PubMed

Minimal residual disease and normalization of the bone marrow after long-term treatment with alpha-interferon2b in polycythemia vera. A report on molecular response patterns in seven patients in sustained complete hematological remission.

Larsen TS, Møller MB, de Stricker K, Nørgaard P, Samuelsson J, Marcher C, Andersen MT, Bjerrum OW, Hasselbalch HC.

Hematology. 2009 Dec;14(6):331-334.PMID: 19941739 [PubMed - as supplied by publisher]

Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss.

Hafstad AD, Khalid AM, Hagve M, Lund T, Larsen TS, Severson DL, Clarke K, Berge RK, Aasum E.

Cardiovasc Res. 2009 Aug 1;83(3):519-26. Epub 2009 Apr 27.PMID: 19398469 [PubMed - indexed for MEDLINE]Related articles

Increased O2 cost of basal metabolism and excitation-contraction coupling in hearts from type 2 diabetic mice.

Boardman N, Hafstad AD, Larsen TS, Severson DL, Aasum E.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1373-9. Epub 2009 Mar 13.PMID: 19286944 [PubMed - indexed for MEDLINE]Related articles

Inadvertent phosphorylation of survival kinases in isolated perfused hearts: a word of caution.

Stensløkken KO, Rutkovskiy A, Kaljusto ML, Hafstad AD, Larsen TS, Vaage J.

Basic Res Cardiol. 2009 Jul;104(4):412-23. Epub 2009 Feb 6.PMID: 19198917 [PubMed - indexed for MEDLINE]Related articles

Limited efficacy of hydroxyurea in lowering of the JAK2 V617F allele burden.

Larsen TS, Pallisgaard N, de Stricker K, Møller MB, Hasselbalch HC.

Hematology. 2009 Feb;14(1):11-5.PMID: 19154659 [PubMed - indexed for MEDLINE]Related articles

High prevalence of arterial thrombosis in JAK2 mutated essential thrombocythaemia: independence of the V617F allele burden.

Larsen TS, Pallisgaard N, Møller MB, Hasselbalch HC.

Hematology. 2008 Apr;13(2):71-6.PMID: 18616871 [PubMed - indexed for MEDLINE]Related articles

Sustained major molecular response on interferon alpha-2b in two patients with polycythemia vera.

Larsen TS, Bjerrum OW, Pallisgaard N, Andersen MT, Møller MB, Hasselbalch HC.

Ann Hematol. 2008 Oct;87(10):847-50. Epub 2008 May 15.PMID: 18481066 [PubMed - indexed for MEDLINE]Related articles

Non-selective beta-adrenergic blockade prevents reduction of the cerebral metabolic ratio during exhaustive exercise in humans.

Larsen TS, Rasmussen P, Overgaard M, Secher NH, Nielsen HB.

J Physiol. 2008 Jun 1;586(Pt 11):2807-15. Epub 2008 Apr 10.PMID: 18403423 [PubMed - indexed for MEDLINE]Related articlesFree article

[Tyrosine kinase inhibitors in the treatment of polycythemia vera and related conditions. Danish Society of Hematology]

Larsen TS, Hasselbalch HC; Dansk Haematologisk Selskab.

Ugeskr Laeger. 2008 Mar 17;170(12):1031. Danish. No abstract available. PMID: 18397649 [PubMed - indexed for MEDLINE]Related articles

Laparoscopic colonic surgery in Denmark 2004-2007.

Schulze S, Iversen MG, Bendixen A, Larsen TS, Kehlet H.

Colorectal Dis. 2008 Nov;10(9):869-72. Epub 2008 Mar 29.PMID: 18384423 [PubMed - indexed for MEDLINE]Related articles

Metabolic (in)flexibility of the diabetic heart.

Larsen TS, Aasum E.

Cardiovasc Drugs Ther. 2008 Apr;22(2):91-5. Review.PMID: 18247112 [PubMed - indexed for MEDLINE]Related articles

Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness.

Vinge LE, von Lueder TG, Aasum E, Qvigstad E, Gravning JA, How OJ, Edvardsen T, Bjørnerheim R, Ahmed MS, Mikkelsen BW, Oie E, Attramadal T, Skomedal T, Smiseth OA, Koch WJ, Larsen TS, Attramadal H.

J Biol Chem. 2008 Apr 18;283(16):10601-10. Epub 2007 Dec 29.PMID: 18165681 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice.

How OJ, Larsen TS, Hafstad AD, Khalid A, Myhre ES, Murray AJ, Boardman NT, Cole M, Clarke K, Severson DL, Aasum E.

Arch Physiol Biochem. 2007 Oct-Dec;113(4-5):211-20.PMID: 18158644 [PubMed - indexed for MEDLINE]Related articles

The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis--impact on disease phenotype.

Larsen TS, Pallisgaard N, Møller MB, Hasselbalch HC.

Eur J Haematol. 2007 Dec;79(6):508-15. Epub 2007 Oct 23.PMID: 17961178 [PubMed - indexed for MEDLINE]Related articles

Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice.

Aasum E, Khalid AM, Gudbrandsen OA, How OJ, Berge RK, Larsen TS.

J Mol Cell Cardiol. 2008 Jan;44(1):201-9. Epub 2007 Sep 7.PMID: 17931655 [PubMed - indexed for MEDLINE]Related articles

The nature of corticospinal paths driving human motoneurones during voluntary contractions.

Butler JE, Larsen TS, Gandevia SC, Petersen NT.

J Physiol. 2007 Oct 15;584(Pt 2):651-9. Epub 2007 Aug 16.PMID: 17702821 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative assessment of the JAK2 V617F allele burden: equivalent levels in peripheral blood and bone marrow.

Larsen TS, Pallisgaard N, Møller MB, Hasselbalch HC.

Leukemia. 2008 Jan;22(1):194-5. Epub 2007 Jul 12. No abstract available. PMID: 17625603 [PubMed - indexed for MEDLINE]Related articles

[Laparoscopic colorectal surgery in Denmark 2004-2005]

Larsen TS, Schulze S, Kehlet H.

Ugeskr Laeger. 2007 Mar 19;169(12):1089-91. Danish. PMID: 17394802 [PubMed - indexed for MEDLINE]Related articles

Work-independent assessment of efficiency in ex vivo working rodent hearts within the PVA-MVO2 framework.

How OJ, Aasum E, Larsen TS.

Acta Physiol (Oxf). 2007 Jun;190(2):171-5. Epub 2007 Mar 30. No abstract available. PMID: 17394570 [PubMed - indexed for MEDLINE]Related articles

The JAK2 V617F mutation involves B- and T-lymphocyte lineages in a subgroup of patients with Philadelphia-chromosome negative chronic myeloproliferative disorders.

Larsen TS, Christensen JH, Hasselbalch HC, Pallisgaard N.

Br J Haematol. 2007 Mar;136(5):745-51.PMID: 17313377 [PubMed - indexed for MEDLINE]Related articles

Glucose and insulin improve cardiac efficiency and postischemic functional recovery in perfused hearts from type 2 diabetic (db/db) mice.

Hafstad AD, Khalid AM, How OJ, Larsen TS, Aasum E.

Am J Physiol Endocrinol Metab. 2007 May;292(5):E1288-94. Epub 2007 Jan 9.PMID: 17213470 [PubMed - indexed for MEDLINE]Related articlesFree article

A der(18)t(9;18)(p13;p11) and a der(9;18)(p10;q10) in polycythemia vera associated with a hyperproliferative phenotype in transformation to postpolycythemic myelofibrosis.

Larsen TS, Hasselbalch HC, Pallisgaard N, Kerndrup GB.

Cancer Genet Cytogenet. 2007 Jan 15;172(2):107-12.PMID: 17213018 [PubMed - indexed for MEDLINE]Related articles

[New molecular markers within the chronic myeloproliferative disorders. II: the JAK2 mutation]

Larsen TS, Pallisgaard N, Christensen JH, Gram-Hansen P, Kerndrup GB, Møller MB, Hasselbalch HC.

Ugeskr Laeger. 2006 Sep 25;168(39):3299-303. Review. Danish. PMID: 17032592 [PubMed - indexed for MEDLINE]Related articles

[New molecular markers within the chronic myeloproliferative disorders. I: the PRV-1 gene]

Larsen TS, Pallisgaard N, Christensen JH, Gram-Hansen P, Kerndrup GB, Møller MB, Hasselbalch HC.

Ugeskr Laeger. 2006 Sep 25;168(39):3295-9. Review. Danish. PMID: 17032591 [PubMed - indexed for MEDLINE]Related articles

Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation.

Campbell PJ, Baxter EJ, Beer PA, Scott LM, Bench AJ, Huntly BJ, Erber WN, Kusec R, Larsen TS, Giraudier S, Le Bousse-Kerdilès MC, Griesshammer M, Reilly JT, Cheung BY, Harrison CN, Green AR.

Blood. 2006 Nov 15;108(10):3548-55. Epub 2006 Jul 27.PMID: 16873677 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway.

Pellieux C, Aasum E, Larsen TS, Montessuit C, Papageorgiou I, Pedrazzini T, Lerch R.

J Mol Cell Cardiol. 2006 Sep;41(3):459-66. Epub 2006 Jul 21.PMID: 16859699 [PubMed - indexed for MEDLINE]Related articles

[Training in basic laparoscopic technique and implementation of diagnostic laparoscopy]

Larsen TS, Trap R.

Ugeskr Laeger. 2006 Mar 6;168(10):1007-10. Danish. PMID: 16522290 [PubMed - indexed for MEDLINE]Related articles

Reduced coronary reserve in response to short-term ischaemia and vasoactive drugs in ex vivo hearts from diabetic mice.

Bratkovsky SV, Aasum E, Riemersma RA, Myhre ES, Larsen TS.

Acta Physiol (Oxf). 2006 Mar;186(3):171-7.PMID: 16497196 [PubMed - indexed for MEDLINE]Related articles

Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice.

How OJ, Aasum E, Severson DL, Chan WY, Essop MF, Larsen TS.

Diabetes. 2006 Feb;55(2):466-73.PMID: 16443782 [PubMed - indexed for MEDLINE]Related articlesFree article

Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin.

Hafstad AD, Solevåg GH, Severson DL, Larsen TS, Aasum E.

Am J Physiol Heart Circ Physiol. 2006 May;290(5):H1763-9. Epub 2005 Dec 3.PMID: 16327015 [PubMed - indexed for MEDLINE]Related articlesFree article

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis.

Campbell PJ, Griesshammer M, Döhner K, Döhner H, Kusec R, Hasselbalch HC, Larsen TS, Pallisgaard N, Giraudier S, Le Bousse-Kerdilès MC, Desterke C, Guerton B, Dupriez B, Bordessoule D, Fenaux P, Kiladjian JJ, Viallard JF, Brière J, Harrison CN, Green AR, Reilly JT.

Blood. 2006 Mar 1;107(5):2098-100. Epub 2005 Nov 17.PMID: 16293597 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of BM 17.0744, a PPARalpha ligand, on the metabolism of perfused hearts from control and diabetic mice.

Aasum E, Cooper M, Severson DL, Larsen TS.

Can J Physiol Pharmacol. 2005 Feb;83(2):183-90.PMID: 15791292 [PubMed - indexed for MEDLINE]Related articles

Influence of substrate supply on cardiac efficiency, as measured by pressure-volume analysis in ex vivo mouse hearts.

How OJ, Aasum E, Kunnathu S, Severson DL, Myhre ES, Larsen TS.

Am J Physiol Heart Circ Physiol. 2005 Jun;288(6):H2979-85. Epub 2005 Mar 11.PMID: 15764683 [PubMed - indexed for MEDLINE]Related articlesFree article

Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species.

Rey MW, Ramaiya P, Nelson BA, Brody-Karpin SD, Zaretsky EJ, Tang M, Lopez de Leon A, Xiang H, Gusti V, Clausen IG, Olsen PB, Rasmussen MD, Andersen JT, Jørgensen PL, Larsen TS, Sorokin A, Bolotin A, Lapidus A, Galleron N, Ehrlich SD, Berka RM.

Genome Biol. 2004;5(10):R77. Epub 2004 Sep 13.PMID: 15461803 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous glycogen prevents Ca2+ overload and hypercontracture in harp seal myocardial cells during simulated ischemia.

Henden T, Aasum E, Folkow L, Mjøs OD, Lathrop DA, Larsen TS.

J Mol Cell Cardiol. 2004 Jul;37(1):43-50.PMID: 15242734 [PubMed - indexed for MEDLINE]Related articles

Measurement of coronary flow reserve in isolated hearts from mice.

Bratkovsky S, Aasum E, Birkeland CH, Riemersma RA, Myhre ES, Larsen TS.

Acta Physiol Scand. 2004 Jun;181(2):167-72.PMID: 15180788 [PubMed - indexed for MEDLINE]Related articles

Treatment of type 2 diabetic db/db mice with a novel PPARgamma agonist improves cardiac metabolism but not contractile function.

Carley AN, Semeniuk LM, Shimoni Y, Aasum E, Larsen TS, Berger JP, Severson DL.

Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E449-55. Epub 2003 Nov 4.PMID: 14600074 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in substrate metabolism in isolated mouse hearts following ischemia-reperfusion.

Aasum E, Hafstad AD, Larsen TS.

Mol Cell Biochem. 2003 Jul;249(1-2):97-103.PMID: 12956404 [PubMed - indexed for MEDLINE]Related articles

EasyGene--a prokaryotic gene finder that ranks ORFs by statistical significance.

Larsen TS, Krogh A.

BMC Bioinformatics. 2003 Jun 3;4:21. Epub 2003 Jun 3.PMID: 12783628 [PubMed - indexed for MEDLINE]Related articlesFree article

RpoD promoters in Campylobacter jejuni exhibit a strong periodic signal instead of a -35 box.

Petersen L, Larsen TS, Ussery DW, On SL, Krogh A.

J Mol Biol. 2003 Mar 7;326(5):1361-72.PMID: 12595250 [PubMed - indexed for MEDLINE]Related articles

Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice.

Aasum E, Hafstad AD, Severson DL, Larsen TS.

Diabetes. 2003 Feb;52(2):434-41.PMID: 12540618 [PubMed - indexed for MEDLINE]Related articlesFree article

Contaminants in Svalbard polar bear samples archived since 1967 and possible population level effects.

Derocher AE, Wolkers H, Colborn T, Schlabach M, Larsen TS, Wiig Ø.

Sci Total Environ. 2003 Jan 1;301(1-3):163-74.PMID: 12493194 [PubMed - indexed for MEDLINE]Related articles

Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator.

Aasum E, Belke DD, Severson DL, Riemersma RA, Cooper M, Andreassen M, Larsen TS.

Am J Physiol Heart Circ Physiol. 2002 Sep;283(3):H949-57.PMID: 12181123 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac function in perfused hearts from diabetic mice.

Belke DD, Larsen TS, Severson DL.

Adv Exp Med Biol. 2001;498:241-5. No abstract available. PMID: 11900374 [PubMed - indexed for MEDLINE]Related articles

Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.

Parkhill J, Dougan G, James KD, Thomson NR, Pickard D, Wain J, Churcher C, Mungall KL, Bentley SD, Holden MT, Sebaihia M, Baker S, Basham D, Brooks K, Chillingworth T, Connerton P, Cronin A, Davis P, Davies RM, Dowd L, White N, Farrar J, Feltwell T, Hamlin N, Haque A, Hien TT, Holroyd S, Jagels K, Krogh A, Larsen TS, Leather S, Moule S, O'Gaora P, Parry C, Quail M, Rutherford K, Simmonds M, Skelton J, Stevens K, Whitehead S, Barrell BG.

Nature. 2001 Oct 25;413(6858):848-52.PMID: 11677608 [PubMed - indexed for MEDLINE]Related articles

Sigma A recognition sites in the Bacillus subtilis genome.

Jarmer H, Larsen TS, Krogh A, Saxild HH, Brunak S, Knudsen S.

Microbiology. 2001 Sep;147(Pt 9):2417-24.PMID: 11535782 [PubMed - indexed for MEDLINE]Related articlesFree article

Lead and zinc in sediments and biota from Maarmorilik, West Greenland: an assessment of the environmental impact of mining wastes on an Arctic fjord system.

Larsen TS, Kristensen JA, Asmund G, Bjerregaard P.

Environ Pollut. 2001;114(2):275-83.PMID: 11504350 [PubMed - indexed for MEDLINE]Related articles

Glucose-insulin-potassium reduces infarct size when administered during reperfusion.

Jonassen AK, Aasum E, Riemersma RA, Mjøs OD, Larsen TS.

Cardiovasc Drugs Ther. 2000 Dec;14(6):615-23.PMID: 11300362 [PubMed - indexed for MEDLINE]Related articles

Genome organisation and chromatin structure in Escherichia coli.

Ussery D, Larsen TS, Wilkes KT, Friis C, Worning P, Krogh A, Brunak S.

Biochimie. 2001 Feb;83(2):201-12.PMID: 11278070 [PubMed - indexed for MEDLINE]Related articles

Glucose metabolism in perfused mouse hearts overexpressing human GLUT-4 glucose transporter.

Belke DD, Larsen TS, Gibbs EM, Severson DL.

Am J Physiol Endocrinol Metab. 2001 Mar;280(3):E420-7.PMID: 11171596 [PubMed - indexed for MEDLINE]Related articlesFree article