucose and oxygen.

Wang F, Thirumangalathu S, Loeken MR.

Cloning Stem Cells. 2006 Summer;8(2):108-16.PMID: 16776602 [PubMed - indexed for MEDLINE]Related articles

Advances in understanding the molecular causes of diabetes-induced birth defects.

Loeken MR.

J Soc Gynecol Investig. 2006 Jan;13(1):2-10. Epub 2005 Nov 21.PMID: 16303321 [PubMed - indexed for MEDLINE]Related articles

Hypoxic stress in diabetic pregnancy contributes to impaired embryo gene expression and defective development by inducing oxidative stress.

Li R, Chase M, Jung SK, Smith PJ, Loeken MR.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E591-9. Epub 2005 May 31.PMID: 15928021 [PubMed - indexed for MEDLINE]Related articlesFree article

Current perspectives on the causes of neural tube defects resulting from diabetic pregnancy.

Loeken MR.

Am J Med Genet C Semin Med Genet. 2005 May 15;135C(1):77-87. Review.PMID: 15800853 [PubMed - indexed for MEDLINE]Related articles

Activation of the hexosamine pathway causes oxidative stress and abnormal embryo gene expression: involvement in diabetic teratogenesis.

Horal M, Zhang Z, Stanton R, Virkamäki A, Loeken MR.

Birth Defects Res A Clin Mol Teratol. 2004 Aug;70(8):519-27.PMID: 15329829 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia-induced oxidative stress in diabetic complications.

King GL, Loeken MR.

Histochem Cell Biol. 2004 Oct;122(4):333-8. Epub 2004 Jul 15. Review.PMID: 15257460 [PubMed - indexed for MEDLINE]Related articles

Free radicals and birth defects.

Loeken MR.

J Matern Fetal Neonatal Med. 2004 Jan;15(1):6-14. Review.PMID: 15101606 [PubMed - indexed for MEDLINE]Related articles

Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects.

Chang TI, Horal M, Jain SK, Wang F, Patel R, Loeken MR.

Diabetologia. 2003 Apr;46(4):538-45. Epub 2003 Mar 26.PMID: 12739027 [PubMed - indexed for MEDLINE]Related articles

Polymorphic susceptibility to the molecular causes of neural tube defects during diabetic embryopathy.

Pani L, Horal M, Loeken MR.

Diabetes. 2002 Sep;51(9):2871-4.PMID: 12196484 [PubMed - indexed for MEDLINE]Related articlesFree article

Maternal diabetes increases the risk of caudal regression caused by retinoic acid.

Chan BW, Chan KS, Koide T, Yeung SM, Leung MB, Copp AJ, Loeken MR, Shiroishi T, Shum AS.

Diabetes. 2002 Sep;51(9):2811-6.PMID: 12196475 [PubMed - indexed for MEDLINE]Related articlesFree article

Diacylglycerol production and protein kinase C activity are increased in a mouse model of diabetic embryopathy.

Hiramatsu Y, Sekiguchi N, Hayashi M, Isshiki K, Yokota T, King GL, Loeken MR.

Diabetes. 2002 Sep;51(9):2804-10.PMID: 12196474 [PubMed - indexed for MEDLINE]Related articlesFree article

Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis.

Pani L, Horal M, Loeken MR.

Genes Dev. 2002 Mar 15;16(6):676-80.PMID: 11914272 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that elevated glucose causes altered gene expression, apoptosis, and neural tube defects in a mouse model of diabetic pregnancy.

Fine EL, Horal M, Chang TI, Fortin G, Loeken MR.

Diabetes. 1999 Dec;48(12):2454-62.PMID: 10580436 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotoxicity and diabetic embryopathy: impaired expression of developmental control genes as a cause of defective morphogenesis.

Chang TI, Loeken MR.

Semin Reprod Endocrinol. 1999;17(2):153-65. Review.PMID: 10528366 [PubMed - indexed for MEDLINE]Related articles

Identification of Dep-1, a new gene regulated by the transcription factor Pax-3, as a marker for altered embryonic gene expression during diabetic pregnancy.

Cai J, Phelan SA, Hill AL, Loeken MR.

Diabetes. 1998 Nov;47(11):1803-5. No abstract available. PMID: 9792553 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a new binding motif for the paired domain of Pax-3 and unusual characteristics of spacing of bipartite recognition elements on binding and transcription activation.

Phelan SA, Loeken MR.

J Biol Chem. 1998 Jul 24;273(30):19153-9.PMID: 9668101 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced expression of pax-3 is associated with overexpression of cdc46 in the mouse embryo.

Hill AL, Phelan SA, Loeken MR.

Dev Genes Evol. 1998 May;208(3):128-34.PMID: 9601985 [PubMed - indexed for MEDLINE]Related articles

Neural tube defects in embryos of diabetic mice: role of the Pax-3 gene and apoptosis.

Phelan SA, Ito M, Loeken MR.

Diabetes. 1997 Jul;46(7):1189-97.PMID: 9200655 [PubMed - indexed for MEDLINE]Related articles

Expression of the gene encoding glycogen phosphorylase is elevated in diabetic rat skeletal muscle and is regulated by insulin and cyclic AMP.

Reynet C, Kahn CR, Loeken MR.

Diabetologia. 1996 Feb;39(2):183-9.PMID: 8635670 [PubMed - indexed for MEDLINE]Related articles

Multiple, distinct trans-activation functions are encoded by the simian virus 40 large T and small t antigens, only some of which require the 82-residue amino-terminal common domain.

Loeken MR.

J Virol. 1993 Dec;67(12):7684-9.PMID: 8230491 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of mutation of the CREB binding site of the somatostatin promoter on cyclic AMP responsiveness in CV-1 cells.

Loeken MR.

Gene Expr. 1993;3(3):253-64.PMID: 7912577 [PubMed - indexed for MEDLINE]Related articles

Simian virus 40 small t antigen trans activates the adenovirus E2A promoter by using mechanisms distinct from those used by adenovirus E1A.

Loeken MR.

J Virol. 1992 Apr;66(4):2551-5.PMID: 1532215 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of simian virus 40 (SV40) small t antigen in trans activation of SV40 early and late promoters.

Bikel I, Loeken MR.

J Virol. 1992 Mar;66(3):1489-94.PMID: 1310761 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of endothelin-1 gene expression by insulin in endothelial cells.

Oliver FJ, de la Rubia G, Feener EP, Lee ME, Loeken MR, Shiba T, Quertermous T, King GL.

J Biol Chem. 1991 Dec 5;266(34):23251-6.PMID: 1744120 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneity of expression and secretion of native and mutant [AspB10]insulin in AtT20 cells.

Ferber S, Gross DJ, Villa-Komaroff L, Danehy F, Vollenweider F, Meyer K, Loeken MR, Kahn CR, Halban PA.

Mol Endocrinol. 1991 Mar;5(3):319-26.PMID: 1890988 [PubMed - indexed for MEDLINE]Related articles

The adenovirus EIIA enhancer. Analysis of regulatory sequences and changes in binding activity of ATF and EIIF following adenovirus infection.

Loeken MR, Brady J.

J Biol Chem. 1989 Apr 15;264(11):6572-9.PMID: 2522934 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of the adenovirus E2 promoter by simian virus 40 T antigen or E1A occurs by different mechanisms.

Loeken MR, Khoury G, Brady J.

Mol Cell Biol. 1986 Jun;6(6):2020-6.PMID: 3023915 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction between two transcriptional control sequences required for tumor-antigen-mediated simian virus 40 late gene expression.

Brady J, Loeken MR, Khoury G.

Proc Natl Acad Sci U S A. 1985 Nov;82(21):7299-303.PMID: 2997782 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct evidence for de-novo synthesis of LH receptors in cultured pig granulosa cells in response to FSH.

Loeken MR, Channing CP.

J Reprod Fertil. 1985 Mar;73(2):343-51.PMID: 2985778 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of maternal IgG subpopulations which are transported into the chicken oocyte.

Loeken MR, Roth TF.

Immunology. 1983 May;49(1):21-8.PMID: 6840806 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulatory effect of luteinizing hormone upon relaxin secretion by cultured porcine preovulatory granulosa cells.

Loeken MR, Channing CP, D'Eletto R, Weiss G.

Endocrinology. 1983 Feb;112(2):769-71.PMID: 6848371 [PubMed - indexed for MEDLINE]Related articles

Intraovarian control of granulosa cell luteinization.

Osteen KG, Loeken MR, Channing CP.

Endocrinol Exp. 1982 Nov;16(3-4):301-9.PMID: 6816575 [PubMed - indexed for MEDLINE]Related articles