PubMed

The Imprinted Gene Neuronatin Is Regulated by Metabolic Status and Associated With Obesity.

Vrang N, Meyre D, Froguel P, Jelsing J, Tang-Christensen M, Vatin V, Mikkelsen JD, Thirstrup K, Larsen LK, Cullberg KB, Fahrenkrug J, Jacobson P, Sjöström L, Carlsson LM, Liu Y, Liu X, Deng HW, Larsen PJ.

Obesity (Silver Spring). 2009 Oct 22. [Epub ahead of print]PMID: 19851307 [PubMed - as supplied by publisher]Related articles

Characterization of beta-Cell Mass and Insulin Resistance in Diet-induced Obese and Diet-resistant Rats.

Paulsen SJ, Jelsing J, Madsen AN, Hansen G, Lykkegaard K, Larsen LK, Larsen PJ, Levin BE, Vrang N.

Obesity (Silver Spring). 2009 Aug 6. [Epub ahead of print]PMID: 19661956 [PubMed - as supplied by publisher]Related articles

The effect of leptin receptor deficiency and fasting on cannabinoid receptor 1 mRNA expression in the rat hypothalamus, brainstem and nodose ganglion.

Jelsing J, Larsen PJ, Vrang N.

Neurosci Lett. 2009 Oct 2;463(2):125-9. Epub 2009 Jul 9.PMID: 19596404 [PubMed - indexed for MEDLINE]Related articles

Localization and phenotypic characterization of brainstem neurons activated by rimonabant and WIN55,212-2.

Jelsing J, Galzin AM, Guillot E, Pruniaux MP, Larsen PJ, Vrang N.

Brain Res Bull. 2009 Mar 16;78(4-5):202-10. Epub 2008 Nov 25.PMID: 19038314 [PubMed - indexed for MEDLINE]Related articles

Rimonabant induced anorexia in rodents is not mediated by vagal or sympathetic gut afferents.

Madsen AN, Jelsing J, van de Wall EH, Vrang N, Larsen PJ, Schwartz GJ.

Neurosci Lett. 2009 Jan 2;449(1):20-3. Epub 2008 Oct 7.PMID: 18926875 [PubMed - indexed for MEDLINE]Related articles

Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-gamma) agonist balaglitazone.

Larsen PJ, Lykkegaard K, Larsen LK, Fleckner J, Sauerberg P, Wassermann K, Wulff EM.

Eur J Pharmacol. 2008 Oct 31;596(1-3):173-9. Epub 2008 Aug 16.PMID: 18761337 [PubMed - indexed for MEDLINE]Related articles

Higher physical activity is associated with increased androgens, low interleukin 6 and less aortic calcification in peripheral obese elderly women.

Straub RH, Tankó LB, Christiansen C, Larsen PJ, Jessop DS.

J Endocrinol. 2008 Oct;199(1):61-8. Epub 2008 Jul 10.PMID: 18617605 [PubMed - indexed for MEDLINE]Related articlesFree article

The once-daily human GLP-1 analog, liraglutide, reduces olanzapine-induced weight gain and glucose intolerance.

Lykkegaard K, Larsen PJ, Vrang N, Bock C, Bock T, Knudsen LB.

Schizophr Res. 2008 Aug;103(1-3):94-103. Epub 2008 Jun 25.PMID: 18579346 [PubMed - indexed for MEDLINE]Related articles

Identification of cannabinoid type 1 receptor expressing cocaine amphetamine-regulated transcript neurons in the rat hypothalamus and brainstem using in situ hybridization and immunohistochemistry.

Jelsing J, Larsen PJ, Vrang N.

Neuroscience. 2008 Jun 23;154(2):641-52. Epub 2008 Mar 29.PMID: 18472225 [PubMed - indexed for MEDLINE]Related articles

Combination of the insulin sensitizer, pioglitazone, and the long-acting GLP-1 human analog, liraglutide, exerts potent synergistic glucose-lowering efficacy in severely diabetic ZDF rats.

Larsen PJ, Wulff EM, Gotfredsen CF, Brand CL, Sturis J, Vrang N, Knudsen LB, Lykkegaard K.

Diabetes Obes Metab. 2008 Apr;10(4):301-11.PMID: 18333889 [PubMed - indexed for MEDLINE]Related articles

Upregulation of the brainstem preproglucagon system in the obese Zucker rat.

Vrang N, Larsen PJ, Jensen PB, Lykkegaard K, Artmann A, Larsen LK, Tang-Christensen M.

Brain Res. 2008 Jan 2;1187:116-24. Epub 2007 Oct 22.PMID: 18022140 [PubMed - indexed for MEDLINE]Related articles

Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei.

Vrang N, Hansen M, Larsen PJ, Tang-Christensen M.

Brain Res. 2007 May 29;1149:118-26. Epub 2007 Feb 27.PMID: 17433266 [PubMed - indexed for MEDLINE]Related articles

PYY(3-36) reduces food intake and body weight and improves insulin sensitivity in rodent models of diet-induced obesity.

Vrang N, Madsen AN, Tang-Christensen M, Hansen G, Larsen PJ.

Am J Physiol Regul Integr Comp Physiol. 2006 Aug;291(2):R367-75. Epub 2006 Apr 13.PMID: 16914421 [PubMed - indexed for MEDLINE]Related articles

The role of CART in body weight homeostasis.

Larsen PJ, Hunter RG.

Peptides. 2006 Aug;27(8):1981-6. Epub 2006 Jun 9. Review.PMID: 16762453 [PubMed - indexed for MEDLINE]Related articles

Intestinal levels of anandamide and oleoylethanolamide in food-deprived rats are regulated through their precursors.

Petersen G, Sørensen C, Schmid PC, Artmann A, Tang-Christensen M, Hansen SH, Larsen PJ, Schmid HH, Hansen HS.

Biochim Biophys Acta. 2006 Feb;1761(2):143-50; discussion 141-2. Epub 2006 Jan 26.PMID: 16478679 [PubMed - indexed for MEDLINE]Related articles

ACDC/adiponectin and PPAR-gamma gene polymorphisms: implications for features of obesity.

Tankó LB, Siddiq A, Lecoeur C, Larsen PJ, Christiansen C, Walley A, Froguel P.

Obes Res. 2005 Dec;13(12):2113-21.PMID: 16421345 [PubMed - indexed for MEDLINE]Related articles

[Molecular pathogenesis in monogenic and polygenic obesity]

Larsen PJ, Echwald SM, Sørensen TI, Pedersen OB.

Ugeskr Laeger. 2006 Jan 9;168(2):152-5. Danish. PMID: 16403339 [PubMed - indexed for MEDLINE]Related articles

[The genetics of obesity]

Echwald SM, Larsen PJ, Pedersen OB, Sørensen TI.

Ugeskr Laeger. 2006 Jan 9;168(2):150-2. Danish. PMID: 16403338 [PubMed - indexed for MEDLINE]Related articles

[Central fat deposits contribute to atherosclerosis and insulin resistance and peripheral fat deposits protect against atherosclerosis and insulin resistance in postmenopausal women--secondary publication]

Tanko LB, Richelsen B, Larsen PJ.

Ugeskr Laeger. 2005 Sep 19;167(38):3597-601. Danish. PMID: 16219191 [PubMed - indexed for MEDLINE]Related articles

Enlarged waist combined with elevated triglycerides is a strong predictor of accelerated atherogenesis and related cardiovascular mortality in postmenopausal women.

Tankó LB, Bagger YZ, Qin G, Alexandersen P, Larsen PJ, Christiansen C.

Circulation. 2005 Apr 19;111(15):1883-90.PMID: 15837940 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter.

Larsen PJ, Holst JJ.

Regul Pept. 2005 Jun 15;128(2):97-107. Review.PMID: 15780429 [PubMed - indexed for MEDLINE]Related articles

Melanopsin is expressed in PACAP-containing retinal ganglion cells of the human retinohypothalamic tract.

Hannibal J, Hindersson P, Ostergaard J, Georg B, Heegaard S, Larsen PJ, Fahrenkrug J.

Invest Ophthalmol Vis Sci. 2004 Nov;45(11):4202-9.PMID: 15505076 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel associations between bioavailable estradiol and adipokines in elderly women with different phenotypes of obesity: implications for atherogenesis.

Tankó LB, Bruun JM, Alexandersen P, Bagger YZ, Richelsen B, Christiansen C, Larsen PJ.

Circulation. 2004 Oct 12;110(15):2246-52. Epub 2004 Sep 27.PMID: 15451790 [PubMed - indexed for MEDLINE]Related articlesFree article

Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis.

Thorens B, Larsen PJ.

Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):471-8. Review.PMID: 15192452 [PubMed - indexed for MEDLINE]Related articles

Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis.

Larsen PJ, Jensen PB, Sørensen RV, Larsen LK, Vrang N, Wulff EM, Wassermann K.

Diabetes. 2003 Sep;52(9):2249-59.PMID: 12941763 [PubMed - indexed for MEDLINE]Related articlesFree article

Central and peripheral fat mass have contrasting effect on the progression of aortic calcification in postmenopausal women.

Tankó LB, Bagger YZ, Alexandersen P, Larsen PJ, Christiansen C.

Eur Heart J. 2003 Aug;24(16):1531-7.PMID: 12919778 [PubMed - indexed for MEDLINE]Related articlesFree article

Projections from the raphe nuclei to the suprachiasmatic nucleus of the rat.

Hay-Schmidt A, Vrang N, Larsen PJ, Mikkelsen JD.

J Chem Neuroanat. 2003 Jul;25(4):293-310.PMID: 12842274 [PubMed - indexed for MEDLINE]Related articles

Central pre-proglucagon derived peptides: opportunities for treatment of obesity.

Larsen PJ, Vrang N, Tang-Christensen M.

Curr Pharm Des. 2003;9(17):1373-82. Review.PMID: 12769729 [PubMed - indexed for MEDLINE]Related articles

Variations in percentage of body fat within different BMI groups in young, middle-aged and old women.

Movsesyan L, Tankó LB, Larsen PJ, Christiansen C, Svendsen OL.

Clin Physiol Funct Imaging. 2003 May;23(3):130-3.PMID: 12752553 [PubMed - indexed for MEDLINE]Related articles

Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women.

Tankó LB, Bagger YZ, Alexandersen P, Larsen PJ, Christiansen C.

Circulation. 2003 Apr 1;107(12):1626-31. Epub 2003 Mar 17.PMID: 12668497 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic cocaine-amphetamine regulated transcript (CART) is regulated by glucocorticoids.

Vrang N, Larsen PJ, Tang-Christensen M, Larsen LK, Kristensen P.

Brain Res. 2003 Mar 7;965(1-2):45-50.PMID: 12591118 [PubMed - indexed for MEDLINE]Related articles

Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit.

Larsen PJ, Seier V, Fink-Jensen A, Holst JJ, Warberg J, Vrang N.

J Neuroendocrinol. 2003 Mar;15(3):219-26.PMID: 12588509 [PubMed - indexed for MEDLINE]Related articles

PPARalpha /gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly.

Ye JM, Iglesias MA, Watson DG, Ellis B, Wood L, Jensen PB, Sørensen RV, Larsen PJ, Cooney GJ, Wassermann K, Kraegen EW.

Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E531-40.PMID: 12556350 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of leptin on arcuate pro-opiomelanocortin and cocaine-amphetamine-regulated transcript expression are independent of circulating levels of corticosterone.

Vrang N, Kristensen P, Tang-Christensen M, Larsen PJ.

J Neuroendocrinol. 2002 Nov;14(11):880-6.PMID: 12421341 [PubMed - indexed for MEDLINE]Related articles

Cocaine-amphetamine regulated transcript (CART) expression is not regulated by amphetamine.

Vrang N, Larsen PJ, Kristensen P.

Neuroreport. 2002 Jul 2;13(9):1215-8.PMID: 12151772 [PubMed - indexed for MEDLINE]Related articles

Ups and downs for neuropeptides in body weight homeostasis: pharmacological potential of cocaine amphetamine regulated transcript and pre-proglucagon-derived peptides.

Larsen PJ, Vrang N, Tang-Christensen M, Jensen PB, Hay-Schmidt A, Rømer J, Bjerre-Knudsen L, Kristensen P.

Eur J Pharmacol. 2002 Apr 12;440(2-3):159-72. Review.PMID: 12007533 [PubMed - indexed for MEDLINE]Related articles

New therapeutic developments in the regulation of food intake by neuropeptides.

Larsen PJ, Tang-Christensen M, Vrang N.

Ann Endocrinol (Paris). 2002 Apr;63(2 Pt 1):171-5. Review. No abstract available. PMID: 11994683 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide containing pathways in the regulation of feeding behaviour.

Tang-Christensen M, Vrang N, Larsen PJ.

Int J Obes Relat Metab Disord. 2001 Dec;25 Suppl 5:S42-7.PMID: 11840214 [PubMed - indexed for MEDLINE]Related articlesFree article

Light-induced c-Fos expression in suprachiasmatic nuclei neurons targeting the paraventricular nucleus of the hamster hypothalamus: phase dependence and immunochemical identification.

Munch IC, Møller M, Larsen PJ, Vrang N.

J Comp Neurol. 2002 Jan 1;442(1):48-62.PMID: 11754366 [PubMed - indexed for MEDLINE]Related articles

Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats.

Larsen PJ, Fledelius C, Knudsen LB, Tang-Christensen M.

Diabetes. 2001 Nov;50(11):2530-9.PMID: 11679431 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of NPY-induced c-Fos expression in hypothalamic neurones projecting to the dorsal vagal complex and the lower thoracic spinal cord.

Viñuela MC, Larsen PJ.

J Comp Neurol. 2001 Sep 24;438(3):286-99.PMID: 11550173 [PubMed - indexed for MEDLINE]Related articles

Leptin receptor immunoreactivity is present in ascending serotonergic and catecholaminergic neurons of the rat.

Hay-Schmidt A, Helboe L, Larsen PJ.

Neuroendocrinology. 2001 Apr;73(4):215-26.PMID: 11340335 [PubMed - indexed for MEDLINE]Related articles

Insulin and glucose administration stimulates Fos expression in neurones of the paraventricular nucleus that project to autonomic preganglionic structures.

Carrasco M, Portillo F, Larsen PJ, Vallo JJ.

J Neuroendocrinol. 2001 Apr;13(4):339-46.PMID: 11264721 [PubMed - indexed for MEDLINE]Related articles

[Glucagon-like peptide 2, a neurotransmitter with a newly discovered role in the regulation of food ingestion]

Tang-Christensen M, Larsen PJ, Thulesen J, Nielsen JR, Vrang N.

Ugeskr Laeger. 2001 Jan 15;163(3):287-91. Danish. PMID: 11219107 [PubMed - indexed for MEDLINE]Related articles

Chronic intracerebroventricular administration of recombinant CART(42-89) peptide inhibits and causes weight loss in lean and obese Zucker (fa/fa) rats.

Larsen PJ, Vrang N, Petersen PC, Kristensen P.

Obes Res. 2000 Nov;8(8):590-6.PMID: 11156435 [PubMed - indexed for MEDLINE]Related articles

[Are PPAR-gamma-agonists a secure choice in treatment of overweight diabetic patients?]

Larsen PJ.

Ugeskr Laeger. 2000 Aug 7;162(32):4280-1. Danish. No abstract available. PMID: 10962950 [PubMed - indexed for MEDLINE]Related articles

Central Y4 receptor distribution. Radioactive ribonucleotide probe in situ hybridization with in vitro receptor autoradiography.

Larsen PJ, Kristensen P.

Methods Mol Biol. 2000;153:185-98. No abstract available. PMID: 10957993 [PubMed - indexed for MEDLINE]Related articles

Substance P is involved in terminating the hypothalamo- pituitary-adrenal axis response to acute stress through centrally located neurokinin-1 receptors.

Jessop DS, Renshaw D, Larsen PJ, Chowdrey HS, Harbuz MS.

Stress. 2000 May;3(3):209-20.PMID: 10938582 [PubMed - indexed for MEDLINE]Related articles

The proglucagon-derived peptide, glucagon-like peptide-2, is a neurotransmitter involved in the regulation of food intake.

Tang-Christensen M, Larsen PJ, Thulesen J, Rømer J, Vrang N.

Nat Med. 2000 Jul;6(7):802-7.PMID: 10888930 [PubMed - indexed for MEDLINE]Related articles

Central administration of cocaine-amphetamine-regulated transcript activates hypothalamic neuroendocrine neurons in the rat.

Vrang N, Larsen PJ, Kristensen P, Tang-Christensen M.

Endocrinology. 2000 Feb;141(2):794-801.PMID: 10650962 [PubMed - indexed for MEDLINE]Related articlesFree article