PubMed

In obese and non-obese adults, the cis-regulatory rs361072 promoter variant of PIK3CB is associated with insulin resistance not with type 2 diabetes.

Clément K, Le Stunff C, Meirhaeghe A, Dechartres A, Ferrieres J, Basdevant A, Boitard C, Amouyel P, Bougnères P.

Mol Genet Metab. 2009 Mar;96(3):129-32. Epub 2008 Dec 18.PMID: 19097921 [PubMed - indexed for MEDLINE]Related articles

Endocrine manifestations of the rapid-onset obesity with hypoventilation, hypothalamic, autonomic dysregulation, and neural tumor syndrome in childhood.

Bougnères P, Pantalone L, Linglart A, Rothenbühler A, Le Stunff C.

J Clin Endocrinol Metab. 2008 Oct;93(10):3971-80. Epub 2008 Jul 15.PMID: 18628522 [PubMed - indexed for MEDLINE]Related articlesFree article

Common nonsynonymous variants in PCSK1 confer risk of obesity.

Benzinou M, Creemers JW, Choquet H, Lobbens S, Dina C, Durand E, Guerardel A, Boutin P, Jouret B, Heude B, Balkau B, Tichet J, Marre M, Potoczna N, Horber F, Le Stunff C, Czernichow S, Sandbaek A, Lauritzen T, Borch-Johnsen K, Andersen G, Kiess W, Körner A, Kovacs P, Jacobson P, Carlsson LM, Walley AJ, Jørgensen T, Hansen T, Pedersen O, Meyre D, Froguel P.

Nat Genet. 2008 Aug;40(8):943-5. Epub 2008 Jul 6.PMID: 18604207 [PubMed - indexed for MEDLINE]Related articles

Akt phosphorylation in lymphocytes provides an index of in vitro insulin-like growth factor I sensitivity associated with growth hormone-induced growth.

Lotton C, Rodrigue D, Elie C, Rothenbühler A, Lahlou N, Le Stunff C, Bougnères P.

J Clin Endocrinol Metab. 2008 Apr;93(4):1458-63. Epub 2008 Feb 5.PMID: 18252783 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.

Le Stunff C, Dechartres A, Mariot V, Lotton C, Trainor C, Miraglia Del Giudice E, Meyre D, Bieche I, Laurendeau I, Froguel P, Zelenika D, Fallin D, Lathrop M, Roméo PH, Bougnères P.

Diabetes. 2008 Feb;57(2):494-502. Epub 2007 Oct 31.PMID: 17977952 [PubMed - indexed for MEDLINE]Related articlesFree article

A single-nucleotide polymorphism in the p110beta gene promoter is associated with partial protection from insulin resistance in severely obese adolescents.

Le Stunff C, Dechartres A, Miraglia Del Giudice E, Froguel P, Bougnères P.

J Clin Endocrinol Metab. 2008 Jan;93(1):212-5. Epub 2007 Oct 30.PMID: 17971428 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity.

Ghoussaini M, Vatin V, Lecoeur C, Abkevich V, Younus A, Samson C, Wachter C, Heude B, Tauber M, Tounian P, Hercberg S, Weill J, Levy-Marchal C, Le Stunff C, Bougnères P, Froguel P, Meyre D.

J Clin Endocrinol Metab. 2007 Nov;92(11):4403-9. Epub 2007 Aug 14.PMID: 17698913 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in FTO contributes to childhood obesity and severe adult obesity.

Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P, Carlsson LM, Kiess W, Vatin V, Lecoeur C, Delplanque J, Vaillant E, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Bougnères P, Kovacs P, Marre M, Balkau B, Cauchi S, Chèvre JC, Froguel P.

Nat Genet. 2007 Jun;39(6):724-6. Epub 2007 May 13.PMID: 17496892 [PubMed - indexed for MEDLINE]Related articles

Heterogeneity of class I INS VNTR allele association with insulin secretion in obese children.

Le Fur S, Auffray C, Letourneur F, Cruaud C, Le Stunff C, Bougnères P.

Physiol Genomics. 2006 May 16;25(3):480-4. Epub 2006 Mar 28.PMID: 16569775 [PubMed - indexed for MEDLINE]Related articlesFree article

A homozygous null mutation delineates the role of the melanocortin-4 receptor in humans.

Lubrano-Berthelier C, Le Stunff C, Bougnères P, Vaisse C.

J Clin Endocrinol Metab. 2004 May;89(5):2028-32.PMID: 15126516 [PubMed - indexed for MEDLINE]Related articlesFree article

The common -866 G/A polymorphism in the promoter of uncoupling protein 2 is associated with increased carbohydrate and decreased lipid oxidation in juvenile obesity.

Le Fur S, Le Stunff C, Dos Santos C, Bougnères P.

Diabetes. 2004 Jan;53(1):235-9.PMID: 14693721 [PubMed - indexed for MEDLINE]Related articlesFree article

INS VNTR is a QTL for the insulin response to oral glucose in obese children.

Dos Santos C, Fallin D, Le Stunff C, LeFur S, Bougnères P.

Physiol Genomics. 2004 Feb 13;16(3):309-13.PMID: 14657411 [PubMed - indexed for MEDLINE]Related articles

The human MC4R promoter: characterization and role in obesity.

Lubrano-Berthelier C, Cavazos M, Le Stunff C, Haas K, Shapiro A, Zhang S, Bougneres P, Vaisse C.

Diabetes. 2003 Dec;52(12):2996-3000.PMID: 14633862 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased insulin resistance in obese children who have both 972 IRS-1 and 1057 IRS-2 polymorphisms.

Le Fur S, Le Stunff C, Bougnères P.

Diabetes. 2002 Dec;51 Suppl 3:S304-7.PMID: 12475767 [PubMed - indexed for MEDLINE]Related articlesFree article

[Glycemic anomalies observed in obese adolescents]

Lefèvre H, Le Stunff C, Bougnères PF.

Journ Annu Diabetol Hotel Dieu. 2001:159-63. Review. French. No abstract available. PMID: 11565458 [PubMed - indexed for MEDLINE]Related articles

Paternal transmission of the very common class I INS VNTR alleles predisposes to childhood obesity.

Le Stunff C, Fallin D, Bougnères P.

Nat Genet. 2001 Sep;29(1):96-9.PMID: 11528401 [PubMed - indexed for MEDLINE]Related articles

A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls.

Le Stunff C, Le Bihan C, Schork NJ, Bougnères P.

Diabetes. 2000 Dec;49(12):2196-200.PMID: 11118025 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.

Le Stunff C, Fallin D, Schork NJ, Bougnères P.

Nat Genet. 2000 Dec;26(4):444-6. Erratum in: Nat Genet 2001 May;28(1):97. PMID: 11101842 [PubMed - indexed for MEDLINE]Related articles

Resistance to the lipolytic action of epinephrine: a new feature of protein Gs deficiency.

Carel JC, Le Stunff C, Condamine L, Mallet E, Chaussain JL, Adnot P, Garabédian M, Bougnères P.

J Clin Endocrinol Metab. 1999 Nov;84(11):4127-31.PMID: 10566660 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth hormone stimulates interferon regulatory factor-1 gene expression in the liver.

Le Stunff C, Rotwein P.

Endocrinology. 1998 Mar;139(3):859-66.PMID: 9492014 [PubMed - indexed for MEDLINE]Related articlesFree article

PEG1 expression in maternal uniparental disomy 7.

Cuisset L, Le Stunff C, Dupont JM, Vasseur C, Cartigny M, Despert F, Delpech M, Bougnere P, Jeanpierre M.

Ann Genet. 1997;40(4):211-5.PMID: 9526615 [PubMed - indexed for MEDLINE]Related articles

Contrasting acute in vivo nuclear actions of growth hormone and prolactin.

Le Stunff C, Gronowski AM, Rotwein P.

Mol Cell Endocrinol. 1996 Aug 9;121(2):109-17.PMID: 8892312 [PubMed - indexed for MEDLINE]Related articles

Acute nuclear actions of growth hormone (GH): cycloheximide inhibits inducible activator protein-1 activity, but does not block GH-regulated signal transducer and activator of transcription activation or gene expression.

Gronowski AM, Le Stunff C, Rotwein P.

Endocrinology. 1996 Jan;137(1):55-64.PMID: 8536642 [PubMed - indexed for MEDLINE]Related articles

Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no changes in deoxyribonucleic acid-protein interactions within the second promoter.

Le Stunff C, Thomas MJ, Rotwein P.

Endocrinology. 1995 May;136(5):2230-7.PMID: 7720672 [PubMed - indexed for MEDLINE]Related articles

[Precocious metabolic defects in juvenile obesity]

Bougnères P, Le Stunff C.

Journ Annu Diabetol Hotel Dieu. 1995:147-55. Review. French. No abstract available. PMID: 7602877 [PubMed - indexed for MEDLINE]Related articles

Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity.

Le Stunff C, Bougnères P.

Diabetes. 1994 May;43(5):696-702.PMID: 8168647 [PubMed - indexed for MEDLINE]Related articles

Time course of increased lipid and decreased glucose oxidation during early phase of childhood obesity.

Le Stunff C, Bougnères PF.

Diabetes. 1993 Jul;42(7):1010-6.PMID: 8513968 [PubMed - indexed for MEDLINE]Related articles

Glycerol production and utilization during the early phase of human obesity.

Le Stunff C, Bougnères PF.

Diabetes. 1992 Apr;41(4):444-50.PMID: 1607071 [PubMed - indexed for MEDLINE]Related articles