PubMed

Increased tumor necrosis factor alpha-converting enzyme activity induces insulin resistance and hepatosteatosis in mice.

Fiorentino L, Vivanti A, Cavalera M, Marzano V, Ronci M, Fabrizi M, Menini S, Pugliese G, Menghini R, Khokha R, Lauro R, Urbani A, Federici M.

Hepatology. 2009 Aug 25. [Epub ahead of print]PMID: 19877183 [PubMed - as supplied by publisher]Related articles

MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1.

Menghini R, Casagrande V, Cardellini M, Martelli E, Terrinoni A, Amati F, Vasa-Nicotera M, Ippoliti A, Novelli G, Melino G, Lauro R, Federici M.

Circulation. 2009 Oct 13;120(15):1524-32. Epub 2009 Sep 28.PMID: 19786632 [PubMed - indexed for MEDLINE]Related articles

[Diabetes worsens the clinical manifestations and prognosis of concurrent cardiovascular and kidney disease]

Leo R, Tesauro M, Forleo GB, Razzini C, Romeo F, Lauro R.

G Ital Nefrol. 2009 Jul-Aug;26 Suppl 46:71-8. Italian. PMID: 19644822 [PubMed - in process]Related articles

[Endothelial dysfunction and diabetes: possible role in kidney damage]

Tesauro M, Leo R, Lauro R, Cardillo C.

G Ital Nefrol. 2009 Jul-Aug;26 Suppl 46:62-70. Italian. PMID: 19644821 [PubMed - in process]Related articles

TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1.

Cardellini M, Menghini R, Martelli E, Casagrande V, Marino A, Rizza S, Porzio O, Mauriello A, Solini A, Ippoliti A, Lauro R, Folli F, Federici M.

Diabetes. 2009 Oct;58(10):2396-401. Epub 2009 Jul 6.PMID: 19581416 [PubMed - indexed for MEDLINE]Related articles

Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis.

Succurro E, Marini MA, Arturi F, Grembiale A, Lugarà M, Andreozzi F, Sciacqua A, Lauro R, Hribal ML, Perticone F, Sesti G.

Atherosclerosis. 2009 Nov;207(1):245-9. Epub 2009 Apr 11.PMID: 19410252 [PubMed - in process]Related articles

Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects.

Succurro E, Andreozzi F, Marini MA, Lauro R, Hribal ML, Perticone F, Sesti G.

Nutr Metab Cardiovasc Dis. 2009 Dec;19(10):713-9. Epub 2009 Apr 5.PMID: 19346116 [PubMed - in process]Related articles

Differences in cardiovascular risk profile based on relationship between post-load plasma glucose and fasting plasma levels.

Succurro E, Marini MA, Grembiale A, Lugarà M, Andreozzi F, Sciacqua A, Hribal ML, Lauro R, Perticone F, Sesti G.

Diabetes Metab Res Rev. 2009 May;25(4):351-6.PMID: 19319930 [PubMed - indexed for MEDLINE]Related articles

Oncogenic ras blocks the cAMP pathway and dedifferentiates thyroid cells via an impairment of pax8 transcriptional activity.

Baratta MG, Porreca I, Di Lauro R.

Mol Endocrinol. 2009 Jun;23(6):838-48. Epub 2009 Mar 12.PMID: 19282367 [PubMed - indexed for MEDLINE]Related articles

"The Linosa Study": epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate.

Bellia A, Giardina E, Lauro D, Tesauro M, Di Fede G, Cusumano G, Federici M, Rini GB, Novelli G, Lauro R, Sbraccia P.

Nutr Metab Cardiovasc Dis. 2009 Sep;19(7):455-61. Epub 2009 Feb 6.PMID: 19201175 [PubMed - indexed for MEDLINE]Related articles

IL-18 gene polymorphism and metabolic syndrome.

Presta I, Andreozzi F, Succurro E, Marini MA, Laratta E, Lauro R, Hribal ML, Perticone F, Sesti G.

Nutr Metab Cardiovasc Dis. 2009 Feb;19(2):e5-6. Epub 2009 Jan 26. No abstract available. PMID: 19176284 [PubMed - indexed for MEDLINE]Related articles

Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice.

Menghini R, Menini S, Amoruso R, Fiorentino L, Casagrande V, Marzano V, Tornei F, Bertucci P, Iacobini C, Serino M, Porzio O, Hribal ML, Folli F, Khokha R, Urbani A, Lauro R, Pugliese G, Federici M.

Gastroenterology. 2009 Feb;136(2):663-72.e4. Epub 2008 Nov 6.PMID: 19027012 [PubMed - indexed for MEDLINE]Related articles

An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation.

Talotta F, Cimmino A, Matarazzo MR, Casalino L, De Vita G, D'Esposito M, Di Lauro R, Verde P.

Oncogene. 2009 Jan 8;28(1):73-84. Epub 2008 Oct 13.PMID: 18850008 [PubMed - indexed for MEDLINE]Related articles

The role of Humphrey Matrix testing in the early diagnosis of retinopathy in type 1 diabetes.

Parravano M, Oddone F, Mineo D, Centofanti M, Borboni P, Lauro R, Tanga L, Manni G.

Br J Ophthalmol. 2008 Dec;92(12):1656-60. Epub 2008 Oct 1.PMID: 18829632 [PubMed - indexed for MEDLINE]Related articles

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

To MD, Wong CE, Karnezis AN, Del Rosario R, Di Lauro R, Balmain A.

Nat Genet. 2008 Oct;40(10):1240-4. Epub 2008 Aug 31.PMID: 18758463 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals.

Succurro E, Marini MA, Frontoni S, Hribal ML, Andreozzi F, Lauro R, Perticone F, Sesti G.

Obesity (Silver Spring). 2008 Aug;16(8):1881-6. Epub 2008 Jun 12.PMID: 18551117 [PubMed - indexed for MEDLINE]Related articles

Adiponectin isoforms are not associated with the severity of coronary atherosclerosis but with undiagnosed diabetes in patients affected by stable CAD.

Rizza S, Clementi F, Porzio O, Cardellini M, Savo A, Serino M, Chiricolo G, Romeo F, Lauro R, Federici M.

Nutr Metab Cardiovasc Dis. 2009 Jan;19(1):54-60. Epub 2008 May 9.PMID: 18472407 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance affects gene expression in endothelium.

Consoli C, Martelli E, D'Adamo M, Menghini R, Arcelli D, Porzio O, Pandolfi A, Pistolese GR, Consoli A, Lauro R, Ippoliti A, Federici M.

Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):e7-9. No abstract available. PMID: 18216326 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion.

Hribal ML, Tornei F, Pujol A, Menghini R, Barcaroli D, Lauro D, Amoruso R, Lauro R, Bosch F, Sesti G, Federici M.

J Cell Mol Med. 2008 Oct;12(5B):2096-106. Epub 2008 Jan 19.PMID: 18208559 [PubMed - indexed for MEDLINE]Related articles

The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.

Errico F, Santini E, Migliarini S, Borgkvist A, Centonze D, Nasti V, Carta M, De Chiara V, Prosperetti C, Spano D, Herve D, Pasqualetti M, Di Lauro R, Fisone G, Usiello A.

Mol Cell Neurosci. 2008 Feb;37(2):335-45. Epub 2007 Oct 23.PMID: 18035555 [PubMed - indexed for MEDLINE]Related articles

Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility.

Errico F, Nisticò R, Palma G, Federici M, Affuso A, Brilli E, Topo E, Centonze D, Bernardi G, Bozzi Y, D'Aniello A, Di Lauro R, Mercuri NB, Usiello A.

Mol Cell Neurosci. 2008 Feb;37(2):236-46. Epub 2007 Oct 5.PMID: 17981050 [PubMed - indexed for MEDLINE]Related articles

Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome.

Scuteri A, Tesauro M, Rizza S, Iantorno M, Federici M, Lauro D, Campia U, Turriziani M, Fusco A, Cocciolillo G, Lauro R.

Nutr Metab Cardiovasc Dis. 2008 Jun;18(5):349-56. Epub 2007 Nov 1.PMID: 17935958 [PubMed - indexed for MEDLINE]Related articles

Murine models for the study of thyroid gland development.

De Felice M, Di Lauro R.

Endocr Dev. 2007;10:1-14. Review.PMID: 17684386 [PubMed - indexed for MEDLINE]Related articles

Mice heterozygous for tumor necrosis factor-alpha converting enzyme are protected from obesity-induced insulin resistance and diabetes.

Serino M, Menghini R, Fiorentino L, Amoruso R, Mauriello A, Lauro D, Sbraccia P, Hribal ML, Lauro R, Federici M.

Diabetes. 2007 Oct;56(10):2541-6. Epub 2007 Jul 23.PMID: 17646208 [PubMed - indexed for MEDLINE]Related articlesFree article

A mammalian microRNA expression atlas based on small RNA library sequencing.

Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foà R, Schliwka J, Fuchs U, Novosel A, Müller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G, Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN, Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo JJ, Sander C, Zavolan M, Tuschl T.

Cell. 2007 Jun 29;129(7):1401-14.PMID: 17604727 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolically healthy but obese women have an intermediate cardiovascular risk profile between healthy nonobese women and obese insulin-resistant women.

Marini MA, Succurro E, Frontoni S, Hribal ML, Andreozzi F, Lauro R, Perticone F, Sesti G.

Diabetes Care. 2007 Aug;30(8):2145-7. Epub 2007 May 16. No abstract available. PMID: 17507694 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin glargine in enteric tube feeding.

Marchetti G, Tesauro M, Di Daniele N, Bollea MR, Lauro R, Bertoli A.

Diabetes Res Clin Pract. 2007 Nov;78(2):298-9. Epub 2007 May 3. No abstract available. PMID: 17481764 [PubMed - indexed for MEDLINE]Related articles

Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation.

Calì G, Zannini M, Rubini P, Tacchetti C, D'Andrea B, Affuso A, Wintermantel T, Boussadia O, Terracciano D, Silberschmidt D, Amendola E, De Felice M, Schütz G, Kemler R, Di Lauro R, Nitsch L.

Endocrinology. 2007 Jun;148(6):2737-46. Epub 2007 Mar 8.PMID: 17347311 [PubMed - indexed for MEDLINE]Related articlesFree article

Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.

Milenkovic M, De Deken X, Jin L, De Felice M, Di Lauro R, Dumont JE, Corvilain B, Miot F.

J Endocrinol. 2007 Mar;192(3):615-26.PMID: 17332529 [PubMed - indexed for MEDLINE]Related articlesFree article

Further evidence that polymorphisms of the OLR1 gene are associated with susceptibility to coronary artery disease and myocardial infarction.

Novelli G, Borgiani P, Mango R, Lauro R, Romeo F.

Nutr Metab Cardiovasc Dis. 2007 Mar;17(3):e7-8; author reply e9-10. Epub 2007 Feb 26. No abstract available. PMID: 17321727 [PubMed - indexed for MEDLINE]Related articles

Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus.

Tesauro M, Rizza S, Iantorno M, Campia U, Cardillo C, Lauro D, Leo R, Turriziani M, Cocciolillo GC, Fusco A, Panza JA, Scuteri A, Federici M, Lauro R, Quon MJ.

Metabolism. 2007 Mar;56(3):413-9.PMID: 17292732 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

D'Alessandris C, Lauro R, Presta I, Sesti G.

Diabetologia. 2007 Apr;50(4):840-9. Epub 2007 Feb 6.PMID: 17279354 [PubMed - indexed for MEDLINE]Related articles

Association between enhanced soluble CD40 ligand and proinflammatory and prothrombotic states in major depressive disorder: pilot observations on the effects of selective serotonin reuptake inhibitor therapy.

Leo R, Di Lorenzo G, Tesauro M, Razzini C, Forleo GB, Chiricolo G, Cola C, Zanasi M, Troisi A, Siracusano A, Lauro R, Romeo F.

J Clin Psychiatry. 2006 Nov;67(11):1760-6.PMID: 17196057 [PubMed - indexed for MEDLINE]Related articles

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage.

Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T.

J Biol Chem. 2007 Jan 12;282(2):831-5. Epub 2006 Nov 22.PMID: 17121854 [PubMed - indexed for MEDLINE]Related articlesFree article

PAX8 expression in human bladder cancer.

Pellizzari L, Puppin C, Mariuzzi L, Saro F, Pandolfi M, Di Lauro R, Beltrami CA, Damante G.

Oncol Rep. 2006 Nov;16(5):1015-20.PMID: 17016586 [PubMed - indexed for MEDLINE]Related articles

Decreased plasma adiponectin concentration in major depression.

Leo R, Di Lorenzo G, Tesauro M, Cola C, Fortuna E, Zanasi M, Troisi A, Siracusano A, Lauro R, Romeo F.

Neurosci Lett. 2006 Oct 30;407(3):211-3. Epub 2006 Sep 14.PMID: 16973279 [PubMed - indexed for MEDLINE]Related articles

Plasma interleukin-6 levels are increased in subjects with impaired glucose tolerance but not in those with impaired fasting glucose in a cohort of Italian Caucasians.

Cardellini M, Andreozzi F, Laratta E, Marini MA, Lauro R, Hribal ML, Perticone F, Sesti G.

Diabetes Metab Res Rev. 2007 Feb;23(2):141-5.PMID: 16952201 [PubMed - indexed for MEDLINE]Related articles

Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling.

Marchetti V, Menghini R, Rizza S, Vivanti A, Feccia T, Lauro D, Fukamizu A, Lauro R, Federici M.

Diabetes. 2006 Aug;55(8):2231-7.PMID: 16873685 [PubMed - indexed for MEDLINE]Related articlesFree article

Concomitant impairment in endothelial function and neural cardiovascular regulation in offspring of type 2 diabetic subjects.

Iellamo F, Tesauro M, Rizza S, Aquilani S, Cardillo C, Iantorno M, Turriziani M, Lauro R.

Hypertension. 2006 Sep;48(3):418-23. Epub 2006 Jul 24.PMID: 16864746 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma interleukin-6 levels are independently associated with insulin secretion in a cohort of Italian-Caucasian nondiabetic subjects.

Andreozzi F, Laratta E, Cardellini M, Marini MA, Lauro R, Hribal ML, Perticone F, Sesti G.

Diabetes. 2006 Jul;55(7):2021-4.PMID: 16804071 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in caucasian italian subjects.

Scarpelli D, Cardellini M, Andreozzi F, Laratta E, Hribal ML, Marini MA, Tassi V, Lauro R, Perticone F, Sesti G.

Diabetes. 2006 May;55(5):1529-33.PMID: 16644716 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction.

D'Andrea B, Iacone R, Di Palma T, Nitsch R, Baratta MG, Nitsch L, Di Lauro R, Zannini M.

Mol Endocrinol. 2006 Aug;20(8):1810-24. Epub 2006 Apr 13.PMID: 16613988 [PubMed - indexed for MEDLINE]Related articlesFree article

The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

Sesti G, Laratta E, Cardellini M, Andreozzi F, Del Guerra S, Irace C, Gnasso A, Grupillo M, Lauro R, Hribal ML, Perticone F, Marchetti P.

J Clin Endocrinol Metab. 2006 Jun;91(6):2334-9. Epub 2006 Apr 4.PMID: 16595597 [PubMed - indexed for MEDLINE]Related articlesFree article

A physiological mechanism to regulate D-aspartic acid and NMDA levels in mammals revealed by D-aspartate oxidase deficient mice.

Errico F, Pirro MT, Affuso A, Spinelli P, De Felice M, D'Aniello A, Di Lauro R.

Gene. 2006 Jun 7;374:50-7. Epub 2006 Mar 3.PMID: 16516413 [PubMed - indexed for MEDLINE]Related articles

Is reduced baroreflex gain a component of the metabolic syndrome? Insights from the LINOSA study.

Lucini D, Cusumano G, Bellia A, Kozakova M, Difede G, Lauro R, Pagani M; for the Linosa Study Group.

J Hypertens. 2006 Feb;24(2):361-70.PMID: 16508585 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and increased intimal medial thickness in glucose tolerant offspring of type 2 diabetic subjects carrying the D298D genotype of endothelial nitric oxide synthase.

Rizza S, Tesauro M, Cardellini M, Menghini R, Bellia A, Marini MA, Lauro D, Sbraccia P, Sesti G, Lauro R, Federici M.

Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):431-2. No abstract available. PMID: 16424363 [PubMed - indexed for MEDLINE]Related articlesFree article

Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.

Dentice M, Cordeddu V, Rosica A, Ferrara AM, Santarpia L, Salvatore D, Chiovato L, Perri A, Moschini L, Fazzini C, Olivieri A, Costa P, Stoppioni V, Baserga M, De Felice M, Sorcini M, Fenzi G, Di Lauro R, Tartaglia M, Macchia PE.

J Clin Endocrinol Metab. 2006 Apr;91(4):1428-33. Epub 2006 Jan 17.PMID: 16418214 [PubMed - indexed for MEDLINE]Related articlesFree article

Nontraumatic abdominal hemorrhage: MDCTA.

Lemos AA, Sternberg JM, Tognini L, Lauro R, Biondetti PR.

Abdom Imaging. 2006 Jan-Feb;31(1):17-24. No abstract available. PMID: 16333705 [PubMed - indexed for MEDLINE]Related articles

Pharmacogenomics in cardiovascular disease: the role of single nucleotide polymorphisms in improving drug therapy.

Mango R, Vecchione L, Raso B, Borgiani P, Brunetti E, Mehta JL, Lauro R, Romeo F, Novelli G.

Expert Opin Pharmacother. 2005 Dec;6(15):2565-76. Review.PMID: 16316297 [PubMed - indexed for MEDLINE]Related articles

Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha.

Federici M, Hribal ML, Menghini R, Kanno H, Marchetti V, Porzio O, Sunnarborg SW, Rizza S, Serino M, Cunsolo V, Lauro D, Mauriello A, Smookler DS, Sbraccia P, Sesti G, Lee DC, Khokha R, Accili D, Lauro R.

J Clin Invest. 2005 Dec;115(12):3494-505. Epub 2005 Nov 17.PMID: 16294222 [PubMed - indexed for MEDLINE]Related articlesFree article