PubMed

Ancrod in Acute Ischemic Stroke. Results of 500 Subjects Beginning Treatment Within 6 Hours of Stroke Onset in the Ancrod Stroke Program.

Levy DE, Del Zoppo GJ, Demaerschalk BM, Demchuk AM, Diener HC, Howard G, Kaste M, Pancioli AM, Spatareanu C, Wasiewski WW.

Stroke. 2009 Oct 29. [Epub ahead of print]PMID: 19875736 [PubMed - as supplied by publisher]Related articles

Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression.

Ranger JJ, Levy DE, Shahalizadeh S, Hallett M, Muller WJ.

Cancer Res. 2009 Sep 1;69(17):6823-30. Epub 2009 Aug 18.PMID: 19690134 [PubMed - indexed for MEDLINE]Related articles

Reduction of Stat3 activity attenuates HIV-induced kidney injury.

Feng X, Lu TC, Chuang PY, Fang W, Ratnam K, Xiong H, Ouyang X, Shen Y, Levy DE, Hyink D, Klotman M, D'Agati V, Iyengar R, Klotman PE, He JC.

J Am Soc Nephrol. 2009 Oct;20(10):2138-46. Epub 2009 Jul 16.PMID: 19608706 [PubMed - indexed for MEDLINE]Related articles

Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells.

O'Malley JT, Sehra S, Thieu VT, Yu Q, Chang HC, Stritesky GL, Nguyen ET, Mathur AN, Levy DE, Kaplan MH.

Immunology. 2009 Aug;127(4):587-95.PMID: 19604309 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.

Gough DJ, Corlett A, Schlessinger K, Wegrzyn J, Larner AC, Levy DE.

Science. 2009 Jun 26;324(5935):1713-6.PMID: 19556508 [PubMed - indexed for MEDLINE]Related articles

Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials.

Saver JL, Albers GW, Dunn B, Johnston KC, Fisher M; STAIR VI Consortium.

Stroke. 2009 Jul;40(7):2594-600. Epub 2009 May 28.PMID: 19478212 [PubMed - indexed for MEDLINE]Related articles

Guidelines for genetic risk assessment of hereditary breast and ovarian cancer: early disagreements and low utilization.

Levy DE, Garber JE, Shields AE.

J Gen Intern Med. 2009 Jul;24(7):822-8. Epub 2009 May 20.PMID: 19455369 [PubMed - in process]Related articles

c-Maf regulates IL-10 expression during Th17 polarization.

Xu J, Yang Y, Qiu G, Lal G, Wu Z, Levy DE, Ochando JC, Bromberg JS, Ding Y.

J Immunol. 2009 May 15;182(10):6226-36.PMID: 19414776 [PubMed - indexed for MEDLINE]Related articles

Clinical course and outcome in children with acute lymphoblastic leukemia and asparaginase-associated pancreatitis.

Kearney SL, Dahlberg SE, Levy DE, Voss SD, Sallan SE, Silverman LB.

Pediatr Blood Cancer. 2009 Aug;53(2):162-7.PMID: 19405141 [PubMed - indexed for MEDLINE]Related articles

Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy.

Lu TC, Wang ZH, Feng X, Chuang PY, Fang W, Shen Y, Levy DE, Xiong H, Chen N, He JC.

Kidney Int. 2009 Jul;76(1):63-71. Epub 2009 Apr 8.PMID: 19357722 [PubMed - indexed for MEDLINE]Related articles

Hyperfibrinogenemia and functional outcome from acute ischemic stroke.

del Zoppo GJ, Levy DE, Wasiewski WW, Pancioli AM, Demchuk AM, Trammel J, Demaerschalk BM, Kaste M, Albers GW, Ringelstein EB.

Stroke. 2009 May;40(5):1687-91. Epub 2009 Mar 19.PMID: 19299642 [PubMed - indexed for MEDLINE]Related articlesFree article

The natural history of light smokers: a population-based cohort study.

Levy DE, Biener L, Rigotti NA.

Nicotine Tob Res. 2009 Feb;11(2):156-63. Epub 2009 Mar 5.PMID: 19264862 [PubMed - indexed for MEDLINE]Related articles

Update of the stroke therapy academic industry roundtable preclinical recommendations.

Fisher M, Feuerstein G, Howells DW, Hurn PD, Kent TA, Savitz SI, Lo EH; STAIR Group.

Stroke. 2009 Jun;40(6):2244-50. Epub 2009 Feb 26. Review.PMID: 19246690 [PubMed - indexed for MEDLINE]Related articles

IL-21 mediates suppressive effects via its induction of IL-10.

Spolski R, Kim HP, Zhu W, Levy DE, Leonard WJ.

J Immunol. 2009 Mar 1;182(5):2859-67.PMID: 19234181 [PubMed - indexed for MEDLINE]Related articles

Ancrod for acute ischemic stroke: a new dosing regimen derived from analysis of prior ancrod stroke studies.

Levy DE, Trammel J, Wasiewski WW; Ancrod Stroke Program (ASP) Study Team.

J Stroke Cerebrovasc Dis. 2009 Jan;18(1):23-7.PMID: 19110140 [PubMed - indexed for MEDLINE]Related articles

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation.

Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger EP, Reid SP, Levy DE, Bromberg JS.

J Immunol. 2009 Jan 1;182(1):259-73.PMID: 19109157 [PubMed - indexed for MEDLINE]Related articles

Nucleoporin levels regulate cell cycle progression and phase-specific gene expression.

Chakraborty P, Wang Y, Wei JH, van Deursen J, Yu H, Malureanu L, Dasso M, Forbes DJ, Levy DE, Seemann J, Fontoura BM.

Dev Cell. 2008 Nov;15(5):657-67.PMID: 19000832 [PubMed - indexed for MEDLINE]Related articles

IFNgamma signaling-does it mean JAK-STAT?

Gough DJ, Levy DE, Johnstone RW, Clarke CJ.

Cytokine Growth Factor Rev. 2008 Oct-Dec;19(5-6):383-94. Epub 2008 Oct 16. Review.PMID: 18929502 [PubMed - indexed for MEDLINE]Related articles

Primary care physicians' willingness to offer a new genetic test to tailor smoking treatment, according to test characteristics.

Shields AE, Levy DE, Blumenthal D, Currivan D, McGinn-Shapiro M, Weiss KB, Yucel R, Lerman C.

Nicotine Tob Res. 2008 Jun;10(6):1037-45.PMID: 18584467 [PubMed - indexed for MEDLINE]Related articles

Electronic health records in ambulatory care--a national survey of physicians.

DesRoches CM, Campbell EG, Rao SR, Donelan K, Ferris TG, Jha A, Kaushal R, Levy DE, Rosenbaum S, Shields AE, Blumenthal D.

N Engl J Med. 2008 Jul 3;359(1):50-60. Epub 2008 Jun 18.PMID: 18565855 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential use of available genetic tests among primary care physicians in the United States: results of a national survey.

Shields AE, Burke W, Levy DE.

Genet Med. 2008 Jun;10(6):404-14.PMID: 18496223 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk stratification for biochemical recurrence in men with positive surgical margins or extracapsular disease after radical prostatectomy: results from the SEARCH database.

Jayachandran J, Bañez LL, Levy DE, Aronson WJ, Terris MK, Presti JC Jr, Amling CL, Kane CJ, Freedland SJ; SEARCH Database Study Group.

J Urol. 2008 May;179(5):1791-6; discussion 1796. Epub 2008 Mar 17. Erratum in: J Urol. 2008 Nov;180(5):2263. PMID: 18343426 [PubMed - indexed for MEDLINE]Related articles

Aryl-indolyl maleimides as inhibitors of CaMKIIdelta. Part 3: Importance of the indole orientation.

Lu Q, Chen Z, Perumattam J, Wang DX, Liang W, Xu YJ, Do S, Bonaga L, Higaki J, Dong H, Liclican A, Sideris S, Laney M, Dugar S, Mavunkel B, Levy DE.

Bioorg Med Chem Lett. 2008 Apr 1;18(7):2399-403. Epub 2008 Mar 4.PMID: 18337095 [PubMed - indexed for MEDLINE]Related articles

Aryl-indolyl maleimides as inhibitors of CaMKIIdelta. Part 2: SAR of the amine tether.

Levy DE, Wang DX, Lu Q, Chen Z, Perumattam J, Xu YJ, Higaki J, Dong H, Liclican A, Laney M, Mavunkel B, Dugar S.

Bioorg Med Chem Lett. 2008 Apr 1;18(7):2395-8. Epub 2008 Mar 4.PMID: 18334295 [PubMed - indexed for MEDLINE]Related articles

Aryl-indolyl maleimides as inhibitors of CaMKIIdelta. Part 1: SAR of the aryl region.

Levy DE, Wang DX, Lu Q, Chen Z, Perumattam J, Xu YJ, Liclican A, Higaki J, Dong H, Laney M, Mavunkel B, Dugar S.

Bioorg Med Chem Lett. 2008 Apr 1;18(7):2390-4. Epub 2008 Mar 4.PMID: 18334294 [PubMed - indexed for MEDLINE]Related articles

Pyrimidine-based inhibitors of CaMKIIdelta.

Mavunkel B, Xu YJ, Goyal B, Lim D, Lu Q, Chen Z, Wang DX, Higaki J, Chakraborty I, Liclican A, Sideris S, Laney M, Delling U, Catalano R, Higgins LS, Wang H, Wang J, Feng Y, Dugar S, Levy DE.

Bioorg Med Chem Lett. 2008 Apr 1;18(7):2404-8. Epub 2008 Mar 4.PMID: 18334293 [PubMed - indexed for MEDLINE]Related articles

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway.

de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A.

Genes Dev. 2008 Feb 15;22(4):449-62. Epub 2008 Feb 7.PMID: 18258752 [PubMed - indexed for MEDLINE]Related articlesFree article

Primary care physicians' concerns about offering a genetic test to tailor smoking cessation treatment.

Levy DE, Youatt EJ, Shields AE.

Genet Med. 2007 Dec;9(12):842-9.PMID: 18091434 [PubMed - indexed for MEDLINE]Related articles

Use of nicotine replacement therapy to reduce or delay smoking but not to quit: prevalence and association with subsequent cessation efforts.

Levy DE, Thorndike AN, Biener L, Rigotti NA.

Tob Control. 2007 Dec;16(6):384-9.PMID: 18048614 [PubMed - indexed for MEDLINE]Related articlesFree article

The zinc finger antiviral protein acts synergistically with an interferon-induced factor for maximal activity against alphaviruses.

MacDonald MR, Machlin ES, Albin OR, Levy DE.

J Virol. 2007 Dec;81(24):13509-18. Epub 2007 Oct 10.PMID: 17928353 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT3 signaling and the hyper-IgE syndrome.

Levy DE, Loomis CA.

N Engl J Med. 2007 Oct 18;357(16):1655-8. Epub 2007 Sep 19. No abstract available. PMID: 17881746 [PubMed - indexed for MEDLINE]Related articles

Adoption of health information technology in community health centers: results of a national survey.

Shields AE, Shin P, Leu MG, Levy DE, Betancourt RM, Hawkins D, Proser M.

Health Aff (Millwood). 2007 Sep-Oct;26(5):1373-83.PMID: 17848448 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes and Alzheimer's disease: from common pathologies to potential new therapeutics.

Levy DE.

J Diabetes Sci Technol. 2007 Jul;1(4):590-4.PMID: 19885123 [PubMed - in process]Free article

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.

Zhou L, Ivanov II, Spolski R, Min R, Shenderov K, Egawa T, Levy DE, Leonard WJ, Littman DR.

Nat Immunol. 2007 Sep;8(9):967-74. Epub 2007 Jun 20.PMID: 17581537 [PubMed - indexed for MEDLINE]Related articles

Restricted tissue tropism and acquired resistance to Sindbis viral vector expression in the absence of innate and adaptive immunity.

Tseng JC, Zheng Y, Yee H, Levy DE, Meruelo D.

Gene Ther. 2007 Aug;14(15):1166-74. Epub 2007 May 17.PMID: 17508007 [PubMed - indexed for MEDLINE]Related articles

JAK-STAT signaling: from interferons to cytokines.

Schindler C, Levy DE, Decker T.

J Biol Chem. 2007 Jul 13;282(28):20059-63. Epub 2007 May 14. Review. No abstract available. PMID: 17502367 [PubMed - indexed for MEDLINE]Related articlesFree article

EGFR dinucleotide repeat polymorphism as a prognostic indicator in non-small cell lung cancer.

Dubey S, Stephenson P, Levy DE, Miller JA, Keller SM, Schiller JH, Johnson DH, Kolesar JM; Eastern Cooperative Oncology Group.

J Thorac Oncol. 2006 Jun;1(5):406-12.PMID: 17409891 [PubMed - indexed for MEDLINE]Related articles

Stat3 and Stat4 direct development of IL-17-secreting Th cells.

Mathur AN, Chang HC, Zisoulis DG, Stritesky GL, Yu Q, O'Malley JT, Kapur R, Levy DE, Kansas GS, Kaplan MH.

J Immunol. 2007 Apr 15;178(8):4901-7.PMID: 17404271 [PubMed - indexed for MEDLINE]Related articlesFree article

A phase II trial of perifosine in locally advanced, unresectable, or metastatic pancreatic adenocarcinoma.

Marsh Rde W, Rocha Lima CM, Levy DE, Mitchell EP, Rowland KM Jr, Benson AB 3rd.

Am J Clin Oncol. 2007 Feb;30(1):26-31.PMID: 17278891 [PubMed - indexed for MEDLINE]Related articles

Influenza virus targets the mRNA export machinery and the nuclear pore complex.

Satterly N, Tsai PL, van Deursen J, Nussenzveig DR, Wang Y, Faria PA, Levay A, Levy DE, Fontoura BM.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1853-8. Epub 2007 Jan 31.PMID: 17267598 [PubMed - indexed for MEDLINE]Related articlesFree article

The molecular basis of IL-21-mediated proliferation.

Zeng R, Spolski R, Casas E, Zhu W, Levy DE, Leonard WJ.

Blood. 2007 May 15;109(10):4135-42. Epub 2007 Jan 18.PMID: 17234735 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of Stat3 transcriptional activity by the conserved LPMSP motif for OSM and IL-6 signaling.

Sun W, Snyder M, Levy DE, Zhang JJ.

FEBS Lett. 2006 Oct 30;580(25):5880-4. Epub 2006 Oct 2.PMID: 17027757 [PubMed - indexed for MEDLINE]Related articles

Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukemia.

Moghrabi A, Levy DE, Asselin B, Barr R, Clavell L, Hurwitz C, Samson Y, Schorin M, Dalton VK, Lipshultz SE, Neuberg DS, Gelber RD, Cohen HJ, Sallan SE, Silverman LB.

Blood. 2007 Feb 1;109(3):896-904. Epub 2006 Sep 26.PMID: 17003366 [PubMed - indexed for MEDLINE]Related articlesFree article

Employer-sponsored insurance coverage of smoking cessation treatments.

Levy DE.

Am J Manag Care. 2006 Sep;12(9):553-62.PMID: 16961444 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear and cytoplasmic mRNA quantification by SYBR green based real-time RT-PCR.

Wang Y, Zhu W, Levy DE.

Methods. 2006 Aug;39(4):356-62.PMID: 16893657 [PubMed - indexed for MEDLINE]Related articles

C. elegans STAT: evolution of a regulatory switch.

Wang Y, Levy DE.

FASEB J. 2006 Aug;20(10):1641-52.PMID: 16873887 [PubMed - indexed for MEDLINE]Related articlesFree article

A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200.

Giantonio BJ, Levy DE, O'dwyer PJ, Meropol NJ, Catalano PJ, Benson AB 3rd; Eastern Cooperative Oncology Group.

Ann Oncol. 2006 Sep;17(9):1399-403. Epub 2006 Jul 27.PMID: 16873427 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT1 acts as a tumor promoter for leukemia development.

Kovacic B, Stoiber D, Moriggl R, Weisz E, Ott RG, Kreibich R, Levy DE, Beug H, Freissmuth M, Sexl V.

Cancer Cell. 2006 Jul;10(1):77-87.PMID: 16843267 [PubMed - indexed for MEDLINE]Related articles

STAT3 positively regulates an early step in B-cell development.

Chou WC, Levy DE, Lee CK.

Blood. 2006 Nov 1;108(9):3005-11. Epub 2006 Jul 6.PMID: 16825489 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT3: a multifaceted oncogene.

Levy DE, Inghirami G.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10151-2. Epub 2006 Jun 26. No abstract available. PMID: 16801534 [PubMed - indexed for MEDLINE]Related articlesFree article