PubMed

Polymorphisms Identified through Genome-Wide Association Studies and Their Associations with Type 2 Diabetes in Chinese, Malays, and Asian-Indians in Singapore.

Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES.

J Clin Endocrinol Metab. 2009 Nov 5. [Epub ahead of print]PMID: 19892838 [PubMed - as supplied by publisher]Related articles

Gene team tree: a hierarchical representation of gene teams for all gap lengths.

Zhang M, Leong HW.

J Comput Biol. 2009 Oct;16(10):1383-98.PMID: 19803736 [PubMed - in process]Related articles

Development of a diabetes registry to improve quality of care in the National Healthcare Group in Singapore.

Toh MP, Leong HS, Lim BK.

Ann Acad Med Singapore. 2009 Jun;38(6):546-6. Review.PMID: 19565107 [PubMed - indexed for MEDLINE]Related articlesFree article

Bendamustine (Treanda) For Chronic Lymphocytic Leukemia: A Brief Overview.

Leong H, Bonk ME.

P T. 2009 Feb;34(2):73-76. No abstract available. PMID: 19561839 [PubMed - as supplied by publisher]Related articlesFree article

Nurse-administered propofol-alfentanil sedation using a patient-controlled analgesia pump compared with opioid-benzodiazepine sedation for outpatient colonoscopy.

Liu SY, Poon CM, Leung TL, Wong CW, Chan YL, Leung TC, Leong HT.

Endoscopy. 2009 Jun;41(6):522-8. Epub 2009 May 13.PMID: 19440955 [PubMed - indexed for MEDLINE]Related articles

Text-based over-representation analysis of microarray gene lists with annotation bias.

Leong HS, Kipling D.

Nucleic Acids Res. 2009 Jun;37(11):e79. Epub 2009 May 8.PMID: 19429895 [PubMed - indexed for MEDLINE]Related articlesFree article

Scan-directed unilateral neck exploration for primary hyperparathyroidism: eight-year results from a regional hospital.

Wong SW, Chan KW, Paulose NM, Leong HT.

Hong Kong Med J. 2009 Apr;15(2):118-21.PMID: 19342737 [PubMed - indexed for MEDLINE]Related articlesFree article

Outcomes and predictors of mortality and stoma formation in surgical management of colonoscopic perforations: a multicenter review.

Teoh AY, Poon CM, Lee JF, Leong HT, Ng SS, Sung JJ, Lau JY.

Arch Surg. 2009 Jan;144(1):9-13.PMID: 19153318 [PubMed - indexed for MEDLINE]Related articles

Feasibility study of day case thyroidectomy.

Teoh AY, Tang YC, Leong HT.

ANZ J Surg. 2008 Oct;78(10):864-6.PMID: 18959638 [PubMed - indexed for MEDLINE]Related articles

Reduced GFR and albuminuria in Chinese type 2 diabetes mellitus patients are both independently associated with activation of the TNF-alpha system.

Ng DP, Fukushima M, Tai BC, Koh D, Leong H, Imura H, Lim XL.

Diabetologia. 2008 Dec;51(12):2318-24. Epub 2008 Oct 7.PMID: 18839132 [PubMed - indexed for MEDLINE]Related articles

Green tea catechins inhibit angiogenesis through suppression of STAT3 activation.

Leong H, Mathur PS, Greene GL.

Breast Cancer Res Treat. 2009 Oct;117(3):505-15. Epub 2008 Sep 28.PMID: 18821062 [PubMed - in process]Related articles

Human herpesvirus 6 integrates within telomeric regions as evidenced by five different chromosomal sites.

Nacheva EP, Ward KN, Brazma D, Virgili A, Howard J, Leong HN, Clark DA.

J Med Virol. 2008 Nov;80(11):1952-8.PMID: 18814270 [PubMed - indexed for MEDLINE]Related articles

Unlabeled uses of intravenous immune globulin.

Leong H, Stachnik J, Bonk ME, Matuszewski KA.

Am J Health Syst Pharm. 2008 Oct 1;65(19):1815-24. Review.PMID: 18796422 [PubMed - indexed for MEDLINE]Related articles

Pre-emptive infiltration of Bupivacaine in laparoscopic total extraperitoneal hernioplasty: a randomized controlled trial.

Hon SF, Poon CM, Leong HT, Tang YC.

Hernia. 2009 Feb;13(1):53-6. Epub 2008 Aug 13.PMID: 18704618 [PubMed - indexed for MEDLINE]Related articles

Prevention and control of avian influenza in Singapore.

Leong HK, Goh CS, Chew ST, Lim CW, Lin YN, Chang SF, Yap HH, Chua SB.

Ann Acad Med Singapore. 2008 Jun;37(6):504-9. Review.PMID: 18618063 [PubMed - indexed for MEDLINE]Related articlesFree article

On preprocessing and antisymmetry in de novo peptide sequencing: improving efficiency and accuracy.

Ning K, Ye N, Leong HW.

J Bioinform Comput Biol. 2008 Jun;6(3):467-92.PMID: 18574859 [PubMed - indexed for MEDLINE]Related articles

Using indirect protein-protein interactions for protein complex prediction.

Chua HN, Ning K, Sung WK, Leong HW, Wong L.

J Bioinform Comput Biol. 2008 Jun;6(3):435-66.PMID: 18574858 [PubMed - indexed for MEDLINE]Related articles

An accurate and efficient algorithm for Peptide and ptm identification by tandem mass spectrometry.

Ning K, Ng HK, Leong HW.

Genome Inform. 2007;19:119-30.PMID: 18546510 [PubMed - indexed for MEDLINE]Related articlesFree article

A Merge-Decoupling Dead End Elimination algorithm for protein side-chain conformation.

Chong KF, Leong HW.

Int J Data Min Bioinform. 2007;1(4):372-88.PMID: 18402048 [PubMed - indexed for MEDLINE]Related articles

Recurrence pattern of fistula-in-ano in a Chinese population.

Poon CM, Ng DC, Ho-Yin MC, Li RS, Leong HT.

J Gastrointestin Liver Dis. 2008 Mar;17(1):53-7. Erratum in: J Gastrointestin Liver Dis. 2008 Sep;17(3):368. Chi-Ming, Poon [corrected to Poon, Chi-Ming]; Chung-Kei, Dennis Ng [corrected to Ng, Dennis Chung]; Ho-Yin, Michael Cheung [corrected to Cheung, Michael Ho]; Shiu-Ki, Raymond Li [corrected to Li, Raymond Shiu]; Heng-Tat, Leong [corrected to Leong, Heng-Tat]. PMID: 18392245 [PubMed - indexed for MEDLINE]Related articlesFree article

Smoking without exception adversely affects vascular structure and function in apparently healthy Chinese: implications in global atherosclerosis prevention.

Thomas GN, Chook P, Yip TW, Kwong SK, Chan TY, Qiao M, Huang XS, Guo DS, Feng JZ, Chan SW, Leong HC, Celermajer DS, Woo KS.

Int J Cardiol. 2008 Aug 18;128(2):172-7. Epub 2008 Jan 15.PMID: 18199502 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of high-flux-control genes of yeast through competition analyses in continuous cultures.

Delneri D, Hoyle DC, Gkargkas K, Cross EJ, Rash B, Zeef L, Leong HS, Davey HM, Hayes A, Kell DB, Griffith GW, Oliver SG.

Nat Genet. 2008 Jan;40(1):113-7. Epub 2007 Dec 23.PMID: 18157128 [PubMed - indexed for MEDLINE]Related articles

Vimentin autoantibodies induce platelet activation and formation of platelet-leukocyte conjugates via platelet-activating factor.

Leong HS, Mahesh BM, Day JR, Smith JD, McCormack AD, Ghimire G, Podor TJ, Rose ML.

J Leukoc Biol. 2008 Feb;83(2):263-71. Epub 2007 Nov 1.PMID: 17974709 [PubMed - indexed for MEDLINE]Related articlesFree article

Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.

Chandramouli S, Yu CY, Yusoff P, Lao DH, Leong HF, Mizuno K, Guy GR.

J Biol Chem. 2008 Jan 18;283(3):1679-91. Epub 2007 Nov 1.PMID: 17974561 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety of nurse-administered propofol sedation using PCA pump for outpatient colonoscopy in Chinese patients: a pilot study.

Poon CM, Leung TL, Wong CW, Chan YL, Leung TC, Leong HT.

Asian J Surg. 2007 Oct;30(4):239-43.PMID: 17962125 [PubMed - indexed for MEDLINE]Related articlesFree article

Using indirect protein-protein interactions for protein complex predication.

Chua HN, Ning K, Sung WK, Leong HW, Wong L.

Comput Syst Bioinformatics Conf. 2007;6:97-109.PMID: 17951816 [PubMed - indexed for MEDLINE]Related articlesFree article

Algorithm for peptide sequencing by tandem mass spectrometry based on better preprocessing and anti-symmetric computational model.

Ning K, Leong HW.

Comput Syst Bioinformatics Conf. 2007;6:19-30.PMID: 17951809 [PubMed - indexed for MEDLINE]Related articlesFree article

Secondary and tertiary hyperparathyroidism: role of preoperative localization.

Lai EC, Ching AS, Leong HT.

ANZ J Surg. 2007 Oct;77(10):880-2.PMID: 17803554 [PubMed - indexed for MEDLINE]Related articles

Role of prophylactic endoscopic sphincterotomy in patients with acute biliary pancreatitis due to transient common bile duct obstruction.

Teoh AY, Poon MC, Leong HT.

J Gastroenterol Hepatol. 2007 Sep;22(9):1415-8. Epub 2007 Jul 20.PMID: 17645462 [PubMed - indexed for MEDLINE]Related articles

Transmission of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation.

Kamble RT, Clark DA, Leong HN, Heslop HE, Brenner MK, Carrum G.

Bone Marrow Transplant. 2007 Sep;40(6):563-6. Epub 2007 Jul 16.PMID: 17637686 [PubMed - indexed for MEDLINE]Related articles

Kruppel-like factor 5 modulates p53-independent apoptosis through Pim1 survival kinase in cancer cells.

Zhao Y, Hamza MS, Leong HS, Lim CB, Pan YF, Cheung E, Soo KC, Iyer NG.

Oncogene. 2008 Jan 3;27(1):1-8. Epub 2007 Jul 2.PMID: 17603560 [PubMed - indexed for MEDLINE]Related articles

PepSOM: an algorithm for peptide identification by tandem mass spectrometry based on SOM.

Ning K, Ng HK, Leong HW.

Genome Inform. 2006;17(2):194-205.PMID: 17503392 [PubMed - indexed for MEDLINE]Related articles

The distribution and deposition algorithm for multiple oligo nucleotide arrays.

Ning K, Leong HW.

Genome Inform. 2006;17(2):89-99.PMID: 17503382 [PubMed - indexed for MEDLINE]Related articles

Inhibition of mammary tumorigenesis in the C3(1)/SV40 mouse model by green tea.

Leong H, Mathur PS, Greene GL.

Breast Cancer Res Treat. 2008 Feb;107(3):359-69. Epub 2007 May 5.PMID: 17484049 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies to vimentin cause accelerated rejection of cardiac allografts.

Mahesh B, Leong HS, McCormack A, Sarathchandra P, Holder A, Rose ML.

Am J Pathol. 2007 Apr;170(4):1415-27.PMID: 17392180 [PubMed - indexed for MEDLINE]Related articlesFree article

Predictive factors of long hospital stay after laparoscopic cholecystectomy.

Tsang YY, Poon CM, Lee KW, Leong HT.

Asian J Surg. 2007 Jan;30(1):23-8.PMID: 17337367 [PubMed - indexed for MEDLINE]Related articlesFree article

Fine-needle aspiration cytology of thyroid nodules--how well are we doing?

Cheung YS, Poon CM, Mak SM, Suen MW, Leong HT.

Hong Kong Med J. 2007 Feb;13(1):12-5.PMID: 17277386 [PubMed - indexed for MEDLINE]Related articlesFree article

Modeling and characterization of multi-charge mass spectra for peptide sequencing.

Chong KF, Ning K, Leong HW, Pevzner P.

J Bioinform Comput Biol. 2006 Dec;4(6):1329-52.PMID: 17245817 [PubMed - indexed for MEDLINE]Related articles

Survey on mammographic screening among women aged 40 to 65 years old at polyclinics.

Leong HS, Heng R, Emmanuel SC.

Singapore Med J. 2007 Jan;48(1):34-40.PMID: 17245514 [PubMed - indexed for MEDLINE]Related articlesFree article

Human herpesvirus 6 DNA levels in cerebrospinal fluid due to primary infection differ from those due to chromosomal viral integration and have implications for diagnosis of encephalitis.

Ward KN, Leong HN, Thiruchelvam AD, Atkinson CE, Clark DA.

J Clin Microbiol. 2007 Apr;45(4):1298-304. Epub 2007 Jan 17.PMID: 17229866 [PubMed - indexed for MEDLINE]Related articlesFree article

Towards a better solution to the shortest common supersequence problem: the deposition and reduction algorithm.

Ning K, Leong HW.

BMC Bioinformatics. 2006 Dec 12;7 Suppl 4:S12.PMID: 17217504 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise increases tissue-type plasminogen activator expression in rat cardiomyocytes.

Walinski HP, Gyorffy SF, Leong HS, Slaughter GR, Dawood F, Pate GE, Liu PP, Parker TG, Podor TJ.

Thromb Haemost. 2006 Dec;96(6):859-61. No abstract available. PMID: 17139388 [PubMed - indexed for MEDLINE]Related articles

The prevalence of chromosomally integrated human herpesvirus 6 genomes in the blood of UK blood donors.

Leong HN, Tuke PW, Tedder RS, Khanom AB, Eglin RP, Atkinson CE, Ward KN, Griffiths PD, Clark DA.

J Med Virol. 2007 Jan;79(1):45-51.PMID: 17133548 [PubMed - indexed for MEDLINE]Related articles

Enhanced in vivo homing of uncultured and selectively amplified cord blood CD34+ cells by cotransplantation with cord blood-derived unrestricted somatic stem cells.

Chan SL, Choi M, Wnendt S, Kraus M, Teng E, Leong HF, Merchav S.

Stem Cells. 2007 Feb;25(2):529-36. Epub 2006 Oct 26.PMID: 17068185 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical and epidemiological predictors of transmission in Severe Acute Respiratory Syndrome (SARS).

Chen MI, Chow AL, Earnest A, Leong HN, Leo YS.

BMC Infect Dis. 2006 Oct 18;6:151.PMID: 17049088 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term arginine deprivation results in large-scale modulation of hepatic gene expression in both normal and tumor cells: microarray bioinformatic analysis.

Leong HX, Simkevich C, Lesieur-Brooks A, Lau BW, Fugere C, Sabo E, Thompson NL.

Nutr Metab (Lond). 2006 Sep 8;3:37.PMID: 16961918 [PubMed]Related articlesFree article

A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation.

Lao DH, Chandramouli S, Yusoff P, Fong CW, Saw TY, Tai LP, Yu CY, Leong HF, Guy GR.

J Biol Chem. 2006 Oct 6;281(40):29993-30000. Epub 2006 Aug 7.PMID: 16893902 [PubMed - indexed for MEDLINE]Related articlesFree article

Understanding the super-spreading events of SARS in Singapore.

Chen MI, Loon SC, Leong HN, Leo YS.

Ann Acad Med Singapore. 2006 Jun;35(6):390-4.PMID: 16865188 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical and laboratory findings of SARS in Singapore.

Leong HN, Chan KP, Oon LL, Koay ES, Ng LC, Lee MA, Barkham T, Chen MI, Heng BH, Ling AE, Leo YS.

Ann Acad Med Singapore. 2006 May;35(5):332-9.PMID: 16830000 [PubMed - indexed for MEDLINE]Related articlesFree article

SARS in Singapore--predictors of disease severity.

Leong HN, Earnest A, Lim HH, Chin CF, Tan CS, Puhaindran ME, Tan AC, Chen MI, Leo YS.

Ann Acad Med Singapore. 2006 May;35(5):326-31.PMID: 16829999 [PubMed - indexed for MEDLINE]Related articlesFree article