PubMed

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function.

Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H, Becker DJ, Gitelman SE, Goland R, Gottlieb PA, Marks JB, McGee PF, Moran AM, Raskin P, Rodriguez H, Schatz DA, Wherrett D, Wilson DM, Lachin JM, Skyler JS; the Type 1 Diabetes TrialNet Anti-CD20 Study Group.

N Engl J Med. 2009 Nov 26;361(22):2143-2152.PMID: 19940299 [PubMed - as supplied by publisher]

Futility interim monitoring with control of type I and II error probabilities using the interim Z-value or confidence limit.

Lachin JM.

Clin Trials. 2009 Nov 23. [Epub ahead of print]PMID: 19933716 [PubMed - as supplied by publisher]

A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both HbA1c and glucose.

Paterson AD, Waggott D, Boright AP, Hosseini SM, Shen E, Sylvestre MP, Wong I, Bharaj B, Cleary PA, Lachin JM; MAGIC, Below JE, Nicolae D, Cox NJ, Canty AJ, Sun L, Bull SB; The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group.

Diabetes. 2009 Oct 29. [Epub ahead of print]PMID: 19875614 [PubMed - as supplied by publisher]Related articles

Effect of Rosiglitazone, Metformin, and Glyburide on Bone Biomarkers in Patients with Type 2 Diabetes.

Zinman B, Haffner SM, Herman WH, Holman RR, Lachin JM, Kravitz BG, Paul G, Jones NP, Aftring RP, Viberti G, Kahn SE; the A Diabetes Outcome Progression Trial Study Group.

J Clin Endocrinol Metab. 2009 Oct 29. [Epub ahead of print]PMID: 19875477 [PubMed - as supplied by publisher]Related articles

Rosiglitazone Decreases C-Reactive Protein to a Greater Extent Relative to Glyburide and Metformin over Four-Years in Spite of Greater Weight Gain: Observations from ADOPT (A Diabetes Outcome Progression Trial).

Kahn SE, Haffner SM, Viberti G, Herman WH, Lachin JM, Kravitz BG, Yu D, Paul G, Holman RR, Zinman B; for the ADOPT Study Group.

Diabetes Care. 2009 Oct 16. [Epub ahead of print]PMID: 19808911 [PubMed - as supplied by publisher]Related articles

Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes.

Herold KC, Brooks-Worrell B, Palmer J, Dosch HM, Peakman M, Gottlieb P, Reijonen H, Arif S, Spain LM, Thompson C, Lachin JM; Type 1 Diabetes TrialNet Research Group.

Diabetes. 2009 Nov;58(11):2588-95. Epub 2009 Aug 12.PMID: 19675135 [PubMed - in process]Related articles

Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC).

Pop-Busui R, Low PA, Waberski BH, Martin CL, Albers JW, Feldman EL, Sommer C, Cleary PA, Lachin JM, Herman WH; DCCT/EDIC Research Group.

Circulation. 2009 Jun 9;119(22):2886-93. Epub 2009 May 26.PMID: 19470886 [PubMed - in process]Related articles

Type 1 Diabetes TrialNet--an international collaborative clinical trials network.

Skyler JS, Greenbaum CJ, Lachin JM, Leschek E, Rafkin-Mervis L, Savage P, Spain L; Type 1 Diabetes TrialNet Study Group.

Ann N Y Acad Sci. 2008 Dec;1150:14-24.PMID: 19120262 [PubMed - indexed for MEDLINE]Related articles

Association of diet with glycated hemoglobin during intensive treatment of type 1 diabetes in the Diabetes Control and Complications Trial.

Delahanty LM, Nathan DM, Lachin JM, Hu FB, Cleary PA, Ziegler GK, Wylie-Rosett J, Wexler DJ; Diabetes Control and Complications Trial/Epidemiology of Diabetes.

Am J Clin Nutr. 2009 Feb;89(2):518-24. Epub 2008 Dec 23.PMID: 19106241 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial.

White NH, Sun W, Cleary PA, Danis RP, Davis MD, Hainsworth DP, Hubbard LD, Lachin JM, Nathan DM.

Arch Ophthalmol. 2008 Dec;126(12):1707-15.PMID: 19064853 [PubMed - indexed for MEDLINE]Related articlesFree article

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results.

Mahon JL, Sosenko JM, Rafkin-Mervis L, Krause-Steinrauf H, Lachin JM, Thompson C, Bingley PJ, Bonifacio E, Palmer JP, Eisenbarth GS, Wolfsdorf J, Skyler JS; TrialNet Natural History Committee; Type 1 Diabetes TrialNet Study Group.

Pediatr Diabetes. 2009 Apr;10(2):97-104. Epub 2008 Sep 24.PMID: 18823409 [PubMed - indexed for MEDLINE]Related articles

Insulin therapy, hyperglycemia, and hypertension in type 1 diabetes mellitus.

de Boer IH, Kestenbaum B, Rue TC, Steffes MW, Cleary PA, Molitch ME, Lachin JM, Weiss NS, Brunzell JD; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Group.

Arch Intern Med. 2008 Sep 22;168(17):1867-73.PMID: 18809813 [PubMed - indexed for MEDLINE]Related articlesFree article

Mixed-meal tolerance test versus glucagon stimulation test for the assessment of beta-cell function in therapeutic trials in type 1 diabetes.

Greenbaum CJ, Mandrup-Poulsen T, McGee PF, Battelino T, Haastert B, Ludvigsson J, Pozzilli P, Lachin JM, Kolb H; Type 1 Diabetes Trial Net Research Group; European C-Peptide Trial Study Group.

Diabetes Care. 2008 Oct;31(10):1966-71. Epub 2008 Jul 15.PMID: 18628574 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT).

Kahn SE, Zinman B, Lachin JM, Haffner SM, Herman WH, Holman RR, Kravitz BG, Yu D, Heise MA, Aftring RP, Viberti G; Diabetes Outcome Progression Trial (ADOPT) Study Group.

Diabetes Care. 2008 May;31(5):845-51. Epub 2008 Jan 25.PMID: 18223031 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of glycemic exposure on the risk of microvascular complications in the diabetes control and complications trial--revisited.

Lachin JM, Genuth S, Nathan DM, Zinman B, Rutledge BN; DCCT/EDIC Research Group.

Diabetes. 2008 Apr;57(4):995-1001. Epub 2008 Jan 25.PMID: 18223010 [PubMed - indexed for MEDLINE]Related articlesFree article

A risk score for type 1 diabetes derived from autoantibody-positive participants in the diabetes prevention trial-type 1.

Sosenko JM, Krischer JP, Palmer JP, Mahon J, Cowie C, Greenbaum CJ, Cuthbertson D, Lachin JM, Skyler JS; Diabetes Prevention Trial-Type 1 Study Group.

Diabetes Care. 2008 Mar;31(3):528-33. Epub 2007 Nov 13.PMID: 18000175 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Genetics study.

Al-Kateb H, Boright AP, Mirea L, Xie X, Sutradhar R, Mowjoodi A, Bharaj B, Liu M, Bucksa JM, Arends VL, Steffes MW, Cleary PA, Sun W, Lachin JM, Thorner PS, Ho M, McKnight AJ, Maxwell AP, Savage DA, Kidd KK, Kidd JR, Speed WC, Orchard TJ, Miller RG, Sun L, Bull SB, Paterson AD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group.

Diabetes. 2008 Jan;57(1):218-28. Epub 2007 Oct 3.PMID: 17914031 [PubMed - indexed for MEDLINE]Related articlesFree article

Sample size evaluation for a multiply matched case-control study using the score test from a conditional logistic (discrete Cox PH) regression model.

Lachin JM.

Stat Med. 2008 Jun 30;27(14):2509-23.PMID: 17886235 [PubMed - indexed for MEDLINE]Related articles

A composite design for transition from a preliminary to a full-scale study.

Lachin JM, Younes N.

Stat Med. 2007 Nov 30;26(27):5014-32.PMID: 17577245 [PubMed - indexed for MEDLINE]Related articles

Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program.

Herman WH, Ma Y, Uwaifo G, Haffner S, Kahn SE, Horton ES, Lachin JM, Montez MG, Brenneman T, Barrett-Connor E; Diabetes Prevention Program Research Group.

Diabetes Care. 2007 Oct;30(10):2453-7. Epub 2007 May 29.PMID: 17536077 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of intensive diabetes treatment on resting heart rate in type 1 diabetes: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study.

Paterson AD, Rutledge BN, Cleary PA, Lachin JM, Crow RS; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group.

Diabetes Care. 2007 Aug;30(8):2107-12. Epub 2007 Apr 27.PMID: 17468351 [PubMed - indexed for MEDLINE]Related articlesFree article

Factors associated with diabetes onset during metformin versus placebo therapy in the diabetes prevention program.

Lachin JM, Christophi CA, Edelstein SL, Ehrmann DA, Hamman RF, Kahn SE, Knowler WC, Nathan DM; DDK Research Group.

Diabetes. 2007 Apr;56(4):1153-9.PMID: 17395752 [PubMed - indexed for MEDLINE]Related articlesFree article

The hemoglobin glycation index is not an independent predictor of the risk of microvascular complications in the Diabetes Control and Complications Trial.

Lachin JM, Genuth S, Nathan DM, Rutledge BN.

Diabetes. 2007 Jul;56(7):1913-21. Epub 2007 Mar 14.PMID: 17360979 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.

Kahn SE, Haffner SM, Heise MA, Herman WH, Holman RR, Jones NP, Kravitz BG, Lachin JM, O'Neill MC, Zinman B, Viberti G; ADOPT Study Group.

N Engl J Med. 2006 Dec 7;355(23):2427-43. Epub 2006 Dec 4. Erratum in: N Engl J Med. 2007 Mar 29;356(13):1387-8. PMID: 17145742 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study.

Cleary PA, Orchard TJ, Genuth S, Wong ND, Detrano R, Backlund JY, Zinman B, Jacobson A, Sun W, Lachin JM, Nathan DM; DCCT/EDIC Research Group.

Diabetes. 2006 Dec;55(12):3556-65.PMID: 17130504 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of weight loss with lifestyle intervention on risk of diabetes.

Hamman RF, Wing RR, Edelstein SL, Lachin JM, Bray GA, Delahanty L, Hoskin M, Kriska AM, Mayer-Davis EJ, Pi-Sunyer X, Regensteiner J, Venditti B, Wylie-Rosett J.

Diabetes Care. 2006 Sep;29(9):2102-7.PMID: 16936160 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity is a major determinant of the association of C-reactive protein levels and the metabolic syndrome in type 2 diabetes.

Kahn SE, Zinman B, Haffner SM, O'Neill MC, Kravitz BG, Yu D, Freed MI, Herman WH, Holman RR, Jones NP, Lachin JM, Viberti GC; ADOPT Study Group.

Diabetes. 2006 Aug;55(8):2357-64.PMID: 16873701 [PubMed - indexed for MEDLINE]Related articlesFree article

Parametric survival models for interval-censored data with time-dependent covariates.

Sparling YH, Younes N, Lachin JM, Bautista OM.

Biostatistics. 2006 Oct;7(4):599-614. Epub 2006 Apr 5.PMID: 16597670 [PubMed - indexed for MEDLINE]Related articlesFree article

Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.

Nathan DM, Cleary PA, Backlund JY, Genuth SM, Lachin JM, Orchard TJ, Raskin P, Zinman B; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group.

N Engl J Med. 2005 Dec 22;353(25):2643-53.PMID: 16371630 [PubMed - indexed for MEDLINE]Related articlesFree article

Operating characteristics of sample size re-estimation with futility stopping based on conditional power.

Lachin JM.

Stat Med. 2006 Oct 15;25(19):3348-65.PMID: 16345019 [PubMed - indexed for MEDLINE]Related articles

Maximum information designs.

Lachin JM.

Clin Trials. 2005;2(5):453-64.PMID: 16315649 [PubMed - indexed for MEDLINE]Related articles

The role of measurement reliability in clinical trials.

Lachin JM.

Clin Trials. 2004;1(6):553-66.PMID: 16279296 [PubMed - indexed for MEDLINE]Related articles

A review of methods for futility stopping based on conditional power.

Lachin JM.

Stat Med. 2005 Sep 30;24(18):2747-64. Review.PMID: 16134130 [PubMed - indexed for MEDLINE]Related articles

Biological variation in HbA1c predicts risk of retinopathy and nephropathy in type 1 diabetes: response to McCarter et al.

Genuth S, Lachin JM, Nathan DM.

Diabetes Care. 2005 Jan;28(1):233; author reply 234-5. No abstract available. PMID: 15616268 [PubMed - indexed for MEDLINE]Related articlesFree article

Conflicts of interest in data monitoring of industry versus publicly financed clinical trials.

Lachin JM.

Stat Med. 2004 May 30;23(10):1519-21.PMID: 15122730 [PubMed - indexed for MEDLINE]Related articles

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.

Palmer JP, Fleming GA, Greenbaum CJ, Herold KC, Jansa LD, Kolb H, Lachin JM, Polonsky KS, Pozzilli P, Skyler JS, Steffes MW.

Diabetes. 2004 Jan;53(1):250-64. Erratum in: Diabetes. 2004 Jul;53(7):1934. PMID: 14693724 [PubMed - indexed for MEDLINE]Related articlesFree article

Group sequential large sample T2-like chi2 tests for multivariate observations.

Lachin JM, Greenhouse SW, Bautista OM.

Stat Med. 2003 Nov 15;22(21):3357-68.PMID: 14566920 [PubMed - indexed for MEDLINE]Related articles

Over-ruling a group sequential boundary--a stopping rule versus a guideline.

Lan KK, Lachin JM, Bautista O.

Stat Med. 2003 Nov 15;22(21):3347-55.PMID: 14566919 [PubMed - indexed for MEDLINE]Related articles

A tribute to Samuel W. Greenhouse.

Lachin JM.

Stat Med. 2003 Nov 15;22(21):3267-76. No abstract available. PMID: 14566909 [PubMed - indexed for MEDLINE]Related articles

Costs associated with the primary prevention of type 2 diabetes mellitus in the diabetes prevention program.

Hernan WH, Brandle M, Zhang P, Williamson DF, Matulik MJ, Ratner RE, Lachin JM, Engelgau MM; Diabetes Prevention Program Research Group.

Diabetes Care. 2003 Jan;26(1):36-47.PMID: 12502656 [PubMed - indexed for MEDLINE]Related articlesFree article

A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes.

Viberti G, Kahn SE, Greene DA, Herman WH, Zinman B, Holman RR, Haffner SM, Levy D, Lachin JM, Berry RA, Heise MA, Jones NP, Freed MI.

Diabetes Care. 2002 Oct;25(10):1737-43.PMID: 12351470 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM; Diabetes Prevention Program Research Group.

N Engl J Med. 2002 Feb 7;346(6):393-403.PMID: 11832527 [PubMed - indexed for MEDLINE]Related articlesFree article

Application of robust estimating equations to the analysis of quantitative longitudinal data.

Hu M, Lachin JM.

Stat Med. 2001 Nov 30;20(22):3411-28.PMID: 11746326 [PubMed - indexed for MEDLINE]Related articles

A flexible stochastic curtailing procedure for the log-rank test.

Bautista OM, Bain RP, Lachin JM.

Control Clin Trials. 2000 Oct;21(5):428-39.PMID: 11018561 [PubMed - indexed for MEDLINE]Related articles

Statistical considerations in the intent-to-treat principle.

Lachin JM.

Control Clin Trials. 2000 Jun;21(3):167-89. Erratum in: Control Clin Trials 2000 Oct;21(5):526. PMID: 10822117 [PubMed - indexed for MEDLINE]Related articles

Worst-rank score analysis with informatively missing observations in clinical trials.

Lachin JM.

Control Clin Trials. 1999 Oct;20(5):408-22. Review.PMID: 10503801 [PubMed - indexed for MEDLINE]Related articles

Group sequential monitoring of distribution-free analyses of repeated measures.

Lachin JM.

Stat Med. 1997 Mar 30;16(6):653-68.PMID: 9131754 [PubMed - indexed for MEDLINE]Related articles

The efficacy of tolrestat in the treatment of diabetic peripheral neuropathy. A meta-analysis of individual patient data.

Nicolucci A, Carinci F, Graepel JG, Hohman TC, Ferris F, Lachin JM.

Diabetes Care. 1996 Oct;19(10):1091-6.PMID: 8886554 [PubMed - indexed for MEDLINE]Related articles

Nonparametric test of stochastic ordering for multiple longitudinal measures.

Rosenberger WF, Lachin JM, Bain RP.

J Biopharm Stat. 1995 Nov;5(3):235-43.PMID: 8580926 [PubMed - indexed for MEDLINE]Related articles

Sequential monitoring of survival data with the Wilcoxon statistic.

Lan KK, Rosenberger WF, Lachin JM.

Biometrics. 1995 Sep;51(3):1175-83.PMID: 7548701 [PubMed - indexed for MEDLINE]Related articles