PubMed

Determinants of cardiorespiratory fitness in men aged 42 to 60 years with and without cardiovascular disease.

Laukkanen JA, Laaksonen D, Lakka TA, Savonen K, Rauramaa R, Mäkikallio T, Kurl S.

Am J Cardiol. 2009 Jun 1;103(11):1598-604. Epub 2009 Apr 22.PMID: 19463522 [PubMed - indexed for MEDLINE]Related articles

BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study.

Komulainen P, Pedersen M, Hänninen T, Bruunsgaard H, Lakka TA, Kivipelto M, Hassinen M, Rauramaa TH, Pedersen BK, Rauramaa R.

Neurobiol Learn Mem. 2008 Nov;90(4):596-603. Epub 2008 Sep 6.PMID: 18707012 [PubMed - indexed for MEDLINE]Related articles

Chronotropic incompetence and mortality in middle-aged men with known or suspected coronary heart disease.

Savonen KP, Kiviniemi V, Laukkanen JA, Lakka TA, Rauramaa TH, Salonen JT, Rauramaa R.

Eur Heart J. 2008 Aug;29(15):1896-902. Epub 2008 Jun 13.PMID: 18556711 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of age and education with different types of leisure-time physical activity among 4437 Finnish adults.

Borodulin K, Laatikainen T, Lahti-Koski M, Jousilahti P, Lakka TA.

J Phys Act Health. 2008 Mar;5(2):242-51.PMID: 18382033 [PubMed - indexed for MEDLINE]Related articles

Lifestyle management in the metabolic syndrome.

Hu G, Lakka TA, Lakka HM, Tuomilehto J.

Metab Syndr Relat Disord. 2006 Winter;4(4):270-86.PMID: 18370746 [PubMed - in process]Related articles

Physical activity, physical fitness, and risk of type 2 diabetes mellitus.

Hu G, Lakka TA, Barengo NC, Tuomilehto J.

Metab Syndr Relat Disord. 2005;3(1):35-44.PMID: 18370708 [PubMed - in process]Related articles

Usefulness of chronotropic incompetence in response to exercise as a predictor of myocardial infarction in middle-aged men without cardiovascular disease.

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R.

Am J Cardiol. 2008 Apr 1;101(7):992-8. Epub 2008 Jan 28.PMID: 18359320 [PubMed - indexed for MEDLINE]Related articles

Cardiorespiratory fitness as a feature of metabolic syndrome in older men and women: the Dose-Responses to Exercise Training study (DR's EXTRA).

Hassinen M, Lakka TA, Savonen K, Litmanen H, Kiviaho L, Laaksonen DE, Komulainen P, Rauramaa R.

Diabetes Care. 2008 Jun;31(6):1242-7. Epub 2008 Mar 10.PMID: 18332159 [PubMed - indexed for MEDLINE]Related articlesFree article

Dyslipidaemia as a predictor of hypertension in middle-aged men.

Laaksonen DE, Niskanen L, Nyyssönen K, Lakka TA, Laukkanen JA, Salonen JT.

Eur Heart J. 2008 Oct;29(20):2561-8. Epub 2008 Feb 28.PMID: 18308688 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study.

Kilpeläinen TO, Lakka TA, Laaksonen DE, Mager U, Salopuro T, Kubaszek A, Todorova B, Laukkanen O, Lindström J, Eriksson JG, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M; Finnish Diabetes Prevention Study Group.

Metabolism. 2008 Mar;57(3):428-36.PMID: 18249219 [PubMed - indexed for MEDLINE]Related articles

SNPs in PPARG associate with type 2 diabetes and interact with physical activity.

Kilpeläinen TO, Lakka TA, Laaksonen DE, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Lindi V, Tuomilehto J, Uusitupa M, Laakso M.

Med Sci Sports Exerc. 2008 Jan;40(1):25-33.PMID: 18091023 [PubMed - indexed for MEDLINE]Related articles

Physical activity and diabetes complications in patients with type 1 diabetes: the Finnish Diabetic Nephropathy (FinnDiane) Study.

Wadén J, Forsblom C, Thorn LM, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Lakka TA, Tikkanen H, Groop PH; FinnDiane Study Group.

Diabetes Care. 2008 Feb;31(2):230-2. Epub 2007 Oct 24. No abstract available. PMID: 17959867 [PubMed - indexed for MEDLINE]Related articlesFree article

Workload at the heart rate of 100 beats/min and mortality in middle-aged men with known or suspected coronary heart disease.

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R.

Heart. 2008 Apr;94(4):e14. Epub 2007 Oct 4.PMID: 17916660 [PubMed - indexed for MEDLINE]Related articles

Carotid intima-media thickness and cognitive function in elderly women: a population-based study.

Komulainen P, Kivipelto M, Lakka TA, Hassinen M, Helkala EL, Patja K, Nissinen A, Rauramaa R.

Neuroepidemiology. 2007;28(4):207-13. Epub 2007 Sep 11.PMID: 17851259 [PubMed - indexed for MEDLINE]Related articles

Effectiveness of workload at the heart rate of 100 beats/min in predicting cardiovascular mortality in men aged 42, 48, 54, or 60 years at baseline.

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R.

Am J Cardiol. 2007 Aug 15;100(4):563-8. Epub 2007 Jun 28.PMID: 17697806 [PubMed - indexed for MEDLINE]Related articles

Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes.

Kilpeläinen TO, Lakka TA, Laaksonen DE, Laukkanen O, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M; Finnish Diabetes Prevention Study Group.

Physiol Genomics. 2007 Oct 22;31(2):264-72. Epub 2007 Jul 17. Erratum in: Physiol Genomics. 2008 Feb 19;32(3):419. PMID: 17636114 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum high sensitivity C-reactive protein and cognitive function in elderly women.

Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Penttilä IM, Helkala EL, Gylling H, Nissinen A, Rauramaa R.

Age Ageing. 2007 Jul;36(4):443-8. Epub 2007 May 30.PMID: 17537742 [PubMed - indexed for MEDLINE]Related articlesFree article

Epidemiological studies of exercise in diabetes prevention.

Hu G, Lakka TA, Kilpeläinen TO, Tuomilehto J.

Appl Physiol Nutr Metab. 2007 Jun;32(3):583-95. Review.PMID: 17510700 [PubMed - indexed for MEDLINE]Related articles

Association of waist and hip circumference with 12-year progression of carotid intima-media thickness in elderly women.

Hassinen M, Lakka TA, Komulainen P, Haapala I, Nissinen A, Rauramaa R.

Int J Obes (Lond). 2007 Sep;31(9):1406-11. Epub 2007 Mar 20.PMID: 17372615 [PubMed - indexed for MEDLINE]Related articles

Physical activity in prevention and treatment of the metabolic syndrome.

Lakka TA, Laaksonen DE.

Appl Physiol Nutr Metab. 2007 Feb;32(1):76-88. Review.PMID: 17332786 [PubMed - indexed for MEDLINE]Related articles

[Not Available]

Lakka TA.

Duodecim. 2006;122(24):2939-41. Finnish. No abstract available. PMID: 17330418 [PubMed]Related articles

Exercise, genetics and prevention of type 2 diabetes.

Hu G, Rico-Sanz J, Lakka TA, Tuomilehto J.

Essays Biochem. 2006;42:177-92. Review.PMID: 17144888 [PubMed - indexed for MEDLINE]Related articles

Metabolic syndrome and cognitive function: a population-based follow-up study in elderly women.

Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Helkala EL, Haapala I, Nissinen A, Rauramaa R.

Dement Geriatr Cogn Disord. 2007;23(1):29-34. Epub 2006 Oct 27.PMID: 17068394 [PubMed - indexed for MEDLINE]Related articles

Occupational, commuting and leisure-time physical activity in relation to coronary heart disease among middle-aged Finnish men and women.

Hu G, Jousilahti P, Borodulin K, Barengo NC, Lakka TA, Nissinen A, Tuomilehto J.

Atherosclerosis. 2007 Oct;194(2):490-7. Epub 2006 Sep 18.PMID: 16979645 [PubMed - indexed for MEDLINE]Related articles

Systolic blood pressure response to exercise testing is related to the risk of acute myocardial infarction in middle-aged men.

Laukkanen JA, Kurl S, Rauramaa R, Lakka TA, Venäläinen JM, Salonen JT.

Eur J Cardiovasc Prev Rehabil. 2006 Jun;13(3):421-8.PMID: 16926673 [PubMed - indexed for MEDLINE]Related articles

Association of leisure time physical activity and abdominal obesity with fasting serum insulin and 2-h postchallenge plasma glucose levels.

Borodulin K, Tuomilehto J, Peltonen M, Lakka TA, Sundvall J, Jousilahti P.

Diabet Med. 2006 Sep;23(9):1025-8.PMID: 16922711 [PubMed - indexed for MEDLINE]Related articles

Quantitative trait locus on chromosome 20q13 for plasma levels of C-reactive protein in healthy whites: the HERITAGE Family Study.

Lakka TA, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Bouchard C.

Physiol Genomics. 2006 Oct 11;27(2):103-7. Epub 2006 Jul 5.PMID: 16822830 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical activity, obesity and cardiovascular diseases.

Lakka TA, Bouchard C.

Handb Exp Pharmacol. 2005;(170):137-63. Review.PMID: 16596798 [PubMed - indexed for MEDLINE]Related articles

The TNF-alpha G-308A polymorphism is associated with C-reactive protein levels: the HERITAGE Family Study.

Lakka HM, Lakka TA, Rankinen T, Rice T, Rao DC, Leon AS, Skinner JS, Bouchard C.

Vascul Pharmacol. 2006 May;44(5):377-83. Epub 2006 Mar 3.PMID: 16581306 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein and metabolic syndrome in elderly women: a 12-year follow-up study.

Hassinen M, Lakka TA, Komulainen P, Gylling H, Nissinen A, Rauramaa R.

Diabetes Care. 2006 Apr;29(4):931-2. No abstract available. PMID: 16567842 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic syndrome and the progression of carotid intima-media thickness in elderly women.

Hassinen M, Komulainen P, Lakka TA, Väisänen SB, Haapala I, Gylling H, Alen M, Schmidt-Trucksäss A, Nissinen A, Rauramaa R.

Arch Intern Med. 2006 Feb 27;166(4):444-9.PMID: 16505265 [PubMed - indexed for MEDLINE]Related articlesFree article

High dietary methionine intake increases the risk of acute coronary events in middle-aged men.

Virtanen JK, Voutilainen S, Rissanen TH, Happonen P, Mursu J, Laukkanen JA, Poulsen H, Lakka TA, Salonen JT.

Nutr Metab Cardiovasc Dis. 2006 Mar;16(2):113-20. Epub 2005 Nov 2.PMID: 16487911 [PubMed - indexed for MEDLINE]Related articles

Peak oxygen pulse during exercise as a predictor for coronary heart disease and all cause death.

Laukkanen JA, Kurl S, Salonen JT, Lakka TA, Rauramaa R.

Heart. 2006 Sep;92(9):1219-24. Epub 2006 Feb 8.PMID: 16467459 [PubMed - indexed for MEDLINE]Related articlesFree article

Heart rate response during exercise test and cardiovascular mortality in middle-aged men.

Savonen KP, Lakka TA, Laukkanen JA, Halonen PM, Rauramaa TH, Salonen JT, Rauramaa R.

Eur Heart J. 2006 Mar;27(5):582-8. Epub 2006 Jan 6.PMID: 16399774 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study.

Lakka TA, Lakka HM, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C.

Eur Heart J. 2005 Oct;26(19):2018-25. Epub 2005 Jun 29.PMID: 15987707 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical activity, cardiovascular risk factors, and mortality among Finnish adults with diabetes.

Hu G, Jousilahti P, Barengo NC, Qiao Q, Lakka TA, Tuomilehto J.

Diabetes Care. 2005 Apr;28(4):799-805.PMID: 15793176 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations between estimated aerobic fitness and cardiovascular risk factors in adults with different levels of abdominal obesity.

Borodulin K, Laatikainen T, Lahti-Koski M, Lakka TA, Laukkanen R, Sarna S, Jousilahti P.

Eur J Cardiovasc Prev Rehabil. 2005 Apr;12(2):126-31.PMID: 15785297 [PubMed - indexed for MEDLINE]Related articles

Low physical activity as a predictor for antihypertensive drug treatment in 25-64-year-old populations in eastern and south-western Finland.

Barengo NC, Hu G, Kastarinen M, Lakka TA, Pekkarinen H, Nissinen A, Tuomilehto J.

J Hypertens. 2005 Feb;23(2):293-9.PMID: 15662217 [PubMed - indexed for MEDLINE]Related articles

Effects of exercise training on glucose homeostasis: the HERITAGE Family Study.

Boulé NG, Weisnagel SJ, Lakka TA, Tremblay A, Bergman RN, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C; HERITAGE Family Study.

Diabetes Care. 2005 Jan;28(1):108-14.PMID: 15616242 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study.

Laaksonen DE, Lindström J, Lakka TA, Eriksson JG, Niskanen L, Wikström K, Aunola S, Keinänen-Kiukaanniemi S, Laakso M, Valle TT, Ilanne-Parikka P, Louheranta A, Hämäläinen H, Rastas M, Salminen V, Cepaitis Z, Hakumäki M, Kaikkonen H, Härkönen P, Sundvall J, Tuomilehto J, Uusitupa M; Finnish diabetes prevention study.

Diabetes. 2005 Jan;54(1):158-65.PMID: 15616024 [PubMed - indexed for MEDLINE]Related articlesFree article

Depression and early retirement: prospective population based study in middle aged men.

Karpansalo M, Kauhanen J, Lakka TA, Manninen P, Kaplan GA, Salonen JT.

J Epidemiol Community Health. 2005 Jan;59(1):70-4.PMID: 15598730 [PubMed - indexed for MEDLINE]Related articlesFree article

Low physical activity as a predictor for total and cardiovascular disease mortality in middle-aged men and women in Finland.

Barengo NC, Hu G, Lakka TA, Pekkarinen H, Nissinen A, Tuomilehto J.

Eur Heart J. 2004 Dec;25(24):2204-11.PMID: 15589637 [PubMed - indexed for MEDLINE]Related articlesFree article

Systolic blood pressure during recovery from exercise and the risk of acute myocardial infarction in middle-aged men.

Laukkanen JA, Kurl S, Salonen R, Lakka TA, Rauramaa R, Salonen JT.

Hypertension. 2004 Dec;44(6):820-5. Epub 2004 Nov 8.PMID: 15534077 [PubMed - indexed for MEDLINE]Related articlesFree article

Epidemiology and treatment of the metabolic syndrome.

Laaksonen DE, Niskanen L, Lakka HM, Lakka TA, Uusitupa M.

Ann Med. 2004;36(5):332-46. Review.PMID: 15478308 [PubMed - indexed for MEDLINE]Related articles

Perceived health as a predictor of early retirement.

Karpansalo M, Manninen P, Kauhanen J, Lakka TA, Salonen JT.

Scand J Work Environ Health. 2004 Aug;30(4):287-92.PMID: 15458011 [PubMed - indexed for MEDLINE]Related articles

Occupational, commuting, and leisure-time physical activity in relation to total and cardiovascular mortality among Finnish subjects with type 2 diabetes.

Hu G, Eriksson J, Barengo NC, Lakka TA, Valle TT, Nissinen A, Jousilahti P, Tuomilehto J.

Circulation. 2004 Aug 10;110(6):666-73. Epub 2004 Jul 26.PMID: 15277321 [PubMed - indexed for MEDLINE]Related articlesFree article

Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study.

Niskanen LK, Laaksonen DE, Nyyssönen K, Alfthan G, Lakka HM, Lakka TA, Salonen JT.

Arch Intern Med. 2004 Jul 26;164(14):1546-51.PMID: 15277287 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO Study: a six-year randomized, controlled trial.

Rauramaa R, Halonen P, Väisänen SB, Lakka TA, Schmidt-Trucksäss A, Berg A, Penttilä IM, Rankinen T, Bouchard C.

Ann Intern Med. 2004 Jun 15;140(12):1007-14.PMID: 15197018 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin and leptin receptor gene polymorphisms and changes in glucose homeostasis in response to regular exercise in nondiabetic individuals: the HERITAGE family study.

Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Lakka HM, Ukkola O, Boulé N, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Bouchard C.

Diabetes. 2004 Jun;53(6):1603-8.PMID: 15161768 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic lipase C-480T polymorphism modifies the effect of HDL cholesterol on the risk of acute myocardial infarction in men: a prospective population based study.

Fan YM, Salonen JT, Koivu TA, Tuomainen TP, Nyyssönen K, Lakka TA, Salonen R, Seppänen K, Nikkari ST, Tahvanainen E, Lehtimäki T.

J Med Genet. 2004 Mar;41(3):e28. No abstract available. PMID: 14985399 [PubMed - indexed for MEDLINE]Related articlesFree article