PubMed

Context and disease when disease risk is low.

Lynch KF, Subramanian SV, Ohlsson H, Chaix B, Lernmark A, Merlo J.

J Epidemiol Community Health. 2009 Oct 14. [Epub ahead of print]PMID: 19833608 [PubMed - as supplied by publisher]Related articles

Comparison of three assays for the detection of GAD65Ab-specific anti-idiotypic antibodies.

Oak S, Radtke J, Landin-Olsson M, Törn C, Lernmark A, Hampe CS.

J Immunol Methods. 2009 Dec 31;351(1-2):55-61. Epub 2009 Sep 23.PMID: 19781546 [PubMed - in process]Related articles

Sequence variation and expression of the Gimap gene family in the BB rat.

Rutledge EA, Fuller JM, Van Yserloo B, Moralejo DH, Ettinger RA, Gaur P, Hoehna JL, Peterson MR, Jensen R, Kwitek AE, Lernmark A.

Exp Diabetes Res. 2009;2009:835650. Epub 2009 May 3.PMID: 19421422 [PubMed - indexed for MEDLINE]Related articlesFree article

GAD65 vaccination: 5 years of follow-up in a randomised dose-escalating study in adult-onset autoimmune diabetes.

Agardh CD, Lynch KF, Palmér M, Link K, Lernmark A.

Diabetologia. 2009 Jul;52(7):1363-8. Epub 2009 Apr 30.PMID: 19404608 [PubMed - indexed for MEDLINE]Related articles

Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene.

Fuller JM, Bogdani M, Tupling TD, Jensen RA, Pefley R, Manavi S, Cort L, Blankenhorn EP, Mordes JP, Lernmark A, Kwitek AE.

Physiol Genomics. 2009 Jun 10;38(1):89-97. Epub 2009 Apr 7.PMID: 19351909 [PubMed - indexed for MEDLINE]Related articles

The type 1 diabetes protective HLA DQB1*0602 allele is less frequent in gestational diabetes mellitus.

Papadopoulou A, Lynch KF, Shaat N, Nilsson A, Lernmark B, Berntorp K, Ivarsson SA, Agardh CD, Lernmark A; DiPiS Study Group.

Diabetologia. 2009 Jul;52(7):1339-42. Epub 2009 Apr 4.PMID: 19347328 [PubMed - indexed for MEDLINE]Related articles

Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus.

Mordes JP, Cort L, Norowski E, Leif J, Fuller JM, Lernmark A, Greiner DL, Blankenhorn EP.

Mamm Genome. 2009 Mar;20(3):162-9. Epub 2009 Feb 10.PMID: 19205800 [PubMed - indexed for MEDLINE]Related articles

Risk conferred by HLA-DR and DQ for type 1 diabetes in 0-35-year age group in Sweden.

Sanjeevi CB, Sedimbi SK, Landin-Olsson M, Kockum I, Lernmark A; Swedish Childhood Diabetes and the Diabetes Incidence in Sweden Study Groups.

Ann N Y Acad Sci. 2008 Dec;1150:106-11.PMID: 19120278 [PubMed - indexed for MEDLINE]Related articles

GAD65 autoimmunity-clinical studies.

Uibo R, Lernmark A.

Adv Immunol. 2008;100:39-78. Review.PMID: 19111163 [PubMed - indexed for MEDLINE]Related articles

The non-inherited maternal HLA haplotype affects the risk for type 1 diabetes.

Akesson K, Carlsson A, Ivarsson SA, Johansson C, Weidby BM, Ludvigsson J, Gustavsson B, Lernmark A, Kockum I.

Int J Immunogenet. 2009 Feb;36(1):1-8. Epub 2008 Nov 25.PMID: 19055605 [PubMed - indexed for MEDLINE]Related articles

A comparison of serum and EDTA plasma in the measurement of glutamic acid decarboxylase autoantibodies (GADA) and autoantibodies to islet antigen-2 (IA-2A) using the RSR radioimmunoassay (RIA) and enzyme linked immunosorbent assay (ELISA) kits.

Rahmati K, Lernmark A, Becker C, Foltyn-Zadura A, Larsson K, Ivarsson SA, Törn C.

Clin Lab. 2008;54(7-8):227-35.PMID: 18942490 [PubMed - indexed for MEDLINE]Related articles

Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5.

Schulteis RD, Chu H, Dai X, Chen Y, Edwards B, Haribhai D, Williams CB, Malarkannan S, Hessner MJ, Glisic-Milosavljevic S, Jana S, Kerschen EJ, Ghosh S, Wang D, Kwitek AE, Lernmark A, Gorski J, Weiler H.

Blood. 2008 Dec 15;112(13):4905-14. Epub 2008 Sep 16.PMID: 18796632 [PubMed - indexed for MEDLINE]Related articles

Annual screening detects celiac disease in children with type 1 diabetes.

Larsson K, Carlsson A, Cederwall E, Jönsson B, Neiderud J, Jonsson B, Lernmark A, Ivarsson SA; Skåne Study Group.

Pediatr Diabetes. 2008 Aug;9(4 Pt 2):354-9.PMID: 18774995 [PubMed - indexed for MEDLINE]Related articles

Temporal trends of HLA genotype frequencies of type 1 diabetes patients in Sweden from 1986 to 2005 suggest altered risk.

Resic-Lindehammer S, Larsson K, Ortqvist E, Carlsson A, Cederwall E, Cilio CM, Ivarsson SA, Jönsson BA, Larsson HE, Lynch K, Neiderud J, Nilsson A, Sjöblad S, Lernmark A; Swedish Childhood Diabetes Study Group, Aili M, Bååth LE, Carlsson E, Edenwall H, Forsander G, Granstro BW, Gustavsson I, Hanås R, Hellenberg L, Hellgren H, Holmberg E, Hörnell H, Ivarsson SA, Johansson C, Jonsell G, Kockum K, Lindblad B, Lindh A, Ludvigsson J, Myrdal U, Neiderud J, Segnestam K, Sjöblad S, Skogsberg L, Strömberg L, Ståhle U, Thalme B, Tullus K, Tuvemo T, Wallensteen M, Westphal O, Aman J.

Acta Diabetol. 2008 Dec;45(4):231-5. Epub 2008 Sep 4.PMID: 18769865 [PubMed - indexed for MEDLINE]Related articles

Maternal enterovirus infection during pregnancy as a risk factor in offspring diagnosed with type 1 diabetes between 15 and 30 years of age.

Elfving M, Svensson J, Oikarinen S, Jonsson B, Olofsson P, Sundkvist G, Lindberg B, Lernmark A, Hyöty H, Ivarsson SA.

Exp Diabetes Res. 2008;2008:271958.PMID: 18670622 [PubMed - indexed for MEDLINE]Related articlesFree article

Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes.

Larsson HE, Hansson G, Carlsson A, Cederwall E, Jonsson B, Jönsson B, Larsson K, Lynch K, Neiderud J, Lernmark A, Ivarsson SA; DiPiS Study Group.

Diabetologia. 2008 Sep;51(9):1623-30. Epub 2008 Jul 1.PMID: 18592208 [PubMed - indexed for MEDLINE]Related articles

A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2.

Burbelo PD, Hirai H, Leahy H, Lernmark A, Ivarsson SA, Iadarola MJ, Notkins AL.

Diabetes Care. 2008 Sep;31(9):1824-6. Epub 2008 Jun 5.PMID: 18535195 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased lipid oxidation heralds diabetes onset in DR.lyp/lyp rats.

Akesson L, Gelling RW, Jensen R, Ogimoto K, Fuller JM, Pefley R, Manavi S, Lernmark A, Schwartz MW.

Exp Clin Endocrinol Diabetes. 2008 Aug;116(8):475-80. Epub 2008 May 9.PMID: 18465680 [PubMed - indexed for MEDLINE]Related articles

Comment on: Edghill et al. (2008) Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood: Diabetes 57:1034-1042, 2008.

Ivarsson SA, Lernmark A.

Diabetes. 2008 May;57(5):e9. No abstract available. PMID: 18443369 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of diabetic rats with encapsulated islets.

Sweet IR, Yanay O, Waldron L, Gilbert M, Fuller JM, Tupling T, Lernmark A, Osborne WR.

J Cell Mol Med. 2008 Dec;12(6B):2644-50. Epub 2008 Mar 28.PMID: 18373735 [PubMed - indexed for MEDLINE]Related articles

Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens.

Hirai H, Miura J, Hu Y, Larsson H, Larsson K, Lernmark A, Ivarsson SA, Wu T, Kingman A, Tzioufas AG, Notkins AL.

Clin Immunol. 2008 Jun;127(3):366-74. Epub 2008 Mar 24.PMID: 18359275 [PubMed - indexed for MEDLINE]Related articles

Cutaneous microvascular dysfunction is associated with human leukocyte antigen-DQ in youths with type 1 diabetes.

Odermarsky M, Lernmark A, Truedsson L, Liuba P.

Pediatr Res. 2008 Apr;63(4):420-2.PMID: 18356750 [PubMed - indexed for MEDLINE]Related articles

Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein.

Steed J, Gilliam LK, Harris RA, Lernmark A, Hampe CS.

J Immunol Methods. 2008 May 20;334(1-2):114-21. Epub 2008 Mar 7.PMID: 18353353 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA class II alleles specify phenotypes of ketosis-prone diabetes.

Nalini R, Gaur LK, Maldonado M, Hampe CS, Rodriguez L, Garza G, Lernmark A, Balasubramanyam A.

Diabetes Care. 2008 Jun;31(6):1195-200. Epub 2008 Mar 3.PMID: 18316396 [PubMed - indexed for MEDLINE]Related articlesFree article

Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype.

Lynch KF, Lernmark B, Merlo J, Cilio CM, Ivarsson SA, Lernmark A; Diabetes Prediction in Skåne (DiPiS) Study Group.

J Perinatol. 2008 Mar;28(3):211-7. Epub 2008 Feb 14.PMID: 18273032 [PubMed - indexed for MEDLINE]Related articles

Number of islet autoantibodies present in newly diagnosed type 1 diabetes children born to non-diabetic mothers is affected by islet autoantibodies present at birth.

Elfving M, Lindberg B, Lynch K, Månsson M, Sundkvist G, Lernmark A, Ivarsson SA.

Pediatr Diabetes. 2008 Apr;9(2):127-34. Epub 2008 Jan 19.PMID: 18221435 [PubMed - indexed for MEDLINE]Related articles

No evidence of association of the PDCD1 gene with Type 1 diabetes.

Asad S, Nikamo P, Törn C, Landin-Olsson M, Lernmark A, Alarcón-Riquelme M, Kockum I; Diabetes Incidence in Sweden Study Group.

Diabet Med. 2007 Dec;24(12):1473-7. Erratum in: Diabet Med. 2008 Feb;25(2):243. Fawwaz, S [corrected to Asad, S]. PMID: 18042085 [PubMed - indexed for MEDLINE]Related articles

Epitope analysis of GAD65 binding in both cord blood and at the time of clinical diagnosis of childhood type 1 diabetes.

Elfving M, Lindberg B, Lynch K, Ivarsson SA, Lernmark A, Hampe CS.

Horm Metab Res. 2007 Nov;39(11):790-6. Erratum in: Horm Metab Res. 2007 Dec;39(12):922. PMID: 17992632 [PubMed - indexed for MEDLINE]Related articles

Type 1 diabetes risk analysis on dried blood spot samples from population-based newborns: design and feasibility of an unselected case-control study.

Eising S, Svensson J, Skogstrand K, Nilsson A, Lynch K, Andersen PS, Lernmark A, Hougaard DM, Pociot F, Nørgaard-Pedersen B, Nerup J.

Paediatr Perinat Epidemiol. 2007 Nov;21(6):507-17.PMID: 17937736 [PubMed - indexed for MEDLINE]Related articles

Atherogenic vascular and lipid phenotypes in young patients with Type 1 diabetes are associated with diabetes high-risk HLA genotype.

Odermarsky M, Nilsson A, Lernmark A, Sjöblad S, Liuba P.

Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H3175-9. Epub 2007 Sep 28.PMID: 17906106 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet cell autoantibody levels after the diagnosis of young adult diabetic patients.

Jensen R, Gilliam L, Torn C, Landin-Olsson M, Palmer J, Akesson K, Kockum I, Lernmark B, Karlsson AF, Lynch KF, Breslow N, Lernmark A, Sundkvist G; Diabetes Incidence Study in Sweden group.

Diabet Med. 2007 Nov;24(11):1221-8. Epub 2007 Aug 24.PMID: 17725633 [PubMed - indexed for MEDLINE]Related articles

Decreased core temperature and increased beta(3)-adrenergic sensitivity in diabetes-prone BB rats.

Akesson L, Hawkins T, Jensen R, Fuller JM, Breslow NE, Lernmark A.

Diabetes Technol Ther. 2007 Aug;9(4):354-62.PMID: 17705691 [PubMed - indexed for MEDLINE]Related articles

The importance of CTLA-4 polymorphism and human leukocyte antigen genotype for the induction of diabetes-associated cytokine response in healthy school children.

Jonson CO, Lernmark A, Ludvigsson J, Rutledge EA, Hinkkanen A, Faresjö M.

Pediatr Diabetes. 2007 Aug;8(4):185-92.PMID: 17659059 [PubMed - indexed for MEDLINE]Related articles

IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5.

Shin JH, Janer M, McNeney B, Blay S, Deutsch K, Sanjeevi CB, Kockum I, Lernmark A, Graham J; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group, Arnqvist H, Björck E, Eriksson J, Nyström L, Ohlson LO, Scherstén B, Ostman J, Aili M, Bååth LE, Carlsson E, Edenwall H, Forsander G, Granström BW, Gustavsson I, Hanås R, Hellenberg L, Hellgren H, Holmberg E, Hörnell H, Ivarsson SA, Johansson C, Jonsell G, Kockum K, Lindblad B, Lindh A, Ludvigsson J, Myrdal U, Neiderud J, Segnestam K, Sjöblad S, Skogsberg L, Strömberg L, Ståhle U, Thalme B, Tullus K, Tuvemo T, Wallensteen M, Westphal O, Aman J.

Genes Immun. 2007 Sep;8(6):503-12. Epub 2007 Jul 19.PMID: 17641683 [PubMed - indexed for MEDLINE]Related articles

Multiple factors affect the loss of measurable C-peptide over 6 years in newly diagnosed 15- to 35-year-old diabetic subjects.

Jensen RA, Gilliam LK, Törn C, Landin-Olsson M, Karlsson FA, Palmer JP, Kockum I, Akesson K, Lernmark B, Lynch K, Breslow N, Lernmark A; Diabetes Incidence Study in Sweden (DISS) group.

J Diabetes Complications. 2007 Jul-Aug;21(4):205-13.PMID: 17616349 [PubMed - indexed for MEDLINE]Related articles

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis.

Thomson G, Valdes AM, Noble JA, Kockum I, Grote MN, Najman J, Erlich HA, Cucca F, Pugliese A, Steenkiste A, Dorman JS, Caillat-Zucman S, Hermann R, Ilonen J, Lambert AP, Bingley PJ, Gillespie KM, Lernmark A, Sanjeevi CB, Rønningen KS, Undlien DE, Thorsby E, Petrone A, Buzzetti R, Koeleman BP, Roep BO, Saruhan-Direskeneli G, Uyar FA, Günoz H, Gorodezky C, Alaez C, Boehm BO, Mlynarski W, Ikegami H, Berrino M, Fasano ME, Dametto E, Israel S, Brautbar C, Santiago-Cortes A, Frazer de Llado T, She JX, Bugawan TL, Rotter JI, Raffel L, Zeidler A, Leyva-Cobian F, Hawkins BR, Chan SH, Castano L, Pociot F, Nerup J.

Tissue Antigens. 2007 Aug;70(2):110-27.PMID: 17610416 [PubMed - indexed for MEDLINE]Related articles

Low-density cells isolated from the rat thymus resemble branched cortical macrophages and have a reduced capability of rescuing double-positive thymocytes from apoptosis in the BB-DP rat.

Sommandas V, Rutledge EA, Van Yserloo B, Fuller J, Lernmark A, Drexhage HA.

J Leukoc Biol. 2007 Oct;82(4):869-76. Epub 2007 Jun 28.PMID: 17599904 [PubMed - indexed for MEDLINE]Related articlesFree article

SUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients.

Sedimbi SK, Luo XR, Sanjeevi CB; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group, Lernmark A, Landin-Olsson M, Arnqvist H, Björck E, Nyström L, Ohlson LO, Scherstén B, Ostman J, Aili M, Bååth LE, Carlsson E, Edenwall H, Forsander G, Granström BW, Gustavsson I, Hanås R, Hellenberg L, Hellgren H, Holmberg E, Hörnell H, Ivarsson SA, Johansson C, Jonsell G, Kockum K, Lindblad B, Lindh A, Ludvigsson J, Myrdal U, Neiderud J, Segnestam K, Sjöblad S, Skogsberg L, Strömberg L, Ståhle U, Thalme B, Tullus K, Tuvemo T, Wallensteen M, Westphal O, Dahlquist G, Aman J.

Genes Immun. 2007 Sep;8(6):518-21. Epub 2007 Jun 7.PMID: 17554341 [PubMed - indexed for MEDLINE]Related articles

Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels.

Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A.

Exp Clin Endocrinol Diabetes. 2007 Apr;115(4):221-8.PMID: 17479437 [PubMed - indexed for MEDLINE]Related articles

Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations.

Laine AP, Holmberg H, Nilsson A, Ortqvist E, Kiviniemi M, Vaarala O, Akerblom HK, Simell O, Knip M, Ludvigsson J, Ivarsson SA, Larsson K, Lernmark A, Ilonen J; Finnish Paediatric Diabetes Registry.

Dis Markers. 2007;23(3):139-45.PMID: 17473382 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between increased relative birthweight and infections during pregnancy in children with a high-risk diabetes HLA genotype.

Larsson HE, Lynch K, Lernmark B, Hansson G, Lernmark A, Ivarsson SA.

Diabetologia. 2007 Jun;50(6):1161-9. Epub 2007 Apr 4.PMID: 17406854 [PubMed - indexed for MEDLINE]Related articles

The BioBreeding rat diabetes model is infected with Ljungan virus.

Niklasson B, Hultman T, Kallies R, Niedrig M, Nilsson R, Berggren PO, Juntti-Berggren L, Efendic S, Lernmark A, Klitz W.

Diabetologia. 2007 Jul;50(7):1559-60. Epub 2007 Apr 4. No abstract available. Erratum in: Diabetologia. 2007 Oct;50(10):2227. PMID: 17406852 [PubMed - indexed for MEDLINE]Related articles

GAD65 autoantibody epitopes in adult patients with latent autoimmune diabetes following GAD65 vaccination.

Bekris LM, Jensen RA, Lagerquist E, Hall TR, Agardh CD, Cilio CM, Lethagen AL, Lernmark A, Robertson JA, Hampe CS.

Diabet Med. 2007 May;24(5):521-6. Epub 2007 Mar 15.PMID: 17367313 [PubMed - indexed for MEDLINE]Related articles

A variant in the transcription factor 7-like 2 (TCF7L2) gene is associated with an increased risk of gestational diabetes mellitus.

Shaat N, Lernmark A, Karlsson E, Ivarsson S, Parikh H, Berntorp K, Groop L.

Diabetologia. 2007 May;50(5):972-9. Epub 2007 Mar 7.PMID: 17342473 [PubMed - indexed for MEDLINE]Related articles

Antibodies to GAD65 and peripheral nerve function in the DCCT.

Hoeldtke RD, Hampe CS, Bekris LM, Hobbs G, Bryner KD, Lernmark A; DCCT Research Group.

J Neuroimmunol. 2007 Apr;185(1-2):182-9. Epub 2007 Feb 27.PMID: 17328966 [PubMed - indexed for MEDLINE]Related articles

Species and epitope specificity of two 65 kDa glutamate decarboxylase time-resolved fluorometric immunoassays.

Rui M, Hampe CS, Wang C, Ling Z, Gorus FK, Lernmark A, Pipeleers DG, De Pauw PE.

J Immunol Methods. 2007 Jan 30;319(1-2):133-43. Epub 2006 Dec 14.PMID: 17210161 [PubMed - indexed for MEDLINE]Related articles

Cord blood islet autoantibodies are related to stress in the mother during pregnancy.

Lernmark B, Lynch K, Lernmark A.

Ann N Y Acad Sci. 2006 Oct;1079:345-9.PMID: 17130577 [PubMed - indexed for MEDLINE]Related articles

TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial.

Hagopian WA, Lernmark A, Rewers MJ, Simell OG, She JX, Ziegler AG, Krischer JP, Akolkar B.

Ann N Y Acad Sci. 2006 Oct;1079:320-6.PMID: 17130573 [PubMed - indexed for MEDLINE]Related articles

MHC class I chain-related gene-A is associated with IA2 and IAA but not GAD in Swedish type 1 diabetes mellitus.

Gupta M, Graham J, McNeeny B, Zarghami M, Landin-Olsson M, Hagopian WA, Palmer J, Lernmark A, Sanjeevi CB.

Ann N Y Acad Sci. 2006 Oct;1079:229-39.PMID: 17130560 [PubMed - indexed for MEDLINE]Related articles

Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats.

Fuller JM, Kwitek AE, Hawkins TJ, Moralejo DH, Lu W, Tupling TD, Macmurray AJ, Borchardt G, Hasinoff M, Lernmark A.

Diabetes. 2006 Dec;55(12):3351-7. Erratum in: Diabetes. 2007 Feb;56(2):549. PMID: 17130479 [PubMed - indexed for MEDLINE]Related articlesFree article