PubMed

Protein kinase activation loop autophosphorylation in cis: overcoming a Catch-22 situation.

Lochhead PA.

Sci Signal. 2009 Jan 20;2(54):pe4.PMID: 19155529 [PubMed - indexed for MEDLINE]Related articles

A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation.

Lochhead PA, Kinstrie R, Sibbet G, Rawjee T, Morrice N, Cleghon V.

Mol Cell. 2006 Nov 17;24(4):627-33.PMID: 17188038 [PubMed - indexed for MEDLINE]Related articles

dDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.

Kinstrie R, Lochhead PA, Sibbet G, Morrice N, Cleghon V.

Biochem J. 2006 Aug 15;398(1):45-54.PMID: 16671894 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.

Lochhead PA, Sibbet G, Morrice N, Cleghon V.

Cell. 2005 Jun 17;121(6):925-36.PMID: 15960979 [PubMed - indexed for MEDLINE]Related articles

dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

Lochhead PA, Sibbet G, Kinstrie R, Cleghon T, Rylatt M, Morrison DK, Cleghon V.

Biochem J. 2003 Sep 1;374(Pt 2):381-91.PMID: 12786602 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity.

Patel S, Lochhead PA, Rena G, Fumagalli S, Pende M, Kozma SC, Thomas G, Sutherland C.

J Biol Chem. 2002 Mar 22;277(12):9889-95. Epub 2002 Jan 9.PMID: 11784721 [PubMed - indexed for MEDLINE]Related articlesFree article

Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression.

Patel S, Lochhead PA, Rena G, Sutherland C.

Biochem J. 2001 Nov 1;359(Pt 3):611-9.PMID: 11672436 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression.

Lochhead PA, Coghlan M, Rice SQ, Sutherland C.

Diabetes. 2001 May;50(5):937-46.PMID: 11334436 [PubMed - indexed for MEDLINE]Related articlesFree article

5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase.

Lochhead PA, Salt IP, Walker KS, Hardie DG, Sutherland C.

Diabetes. 2000 Jun;49(6):896-903.PMID: 10866040 [PubMed - indexed for MEDLINE]Related articlesFree article