PubMed

Hypothalamic-pituitary-adrenal axis activation in obstructive sleep apnea: the effect of continuous positive airway pressure therapy.

Henley DE, Russell GM, Douthwaite JA, Wood SA, Buchanan F, Gibson R, Woltersdorf WW, Catterall JR, Lightman SL.

J Clin Endocrinol Metab. 2009 Nov;94(11):4234-42. Epub 2009 Oct 9.PMID: 19820009 [PubMed - in process]Related articles

Characterization of conserved tandem donor sites and intronic motifs required for alternative splicing in corticosteroid receptor genes.

Rivers C, Flynn A, Qian X, Matthews L, Lightman S, Ray D, Norman M.

Endocrinology. 2009 Nov;150(11):4958-67. Epub 2009 Oct 9.PMID: 19819975 [PubMed - indexed for MEDLINE]Related articles

Emotional sensitivity for motherhood: Late pregnancy is associated with enhanced accuracy to encode emotional faces.

Pearson RM, Lightman SL, Evans J.

Horm Behav. 2009 Nov;56(5):557-63. Epub 2009 Sep 26.PMID: 19786033 [PubMed - in process]Related articles

Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression.

Gardner KL, Hale MW, Lightman SL, Plotsky PM, Lowry CA.

Brain Res. 2009 Sep 23. [Epub ahead of print]PMID: 19781533 [PubMed - as supplied by publisher]Related articles

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription.

Stavreva DA, Wiench M, John S, Conway-Campbell BL, McKenna MA, Pooley JR, Johnson TA, Voss TC, Lightman SL, Hager GL.

Nat Cell Biol. 2009 Sep;11(9):1093-102. Epub 2009 Aug 16.PMID: 19684579 [PubMed - indexed for MEDLINE]Related articles

Depressive symptoms in early pregnancy disrupt attentional processing of infant emotion.

Pearson RM, Cooper RM, Penton-Voak IS, Lightman SL, Evans J.

Psychol Med. 2009 Aug 12:1-11. [Epub ahead of print]PMID: 19671214 [PubMed - as supplied by publisher]Related articles

Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus.

Gardner KL, Hale MW, Oldfield S, Lightman SL, Plotsky PM, Lowry CA.

Neuroscience. 2009 Nov 10;163(4):991-1001. Epub 2009 Jul 30.PMID: 19647049 [PubMed - in process]Related articles

Plasma apelin levels in obstructive sleep apnea and the effect of continuous positive airway pressure therapy.

Henley DE, Buchanan F, Gibson R, Douthwaite JA, Wood SA, Woltersdorf WW, Catterall JR, Lightman SL.

J Endocrinol. 2009 Oct;203(1):181-8. Epub 2009 Jul 30.PMID: 19643928 [PubMed - indexed for MEDLINE]Related articles

A glucocorticoid sensitive biphasic rhythm of testosterone secretion.

Waite E, Kershaw Y, Spiga F, Lightman SL.

J Neuroendocrinol. 2009 Sep;21(9):737-41. Epub 2009 Jul 7.PMID: 19602101 [PubMed - in process]Related articles

Ocular features in neurosarcoidosis.

Menezo V, Lobo A, Yeo TK, du Bois RM, Lightman S.

Ocul Immunol Inflamm. 2009 May-Jun;17(3):170-8.PMID: 19585359 [PubMed - indexed for MEDLINE]Related articles

Neonatal lipopolysaccharide exposure delays puberty and alters hypothalamic Kiss1 and Kiss1r mRNA expression in the female rat.

Knox AM, Li XF, Kinsey-Jones JS, Wilkinson ES, Wu XQ, Cheng YS, Milligan SR, Lightman SL, O'Byrne KT.

J Neuroendocrinol. 2009 Aug;21(8):683-9. Epub 2009 Jun 4.PMID: 19500221 [PubMed - indexed for MEDLINE]Related articles

Distinct, time-dependent effects of voluntary exercise on circadian and ultradian rhythms and stress responses of free corticosterone in the rat hippocampus.

Droste SK, Collins A, Lightman SL, Linthorst AC, Reul JM.

Endocrinology. 2009 Sep;150(9):4170-9. Epub 2009 May 28.PMID: 19477935 [PubMed - indexed for MEDLINE]Related articles

Reversal of the hypothalamo-pituitary-adrenal response to oestrogens around puberty.

Evuarherhe O, Leggett J, Waite E, Kershaw Y, Lightman S.

J Endocrinol. 2009 Aug;202(2):279-85. Epub 2009 May 27.PMID: 19474059 [PubMed - indexed for MEDLINE]Related articles

Rituximab is effective in the treatment of refractory ophthalmic Wegener's granulomatosis.

Taylor SR, Salama AD, Joshi L, Pusey CD, Lightman SL.

Arthritis Rheum. 2009 May;60(5):1540-7.PMID: 19404964 [PubMed - indexed for MEDLINE]Related articles

Organizational role for pubertal androgens on adult hypothalamic-pituitary-adrenal sensitivity to testosterone in the male rat.

Evuarherhe O, Leggett JD, Waite EJ, Kershaw YM, Atkinson HC, Lightman SL.

J Physiol. 2009 Jun 15;587(Pt 12):2977-85. Epub 2009 Apr 29.PMID: 19403614 [PubMed - indexed for MEDLINE]Related articles

Outcome of raised intraocular pressure in uveitic eyes with and without a corticosteroid-induced hypertensive response.

Sallam A, Sheth HG, Habot-Wilner Z, Lightman S.

Am J Ophthalmol. 2009 Aug;148(2):207-213.e1. Epub 2009 Apr 29.PMID: 19403113 [PubMed - indexed for MEDLINE]Related articles

Recent developments in the treatment of uveitis: an update.

Lyon F, Gale RP, Lightman S.

Expert Opin Investig Drugs. 2009 May;18(5):609-16.PMID: 19388878 [PubMed - in process]Related articles

Dose-dependent effects of corticosterone on nuclear glucocorticoid receptors and their binding to DNA in the brain and pituitary of the rat.

Spiga F, Lightman SL.

Brain Res. 2009 Oct 13;1293:101-7. Epub 2009 Feb 12.PMID: 19368803 [PubMed - indexed for MEDLINE]Related articles

Intraocular methotrexate in the treatment of uveitis and uveitic cystoid macular edema.

Taylor SR, Habot-Wilner Z, Pacheco P, Lightman SL.

Ophthalmology. 2009 Apr;116(4):797-801.PMID: 19344827 [PubMed - indexed for MEDLINE]Related articles

Development of an automated blood sampling system for use in humans.

Henley DE, Leendertz JA, Russell GM, Wood SA, Taheri S, Woltersdorf WW, Lightman SL.

J Med Eng Technol. 2009;33(3):199-208.PMID: 19340690 [PubMed - indexed for MEDLINE]Related articles

Prednisolone suppression test in depression: prospective study of the role of HPA axis dysfunction in treatment resistance.

Juruena MF, Pariante CM, Papadopoulos AS, Poon L, Lightman S, Cleare AJ.

Br J Psychiatry. 2009 Apr;194(4):342-9.PMID: 19336786 [PubMed - indexed for MEDLINE]Related articles

So you want to be ... an ophthalmologist.

Hale SL, Lightman S.

Br J Hosp Med (Lond). 2009 Feb;70(2):M32. No abstract available. PMID: 19294820 [PubMed - indexed for MEDLINE]Related articles

Renal & ocular targets for therapy in Wegener's granulomatosis.

Joshi L, Hamour S, Salama AD, Pusey CD, Lightman S, Taylor SR.

Inflamm Allergy Drug Targets. 2009 Mar;8(1):70-9. Review.PMID: 19275695 [PubMed - indexed for MEDLINE]Related articles

A case of optic neuropathy after short-term linezolid use in a patient with acute lymphocytic leukemia.

Joshi L, Taylor SR, Large O, Yacoub S, Lightman S.

Clin Infect Dis. 2009 Apr 1;48(7):e73-4.PMID: 19231981 [PubMed - indexed for MEDLINE]Related articles

Vasopressin does not mediate hypersensitivity of the hypothalamic pituitary adrenal axis during chronic stress.

Chen J, Young S, Subburaju S, Sheppard J, Kiss A, Atkinson H, Wood S, Lightman S, Serradeil-Le Gal C, Aguilera G.

Ann N Y Acad Sci. 2008 Dec;1148:349-59.PMID: 19120128 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of hypothalamic kisspeptin and its receptor, Kiss1r, mRNA expression is associated with stress-induced suppression of luteinising hormone secretion in the female rat.

Kinsey-Jones JS, Li XF, Knox AM, Wilkinson ES, Zhu XL, Chaudhary AA, Milligan SR, Lightman SL, O'Byrne KT.

J Neuroendocrinol. 2009 Jan;21(1):20-9.PMID: 19094090 [PubMed - indexed for MEDLINE]Related articles

The ultradian and circadian rhythms of free corticosterone in the brain are not affected by gender: an in vivo microdialysis study in Wistar rats.

Droste SK, de Groote L, Lightman SL, Reul JM, Linthorst AC.

J Neuroendocrinol. 2009 Feb;21(2):132-40.PMID: 19076270 [PubMed - indexed for MEDLINE]Related articles

That warm fuzzy feeling: brain serotonergic neurons and the regulation of emotion.

Lowry CA, Lightman SL, Nutt DJ.

J Psychopharmacol. 2009 Jun;23(4):392-400. Epub 2008 Dec 12. Review.PMID: 19074539 [PubMed - indexed for MEDLINE]Related articles

Effect of vasopressin 1b receptor blockade on the hypothalamic-pituitary-adrenal response of chronically stressed rats to a heterotypic stressor.

Spiga F, Harrison LR, MacSweeney CP, Thomson FJ, Craighead M, Lightman SL.

J Endocrinol. 2009 Mar;200(3):285-91. Epub 2008 Dec 12.PMID: 19074473 [PubMed - indexed for MEDLINE]Related articles

A role for the medial preoptic area in CGRP-induced suppression of pulsatile LH secretion in the female rat.

Li XF, Kinsey-Jones JS, Bowe JE, Wilkinson ES, Brain SD, Lightman SL, O'Byrne KT.

Stress. 2009;12(3):259-67.PMID: 19051122 [PubMed - indexed for MEDLINE]Related articles

Blockade of the V(1b) receptor reduces ACTH, but not corticosterone secretion induced by stress without affecting basal hypothalamic-pituitary-adrenal axis activity.

Spiga F, Harrison LR, Wood S, Knight DM, MacSweeney CP, Thomson F, Craighead M, Lightman SL.

J Endocrinol. 2009 Mar;200(3):273-83. Epub 2008 Nov 13.PMID: 19008333 [PubMed - indexed for MEDLINE]Related articles

Fluoxetine inhibits corticotropin-releasing factor (CRF)-induced behavioural responses in rats.

Lowry CA, Hale MW, Plant A, Windle RJ, Shanks N, Wood SA, Ingram CD, Renner KJ, Lightman SL, Summers CH.

Stress. 2009;12(3):225-39.PMID: 18951247 [PubMed - indexed for MEDLINE]Related articles

Interferon-alpha in the management of patients with Behçet's disease.

Yang DS, Taylor SR, Lightman SL.

Br J Hosp Med (Lond). 2008 Oct;69(10):575-9. Review. No abstract available. PMID: 18949947 [PubMed - indexed for MEDLINE]Related articles

The HPA axis in major depression: classical theories and new developments.

Pariante CM, Lightman SL.

Trends Neurosci. 2008 Sep;31(9):464-8. Epub 2008 Jul 31. Review.PMID: 18675469 [PubMed - indexed for MEDLINE]Related articles

Women with diarrhoea-predominant irritable bowel syndrome show an increased pressure response to 35% carbon dioxide stress challenge.

Shufflebotham J, Wetherell MA, Hince D, Hood S, Lightman S, Nutt D, Probert C, Potokar J.

Stress. 2009;12(1):30-6.PMID: 18609306 [PubMed - indexed for MEDLINE]Related articles

The neuroendocrinology of stress: a never ending story.

Lightman SL.

J Neuroendocrinol. 2008 Jun;20(6):880-4. Review.PMID: 18601712 [PubMed - indexed for MEDLINE]Related articles

The role of corticotrophin-releasing hormone receptors in the calcitonin gene-related peptide-induced suppression of pulsatile luteinising hormone secretion in the female rat.

Bowe JE, Li XF, Kinsey-Jones JS, Brain SD, Lightman SL, O'Byrne KT.

Stress. 2008;11(4):312-9.PMID: 18574791 [PubMed - indexed for MEDLINE]Related articles

Intracellular cytokine profiles and T cell activation in pulmonary sarcoidosis.

Hill TA, Lightman S, Pantelidis P, Abdallah A, Spagnolo P, du Bois RM.

Cytokine. 2008 Jun;42(3):289-92. Epub 2008 May 15.PMID: 18485728 [PubMed - indexed for MEDLINE]Related articles

Infliximab therapy for aggressive mooren ulceration.

Saw VP, Cornelius N, Salama AD, Pusey C, Lightman SL.

Arch Ophthalmol. 2008 May;126(5):734. No abstract available. PMID: 18474792 [PubMed - indexed for MEDLINE]Related articles

Use of ocular hypotensive prostaglandin analogues in patients with uveitis: does their use increase anterior uveitis and cystoid macular oedema?

Chang JH, McCluskey P, Missotten T, Ferrante P, Jalaludin B, Lightman S.

Br J Ophthalmol. 2008 Jul;92(7):916-21. Epub 2008 May 6.PMID: 18460537 [PubMed - indexed for MEDLINE]Related articles

Corticosterone levels in the brain show a distinct ultradian rhythm but a delayed response to forced swim stress.

Droste SK, de Groote L, Atkinson HC, Lightman SL, Reul JM, Linthorst AC.

Endocrinology. 2008 Jul;149(7):3244-53. Epub 2008 Mar 20.PMID: 18356272 [PubMed - indexed for MEDLINE]Related articlesFree article

Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor.

Atkinson HC, Wood SA, Castrique ES, Kershaw YM, Wiles CC, Lightman SL.

Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1011-22. Epub 2008 Mar 18.PMID: 18349112 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of the glucocorticoid receptor with the chromatin landscape.

John S, Sabo PJ, Johnson TA, Sung MH, Biddie SC, Lightman SL, Voss TC, Davis SR, Meltzer PS, Stamatoyannopoulos JA, Hager GL.

Mol Cell. 2008 Mar 14;29(5):611-24.PMID: 18342607 [PubMed - indexed for MEDLINE]Related articles

The significance of glucocorticoid pulsatility.

Lightman SL, Wiles CC, Atkinson HC, Henley DE, Russell GM, Leendertz JA, McKenna MA, Spiga F, Wood SA, Conway-Campbell BL.

Eur J Pharmacol. 2008 Apr 7;583(2-3):255-62. Epub 2008 Feb 9. Review.PMID: 18339373 [PubMed - indexed for MEDLINE]Related articles

Genetic background influences the behavioural and molecular consequences of neurokinin-1 receptor knockout.

McCutcheon JE, Fisher AS, Guzdar E, Wood SA, Lightman SL, Hunt SP.

Eur J Neurosci. 2008 Feb;27(3):683-90.PMID: 18279320 [PubMed - indexed for MEDLINE]Related articles

Short-term safety and efficacy of intravitreal triamcinolone acetonide for uveitic macular edema in children.

Sallam A, Comer RM, Chang JH, Grigg JR, Andrews R, McCluskey PJ, Lightman S.

Arch Ophthalmol. 2008 Feb;126(2):200-5.PMID: 18268210 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release.

Spiga F, Harrison LR, Wood SA, MacSweeney CP, Thomson FJ, Craighead M, Grassie M, Lightman SL.

J Endocrinol. 2008 Feb;196(2):323-30.PMID: 18252955 [PubMed - indexed for MEDLINE]Related articlesFree article

Intraocular delivery of anti-infective drugs-bacterial, viral, fungal and parasitic.

Sallam A, Jayakumar S, Lightman S.

Recent Pat Antiinfect Drug Discov. 2008 Jan;3(1):53-63. Review.PMID: 18221186 [PubMed - indexed for MEDLINE]Related articles

Treating the ocular component of allergic rhinoconjunctivitis and related eye disorders.

Bielory L, Katelaris CH, Lightman S, Naclerio RM.

MedGenMed. 2007 Aug 15;9(3):35. Review.PMID: 18092041 [PubMed - indexed for MEDLINE]Related articlesFree article

The potential of newer immunomodulating drugs in the treatment of uveitis: a review.

Salzmann J, Lightman S.

BioDrugs. 2000 Jun;13(6):397-408.PMID: 18034546 [PubMed - in process]Related articles