PubMed

Atrial natriuretic peptide promotes pancreatic islet beta-cell growth and Akt/Foxo1a/cyclin D2 signaling.

You H, Laychock SG.

Endocrinology. 2009 Dec;150(12):5455-65. Epub 2009 Oct 16.PMID: 19837876 [PubMed - in process]Related articles

Metabolic programming: Role of nutrition in the immediate postnatal life.

Patel MS, Srinivasan M, Laychock SG.

J Inherit Metab Dis. 2009 Apr;32(2):218-28. Epub 2008 Dec 22. Review.PMID: 19096914 [PubMed - indexed for MEDLINE]Related articles

Regulated insulin delivery from human epidermal cells reverses hyperglycemia.

Tian J, Lei P, Laychock SG, Andreadis ST.

Mol Ther. 2008 Jun;16(6):1146-53. Epub 2008 Apr 22.PMID: 18431361 [PubMed - indexed for MEDLINE]Related articles

Efficient production of bioactive insulin from human epidermal keratinocytes and tissue-engineered skin substitutes: implications for treatment of diabetes.

Lei P, Ogunade A, Kirkwood KL, Laychock SG, Andreadis ST.

Tissue Eng. 2007 Aug;13(8):2119-31.PMID: 17518716 [PubMed - indexed for MEDLINE]Related articles

Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells.

Laychock SG, Sessanna SM, Lin MH, Mastrandrea LD.

Endocrinology. 2006 Oct;147(10):4705-12. Epub 2006 Jun 22.PMID: 16794003 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutrient-induced maternal hyperinsulinemia and metabolic programming in the progeny.

Patel MS, Srinivasan M, Laychock SG.

Nestle Nutr Workshop Ser Pediatr Program. 2005;55:137-47; discussion 147-51. Review. No abstract available. PMID: 16632932 [PubMed - indexed for MEDLINE]Related articles

Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells: response to cytokines.

Mastrandrea LD, Sessanna SM, Laychock SG.

Diabetes. 2005 May;54(5):1429-36.PMID: 15855330 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells.

Laychock SG, Tian Y, Sessanna SM.

Diabetes. 2003 Aug;52(8):1986-93.PMID: 12882914 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolactin regulates adenylyl cyclase and insulin secretion in rat pancreatic islets.

Tian Y, Laychock SG.

Mol Cell Endocrinol. 2003 Jun 30;204(1-2):75-84.PMID: 12850283 [PubMed - indexed for MEDLINE]Related articles

Role of nerve growth factor in the regulation of parotid cell differentiation induced by rat serum.

Takeuchi T, Aletta JM, Laychock SG, Tian Y, Rubin RP.

Biochem Pharmacol. 2003 May 1;65(9):1507-13.PMID: 12732363 [PubMed - indexed for MEDLINE]Related articles

Neonatal nutrition: metabolic programming of pancreatic islets and obesity.

Srinivasan M, Laychock SG, Hill DJ, Patel MS.

Exp Biol Med (Maywood). 2003 Jan;228(1):15-23. Review.PMID: 12524468 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression and cellular localization of a modified type 1 ryanodine receptor and L-type channel proteins in non-muscle cells.

Lee BS, Sessanna S, Laychock SG, Rubin RP.

J Membr Biol. 2002 Oct 1;189(3):181-90.PMID: 12395283 [PubMed - indexed for MEDLINE]Related articles

Protein kinase C and calcium regulation of adenylyl cyclase in isolated rat pancreatic islets.

Tian Y, Laychock SG.

Diabetes. 2001 Nov;50(11):2505-13.PMID: 11679428 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets.

Lee B, Gai W, Laychock SG.

Endocrinology. 2001 May;142(5):1744-51.PMID: 11316737 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial-encoded gene regulation in rat pancreatic islets.

Lee B, Srinivasan M, Aalinkeel R, Patel MS, Laychock SG.

Metabolism. 2001 Feb;50(2):200-6.PMID: 11229430 [PubMed - indexed for MEDLINE]Related articles

Inositol 1,4,5-trisphosphate receptor isoform expression in mouse pancreatic islets: effects of carbachol.

Lee B, Laychock SG.

Biochem Pharmacol. 2001 Feb 1;61(3):327-36.PMID: 11172737 [PubMed - indexed for MEDLINE]Related articles

Adaptive changes in insulin secretion by islets from neonatal rats raised on a high-carbohydrate formula.

Srinivasan M, Aalinkeel R, Song F, Lee B, Laychock SG, Patel MS.

Am J Physiol Endocrinol Metab. 2000 Dec;279(6):E1347-57.PMID: 11093923 [PubMed - indexed for MEDLINE]Related articlesFree article

Metallothionein induction in islets of Langerhans and insulinoma cells.

Laychock SG, Duzen J, Simpkins CO.

Mol Cell Endocrinol. 2000 Jul 25;165(1-2):179-87.PMID: 10940496 [PubMed - indexed for MEDLINE]Related articles

Determination of NOS activity using cyclic-GMP formation.

Laychock SG.

Methods Mol Biol. 1998;100:93-100. No abstract available. PMID: 10906997 [PubMed - indexed for MEDLINE]Related articles

Regulation of inositol trisphosphate receptor isoform expression in glucose-desensitized rat pancreatic islets: role of cyclic adenosine 3',5'-monophosphate and calcium.

Lee B, Laychock SG.

Endocrinology. 2000 Apr;141(4):1394-402.PMID: 10746643 [PubMed - indexed for MEDLINE]Related articlesFree article

A dietary intervention (high carbohydrate) during the neonatal period causes islet dysfunction in rats.

Aalinkeel R, Srinivasan M, Kalhan SC, Laychock SG, Patel MS.

Am J Physiol. 1999 Dec;277(6 Pt 1):E1061-9.PMID: 10600796 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulates expression of inositol 1,4,5-trisphosphate receptor isoforms in isolated rat pancreatic islets.

Lee B, Jonas JC, Weir GC, Laychock SG.

Endocrinology. 1999 May;140(5):2173-82.PMID: 10218969 [PubMed - indexed for MEDLINE]Related articlesFree article

Rat pancreatic islet and RINm5F cell responses to epiandrosterone, dehydroepiandrosterone and interleukin-1 beta.

Laychock SG.

Biochem Pharmacol. 1998 May 1;55(9):1453-64.PMID: 10076538 [PubMed - indexed for MEDLINE]Related articles

A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1beta.

Ye J, Laychock SG.

Endocrinology. 1998 Oct;139(10):4155-63.PMID: 9751495 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of inositol 1,4,5-trisphosphate receptor isoform mRNA expression and regulation in rat pancreatic islets, RINm5F cells and betaHC9 cells.

Lee B, Bradford PG, Laychock SG.

J Mol Endocrinol. 1998 Aug;21(1):31-9.PMID: 9723861 [PubMed - indexed for MEDLINE]Related articlesFree article

Atrial natriuretic peptide and cyclic nucleotides affect glucose-induced Ca2+ responses in single pancreatic islet beta-cells: correlation with (Ca[2+] + Mg2+)-ATPase activity.

Lee B, Laychock SG.

Diabetes. 1997 Aug;46(8):1312-8.PMID: 9231656 [PubMed - indexed for MEDLINE]Related articles

Modulation of glyceraldehyde 3-phosphate dehydrogenase activity in isolated pancreatic islets.

Laychock SG.

Biochem Pharmacol. 1996 Sep 13;52(5):793-9.PMID: 8765477 [PubMed - indexed for MEDLINE]Related articles

Epiandrosterone and dehydroepiandrosterone affect glucose oxidation and interleukin-1 beta effects in pancreatic islets.

Laychock SG, Bauer AL.

Endocrinology. 1996 Aug;137(8):3375-85.PMID: 8754764 [PubMed - indexed for MEDLINE]Related articles

Neonatal rat dietary carbohydrate affects pancreatic islet insulin secretion in adults and progeny.

Laychock SG, Vadlamudi S, Patel MS.

Am J Physiol. 1995 Oct;269(4 Pt 1):E739-44.PMID: 7485489 [PubMed - indexed for MEDLINE]Related articles

Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets.

Laychock SG.

Mol Cell Endocrinol. 1995 Aug 30;113(1):19-28.PMID: 8674810 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide reduces depolarization-induced calcium influx in PC12 cells by a cyclic GMP-mediated mechanism.

Desole MS, Kim WK, Rabin RA, Laychock SG.

Neuropharmacology. 1994 Feb;33(2):193-8.PMID: 8035903 [PubMed - indexed for MEDLINE]Related articles

Evidence for a cannabinoid receptor in sea urchin sperm and its role in blockade of the acrosome reaction.

Chang MC, Berkery D, Schuel R, Laychock SG, Zimmerman AM, Zimmerman S, Schuel H.

Mol Reprod Dev. 1993 Dec;36(4):507-16.PMID: 8305215 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets.

Xia M, Laychock SG.

Diabetes. 1993 Oct;42(10):1392-400.PMID: 8397125 [PubMed - indexed for MEDLINE]Related articles

Sp-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-cyclic monophosphorothioate is a potent stimulus for insulin release.

Laychock SG.

Endocr Res. 1993;19(2-3):113-22.PMID: 8287829 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol availability and polyphosphoinositide synthesis in pancreatic islet cell membranes.

Khalaf LJ, Laychock SG.

Biochem Pharmacol. 1992 Mar 17;43(6):1303-10.PMID: 1314058 [PubMed - indexed for MEDLINE]Related articles

L-arginine stimulates cyclic guanosine 3',5'-monophosphate formation in rat islets of Langerhans and RINm5F insulinoma cells: evidence for L-arginine:nitric oxide synthase.

Laychock SG, Modica ME, Cavanaugh CT.

Endocrinology. 1991 Dec;129(6):3043-52.PMID: 1683279 [PubMed - indexed for MEDLINE]Related articles

Comparative effects of epidermal growth factor and carbachol on phosphoinositide synthesis and breakdown in pancreatic acinar cells.

Conway BR, Laychock SG, Rubin RP.

Biochem Biophys Res Commun. 1991 Jul 31;178(2):780-5.PMID: 1650199 [PubMed - indexed for MEDLINE]Related articles

Reduction of the fertilizing capacity of sea urchin sperm by cannabinoids derived from marihuana. III. Activation of phospholipase A2 in sperm homogenate by delta 9-tetrahydrocannabinol.

Chang MC, Berkery D, Laychock SG, Schuel H.

Biochem Pharmacol. 1991 Jul 25;42(4):899-904.PMID: 1651081 [PubMed - indexed for MEDLINE]Related articles

Modulation of phospholipase A2 activity in zymogen granule membranes by GTP[S]; evidence for GTP-binding protein regulation.

Rubin RP, Withiam-Leitch M, Laychock SG.

Biochem Biophys Res Commun. 1991 May 31;177(1):22-6.PMID: 1904217 [PubMed - indexed for MEDLINE]Related articles

Characterization of phospholipase A2 and acyltransferase activities in purified zymogen granule membranes.

Rubin RP, Thompson RH, Laychock SG.

Biochim Biophys Acta. 1990 Aug 6;1045(3):245-51.PMID: 2386797 [PubMed - indexed for MEDLINE]Related articles

Fatty acids and cyclooxygenase and lipoxygenase pathway inhibitors modulate inositol phosphate formation in pancreatic islets.

Laychock SG.

Mol Pharmacol. 1990 Jun;37(6):928-36.PMID: 2113605 [PubMed - indexed for MEDLINE]Related articles

Glucose metabolism, second messengers and insulin secretion.

Laychock SG.

Life Sci. 1990;47(25):2307-16. Review.PMID: 2175823 [PubMed - indexed for MEDLINE]Related articles

Calcium mobilization, prostaglandin E2 and alpha 2-adrenoceptor modulation of glucose utilization and insulin secretion in pancreatic islets.

Laychock SG, Bilgin S.

Biochem Pharmacol. 1989 Aug 1;38(15):2511-20.PMID: 2547383 [PubMed - indexed for MEDLINE]Related articles

Analysis of the regulation of phosphatidylinositol-4,5-bisphosphate synthesis by arachidonic acid in exocrine pancreas.

Chaudhry A, Conway BR, Laychock SG, Rubin RP.

Arch Biochem Biophys. 1989 Aug 1;272(2):488-95.PMID: 2546502 [PubMed - indexed for MEDLINE]Related articles

Prostaglandin E2 inhibits phosphoinositide metabolism in isolated pancreatic islets.

Laychock SG.

Biochem J. 1989 May 15;260(1):291-4.PMID: 2549955 [PubMed - indexed for MEDLINE]Related articlesFree article

Prostaglandin E2 and alpha 2 adrenoceptor agonists inhibit the pentose phosphate shunt in pancreatic islets.

Laychock SG.

Arch Biochem Biophys. 1989 Feb 15;269(1):354-8.PMID: 2563646 [PubMed - indexed for MEDLINE]Related articles

Coordinate interactions of cyclic nucleotide and phospholipid metabolizing pathways in calcium-dependent cellular processes.

Laychock SG.

Curr Top Cell Regul. 1989;30:203-42. Review.PMID: 2559830 [PubMed - indexed for MEDLINE]Related articles

Choline turnover in phosphatidylcholine of pancreatic islets. Implications for CDP-choline pathway.

Hoffman JM, Laychock SG.

Diabetes. 1988 Nov;37(11):1489-98.PMID: 2846391 [PubMed - indexed for MEDLINE]Related articles

Relationship between delta-9-tetrahydrocannabinol-induced arachidonic acid release and secretagogue-evoked phosphoinositide breakdown and Ca2+ mobilization of exocrine pancreas.

Chaudhry A, Thompson RH, Rubin RP, Laychock SG.

Mol Pharmacol. 1988 Oct;34(4):543-8.PMID: 2459592 [PubMed - indexed for MEDLINE]Related articles

Biosynthesis of peptidyl leukotrienes and other lipoxygenase products by rat pancreatic islets. Comparison with macrophages and neutrophils.

Morgan RO, Laychock SG.

Prostaglandins. 1988 Apr;35(4):609-23.PMID: 3150114 [PubMed - indexed for MEDLINE]Related articles