PubMed

Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells.

Lee MY, Garvey SM, Baras AS, Lemmon JA, Gomez MF, Schoppee Bortz PD, Daum G, Leboeuf RC, Wamhoff BR.

Hum Mol Genet. 2009 Nov 19. [Epub ahead of print]PMID: 19926569 [PubMed - as supplied by publisher]Related articles

Tumor necrosis factor-alpha and lymphotoxin-alpha increase macrophage ABCA1 by gene expression and protein stabilization via different receptors.

Edgel KA, Leboeuf RC, Oram JF.

Atherosclerosis. 2009 Oct 22. [Epub ahead of print]PMID: 19913791 [PubMed - as supplied by publisher]Related articles

beta-Cell-specific overexpression of glutathione peroxidase preserves intranuclear MafA and reverses diabetes in db/db mice.

Harmon JS, Bogdani M, Parazzoli SD, Mak SS, Oseid EA, Berghmans M, Leboeuf RC, Robertson RP.

Endocrinology. 2009 Nov;150(11):4855-62. Epub 2009 Oct 9.PMID: 19819955 [PubMed - indexed for MEDLINE]Related articles

A novel signaling pathway: fibroblast nicotinic receptor alpha1 binds urokinase and promotes renal fibrosis.

Zhang G, Kernan KA, Thomas A, Collins S, Song Y, Li L, Zhu W, Leboeuf RC, Eddy AA.

J Biol Chem. 2009 Oct 16;284(42):29050-64. Epub 2009 Aug 18.PMID: 19690163 [PubMed - in process]Related articles

Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse.

Hsing LC, Kirk EA, McMillen TS, Hsiao SH, Caldwell M, Houston B, Rudensky AY, Leboeuf RC.

J Autoimmun. 2009 Aug 5. [Epub ahead of print]PMID: 19664906 [PubMed - as supplied by publisher]Related articles

Receptors for tumor necrosis factor-alpha play a protective role against obesity and alter adipose tissue macrophage status.

Pamir N, McMillen TS, Kaiyala KJ, Schwartz MW, LeBoeuf RC.

Endocrinology. 2009 Sep;150(9):4124-34. Epub 2009 May 28.PMID: 19477937 [PubMed - indexed for MEDLINE]Related articles

Overexpression of apolipoprotein A5 in mice is not protective against body weight gain and aberrant glucose homeostasis.

Pamir N, McMillen TS, Li YI, Lai CM, Wong H, LeBoeuf RC.

Metabolism. 2009 Apr;58(4):560-7.PMID: 19303979 [PubMed - indexed for MEDLINE]Related articles

Diabetes-accelerated atherosclerosis and inflammation.

Kanter JE, Averill MM, Leboeuf RC, Bornfeldt KE.

Circ Res. 2008 Oct 10;103(8):e116-7. No abstract available. PMID: 18845812 [PubMed - indexed for MEDLINE]Related articlesFree article

Tanshinone IIA reduces macrophage death induced by hydrogen peroxide by upregulating glutathione peroxidase.

Li YI, Elmer G, Leboeuf RC.

Life Sci. 2008 Oct 10;83(15-16):557-62. Epub 2008 Aug 16.PMID: 18762198 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.

Zhang WJ, Bird KE, McMillen TS, LeBoeuf RC, Hagen TM, Frei B.

Circulation. 2008 Jan 22;117(3):421-8. Epub 2007 Dec 24.PMID: 18158360 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of diabetes in NOD mice by GAD65-specific monoclonal antibodies is epitope specific and accompanied by anti-idiotypic antibodies.

Hall TR, Bogdani M, Leboeuf RC, Kirk EA, Maziarz M, Banga JP, Oak S, Pennington CA, Hampe CS.

Immunology. 2008 Apr;123(4):547-54. Epub 2007 Nov 14.PMID: 18005036 [PubMed - indexed for MEDLINE]Related articlesFree article

Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research.

Katz R, Hamilton JA, Pownall HJ, Deckelbaum RJ, Hillard CJ, Leboeuf RC, Watkins PA.

J Mol Neurosci. 2007 Sep;33(1):146-50.PMID: 17901559 [PubMed - indexed for MEDLINE]Related articles

Mapping genes responsible for strain-specific iron phenotypes in murine chromosome substitution strains.

Ajioka RS, LeBoeuf RC, Gillespie RR, Amon LM, Kushner JP.

Blood Cells Mol Dis. 2007 Sep-Oct;39(2):199-205. Epub 2007 May 9.PMID: 17493847 [PubMed - indexed for MEDLINE]Related articlesFree article

Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques?

Kanter JE, Johansson F, LeBoeuf RC, Bornfeldt KE.

Circ Res. 2007 Mar 30;100(6):769-81. Review.PMID: 17395883 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of human myeloperoxidase by macrophages promotes atherosclerosis in mice.

McMillen TS, Heinecke JW, LeBoeuf RC.

Circulation. 2005 May 31;111(21):2798-804. Epub 2005 May 23.PMID: 15911707 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK.

Ladiges WC, Knoblaugh SE, Morton JF, Korth MJ, Sopher BL, Baskin CR, MacAuley A, Goodman AG, LeBoeuf RC, Katze MG.

Diabetes. 2005 Apr;54(4):1074-81.PMID: 15793246 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum amyloid A and lipoprotein retention in murine models of atherosclerosis.

O'Brien KD, McDonald TO, Kunjathoor V, Eng K, Knopp EA, Lewis K, Lopez R, Kirk EA, Chait A, Wight TN, deBeer FC, LeBoeuf RC.

Arterioscler Thromb Vasc Biol. 2005 Apr;25(4):785-90. Epub 2005 Feb 3.PMID: 15692094 [PubMed - indexed for MEDLINE]Related articlesFree article

Norgestimate and medroxyprogesterone acetate do not attenuate the atheroprotective effects of 17beta-estradiol in ovariectomized, apolipoprotein E-deficient mice.

Shultz JM, Zhu XD, Knopp RH, Leboeuf RC, Rosenfeld ME.

Fertil Steril. 2004 Oct;82 Suppl 3:1133-9.PMID: 15474086 [PubMed - indexed for MEDLINE]Related articles

Hyperlipidemia aggravates renal disease in B6.ROP Os/+ mice.

Mühlfeld AS, Spencer MW, Hudkins KL, Kirk E, LeBoeuf RC, Alpers CE.

Kidney Int. 2004 Oct;66(4):1393-402.PMID: 15458432 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia and hyperlipidemia act synergistically to induce renal disease in LDL receptor-deficient BALB mice.

Spencer MW, Mühlfeld AS, Segerer S, Hudkins KL, Kirk E, LeBoeuf RC, Alpers CE.

Am J Nephrol. 2004 Jan-Feb;24(1):20-31. Epub 2003 Dec 10.PMID: 14671436 [PubMed - indexed for MEDLINE]Related articles

Mice deficient in apolipoprotein E but not LDL receptors are resistant to accelerated atherosclerosis associated with obesity.

Schreyer SA, Lystig TC, Vick CM, LeBoeuf RC.

Atherosclerosis. 2003 Nov;171(1):49-55.PMID: 14642405 [PubMed - indexed for MEDLINE]Related articles

The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.

Vidal J, Verchere CB, Andrikopoulos S, Wang F, Hull RL, Cnop M, Olin KL, LeBoeuf RC, O'Brien KD, Chait A, Kahn SE.

Diabetologia. 2003 Jan;46(1):71-9. Epub 2003 Jan 9.PMID: 12637985 [PubMed - indexed for MEDLINE]Related articles

Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice.

Shie FS, LeBoeuf RC, Jin LW.

Neuroreport. 2003 Jan 20;14(1):123-9. Erratum in: Neuroreport. 2004 Aug 26;15(12):1993. LeBoeur, Renée C [corrected to LeBoeuf, Renée C]. PMID: 12544843 [PubMed - indexed for MEDLINE]Related articles

Renal injury in apolipoprotein E-deficient mice.

Wen M, Segerer S, Dantas M, Brown PA, Hudkins KL, Goodpaster T, Kirk E, LeBoeuf RC, Alpers CE.

Lab Invest. 2002 Aug;82(8):999-1006.PMID: 12177238 [PubMed - indexed for MEDLINE]Related articles

The murine macrophage apoB-48 receptor gene (Apob-48r): homology to the human receptor.

Brown ML, Yui K, Smith JD, LeBoeuf RC, Weng W, Umeda PK, Li R, Song R, Gianturco SH, Bradley WA.

J Lipid Res. 2002 Aug;43(8):1181-91.PMID: 12177162 [PubMed - indexed for MEDLINE]Related articlesFree article

Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice.

Shie FS, Jin LW, Cook DG, Leverenz JB, LeBoeuf RC.

Neuroreport. 2002 Mar 25;13(4):455-9.PMID: 11930160 [PubMed - indexed for MEDLINE]Related articles

Accumulation of biglycan and perlecan, but not versican, in lesions of murine models of atherosclerosis.

Kunjathoor VV, Chiu DS, O'Brien KD, LeBoeuf RC.

Arterioscler Thromb Vasc Biol. 2002 Mar 1;22(3):462-8.PMID: 11884291 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice.

Schreyer SA, Vick CM, LeBoeuf RC.

J Biol Chem. 2002 Apr 5;277(14):12364-8. Epub 2002 Jan 23.PMID: 11809756 [PubMed - indexed for MEDLINE]Related articlesFree article

LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice.

Schreyer SA, Vick C, Lystig TC, Mystkowski P, LeBoeuf RC.

Am J Physiol Endocrinol Metab. 2002 Jan;282(1):E207-14.PMID: 11739102 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutation of the RIIbeta subunit of protein kinase A prevents diet-induced insulin resistance and dyslipidemia in mice.

Schreyer SA, Cummings DE, McKnight GS, LeBoeuf RC.

Diabetes. 2001 Nov;50(11):2555-62.PMID: 11679434 [PubMed - indexed for MEDLINE]Related articlesFree article

Iron overload diminishes atherosclerosis in apoE-deficient mice.

Kirk EA, Heinecke JW, LeBoeuf RC.

J Clin Invest. 2001 Jun;107(12):1545-53.PMID: 11413162 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased expression of GPI-specific phospholipase D in mouse models of type 1 diabetes.

Deeg MA, Bowen RF, Williams MD, Olson LK, Kirk EA, LeBoeuf RC.

Am J Physiol Endocrinol Metab. 2001 Jul;281(1):E147-54.PMID: 11404232 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of whole-body magnetic resonance spectroscopy as a tool to assess murine body composition.

Mystkowski P, Shankland E, Schreyer SA, LeBoeuf RC, Schwartz RS, Cummings DE, Kushmerick M, Schwartz MW.

Int J Obes Relat Metab Disord. 2000 Jun;24(6):719-24.PMID: 10878678 [PubMed - indexed for MEDLINE]Related articles

Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice.

Kirk EA, Dinauer MC, Rosen H, Chait A, Heinecke JW, LeBoeuf RC.

Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1529-35.PMID: 10845868 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma and vessel wall lipoprotein lipase have different roles in atherosclerosis.

Clee SM, Bissada N, Miao F, Miao L, Marais AD, Henderson HE, Steures P, McManus J, McManus B, LeBoeuf RC, Kastelein JJ, Hayden MR.

J Lipid Res. 2000 Apr;41(4):521-31.PMID: 10744772 [PubMed - indexed for MEDLINE]Related articlesFree article

Initiation of hyperinsulinemia and hyperleptinemia is diet dependent in C57BL/6 mice.

Harte RA, Kirk EA, Rosenfeld ME, LeBoeuf RC.

Horm Metab Res. 1999 Oct;31(10):570-5.PMID: 10596967 [PubMed - indexed for MEDLINE]Related articles

Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice.

Eldar-Finkelman H, Schreyer SA, Shinohara MM, LeBoeuf RC, Krebs EG.

Diabetes. 1999 Aug;48(8):1662-6.PMID: 10426388 [PubMed - indexed for MEDLINE]Related articlesFree article

Murine phospholipid hydroperoxide glutathione peroxidase: cDNA sequence, tissue expression, and mapping.

Knopp EA, Arndt TL, Eng KL, Caldwell M, LeBoeuf RC, Deeb SS, O'Brien KD.

Mamm Genome. 1999 Jun;10(6):601-5.PMID: 10341094 [PubMed - indexed for MEDLINE]Related articles

Dietary antioxidants inhibit development of fatty streak lesions in the LDL receptor-deficient mouse.

Crawford RS, Kirk EA, Rosenfeld ME, LeBoeuf RC, Chait A.

Arterioscler Thromb Vasc Biol. 1998 Sep;18(9):1506-13.PMID: 9743241 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse glycosylphosphatidylinositol-specific phospholipase D (Gpld1) characterization.

LeBoeuf RC, Caldwell M, Guo Y, Metz C, Davitz MA, Olson LK, Deeg MA.

Mamm Genome. 1998 Sep;9(9):710-4.PMID: 9716655 [PubMed - indexed for MEDLINE]Related articles

Obesity and diabetes in TNF-alpha receptor- deficient mice.

Schreyer SA, Chua SC Jr, LeBoeuf RC.

J Clin Invest. 1998 Jul 15;102(2):402-11.PMID: 9664082 [PubMed - indexed for MEDLINE]Related articlesFree article

Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice.

Kirk EA, Sutherland P, Wang SA, Chait A, LeBoeuf RC.

J Nutr. 1998 Jun;128(6):954-9.PMID: 9614153 [PubMed - indexed for MEDLINE]Related articlesFree article

C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis.

Schreyer SA, Wilson DL, LeBoeuf RC.

Atherosclerosis. 1998 Jan;136(1):17-24.PMID: 9544727 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein-binding protein (HBP)/vigilin is expressed in human atherosclerotic lesions and colocalizes with apolipoprotein E.

Chiu DS, Oram JF, LeBoeuf RC, Alpers CE, O'Brien KD.

Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2350-8.PMID: 9409201 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between lipoprotein lipase and high density lipoprotein cholesterol in mice: modulation by cholesteryl ester transfer protein and dietary status.

Clee SM, Zhang H, Bissada N, Miao L, Ehrenborg E, Benlian P, Shen GX, Angel A, LeBoeuf RC, Hayden MR.

J Lipid Res. 1997 Oct;38(10):2079-89.PMID: 9374130 [PubMed - indexed for MEDLINE]Related articlesFree article

Accelerated atherosclerosis in mice lacking tumor necrosis factor receptor p55.

Schreyer SA, Peschon JJ, LeBoeuf RC.

J Biol Chem. 1996 Oct 18;271(42):26174-8.PMID: 8824264 [PubMed - indexed for MEDLINE]Related articlesFree article

High levels of circulating beta-amyloid peptide do not cause cerebral beta-amyloidosis in transgenic mice.

Fukuchi K, Ho L, Younkin SG, Kunkel DD, Ogburn CE, LeBoeuf RC, Furlong CE, Deeb SS, Nochlin D, Wegiel J, Wisniewski HM, Martin GM.

Am J Pathol. 1996 Jul;149(1):219-27.PMID: 8686746 [PubMed - indexed for MEDLINE]Related articlesFree article

Phospholipid transfer protein maps to distal mouse chromosome 2.

LeBoeuf RC, Caldwell M, Tu A, Albers JJ.

Genomics. 1996 Jun 1;34(2):259-60. No abstract available. PMID: 8661063 [PubMed - indexed for MEDLINE]Related articles

Expression of apolipoprotein E inhibits aggregation of the C-terminal fragments of beta-amyloid precursor protein.

Ohman T, Dang N, LeBoeuf RC, Furlong CE, Fukuchi K.

Neurosci Lett. 1996 May 24;210(1):65-8.PMID: 8762193 [PubMed - indexed for MEDLINE]Related articles

Increased atherosclerosis in streptozotocin-induced diabetic mice.

Kunjathoor VV, Wilson DL, LeBoeuf RC.

J Clin Invest. 1996 Apr 1;97(7):1767-73.PMID: 8601643 [PubMed - indexed for MEDLINE]Related articlesFree article