PubMed

Short-term ethinylestradiol treatment suppresses inferior caval vein thrombosis in obese mice.

Cleuren AC, van Hoef B, Hoylaerts MF, van Vlijmen BJ, Lijnen HR.

Thromb Haemost. 2009 Nov;102(5):993-1000.PMID: 19888539 [PubMed - in process]Related articles

Thrombolytic efficacy of recombinant human microplasmin in a canine model of copper coil-induced coronary artery thrombosis.

Dommke C, Turschner O, Stassen JM, Van de Werf F, Lijnen HR, Verhamme P.

J Thromb Thrombolysis. 2009 Oct 16. [Epub ahead of print]PMID: 19834783 [PubMed - as supplied by publisher]Related articles

Neutralization of alpha(2)-antiplasmin by microplasmin: a randomized, double-blind, placebo-controlled, ascending-dose study in healthy male volunteers.

Pakola S, Cahillane G, Stassen JM, Lijnen HR, Verhamme P.

Clin Ther. 2009 Aug;31(8):1688-706.PMID: 19808128 [PubMed - in process]Related articles

Stromelysin-2 (MMP-10) deficiency does not affect adipose tissue formation in a mouse model of nutritionally induced obesity.

Lijnen HR, Van Hoef B, Rodriguez JA, Paramo JA.

Biochem Biophys Res Commun. 2009 Nov 13;389(2):378-81. Epub 2009 Sep 2.PMID: 19732744 [PubMed - indexed for MEDLINE]Related articles

Blood Vessel Density in De Novo Formed Adipose Tissue Is Decreased Upon Overexpression of TIMP-1.

Scroyen I, Jacobs F, Cosemans L, De Geest B, Lijnen HR.

Obesity (Silver Spring). 2009 Sep 3. [Epub ahead of print]PMID: 19730423 [PubMed - as supplied by publisher]Related articles

Angiogenesis and development of adipose tissue.

Christiaens V, Lijnen HR.

Mol Cell Endocrinol. 2009 Aug 15. [Epub ahead of print]PMID: 19686803 [PubMed - as supplied by publisher]Related articles

Role of plasminogen activation in neuronal organization and survival.

Ho-Tin-Noé B, Enslen H, Doeuvre L, Corsi JM, Lijnen HR, Anglés-Cano E.

Mol Cell Neurosci. 2009 Dec;42(4):288-95. Epub 2009 Aug 14.PMID: 19683575 [PubMed - in process]Related articles

Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein.

Suzuki Y, Nagai N, Yamakawa K, Kawakami J, Lijnen HR, Umemura K.

Blood. 2009 Oct 8;114(15):3352-8. Epub 2009 Jul 16.PMID: 19608750 [PubMed - indexed for MEDLINE]Related articles

Effect of tissue inhibitor of matrix metalloproteinases-1 on in vitro and in vivo adipocyte differentiation.

Scroyen I, Cosemans L, Lijnen HR.

Thromb Res. 2009 Nov;124(5):578-83. Epub 2009 Jul 16.PMID: 19608218 [PubMed - in process]Related articles

The tissue-type plasminogen activator story.

Collen D, Lijnen HR.

Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1151-5.PMID: 19605778 [PubMed - indexed for MEDLINE]Related articles

Role of fibrinolysis in obesity and thrombosis.

Lijnen HR.

Thromb Res. 2009;123 Suppl 4:S46-9. Review.PMID: 19303504 [PubMed - indexed for MEDLINE]Related articles

Effect of plasminogen activator inhibitor-1 on adipogenesis in vivo.

Scroyen I, Jacobs F, Cosemans L, De Geest B, Lijnen HR.

Thromb Haemost. 2009 Feb;101(2):388-93.PMID: 19190826 [PubMed - indexed for MEDLINE]Related articles

Obesity and vascular risk.

Lijnen HR.

Hamostaseologie. 2009 Jan;29(1):44-5.PMID: 19151845 [PubMed - indexed for MEDLINE]Related articles

Deficiency of vascular endothelial growth factor-D does not affect murine adipose tissue development.

Lijnen HR, Frederix L, Van Hoef B, Dewerchin M.

Biochem Biophys Res Commun. 2009 Jan 9;378(2):255-8. Epub 2008 Nov 18.PMID: 19022221 [PubMed - indexed for MEDLINE]Related articles

New insights into the molecular mechanisms of the fibrinolytic system.

Rijken DC, Lijnen HR.

J Thromb Haemost. 2009 Jan;7(1):4-13. Epub 2008 Nov 8. Review.PMID: 19017261 [PubMed - indexed for MEDLINE]Related articles

Effect of Vioxx on adipose tissue development in mice with genetically determined obesity.

Lijnen HR.

Thromb Haemost. 2008 Nov;100(5):954. No abstract available. PMID: 18989545 [PubMed - indexed for MEDLINE]Related articles

Antithrombotic effect of clopidogrel in a vena cava thrombosis model in obese mice.

Lijnen HR, Helsen S, Hoylaerts MF.

Thromb Res. 2009 Mar;123(5):763-4. Epub 2008 Nov 5. No abstract available. PMID: 18986687 [PubMed - indexed for MEDLINE]Related articles

Rofecoxib impairs adipose tissue development in a murine model of nutritionally induced obesity.

Lijnen HR, Van Hoef B, Lu HR, Gallacher DJ.

Thromb Haemost. 2008 Aug;100(2):338-42.PMID: 18690356 [PubMed - indexed for MEDLINE]Related articles

Prothrombotic effect of Rofecoxib in a murine venous thrombosis model.

Nagai N, Hoylaerts MF, Gallacher DJ, Lu HR, Lijnen HR.

Thromb Res. 2008;122(5):668-73. Epub 2008 Jun 20.PMID: 18571222 [PubMed - indexed for MEDLINE]Related articles

A functional role of gelatinase A in the development of nutritionally induced obesity in mice.

Van Hul M, Lijnen HR.

J Thromb Haemost. 2008 Jul;6(7):1198-206. Epub 2008 Jul 1.PMID: 18433461 [PubMed - indexed for MEDLINE]Related articles

Role of proteolysis in development of murine adipose tissue.

Christiaens V, Scroyen I, Lijnen HR.

Thromb Haemost. 2008 Feb;99(2):290-4. Review.PMID: 18278177 [PubMed - indexed for MEDLINE]Related articles

Evaluation of matrix metalloproteinases in atherosclerosis using a novel noninvasive imaging approach.

Lancelot E, Amirbekian V, Brigger I, Raynaud JS, Ballet S, David C, Rousseaux O, Le Greneur S, Port M, Lijnen HR, Bruneval P, Michel JB, Ouimet T, Roques B, Amirbekian S, Hyafil F, Vucic E, Aguinaldo JG, Corot C, Fayad ZA.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):425-32. Epub 2008 Feb 7.PMID: 18258820 [PubMed - indexed for MEDLINE]Related articlesFree article

Adverse adipose phenotype and hyperinsulinemia in gravid mice deficient in placental growth factor.

Hemmeryckx B, van Bree R, Van Hoef B, Vercruysse L, Lijnen HR, Verhaeghe J.

Endocrinology. 2008 May;149(5):2176-83. Epub 2008 Feb 7.PMID: 18258676 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity promotes injury induced femoral artery thrombosis in mice.

Nagai N, Hoylaerts MF, Cleuren AC, Van Vlijmen BJ, Lijnen HR.

Thromb Res. 2008;122(4):549-55. Epub 2008 Jan 29.PMID: 18234295 [PubMed - indexed for MEDLINE]Related articles

Angiogenesis and obesity.

Lijnen HR.

Cardiovasc Res. 2008 May 1;78(2):286-93. Epub 2007 Aug 23. Review.PMID: 18006485 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic relapsing experimental allergic encephalomyelitis (CREAE) in plasminogen activator inhibitor-1 knockout mice: the effect of fibrinolysis during neuroinflammation.

East E, Gverić D, Baker D, Pryce G, Lijnen HR, Cuzner ML.

Neuropathol Appl Neurobiol. 2008 Apr;34(2):216-30. Epub 2007 Nov 5.PMID: 17983428 [PubMed - indexed for MEDLINE]Related articles

Deficiency of plasminogen activator inhibitor-2 impairs nutritionally induced murine adipose tissue development.

Lijnen HR, Frederix L, Scroyen I.

J Thromb Haemost. 2007 Nov;5(11):2259-65.PMID: 17958744 [PubMed - indexed for MEDLINE]Related articles

Factor V Leiden mutation is associated with enhanced arterial thrombotic tendency in lean but not in obese mice.

Nagai N, Lijnen HR, Cleuren AC, Rosendaal FR, Van Hoef B, Hoylaerts MF, Van Vlijmen BJ.

Thromb Haemost. 2007 Oct;98(4):858-63.PMID: 17938812 [PubMed - indexed for MEDLINE]Related articles

Chronic plasminogen activator inhibitor-1 (PAI-1) overexpression dampens CD25+ lymphocyte recruitment after lipopolysaccharide endotoxemia in mouse lung.

Poggi M, Paulmyer-Lacroix O, Verdier M, Peiretti F, Bastelica D, Boucraut J, Lijnen HR, Juhan-Vague I, Alessi MC.

J Thromb Haemost. 2007 Dec;5(12):2467-75. Epub 2007 Sep 10.PMID: 17848179 [PubMed - indexed for MEDLINE]Related articles

Inhibition of vascular endothelial growth factor receptor tyrosine kinases impairs adipose tissue development in mouse models of obesity.

Lijnen HR, Van Hoef B, Kemp D, Collen D.

Biochim Biophys Acta. 2007 Sep;1770(9):1369-73. Epub 2007 Jun 15.PMID: 17616257 [PubMed - indexed for MEDLINE]Related articles

Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice.

Suzuki Y, Nagai N, Umemura K, Collen D, Lijnen HR.

J Thromb Haemost. 2007 Aug;5(8):1732-9. Epub 2007 May 21.PMID: 17596135 [PubMed - indexed for MEDLINE]Related articles

Plasminogen activator inhibitor-1 contributes to the deleterious effect of obesity on the outcome of thrombotic ischemic stroke in mice.

Nagai N, Van Hoef B, Lijnen HR.

J Thromb Haemost. 2007 Aug;5(8):1726-31. Epub 2007 May 21.PMID: 17596132 [PubMed - indexed for MEDLINE]Related articles

Deleterious effects of lack of cardiac PAI-1 after coronary occlusion in mice and their pathophysiologic determinants.

Zaman AK, Fujii S, Schneider DJ, Taatjes DJ, Lijnen HR, Sobel BE.

Histochem Cell Biol. 2007 Aug;128(2):135-45. Epub 2007 Jun 19.PMID: 17576591 [PubMed - indexed for MEDLINE]Related articles

A guide to murine fibrinolytic factor structure, function, assays, and genetic alterations.

Matsuo O, Lijnen HR, Ueshima S, Kojima S, Smyth SS.

J Thromb Haemost. 2007 Apr;5(4):680-9. Review.PMID: 17403202 [PubMed - indexed for MEDLINE]Related articles

Deficiency of alpha2-antiplasmin does not affect murine adipose tissue development.

Lijnen HR.

J Thromb Haemost. 2007 Feb;5(2):420-1. No abstract available. PMID: 17269938 [PubMed - indexed for MEDLINE]Related articles

Role of the fibrinolytic and matrix metalloproteinase systems in development of adipose tissue.

Christiaens V, Lijnen HR.

Arch Physiol Biochem. 2006 Oct-Dec;112(4-5):254-9. Review.PMID: 17178599 [PubMed - indexed for MEDLINE]Related articles

Tiplaxtinin impairs nutritionally induced obesity in mice.

Lijnen HR, Alessi MC, Frederix L, Collen D, Juhan-Vague I.

Thromb Haemost. 2006 Dec;96(6):731-7.PMID: 17139366 [PubMed - indexed for MEDLINE]Related articles

On the role of placental growth factor in murine adipogenesis.

Christiaens V, Voros G, Scroyen I, Lijnen HR.

Thromb Res. 2007;120(3):399-405. Epub 2006 Nov 28.PMID: 17134743 [PubMed - indexed for MEDLINE]Related articles

Plasminogen activator inhibitor-1 impairs plasminogen activation-mediated vascular smooth muscle cell apoptosis.

Rossignol P, Anglès-Cano E, Lijnen HR.

Thromb Haemost. 2006 Nov;96(5):665-70.PMID: 17080225 [PubMed - indexed for MEDLINE]Related articlesFree article

No functional role of plasminogen activator inhibitor-1 in murine adipogenesis or adipocyte differentiation.

Scroyen I, Christiaens V, Lijnen HR.

J Thromb Haemost. 2007 Jan;5(1):139-45. Epub 2006 Oct 25.PMID: 17067365 [PubMed - indexed for MEDLINE]Related articles

Expression of aggrecan(ases) during murine preadipocyte differentiation and adipose tissue development.

Voros G, Sandy JD, Collen D, Lijnen HR.

Biochim Biophys Acta. 2006 Dec;1760(12):1837-44. Epub 2006 Aug 26.PMID: 17011710 [PubMed - indexed for MEDLINE]Related articles

Impaired adipose tissue development in mice with inactivation of placental growth factor function.

Lijnen HR, Christiaens V, Scroyen I, Voros G, Tjwa M, Carmeliet P, Collen D.

Diabetes. 2006 Oct;55(10):2698-704.PMID: 17003333 [PubMed - indexed for MEDLINE]Related articlesFree article

Haemostasis.

Arnout J, Hoylaerts MF, Lijnen HR.

Handb Exp Pharmacol. 2006;(176 Pt 2):1-41. Review.PMID: 17001771 [PubMed - indexed for MEDLINE]Related articles

Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice.

Renckens R, Roelofs JJ, Florquin S, de Vos AF, Pater JM, Lijnen HR, Carmeliet P, van 't Veer C, van der Poll T.

J Immunol. 2006 Jul 15;177(2):1189-96.PMID: 16818777 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of placental growth factor in glucose metabolism.

Voros G, Lijnen HR.

J Thromb Haemost. 2006 Sep;4(9):2098-9. No abstract available. PMID: 16796728 [PubMed - indexed for MEDLINE]Related articles

Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in mice does not affect adipogenesis or adipose tissue development.

Demeulemeester D, Scroyen I, Voros G, Snoeys J, De Geest B, Collen D, Lijnen HR.

Thromb Haemost. 2006 Jun;95(6):1019-24.PMID: 16732382 [PubMed - indexed for MEDLINE]Related articles

Generation of a stable activated thrombin activable fibrinolysis inhibitor variant.

Ceresa E, Van de Borne K, Peeters M, Lijnen HR, Declerck PJ, Gils A.

J Biol Chem. 2006 Jun 9;281(23):15878-83. Epub 2006 Apr 4.PMID: 16595693 [PubMed - indexed for MEDLINE]Related articlesFree article

Impairment of adipose tissue development by hypoxia is not mediated by plasminogen activator inhibitor-1.

Semeraro F, Voros G, Collen D, Lijnen HR.

Thromb Haemost. 2006 Jan;95(1):174-81.PMID: 16543977 [PubMed - indexed for MEDLINE]Related articles

Dual effect of apolipoprotein(a) on plasmin(ogen)-induced apoptosis through modulation of cell detachment of adherent cells.

Ho-Tin-Noé B, Meilhac O, Rossignol P, Lijnen HR, Anglés-Cano E.

Thromb Haemost. 2006 Jan;95(1):142-50.PMID: 16543973 [PubMed - indexed for MEDLINE]Related articles

Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis.

Renckens R, Roelofs JJ, Florquin S, de Vos AF, Lijnen HR, van't Veer C, van der Poll T.

J Immunol. 2006 Mar 15;176(6):3735-41.PMID: 16517742 [PubMed - indexed for MEDLINE]Related articlesFree article