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    Results: 24

    1.

    ChREBP is a Negative Regulator of ARNT/HIF-1{beta} Gene Expression in Pancreatic Islet {beta}-Cells.

    Noordeen NA, Khera TK, Sun G, Longbottom ER, Pullen TJ, da Silva Xavier G, Rutter GA, Leclerc I.

    Diabetes. 2009 Oct 15. [Epub ahead of print]PMID: 19833882 [PubMed - as supplied by publisher]Related articles

    2.

    The AMP-regulated kinase family: enigmatic targets for diabetes therapy.

    Rutter GA, Leclerc I.

    Mol Cell Endocrinol. 2009 Jan 15;297(1-2):41-9. Epub 2008 Jun 19. Review.PMID: 18611432 [PubMed - indexed for MEDLINE]Related articles

    3.

    The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia.

    Jacquet S, Zarrinpashneh E, Chavey A, Ginion A, Leclerc I, Viollet B, Rutter GA, Bertrand L, Marber MS.

    Cardiovasc Res. 2007 Dec 1;76(3):465-72. Epub 2007 Aug 8.PMID: 17765884 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver.

    Rencurel F, Foretz M, Kaufmann MR, Stroka D, Looser R, Leclerc I, da Silva Xavier G, Rutter GA, Viollet B, Meyer UA.

    Mol Pharmacol. 2006 Dec;70(6):1925-34. Epub 2006 Sep 20.PMID: 16988011 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic beta-cells.

    da Silva Xavier G, Rutter GA, Diraison F, Andreolas C, Leclerc I.

    J Lipid Res. 2006 Nov;47(11):2482-91. Epub 2006 Aug 4.PMID: 16891625 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Over-expression of AMP-activated protein kinase impairs pancreatic {beta}-cell function in vivo.

    Richards SK, Parton LE, Leclerc I, Rutter GA, Smith RM.

    J Endocrinol. 2005 Nov;187(2):225-35.PMID: 16293770 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Impact of adenoviral transduction with SREBP1c or AMPK on pancreatic islet gene expression profile: analysis with oligonucleotide microarrays.

    Diraison F, Motakis E, Parton LE, Nason GP, Leclerc I, Rutter GA.

    Diabetes. 2004 Dec;53 Suppl 3:S84-91.PMID: 15561928 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    AMP-activated protein kinase: a new beta-cell glucose sensor?: Regulation by amino acids and calcium ions.

    Leclerc I, Rutter GA.

    Diabetes. 2004 Dec;53 Suppl 3:S67-74.PMID: 15561925 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Imaging glucose-regulated insulin secretion and gene expression in single islet beta-cells: control by AMP-activated protein kinase.

    Rutter GA, Leclerc I, Tsuboi T, Xavier Gda S, Diraison F, Qian Q.

    Cell Biochem Biophys. 2004;40(3 Suppl):179-90. Review.PMID: 15289653 [PubMed - indexed for MEDLINE]Related articles

    10.

    Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM.

    Ma D, Shield JP, Dean W, Leclerc I, Knauf C, Burcelin R R, Rutter GA, Kelsey G.

    J Clin Invest. 2004 Aug;114(3):339-48.PMID: 15286800 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.

    Leclerc I, Woltersdorf WW, da Silva Xavier G, Rowe RL, Cross SE, Korbutt GS, Rajotte RV, Smith R, Rutter GA.

    Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E1023-31. Epub 2004 Feb 10.PMID: 14871885 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

    Diraison F, Parton L, Ferré P, Foufelle F, Briscoe CP, Leclerc I, Rutter GA.

    Biochem J. 2004 Mar 15;378(Pt 3):769-78.PMID: 14690455 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics.

    Tsuboi T, da Silva Xavier G, Leclerc I, Rutter GA.

    J Biol Chem. 2003 Dec 26;278(52):52042-51. Epub 2003 Oct 7.PMID: 14532293 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.

    Rutter GA, Da Silva Xavier G, Leclerc I.

    Biochem J. 2003 Oct 1;375(Pt 1):1-16. Review.PMID: 12839490 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression.

    da Silva Xavier G, Leclerc I, Varadi A, Tsuboi T, Moule SK, Rutter GA.

    Biochem J. 2003 May 1;371(Pt 3):761-74.PMID: 12589707 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Expression of COUP-TFII in metabolic tissues during development.

    Zhang P, Bennoun M, Gogard C, Bossard P, Leclerc I, Kahn A, Vasseur-Cognet M.

    Mech Dev. 2002 Nov;119(1):109-14.PMID: 12385758 [PubMed - indexed for MEDLINE]Related articles

    17.

    AMP- and stress-activated protein kinases: key regulators of glucose-dependent gene transcription in mammalian cells?

    Leclerc I, da Silva Xavier G, Rutter GA.

    Prog Nucleic Acid Res Mol Biol. 2002;71:69-90. Review.PMID: 12102561 [PubMed - indexed for MEDLINE]Related articles

    18.

    Role of AMP-activated protein kinase in the regulation of gene transcription.

    Leclerc I, Viollet B, da Silva Xavier G, Kahn A, Rutter GA.

    Biochem Soc Trans. 2002 Apr;30(2):307-11. Review.PMID: 12023870 [PubMed - indexed for MEDLINE]Related articles

    19.

    Loss of brain volume in endogenous Cushing's syndrome and its reversibility after correction of hypercortisolism.

    Bourdeau I, Bard C, Noël B, Leclerc I, Cordeau MP, Bélair M, Lesage J, Lafontaine L, Lacroix A.

    J Clin Endocrinol Metab. 2002 May;87(5):1949-54.PMID: 11994323 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Hepatocyte nuclear factor-4alpha involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase.

    Leclerc I, Lenzner C, Gourdon L, Vaulont S, Kahn A, Viollet B.

    Diabetes. 2001 Jul;50(7):1515-21.PMID: 11423471 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression.

    da Silva Xavier G, Leclerc I, Salt IP, Doiron B, Hardie DG, Kahn A, Rutter GA.

    Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4023-8.PMID: 10760274 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Present and potential future use of gene therapy for the treatment of non-insulin dependent diabetes mellitus (Review).

    Freeman DJ, Leclerc I, Rutter GA.

    Int J Mol Med. 1999 Dec;4(6):585-92. Review.PMID: 10567666 [PubMed - indexed for MEDLINE]Related articles

    23.

    The 5'-AMP-activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex.

    Leclerc I, Kahn A, Doiron B.

    FEBS Lett. 1998 Jul 17;431(2):180-4.PMID: 9708898 [PubMed - indexed for MEDLINE]Related articles

    24.

    No change in glucose tolerance and substrate oxidation after a high-carbohydrate, low-fat diet.

    Leclerc I, Davignon I, Lopez D, Garrel DR.

    Metabolism. 1993 Mar;42(3):365-70.PMID: 8487656 [PubMed - indexed for MEDLINE]Related articles

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