PubMed

Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:Fad oxidoreductase (TftC) of Burkholderia cepacia AC1100.

Webb BN, Ballinger JW, Kim E, Belchik SM, Lam KS, Youn B, Nissen MS, Xun L, Kang C.

J Biol Chem. 2009 Nov 13. [Epub ahead of print]PMID: 19915006 [PubMed - as supplied by publisher]Related articlesFree article

Performance of Children with Autism Spectrum Disorders on the Dimension-Change Card Sort Task.

Dichter GS, Radonovich KJ, Turner-Brown LM, Lam KS, Holtzclaw TN, Bodfish JW.

J Autism Dev Disord. 2009 Nov 5. [Epub ahead of print]PMID: 19890707 [PubMed - as supplied by publisher]Related articles

Structure -activity relationship studies of targeting ligands against breast cancer cells.

Yao N, Xiao W, Meza L, Tseng H, Chuck M, Lam KS.

J Med Chem. 2009 Nov 12;52(21):6744-51.PMID: 19835381 [PubMed - in process]Related articles

Prophylactic thyroidectomy in ethnic Chinese patients with multiple endocrine neoplasia type 2A syndrome after the introduction of genetic testing.

Lau GS, Lang BH, Lo CY, Tso A, Garcia-Barcelo MM, Tam PK, Lam KS.

Hong Kong Med J. 2009 Oct;15(5):326-31.PMID: 19801688 [PubMed - in process]Related articlesFree article

A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer.

Xiao K, Luo J, Fowler WL, Li Y, Lee JS, Xing L, Cheng RH, Wang L, Lam KS.

Biomaterials. 2009 Oct;30(30):6006-16. Epub 2009 Aug 5.PMID: 19660809 [PubMed - in process]Related articles

Rapid and sustained reduction of serum growth hormone and insulin-like growth factor-1 in patients with acromegaly receiving lanreotide Autogel((R)) therapy: a randomized, placebo-controlled, multicenter study with a 52 week open extension.

Melmed S, Cook D, Schopohl J, Goth MI, Lam KS, Marek J.

Pituitary. 2009 Jul 29. [Epub ahead of print]PMID: 19639415 [PubMed - as supplied by publisher]Related articles

A randomized controlled trial of nCPAP on insulin sensitivity in obstructive sleep apnoea.

Lam JC, Lam B, Yao TJ, Lai AY, Ooi CG, Tam S, Lam KS, Ip MS.

Eur Respir J. 2009 Jul 16. [Epub ahead of print]PMID: 19608589 [PubMed - as supplied by publisher]Related articles

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling.

Saegusa J, Yamaji S, Ieguchi K, Wu CY, Lam KS, Liu FT, Takada YK, Takada Y.

J Biol Chem. 2009 Sep 4;284(36):24106-14. Epub 2009 Jul 3.PMID: 19578119 [PubMed - indexed for MEDLINE]Related articles

Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support.

Sun YS, Landry JP, Fei YY, Zhu XD, Luo JT, Wang XB, Lam KS.

Anal Chem. 2009 Jul 1;81(13):5373-80.PMID: 19563213 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycaemic control and cardiovascular risk in diabetes: lessons from recent trials.

Lam KS.

Hong Kong Med J. 2009 Jun;15(3):164-5. No abstract available. PMID: 19494368 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocyte fatty acid binding protein levels relate to inflammation and fibrosis in nonalcoholic fatty liver disease.

Milner KL, van der Poorten D, Xu A, Bugianesi E, Kench JG, Lam KS, Chisholm DJ, George J.

Hepatology. 2009 Jun;49(6):1926-34.PMID: 19475694 [PubMed - indexed for MEDLINE]Related articles

Protective roles of adiponectin in obesity-related fatty liver diseases: mechanisms and therapeutic implications.

Wang Y, Zhou M, Lam KS, Xu A.

Arq Bras Endocrinol Metabol. 2009 Mar;53(2):201-12.PMID: 19466213 [PubMed - in process]Related articlesFree article

APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice.

Cheng KK, Iglesias MA, Lam KS, Wang Y, Sweeney G, Zhu W, Vanhoutte PM, Kraegen EW, Xu A.

Cell Metab. 2009 May;9(5):417-27.PMID: 19416712 [PubMed - indexed for MEDLINE]Related articles

Application of the "libraries from libraries" concept to "one-bead one-compound" combinatorial chemistry.

Kappel JC, Fan YC, Lam KS.

Adv Exp Med Biol. 2009;611:21-2. No abstract available. PMID: 19400077 [PubMed - indexed for MEDLINE]Related articles

A novel hydrogel functionalized with specific peptidomimetic ligands for 2-D and 3-D cell culture.

Luo J, Onofiok E, Shi C, Liu R, Lam KS.

Adv Exp Med Biol. 2009;611:19-20. No abstract available. PMID: 19400076 [PubMed - indexed for MEDLINE]Related articles

Generativity abilities predict communication deficits but not repetitive behaviors in Autism Spectrum Disorders.

Dichter GS, Lam KS, Turner-Brown LM, Holtzclaw TN, Bodfish JW.

J Autism Dev Disord. 2009 Sep;39(9):1298-304. Epub 2009 Apr 25.PMID: 19396536 [PubMed - indexed for MEDLINE]Related articles

On-demand cleavable linkers for radioimmunotherapy.

Kumaresan PR, Luo J, Lam KS.

Methods Mol Biol. 2009;539:191-211.PMID: 19377973 [PubMed - indexed for MEDLINE]Related articles

Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006.

Cheung BM, Ong KL, Cherny SS, Sham PC, Tso AW, Lam KS.

Am J Med. 2009 May;122(5):443-53.PMID: 19375554 [PubMed - indexed for MEDLINE]Related articles

Serum zinc-alpha2-glycoprotein correlates with adiposity, triglycerides, and the key components of the metabolic syndrome in Chinese subjects.

Yeung DC, Lam KS, Wang Y, Tso AW, Xu A.

J Clin Endocrinol Metab. 2009 Jul;94(7):2531-6. Epub 2009 Apr 7.PMID: 19351730 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.

Law IK, Liu L, Xu A, Lam KS, Vanhoutte PM, Che CM, Leung PT, Wang Y.

Proteomics. 2009 May;9(9):2444-56.PMID: 19343720 [PubMed - indexed for MEDLINE]Related articles

Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice.

Hui X, Zhu W, Wang Y, Lam KS, Zhang J, Wu D, Kraegen EW, Li Y, Xu A.

J Biol Chem. 2009 May 22;284(21):14050-7. Epub 2009 Mar 31.PMID: 19336396 [PubMed - indexed for MEDLINE]Related articles

Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities.

Lam JB, Chow KH, Xu A, Lam KS, Liu J, Wong NS, Moon RT, Shepherd PR, Cooper GJ, Wang Y.

PLoS One. 2009;4(3):e4968. Epub 2009 Mar 25. Erratum in: PLoS One. 2009;4(4). doi: 10.1371/annotation/14cb7d7e-a921-4ae6-a405-99c60656579f. PMID: 19319191 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of Solanum tuberosum multicystatin and its structural comparison with other cystatins.

Nissen MS, Kumar GN, Youn B, Knowles DB, Lam KS, Ballinger WJ, Knowles NR, Kang C.

Plant Cell. 2009 Mar;21(3):861-75. Epub 2009 Mar 20.PMID: 19304935 [PubMed - indexed for MEDLINE]Related articlesFree article

111In-LLP2A-DOTA Polyethylene Glycol-Targeting {alpha}4{beta}1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Lymphoid Malignancies.

Denardo SJ, Liu R, Albrecht H, Natarajan A, Sutcliffe JL, Anderson C, Peng L, Ferdani R, Cherry SR, Lam KS.

J Nucl Med. 2009 Apr;50(4):625-34. Epub 2009 Mar 16.PMID: 19289419 [PubMed - indexed for MEDLINE]Related articles

Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase.

Wang Y, Huang Y, Lam KS, Li Y, Wong WT, Ye H, Lau CW, Vanhoutte PM, Xu A.

Cardiovasc Res. 2009 Jun 1;82(3):484-92. Epub 2009 Feb 27.PMID: 19251722 [PubMed - indexed for MEDLINE]Related articles

A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization.

Yau MH, Wang Y, Lam KS, Zhang J, Wu D, Xu A.

J Biol Chem. 2009 May 1;284(18):11942-52. Epub 2009 Feb 26.PMID: 19246456 [PubMed - indexed for MEDLINE]Related articles

Late-life body mass index and waist circumference in amnestic mild cognitive impairment and Alzheimer's disease.

Chu LW, Tam S, Lee PW, Yik PY, Song Y, Cheung BM, Lam KS.

J Alzheimers Dis. 2009 May;17(1):223-32.PMID: 19221407 [PubMed - indexed for MEDLINE]Related articles

Elevated plasma level of soluble F11 receptor/junctional adhesion molecule-A (F11R/JAM-A) in hypertension.

Ong KL, Leung RY, Babinska A, Salifu MO, Ehrlich YH, Kornecki E, Wong LY, Tso AW, Cherny SS, Sham PC, Lam TH, Lam KS, Cheung BM.

Am J Hypertens. 2009 May;22(5):500-5. Epub 2009 Feb 12.PMID: 19214165 [PubMed - indexed for MEDLINE]Related articles

Serum adipocyte-fatty acid binding protein level is elevated in severe OSA and correlates with insulin resistance.

Lam DC, Xu A, Lam KS, Lam B, Lam JC, Lui MM, Ip MS.

Eur Respir J. 2009 Feb;33(2):346-51.PMID: 19181913 [PubMed - indexed for MEDLINE]Related articles

Adiponectin isoform distribution in women--relationship to female sex steroids and insulin sensitivity.

Leung KC, Xu A, Craig ME, Martin A, Lam KS, O'Sullivan AJ.

Metabolism. 2009 Feb;58(2):239-45.PMID: 19154958 [PubMed - indexed for MEDLINE]Related articles

Antiprotealide Is a Natural Product.

Manam RR, Macherla VR, Tsueng G, Dring CW, Weiss J, Neuteboom ST, Lam KS, Potts BC.

J Nat Prod. 2009 Jan 9. [Epub ahead of print]PMID: 19133779 [PubMed - as supplied by publisher]Related articles

A novel small molecule, LAS-0811, inhibits alcohol-induced apoptosis in VL-17A cells.

Kim TH, Venugopal SK, Zhu M, Wang SS, Lau D, Lam KS, Clemens DL, Zern MA.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):876-81. Epub 2009 Jan 6.PMID: 19133235 [PubMed - indexed for MEDLINE]Related articles

Glycomic approach for potential biomarkers on prostate cancer: profiling of N-linked glycans in human sera and pRNS cell lines.

de Leoz ML, An HJ, Kronewitter S, Kim J, Beecroft S, Vinall R, Miyamoto S, de Vere White R, Lam KS, Lebrilla C.

Dis Markers. 2008;25(4-5):243-58.PMID: 19126968 [PubMed - indexed for MEDLINE]Related articles

Economic cost of osteoporotic hip fractures in Singapore.

Lee YH, Lim YW, Lam KS.

Singapore Med J. 2008 Dec;49(12):980-4.PMID: 19122947 [PubMed - indexed for MEDLINE]Related articlesFree article

An alpha4beta1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice.

Kenyon NJ, Liu R, O'Roark EM, Huang W, Peng L, Lam KS.

Eur J Pharmacol. 2009 Jan 28;603(1-3):138-46. Epub 2008 Dec 13.PMID: 19103195 [PubMed - indexed for MEDLINE]Related articles

Hypoadiponectinemia is related to sympathetic activation and severity of obstructive sleep apnea.

Lam JC, Xu A, Tam S, Khong PI, Yao TJ, Lam DC, Lai AY, Lam B, Lam KS, Mary SM.

Sleep. 2008 Dec 1;31(12):1721-7.PMID: 19090328 [PubMed - indexed for MEDLINE]Related articlesFree article

Selectively targeting T- and B-cell lymphomas: a benzothiazole antagonist of alpha4beta1 integrin.

Carpenter RD, Andrei M, Aina OH, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ.

J Med Chem. 2009 Jan 8;52(1):14-9.PMID: 19072684 [PubMed - indexed for MEDLINE]Related articles

Development of hydrogel TentaGel shell-core beads for ultrahigh throughput solution-phase screening of encoded OBOC combinatorial small molecule libraries.

Baek HG, Liu R, Lam KS.

J Comb Chem. 2009 Jan-Feb;11(1):91-102.PMID: 19061339 [PubMed - indexed for MEDLINE]Related articles

Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method.

Yao N, Xiao W, Wang X, Marik J, Park SH, Takada Y, Lam KS.

J Med Chem. 2009 Jan 8;52(1):126-33.PMID: 19055415 [PubMed - indexed for MEDLINE]Related articles

Discovery and development of the anticancer agent salinosporamide A (NPI-0052).

Fenical W, Jensen PR, Palladino MA, Lam KS, Lloyd GK, Potts BC.

Bioorg Med Chem. 2009 Mar 15;17(6):2175-80. Epub 2008 Nov 5.PMID: 19022674 [PubMed - indexed for MEDLINE]Related articles

Candidate anti-Abeta fluorene compounds selected from analogs of amyloid imaging agents.

Hong HS, Maezawa I, Budamagunta M, Rana S, Shi A, Vassar R, Liu R, Lam KS, Cheng RH, Hua DH, Voss JC, Jin LW.

Neurobiol Aging. 2008 Nov 18. [Epub ahead of print]PMID: 19022536 [PubMed - as supplied by publisher]Related articles

Evidence for three subtypes of repetitive behavior in autism that differ in familiality and association with other symptoms.

Lam KS, Bodfish JW, Piven J.

J Child Psychol Psychiatry. 2008 Nov;49(11):1193-200.PMID: 19017031 [PubMed - indexed for MEDLINE]Related articles

A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization.

Liu M, Zhou L, Xu A, Lam KS, Wetzel MD, Xiang R, Zhang J, Xin X, Dong LQ, Liu F.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18302-7. Epub 2008 Nov 14.PMID: 19011089 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions.

Sun YS, Landry JP, Fei YY, Zhu XD, Luo JT, Wang XB, Lam KS.

Langmuir. 2008 Dec 2;24(23):13399-405.PMID: 18991423 [PubMed - indexed for MEDLINE]Related articlesFree article

High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers.

Park SH, Wang X, Liu R, Lam KS, Weiss RH.

Cancer Biol Ther. 2008 Dec;7(12):2015-22. Epub 2008 Dec 26.PMID: 18981726 [PubMed - indexed for MEDLINE]Related articles

Circulating levels of adipocyte and epidermal fatty acid-binding proteins in relation to nephropathy staging and macrovascular complications in type 2 diabetic patients.

Yeung DC, Xu A, Tso AW, Chow WS, Wat NM, Fong CH, Tam S, Sham PC, Lam KS.

Diabetes Care. 2009 Jan;32(1):132-4. Epub 2008 Oct 17.PMID: 18931100 [PubMed - in process]Related articlesFree article

Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice.

Xu A, Wang H, Hoo RL, Sweeney G, Vanhoutte PM, Wang Y, Wu D, Chu W, Qin G, Lam KS.

Endocrinology. 2009 Feb;150(2):625-33. Epub 2008 Oct 16.PMID: 18927219 [PubMed - indexed for MEDLINE]Related articles

Lynamicins A-E, chlorinated bisindole pyrrole antibiotics from a novel marine actinomycete.

McArthur KA, Mitchell SS, Tsueng G, Rheingold A, White DJ, Grodberg J, Lam KS, Potts BC.

J Nat Prod. 2008 Oct;71(10):1732-7. Epub 2008 Oct 9.PMID: 18842058 [PubMed - indexed for MEDLINE]Related articles

Demographics and clinical presentation of slipped capital femoral epiphysis in Singapore: comparing the East with the West.

Lim YJ, Kagda F, Lam KS, Hui JH, Lim KB, Mahadev A, Lee EH.

J Pediatr Orthop B. 2008 Nov;17(6):289-92.PMID: 18841061 [PubMed - indexed for MEDLINE]Related articles

MRI follow-up of subchondral signal abnormalities in a selected group of chronic low back pain patients.

Lam KS.

Eur Spine J. 2008 Oct;17(10):1309-10. Epub 2008 Sep 16. No abstract available. PMID: 18795340 [PubMed - indexed for MEDLINE]Related articlesFree article