PubMed

miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221.

Kotani A, Ha D, Hsieh J, Rao PK, Schotte D, den Boer ML, Armstrong SA, Lodish HF.

Blood. 2009 Nov 5;114(19):4169-78. Epub 2009 Sep 11.PMID: 19749093 [PubMed - in process]Related articles

Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure.

Rao PK, Toyama Y, Chiang HR, Gupta S, Bauer M, Medvid R, Reinhardt F, Liao R, Krieger M, Jaenisch R, Lodish HF, Blelloch R.

Circ Res. 2009 Sep 11;105(6):585-94. Epub 2009 Aug 13.PMID: 19679836 [PubMed - indexed for MEDLINE]Related articles

Targeting microRNAs in obesity.

Xie H, Sun L, Lodish HF.

Expert Opin Ther Targets. 2009 Oct;13(10):1227-38.PMID: 19650761 [PubMed - in process]Related articles

MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets.

Le MT, Xie H, Zhou B, Chia PH, Rizk P, Um M, Udolph G, Yang H, Lim B, Lodish HF.

Mol Cell Biol. 2009 Oct;29(19):5290-305. Epub 2009 Jul 27.PMID: 19635812 [PubMed - indexed for MEDLINE]Related articles

ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling.

Wood AD, Chen E, Donaldson IJ, Hattangadi S, Burke KA, Dawson MA, Miranda-Saavedra D, Lodish HF, Green AR, Göttgens B.

Blood. 2009 Aug 27;114(9):1820-30. Epub 2009 Jul 1.PMID: 19571317 [PubMed - indexed for MEDLINE]Related articles

MicroRNA-125b is a novel negative regulator of p53.

Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V, Lodish HF, Lim B.

Genes Dev. 2009 Apr 1;23(7):862-76. Epub 2009 Mar 17.PMID: 19293287 [PubMed - indexed for MEDLINE]Related articlesFree article

MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity.

Xie H, Lim B, Lodish HF.

Diabetes. 2009 May;58(5):1050-7. Epub 2009 Feb 2.PMID: 19188425 [PubMed - indexed for MEDLINE]Related articlesFree article

Symmetric signaling by an asymmetric 1 erythropoietin: 2 erythropoietin receptor complex.

Zhang YL, Radhakrishnan ML, Lu X, Gross AW, Tidor B, Lodish HF.

Mol Cell. 2009 Jan 30;33(2):266-74.PMID: 19187767 [PubMed - indexed for MEDLINE]Related articles

Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.

Zhang J, Wang J, Liu Y, Sidik H, Young KH, Lodish HF, Fleming MD.

Blood. 2009 Feb 5;113(6):1304-14. Epub 2008 Dec 9.PMID: 19066392 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin.

Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Ge G, Spooner E, Hug C, Gimeno R, Lodish HF.

FASEB J. 2009 Jan;23(1):241-58. Epub 2008 Sep 11.PMID: 18787108 [PubMed - indexed for MEDLINE]Related articles

Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions.

Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Revett T, Gimeno R, Lodish HF.

Biochem J. 2008 Dec 1;416(2):161-77.PMID: 18783346 [PubMed - indexed for MEDLINE]Related articles

Cytokines regulating hematopoietic stem cell function.

Zhang CC, Lodish HF.

Curr Opin Hematol. 2008 Jul;15(4):307-11.PMID: 18536567 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells.

Huynh H, Iizuka S, Kaba M, Kirak O, Zheng J, Lodish HF, Zhang CC.

Stem Cells. 2008 Jun;26(6):1628-35. Epub 2008 Mar 27.PMID: 18369099 [PubMed - indexed for MEDLINE]Related articlesFree article

Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2.

Ji P, Jayapal SR, Lodish HF.

Nat Cell Biol. 2008 Mar;10(3):314-21. Epub 2008 Feb 10.PMID: 18264091 [PubMed - indexed for MEDLINE]Related articles

Micromanagement of the immune system by microRNAs.

Lodish HF, Zhou B, Liu G, Chen CZ.

Nat Rev Immunol. 2008 Feb;8(2):120-30. Review. Erratum in: Nat Rev Immunol. 2008 Mar;8(3):238. PMID: 18204468 [PubMed - indexed for MEDLINE]Related articles

Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation.

Zhang CC, Kaba M, Iizuka S, Huynh H, Lodish HF.

Blood. 2008 Apr 1;111(7):3415-23. Epub 2008 Jan 17.PMID: 18202223 [PubMed - indexed for MEDLINE]Related articlesFree article

Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F.

Lu X, Huang LJ, Lodish HF.

J Biol Chem. 2008 Feb 29;283(9):5258-66. Epub 2007 Dec 23.PMID: 18158285 [PubMed - indexed for MEDLINE]Related articlesFree article

Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity.

Liao MJ, Zhang CC, Zhou B, Zimonjic DB, Mani SA, Kaba M, Gifford A, Reinhardt F, Popescu NC, Guo W, Eaton EN, Lodish HF, Weinberg RA.

Cancer Res. 2007 Sep 1;67(17):8131-8.PMID: 17804725 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous K-ras signaling in erythroid differentiation.

Zhang J, Lodish HF.

Cell Cycle. 2007 Aug 15;6(16):1970-3. Epub 2007 Jun 10.PMID: 17721087 [PubMed - indexed for MEDLINE]Related articles

Regulation of erythrocyte lifespan: do reactive oxygen species set the clock?

Hattangadi SM, Lodish HF.

J Clin Invest. 2007 Aug;117(8):2075-7.PMID: 17671642 [PubMed - indexed for MEDLINE]Related articlesFree article

Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewal.

Tong W, Ibarra YM, Lodish HF.

Exp Hematol. 2007 Sep;35(9):1447-55. Epub 2007 Jul 16.PMID: 17637498 [PubMed - indexed for MEDLINE]Related articlesFree article

Alpha4beta1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development.

Eshghi S, Vogelezang MG, Hynes RO, Griffith LG, Lodish HF.

J Cell Biol. 2007 Jun 4;177(5):871-80. Erratum in: J Cell Biol. 2008 Apr 21;181(2):395. PMID: 17548514 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro erythropoiesis from bone marrow-derived progenitors provides a physiological assay for toxic and mutagenic compounds.

Shuga J, Zhang J, Samson LD, Lodish HF, Griffith LG.

Proc Natl Acad Sci U S A. 2007 May 22;104(21):8737-42. Epub 2007 May 14.PMID: 17502613 [PubMed - indexed for MEDLINE]Related articlesFree article

miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely.

Zhou B, Wang S, Mayr C, Bartel DP, Lodish HF.

Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7080-5. Epub 2007 Apr 16. Erratum in: Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):18070. PMID: 17438277 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways.

Zhang J, Liu Y, Beard C, Tuveson DA, Jaenisch R, Jacks TE, Lodish HF.

Blood. 2007 Jun 15;109(12):5238-41. Epub 2007 Feb 22.PMID: 17317860 [PubMed - indexed for MEDLINE]Related articlesFree article

JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.

Scott LM, Tong W, Levine RL, Scott MA, Beer PA, Stratton MR, Futreal PA, Erber WN, McMullin MF, Harrison CN, Warren AJ, Gilliland DG, Lodish HF, Green AR.

N Engl J Med. 2007 Feb 1;356(5):459-68.PMID: 17267906 [PubMed - indexed for MEDLINE]Related articlesFree article

The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms.

Tong W, Sulahian R, Gross AW, Hendon N, Lodish HF, Huang LJ.

J Biol Chem. 2006 Dec 15;281(50):38930-40. Epub 2006 Oct 19.PMID: 17052978 [PubMed - indexed for MEDLINE]Related articlesFree article

A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells.

Um M, Gross AW, Lodish HF.

Cell Signal. 2007 Mar;19(3):634-45. Epub 2006 Aug 30.PMID: 17045782 [PubMed - indexed for MEDLINE]Related articles

A revised model for AMP-activated protein kinase structure: The alpha-subunit binds to both the beta- and gamma-subunits although there is no direct binding between the beta- and gamma-subunits.

Wong KA, Lodish HF.

J Biol Chem. 2006 Nov 24;281(47):36434-42. Epub 2006 Sep 29.PMID: 17012231 [PubMed - indexed for MEDLINE]Related articlesFree article

Myogenic factors that regulate expression of muscle-specific microRNAs.

Rao PK, Kumar RM, Farkhondeh M, Baskerville S, Lodish HF.

Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8721-6. Epub 2006 May 26.PMID: 16731620 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice deleted for fatty acid transport protein 5 have defective bile acid conjugation and are protected from obesity.

Hubbard B, Doege H, Punreddy S, Wu H, Huang X, Kaushik VK, Mozell RL, Byrnes JJ, Stricker-Krongrad A, Chou CJ, Tartaglia LA, Lodish HF, Stahl A, Gimeno RE.

Gastroenterology. 2006 Apr;130(4):1259-69.PMID: 16618417 [PubMed - indexed for MEDLINE]Related articles

Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal.

Zhang CC, Steele AD, Lindquist S, Lodish HF.

Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2184-9. Epub 2006 Feb 7.PMID: 16467153 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells.

Zhang CC, Kaba M, Ge G, Xie K, Tong W, Hug C, Lodish HF.

Nat Med. 2006 Feb;12(2):240-5. Epub 2006 Jan 22.PMID: 16429146 [PubMed - indexed for MEDLINE]Related articlesFree article

Active conformation of the erythropoietin receptor: random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains.

Lu X, Gross AW, Lodish HF.

J Biol Chem. 2006 Mar 17;281(11):7002-11. Epub 2006 Jan 12.PMID: 16414957 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiapoptotic effects of erythropoietin in differentiated neuroblastoma SH-SY5Y cells require activation of both the STAT5 and AKT signaling pathways.

Um M, Lodish HF.

J Biol Chem. 2006 Mar 3;281(9):5648-56. Epub 2006 Jan 4.PMID: 16407271 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP).

Gross AW, Lodish HF.

J Biol Chem. 2006 Jan 27;281(4):2024-32. Epub 2005 Nov 11.PMID: 16286456 [PubMed - indexed for MEDLINE]Related articlesFree article

AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation.

Ghaffari S, Kitidis C, Zhao W, Marinkovic D, Fleming MD, Luo B, Marszalek J, Lodish HF.

Blood. 2006 Mar 1;107(5):1888-91. Epub 2005 Oct 27.PMID: 16254141 [PubMed - indexed for MEDLINE]Related articlesFree article

Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you.

Marszalek JR, Lodish HF.

Annu Rev Cell Dev Biol. 2005;21:633-57. Review.PMID: 16212510 [PubMed - indexed for MEDLINE]Related articles

Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway.

Zhao W, Kitidis C, Fleming MD, Lodish HF, Ghaffari S.

Blood. 2006 Feb 1;107(3):907-15. Epub 2005 Oct 4.PMID: 16204311 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo.

Zhang J, Lodish HF.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14605-10. Epub 2005 Oct 3.PMID: 16203968 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of the adipocyte hormone adiponectin in cardiovascular disease.

Hug C, Lodish HF.

Curr Opin Pharmacol. 2005 Apr;5(2):129-34. Review.PMID: 15780820 [PubMed - indexed for MEDLINE]Related articles

MicroRNAs as regulators of mammalian hematopoiesis.

Chen CZ, Lodish HF.

Semin Immunol. 2005 Apr;17(2):155-65. Review.PMID: 15737576 [PubMed - indexed for MEDLINE]Related articles

Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways.

Tong W, Zhang J, Lodish HF.

Blood. 2005 Jun 15;105(12):4604-12. Epub 2005 Feb 10.PMID: 15705783 [PubMed - indexed for MEDLINE]Related articlesFree article

Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion.

Zhang CC, Lodish HF.

Blood. 2005 Jun 1;105(11):4314-20. Epub 2005 Feb 8.PMID: 15701724 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism.

Marszalek JR, Kitidis C, Dirusso CC, Lodish HF.

J Biol Chem. 2005 Mar 18;280(11):10817-26. Epub 2005 Jan 17.PMID: 15655248 [PubMed - indexed for MEDLINE]Related articlesFree article

Medicine. Visfatin: a new adipokine.

Hug C, Lodish HF.

Science. 2005 Jan 21;307(5708):366-7. Epub 2004 Dec 16. No abstract available. PMID: 15604359 [PubMed - indexed for MEDLINE]Related articles

Points of view: lectures: can't learn with them, can't learn without them.

Lodish HF, Rodriguez RK, Klionsky DJ.

Cell Biol Educ. 2004 Winter;3(4):202-11. No abstract available. PMID: 15592591 [PubMed - indexed for MEDLINE]Related articlesFree article

Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.

Tong W, Lodish HF.

J Exp Med. 2004 Sep 6;200(5):569-80. Epub 2004 Aug 30.PMID: 15337790 [PubMed - indexed for MEDLINE]Related articlesFree article

A family of Acrp30/adiponectin structural and functional paralogs.

Wong GW, Wang J, Hug C, Tsao TS, Lodish HF.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10302-7. Epub 2004 Jul 1.PMID: 15231994 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin.

Hug C, Wang J, Ahmad NS, Bogan JS, Tsao TS, Lodish HF.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10308-13. Epub 2004 Jun 21.PMID: 15210937 [PubMed - indexed for MEDLINE]Related articlesFree article