PubMed

High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity.

Coviello AD, Sam S, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2009 Nov;94(11):4361-6. Epub 2009 Oct 16.PMID: 19837913 [PubMed - in process]Related articles

Peripubertal estrogen levels and physical activity affect femur geometry in young adult women.

Devlin MJ, Stetter CM, Lin HM, Beck TJ, Legro RS, Petit MA, Lieberman DE, Lloyd T.

Osteoporos Int. 2009 Jul 3. [Epub ahead of print]PMID: 19575140 [PubMed - as supplied by publisher]Related articles

Insulin resistance in women's health: why it matters and how to identify it.

Legro RS.

Curr Opin Obstet Gynecol. 2009 Aug;21(4):301-5. Review.PMID: 19550327 [PubMed - indexed for MEDLINE]Related articles

Body mass index and intercourse compliance.

Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC; for the National Institute of Child Health and Human Development-Reproductive Medicine Network.

Fertil Steril. 2009 Jun 19. [Epub ahead of print]PMID: 19540480 [PubMed - as supplied by publisher]Related articles

Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial.

Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC; for the National Institute of Child Health and Human Development–Reproductive Medicine Network.

Fertil Steril. 2009 Jun 19. [Epub ahead of print]PMID: 19540477 [PubMed - as supplied by publisher]Related articles

Predictors of pregnancy in women with polycystic ovary syndrome.

Rausch ME, Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER, Coutifaris C; Reproductive Medicine Network.

J Clin Endocrinol Metab. 2009 Sep;94(9):3458-66. Epub 2009 Jun 9.PMID: 19509098 [PubMed - indexed for MEDLINE]Related articles

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women.

Chen C, Wickenheisser J, Ewens KG, Ankener W, Legro RS, Dunaif A, McAllister JM, Spielman RS, Strauss JF 3rd.

Mol Hum Reprod. 2009 Aug;15(8):459-69. Epub 2009 May 29.PMID: 19482904 [PubMed - indexed for MEDLINE]Related articles

The role of genetic variation in the lamin a/c gene in the etiology of polycystic ovary syndrome.

Urbanek M, Nampiaparampil G, D'Souza J, Sefton E, Ackerman C, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2009 Jul;94(7):2665-9. Epub 2009 Apr 28.PMID: 19401371 [PubMed - indexed for MEDLINE]Related articles

Evidence for association between polycystic ovary syndrome (PCOS) and TCF7L2 and glucose intolerance in women with PCOS and TCF7L2.

Biyasheva A, Legro RS, Dunaif A, Urbanek M.

J Clin Endocrinol Metab. 2009 Jul;94(7):2617-25. Epub 2009 Apr 7.PMID: 19351735 [PubMed - indexed for MEDLINE]Related articles

Heirarchical clustering and beyond in PCOS endometrium: brave new world.

Legro RS, McAllister JM.

J Clin Endocrinol Metab. 2009 Apr;94(4):1084-5. No abstract available. PMID: 19349472 [PubMed - indexed for MEDLINE]Related articles

Epinephrine is associated with both erectile dysfunction and lower urinary tract symptoms.

Trussell JC, Kunselman AR, Legro RS.

Fertil Steril. 2008 Dec 3. [Epub ahead of print]PMID: 19062003 [PubMed - as supplied by publisher]Related articles

Impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women: do we need a new drug?

Legro RS.

J Clin Endocrinol Metab. 2008 Nov;93(11):4218-20. No abstract available. PMID: 18987279 [PubMed - indexed for MEDLINE]Related articlesFree article

The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report.

Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF; Task Force on the Phenotype of the Polycystic Ovary Syndrome of The Androgen Excess and PCOS Society.

Fertil Steril. 2009 Feb;91(2):456-88. Epub 2008 Oct 23. Review.PMID: 18950759 [PubMed - indexed for MEDLINE]Related articles

Individualizing infertility therapy with pharmacogenomics: vanity or vanguard?

Legro RS.

Pharmacogenomics. 2008 Sep;9(9):1179-81. No abstract available. PMID: 18781843 [PubMed - indexed for MEDLINE]Related articles

Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome.

Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice LC; Reproductive Medicine Network.

J Clin Endocrinol Metab. 2008 Aug;93(8):3124-7. Epub 2008 May 27.PMID: 18505764 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic phenotype in the brothers of women with polycystic ovary syndrome.

Sam S, Coviello AD, Sung YA, Legro RS, Dunaif A.

Diabetes Care. 2008 Jun;31(6):1237-41. Epub 2008 Mar 10.PMID: 18332151 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of hormonal and metabolic markers after a high-fat, Western meal versus a low-fat, high-fiber meal in women with polycystic ovary syndrome.

Katcher HI, Kunselman AR, Dmitrovic R, Demers LM, Gnatuk CL, Kris-Etherton PM, Legro RS.

Fertil Steril. 2009 Apr;91(4):1175-82. Epub 2008 Mar 10.PMID: 18331737 [PubMed - indexed for MEDLINE]Related articles

Diminished paternity and gonadal function with increasing obesity in men.

Pauli EM, Legro RS, Demers LM, Kunselman AR, Dodson WC, Lee PA.

Fertil Steril. 2008 Aug;90(2):346-51. Epub 2008 Feb 21.PMID: 18291378 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperandrogenism and hyperinsulinism in children of women with polycystic ovary syndrome: a controlled study.

Kent SC, Gnatuk CL, Kunselman AR, Demers LM, Lee PA, Legro RS.

J Clin Endocrinol Metab. 2008 May;93(5):1662-9. Epub 2008 Feb 12.PMID: 18270257 [PubMed - indexed for MEDLINE]Related articlesFree article

Does polycystic ovary syndrome increase the disparity in metabolic syndrome and cardiovascular-related health for African-American women?

Coney P, Ladson G, Sweet S, Legro RS.

Semin Reprod Med. 2008 Jan;26(1):35-8. Review.PMID: 18181080 [PubMed - indexed for MEDLINE]Related articles

New directions in polycystic ovary syndrome.

Legro RS.

Semin Reprod Med. 2008 Jan;26(1):3-4. No abstract available. PMID: 18181076 [PubMed - indexed for MEDLINE]Related articles

The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome.

Katcher HI, Legro RS, Kunselman AR, Gillies PJ, Demers LM, Bagshaw DM, Kris-Etherton PM.

Am J Clin Nutr. 2008 Jan;87(1):79-90.PMID: 18175740 [PubMed - indexed for MEDLINE]Related articlesFree article

Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial.

McGovern PG, Carson SA, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC; National Institute of Child Health and Human Development-Reproductive Medicine Network.

Fertil Steril. 2008 Oct;90(4):1283-6. Epub 2007 Dec 20.PMID: 18082737 [PubMed - indexed for MEDLINE]Related articlesFree article

A comparison of methods and results in recruiting white and black women into reproductive studies: the MMC-PSU cooperative center on reproduction experience.

Sweet S, Legro RS, Coney P.

Contemp Clin Trials. 2008 Jul;29(4):478-81. Epub 2007 Nov 22.PMID: 18082470 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndrome.

Sam S, Sung YA, Legro RS, Dunaif A.

Metabolism. 2008 Jan;57(1):84-9.PMID: 18078863 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of continuous versus cyclical oral contraception: a randomized controlled trial.

Legro RS, Pauli JG, Kunselman AR, Meadows JW, Kesner JS, Zaino RJ, Demers LM, Gnatuk CL, Dodson WC.

J Clin Endocrinol Metab. 2008 Feb;93(2):420-9. Epub 2007 Dec 4.PMID: 18056769 [PubMed - indexed for MEDLINE]Related articlesFree article

Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene.

Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Ewens KG, Spielman RS, Leppert PC, Myers ER; Reproductive Medicine Network.

J Clin Endocrinol Metab. 2008 Mar;93(3):792-800. Epub 2007 Nov 13.PMID: 18000088 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype.

Urbanek M, Sam S, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2007 Nov;92(11):4191-8. Epub 2007 Sep 4.PMID: 17785364 [PubMed - indexed for MEDLINE]Related articlesFree article

Polycystic ovary syndrome.

Norman RJ, Dewailly D, Legro RS, Hickey TE.

Lancet. 2007 Aug 25;370(9588):685-97. Review.PMID: 17720020 [PubMed - indexed for MEDLINE]Related articles

Hysterectomy and loss of fertility: implications for women's mental health.

Leppert PC, Legro RS, Kjerulff KH.

J Psychosom Res. 2007 Sep;63(3):269-74. Epub 2007 Aug 2.PMID: 17719364 [PubMed - indexed for MEDLINE]Related articles

Erectile dysfunction: does insulin resistance play a part?

Trussell JC, Legro RS.

Fertil Steril. 2007 Oct;88(4):771-8. Epub 2007 May 11. Review.PMID: 17498710 [PubMed - indexed for MEDLINE]Related articles

The effects of metformin and rosiglitazone, alone and in combination, on the ovary and endometrium in polycystic ovary syndrome.

Legro RS, Zaino RJ, Demers LM, Kunselman AR, Gnatuk CL, Williams NI, Dodson WC.

Am J Obstet Gynecol. 2007 Apr;196(4):402.e1-10; discussion 402.e10-1.PMID: 17403436 [PubMed - indexed for MEDLINE]Related articles

Pregnancy considerations in women with polycystic ovary syndrome.

Legro RS.

Clin Obstet Gynecol. 2007 Mar;50(1):295-304.PMID: 17304043 [PubMed - indexed for MEDLINE]Related articles

Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.

Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER; Cooperative Multicenter Reproductive Medicine Network.

N Engl J Med. 2007 Feb 8;356(6):551-66.PMID: 17287476 [PubMed - indexed for MEDLINE]Related articlesFree article

A 27-year-old woman with a diagnosis of polycystic ovary syndrome.

Legro RS.

JAMA. 2007 Feb 7;297(5):509-19.PMID: 17284701 [PubMed - indexed for MEDLINE]Related articles

The role of genes and environment in the etiology of PCOS.

Diamanti-Kandarakis E, Kandarakis H, Legro RS.

Endocrine. 2006 Aug;30(1):19-26. Review.PMID: 17185788 [PubMed - indexed for MEDLINE]Related articles

Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome.

McGovern PG, Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC; National Institutes for Child Health and Human Development-Reproductive Medicine Network.

Fertil Steril. 2007 Feb;87(2):442-4. Epub 2006 Dec 4.PMID: 17141768 [PubMed - indexed for MEDLINE]Related articlesFree article

The Pregnancy in Polycystic Ovary Syndrome study: baseline characteristics of the randomized cohort including racial effects.

Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, McGovern PG, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Guidice LC, Leppert PC; Reproductive Medicine Network.

Fertil Steril. 2006 Oct;86(4):914-33. Epub 2006 Sep 11.PMID: 16963034 [PubMed - indexed for MEDLINE]Related articles

Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline.

Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF; Androgen Excess Society.

J Clin Endocrinol Metab. 2006 Nov;91(11):4237-45. Epub 2006 Aug 29.PMID: 16940456 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term, low-dose flutamide does not cause hepatotoxicity in hyperandrogenic women.

Legro RS.

Nat Clin Pract Endocrinol Metab. 2006 Apr;2(4):188-9. No abstract available. PMID: 16932279 [PubMed - indexed for MEDLINE]Related articles

Fine mapping of genetic susceptibility to polycystic ovary syndrome on chromosome 19p13.2 and tests for regulatory activity.

Stewart DR, Dombroski BA, Urbanek M, Ankener W, Ewens KG, Wood JR, Legro RS, Strauss JF 3rd, Dunaif A, Spielman RS.

J Clin Endocrinol Metab. 2006 Oct;91(10):4112-7. Epub 2006 Jul 25.PMID: 16868051 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma interleukin 6 levels are elevated in polycystic ovary syndrome independently of obesity or sleep apnea.

Vgontzas AN, Trakada G, Bixler EO, Lin HM, Pejovic S, Zoumakis E, Chrousos GP, Legro RS.

Metabolism. 2006 Aug;55(8):1076-82.PMID: 16839844 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes and polycystic ovary syndrome.

Legro RS.

Fertil Steril. 2006 Jul;86 Suppl 1:S16-7.PMID: 16798276 [PubMed - indexed for MEDLINE]Related articles

Association of obesity with treatment outcomes in ovulatory infertile women undergoing superovulation and intrauterine insemination.

Dodson WC, Kunselman AR, Legro RS.

Fertil Steril. 2006 Sep;86(3):642-6. Epub 2006 Jun 16.PMID: 16782095 [PubMed - indexed for MEDLINE]Related articles

Obesity and the role of gut and adipose hormones in female reproduction.

Gosman GG, Katcher HI, Legro RS.

Hum Reprod Update. 2006 Sep-Oct;12(5):585-601. Epub 2006 Jun 14. Review.PMID: 16775192 [PubMed - indexed for MEDLINE]Related articlesFree article

A twenty-first century research agenda for polycystic ovary syndrome.

Legro RS, Azziz R, Giudice L.

Best Pract Res Clin Endocrinol Metab. 2006 Jun;20(2):331-6.PMID: 16772161 [PubMed - indexed for MEDLINE]Related articles

Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome.

Hickey TE, Legro RS, Norman RJ.

J Clin Endocrinol Metab. 2006 Jul;91(7):2789-91. Epub 2006 Apr 24.PMID: 16636126 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndrome.

Sam S, Legro RS, Essah PA, Apridonidze T, Dunaif A.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):7030-5. Epub 2006 Apr 21.PMID: 16632599 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome.

Ehrmann DA, Liljenquist DR, Kasza K, Azziz R, Legro RS, Ghazzi MN; PCOS/Troglitazone Study Group.

J Clin Endocrinol Metab. 2006 Jan;91(1):48-53. Epub 2005 Oct 25.PMID: 16249284 [PubMed - indexed for MEDLINE]Related articlesFree article

Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance.

Coviello AD, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2006 Feb;91(2):492-7. Epub 2005 Oct 25.PMID: 16249280 [PubMed - indexed for MEDLINE]Related articlesFree article